The mammalian brain is one of the most intricate entities in the universe. Beneath this remarkable complexity, we hold the belief that fundamental and discernible principles govern the diverse neural dynamics, brain functions, and behaviours. The long-range goal of our lab is to develop and use cutting-edge neural technologies to investigate these principles - the algorithms at work within the brain.

Aim

By developing cutting-edge optical technologies to monitor and perturbate neuronal activity in freely behaving animals, we aim to provide insights into the neural mechanisms underlying a wide range of brain functions.

Key research questions

1. How is information encoded and transmitted within a single brain microcircuit?

2. What is the role of diverse cell types, synaptic connectivity, and single-cell firing properties in the functions of specific brain microcircuits?

Tools & Methods

• Cutting-edge optics and micro-electronics devices
• Miniature multiphoton microscopes
• Large-scale calcium/voltage imaging in freely-moving mice
• All-optical electrophysiology
• Large-scale imaging data processing and analysis

For more information please visit our lab's external website: zong-lab.com