Publications associated with Genomics Core Facility (GCF) 2000-2023

 

2023

Zajac GJM, Gagliano Taliun SA, Sidore C, Graham SE, Åsvold BO, Brumpton B, Nielsen JB, Zhou W, Gabrielsen M, Skogholt AH, Fritsche LG, Schlessinger D, Cucca F, Hveem K, Willer CJ, Abecasis GR. A fast linkage method for population GWAS cohorts with related individuals. Genet Epidemiol. 2023 Apr;47(3):231-248. doi: 10.1002/gepi.22516. Epub 2023 Feb 5. PMID: 36739617

Solé-Navais P, Flatley C, et al. Genetic effects on the timing of parturition and links to fetal birth weight. Nat Genet. 2023 Apr;55(4):559-567. doi: 10.1038/s41588-023-01343-9. Epub 2023 Apr 3. PMID: 37012456

Surakka I, Wu KH, Hornsby W, Wolford BN, Shen F, Zhou W, Huffman JE, Pandit A, Hu Y, Brumpton B, Skogholt AH, Gabrielsen ME, Walters RG; TOPMed Stroke Working Group; Million Veteran Program (MVP); Hveem K, Kooperberg C, Zöllner S, Wilson PWF, Sutton NR, Daly MJ, Neale BM, Willer CJ; Global Biobank Meta-analysis Initiative (GBMI). Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries. Cell Genom. 2023 Jun 19;3(8):100345. doi: 10.1016/j.xgen.2023.100345. eCollection 2023 Aug 9. PMID: 37601974

Lagou V, Jiang L, Ulrich A et al. GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. Nat Genet. 2023 Sep;55(9):1448-1461. doi: 10.1038/s41588-023-01462-3. Epub 2023 Sep 7. PMID: 37679419

Feng X, Wu WY, et al.- Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools. J Natl Cancer Inst. 2023 Sep 7;115(9):1050-1059. doi: 10.1093/jnci/djad071. PMID: 37260165

McSweeney SM, Saklatvala J, Rispoli R, Ganier C, Woszczek G, Thomas L, Hveem K, Løset M, Dand N, Tziotzios C, Simpson M, McGrath JA. Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria. J Allergy Clin Immunol. 2023 Sep 8:S0091-6749(23)01117-X. doi: 10.1016/j.jaci.2023.08.033. Online ahead of print. PMID: 37690594

Eikrem Ø, Lillefosse B, Delaleu N, Strauss P, Osman T, Vikse BE, Debiec H, Ronco P, Sekulic M, Koch E, Furriol J, Leh SM, Marti HP. Network-Based Assessment of Minimal Change Disease Identifies Glomerular Response to IL-7 and IL-12 Pathways Activation as Innovative Treatment Target. Biomedicines. 2023 Jan 16;11(1):226. doi: 10.3390/biomedicines11010226. PMID: 36672735

Delaleu N, Marti HP, Strauss P, Sekulic M, Osman T, Tøndel C, Skrunes R, Leh S, Svarstad E, Nowak A, Gaspert A, Rusu E, Kwee I, Rinaldi A, Flatberg A, Eikrem O. Systems analyses of the Fabry kidney transcriptome and its response to enzyme replacement therapy identified and cross-validated enzyme replacement therapy-resistant targets amenable to drug repurposing. Kidney Int. 2023 Jul 5:S0085-2538(23)00487-8. doi: 10.1016/j.kint.2023.06.029. Online ahead of print. PMID: 37419447

Therese Haugdahl Nøst, Anne Heidi Skogholt, Ilona Urbarova, Robin Mjelle, Erna-Elise Paulsen, Tom Dønnem, Sigve Andersen, Maria Markaki, Oluf Dimitri Røe, Mikael Johansson, Mattias Johansson, Bjørn Henning Grønberg, Torkjel Manning Sandanger, Pål Saetrom. Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Mol Oncol. 2023 Feb;17(2):312-327. doi: 10.1002/1878-0261.13336. Epub 2022 Nov 27.PMID: 36337027 PMCID: PMC9892825 DOI: 10.1002/1878-0261.13336

Nøst TH, Skogholt AH, Urbarova I, Mjelle R, Paulsen EE, Dønnem T, Andersen S, Markaki M, Røe OD, Johansson M, Johansson M, Grønberg BH, Sandanger TM, Saetrom P. Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Mol Oncol. 2023 Feb;17(2):312-327. doi: 10.1002/1878-0261.13336. Epub 2022 Nov 27. PMID: 36337027

Olsen LC, Galler M, Witter MP, Saetrom P, O'Reilly KC. Transcriptional development of the hippocampus and the dorsal-intermediate-ventral axis in rats. Hippocampus. 2023 Sep;33(9):1028-1047. doi: 10.1002/hipo.23549. Epub 2023 Jun 6. PMID: 37280038

Baiju N, Rylander C, Saetrom P, Sandanger TM, Nøst TH. Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort. Obesity (Silver Spring). 2023 Sep;31(9):2417-2429. doi: 10.1002/oby.23836. Epub 2023 Aug 7. PMID: 37548254

Walaas GA, Gopalakrishnan S, Bakke I, Skovdahl HK, Flatberg A, Østvik AE, Sandvik AK, Bruland T. Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Front Immunol. 2023 Jan 27;14:1095812. doi: 10.3389/fimmu.2023.1095812. eCollection 2023. PMID: 36793710

Ida Surakka, Brooke N Wolford, Scott C Ritchie et al. Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction. Circ Genom Precis Med . 2023 Feb;16(1):e003542. doi: 10.1161/CIRCGEN.121.003542. Epub 2022 Dec 29.

Mark K Bakker, Jos P Kanning, Gad Abraham et al. Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity. Stroke. 2023 Mar;54(3):810-818. Epub 2023 Jan 19. PMID: 36655558 PMCID: PMC9951795 DOI: 10.1161/STROKEAHA.122.040715

 

2022

Marta R Moksnes, Sarah E Graham, Kuan-Han Wu et al. Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT. Commun Biol. 2022 Jun 16;5(1):591. PMID: 35710628 PMCID: PMC9203493 DOI: 10.1038/s42003-022-03529-z

Christopher A Cockerill, Malin Hasselgren, Nicolas Dussex, Love Dalén, Johanna von Seth, Anders Angerbjörn, Johan F Wallén, Arild Landa, Nina E Eide, Øystein Flagstad, Dorothee Ehrich, Aleksandr Sokolov, Natalya Sokolova, Karin Norén . Genomic Consequences of Fragmentation in the Endangered Fennoscandian Arctic Fox (Vulpes lagopus). Genes (Basel). 2022 Nov 15;13(11):2124. PMID: 36421799 PMCID: PMC9690288 DOI: 10.3390/genes13112124

Christine Klykken, Lauris Boissonnot, Anne Katrine Reed, Paul Whatmore, Kari Attramadal, Rolf Erik Olsen. Gene expression patterns in Atlantic salmon (Salmo salar) with severe nephrocalcinosis. J Fish Dis. 2022 Nov;45(11):1645-1658. PMID: 35862221 PMCID: PMC9796406 DOI: 10.1111/jfd.13687

Åshild Ø Solvin, Konika Chawla, Lene C Olsen, Siv Anita Hegre, Kjersti Danielsen, Marita Jenssen, Anne-Sofie Furberg, Marit Saunes, Kristian Hveem, Pål Saetrom, Mari Løset. MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Exp Dermatol. 2022 Apr;31(4):535-547. PMID: 34748247 DOI: 10.1111/exd.14497

Siri Sæterstad, Ann Elisabet Østvik, Elin Synnøve Røyset, Ingunn Bakke, Arne Kristian Sandvik, Atle van Beelen Granlund. Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease PLoS One. 2022 Mar 11;17(3):e0265189. PMID: 35275975 PMCID: PMC8916644 DOI: 10.1371/journal.pone.0265189

Brittany L Mitchell, Jake R Saklatvala, Nick Dand et al. Genome-wide association meta-analysis identifies 29 new acne susceptibility loci. Nat Commun. 2022 Feb 7;13(1):702.PMID: 35132056 PMCID: PMC8821634 DOI: 10.1038/s41467-022-28252-5

Heidi Hautakangas, Bendik S Winsvold, Sanni E Ruotsalainen et al.Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. Nat Genet. 2022 Feb;54(2):152-160. Epub 2022 Feb 3. PMID: 35115687 PMCID: PMC8837554 DOI: 10.1038/s41588-021-00990-0

Ben M Brumpton, Sarah Graham, Ida Surakka, Anne Heidi Skogholt et al. The HUNT study: A population-based cohort for genetic research. Cell Genom. 2022 Oct 12;2(10):100193. PMID: 36777998 PMCID: PMC9903730 DOI: 10.1016/j.xgen.2022.100193

Nina Mars, Sini Kerminen, Yen-Chen A Feng et al. Genome-wide risk prediction of common diseases across ancestries in one million people. Cell Genom. 2022 Apr 13;2(4):None. doi: 10.1016/j.xgen.2022.100118. PMID: 35591975 PMCID: PMC9010308

Bjornsdottir G, Stefansdottir L, Thorleifsson G et al. Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology. Nat Commun. 2022 Feb 2;13(1):634. doi: 10.1038/s41467-022-28167-1. PMID: 35110524

Heidi Hautakangas, Bendik S Winsvold et al. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. Nat Genet. 2022 Feb;54(2):152-160. doi: 10.1038/s41588-021-00990-0. Epub 2022 Feb 3. PMID: 35115687 PMCID: PMC8837554

Therese Haugdahl Nøst, Anne Heidi Skogholt, Ilona Urbarova, Robin Mjelle, Erna-Elise Paulsen, Tom Dønnem, Sigve Andersen, Maria Markaki, Oluf Dimitri Røe, Mikael Johansson, Mattias Johansson, Bjørn Henning Grønberg, Torkjel Manning Sandanger, Pål Saetrom. Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Mol Oncol. 2023 Feb;17(2):312-327. doi: 10.1002/1878-0261.13336. Epub 2022 Nov 27.PMID: 36337027 PMCID: PMC9892825 DOI: 10.1002/1878-0261.13336

Olaisen M, Richard ML, Beisvåg V, Granlund AVB, Røyset ES, Rué O, Martinsen TC, Sandvik AK, Sokol H, Fossmark R. The ileal fungal microbiota is altered in Crohn's disease and is associated with the disease course. Front Med (Lausanne). 2022 Sep 27;9:868812. doi: 10.3389/fmed.2022.868812. eCollection 2022. PMID: 36237548

Kristine Misund, Davine Hofste op Bruinink, Eivind Coward, Remco M. Hoogenboezem, Even Holth Rustad, Mathijs A. Sanders, Morten Rye, Anne-Marit Sponaas, Bronno van der Holt, Sonja Zweegman, Eivind Hovig, Leonardo A. Meza-Zepeda, Anders Sundan, Ola Myklebost, Pieter Sonneveld & Anders Waage. Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia volume 36, pages1887–1897 (2022)

Philipp Strauss, Mariell Rivedal, Andreas Scherer, Øystein Eikrem, Sigrid Nakken, Christian Beisland, Leif Bostad, Arnar Flatberg, Eleni Skandalou, Vidar Beisvåg, Jessica Furriol, Hans-Peter. A multiomics disease progression signature of low-risk ccRCC. MartiScientific Reports 12 (1), 1-15    2022.

EP Sørgjerd, R Mjelle, V Beisvåg, A Flatberg, V Grill, BO Åsvold. Small RNAs are differentially expressed in autoimmune and non-autoimmune diabetes and controls. European journal of endocrinology 187 (2), 231-240    2022.

P Strauss, M Rivedal, A Scherer, O Eikrem, S Nakken, C Beisland, L Bostad, A Flatberg, E Skandalou, V Beisvag, J Furriol, HP Marti. Characterisation of disease progression in low-risk renal cell carcinoma patients by multiomics data. EUROPEAN UROLOGY 81, S1650-S1650 2022

I Catalan-Serra, S Thorsvik, V Beisvag, T Bruland, D Underhill, AK Sandvik, A Granlund, Van Beelen. Fungal microbiota composition in Inflammatory Bowel Disease patients in a Norwegian cohort: characterization of disease phenotypes and correlation with clinical activity. JOURNAL OF CROHNS & COLITIS 16, I608-I609 2022.

Florian Thibord, Derek Klarin, Jennifer A Brody et al. Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors. Circulation. 2022 Oct 18;146(16):1225-1242. doi: 10.1161/CIRCULATIONAHA.122.059675. Epub 2022 Sep 26.. PMID: 36154123 DOI: 

 

2021

Hanne-Line Rabben, Gøran Troseth Andersen, Aleksandr Ianevski, Magnus Kringstad Olsen, Denis Kainov, Jon Erik Grønbech, Timothy Cragin Wang, Duan Chen, Chun-Mei Zhao. Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Front Pharmacol. 2021 Mar 31;12:625991. PMID: 33867984 PMCID: PMC8044519 DOI: 10.3389/fphar.2021.625991

Olaf Strømme, Kathleen A Heck, Gaute Brede, Håvard T Lindholm, Marit Otterlei, Carl-Jørgen Arum. Differentially Expressed Extracellular Vesicle-Contained microRNAs before and after Transurethral Resection of Bladder Tumors. Curr Issues Mol Biol. 2021 Jun 4;43(1):286-300. PMID: 34199766 PMCID: PMC8929081 DOI: 10.3390/cimb43010024

Larsen SV, Holven KB, Christensen JJ, Flatberg A, Rundblad A, Leder L, Blomhoff R, Telle-Hansen V, Kolehmainen M, Carlberg C, Myhrstad MC, Thoresen M, Ulven SM. Replacing Saturated Fat with Polyunsaturated Fat Modulates Peripheral Blood Mononuclear Cell Gene Expression and Pathways Related to Cardiovascular Disease Risk Using a Whole Transcriptome Approach. Mol Nutr Food Res. 2021 Dec;65(24):e2100633. doi: 10.1002/mnfr.202100633. Epub 2021 Nov 15. PMID: 34708513

Roxane Monnoyer 1, Ingrid Eftedal 1 2, Astrid Hjelde 1, Sanjoy Deb 1 3, Kjersti Haugum 4 5, Jacky Lautridou 1. Functional Profiling Reveals Altered Metabolic Activity in Divers' Oral Microbiota During Commercial Heliox Saturation Diving. Front Physiol. 2021 Oct 13;12:702634. doi: 10.3389/fphys.2021.702634. eCollection 2021. PMID: 34721054 PMCID: PMC8548618 DOI: 10.3389/fphys.2021.702634

Kristin Roseth Aass 1 2, Robin Mjelle 2, Martin H Kastnes 1 2, Synne S Tryggestad 1 2, Luca M van den Brink 1, Ingrid Aass Roseth 1 2, Marita Westhrin 1, Muhammad Zahoor 3, Siv H Moen 1 2, Tonje M Vikene Nedal 1 2, Glenn Buene 1 2, Kristine Misund 2, Anne-Marit Sponaas 2, Qianli Ma 1 2, Anders Sundan 1 2, Richard Wj Groen 4, Tobias S Slørdahl 2 5, Anders Waage 2 5, Therese Standal 1 2 5. Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells. iScience. 2021 Dec 13;25(1):103605. doi: 10.1016/j.isci.2021.103605. eCollection 2022 Jan 21. PMID: 35005550 PMCID: PMC8717606 DOI: 10.1016/j.isci.2021.103605.

Marie Louise Davey 1, Kjersti Selstad Utaaker 2 3, Frode Fossøy 2. Characterizing parasitic nematode faunas in faeces and soil using DNA metabarcoding. Parasit Vectors. 2021 Aug 21;14(1):422. doi: 10.1186/s13071-021-04935-8. PMID: 34419166 PMCID: PMC8380370 DOI: 10.1186/s13071-021-04935-8

Mie Jareid 1, Igor Snapkov 2, Marit Holden 3, Lill-Tove Rasmussen Busund 4, Eiliv Lund 1 5, Therese Haugdahl Nøst 1. The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PLoS One. 2021 Aug 27;16(8):e0256442. doi: 10.1371/journal.pone.0256442. eCollection 2021.

Therese H Nøst 1, Marit Holden 2, Tom Dønnem 3 4, Hege Bøvelstad 5, Charlotta Rylander 6, Eiliv Lund 6 7, Torkjel M Sandanger 6. Transcriptomic signals in blood prior to lung cancer focusing on time to diagnosis and metastasis. Sci Rep. 2021 Apr 1;11(1):7406. doi: 10.1038/s41598-021-86879-8. PMID: 33795786 PMCID: PMC8017014 DOI: 10.1038/s41598-021-86879-8

Esten Nymoen Vandsemb, Morten Beck Rye, Ida Johnsen Steiro , Samah Elsaadi, Torstein Bade Rø, Tobias Schmidt Slørdahl, Anne-Marit Sponaas, Magne Børset, Pegah Abdollahi. PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2. FEBS J. 2021 Dec;288(23):6700-6715. doi: 10.1111/febs.16058. Epub 2021 Jun 20. PMID: 34092011 DOI: 10.1111/febs.16058

Anders Tøndell 1 2, Yashwanth Subbannayya 2 3, Sissel Gyrid Freim Wahl 2 4, Arnar Flatberg 2 5, Sveinung Sørhaug 1, Magne Børset 2 6, Markus Haug 2 3 7. Analysis of Intra-Tumoral Macrophages and T Cells in Non-Small Cell Lung Cancer (NSCLC) Indicates a Role for Immune Checkpoint and CD200-CD200R Interactions. Cancers. 2021 Apr 9;13(8):1788. doi: 10.3390/cancers13081788. PMID: 33918618 PMCID: PMC8069596

Roxane Monnoyer, Kjersti Haugum, Jacky Lautridou, Arnar Flatberg, Astrid Hjelde, Ingrid Eftedal. Shifts in the Oral Microbiota During a Four-Week Commercial Saturation Dive to 200 Meters. Front Physiol. 2021 Apr 27;12:669355. doi: 10.3389/fphys.2021.669355. eCollection 2021. PMID: 33986696 PMCID: PMC8110926 DOI: 10.3389/fphys.2021.669355.

Yi-Qian Sun, Rebecca C Richmond, Matthew Suderman, Josine L Min, Thomas Battram, Arnar Flatberg, Vidar Beisvag, Therese Haugdahl Nøst, Florence Guida, Lin Jiang, Sissel Gyrid Freim Wahl, Arnulf Langhammer, Frank Skorpen, Rosie M Walker, Andrew D Bretherick, Yanni Zeng, Yue Chen, Mattias Johansson, Torkjel M Sandanger, Caroline L Relton, Xiao-Mei Mai. Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT study. Int J Epidemiol. 2021 Nov 10;50(5):1482-1497. doi: 10.1093/ije/dyab044.PMID: 33729499 PMCID: PMC8580278 DOI: 10.1093/ije/dyab044

Bakker MK, van der Spek RAA, van Rheenen W et al. Author Correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors. Nat Genet. 2021 Feb;53(2):254. doi: 10.1038/s41588-020-00760-4. PMID: 33353957

Baiju N, Sandanger TM, Sætrom P, Nøst TH. Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Sci Rep. 2021 Jan 12;11(1):680. doi: 10.1038/s41598-020-80158-8. PMID: 33436844

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B. Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Res. 2021 Jan 14:gkaa1289. doi: 10.1093/nar/gkaa1289. Online ahead of print. PMID: 33444446

Nakken, Sigrid; Eikrem, Øystein Solberg; Marti, Hans Peter; Beisland, Christian; Bostad, Leif; Scherer, Andreas; Flatberg, Arnar; Beisvag, Vidar; Skandalou, Eleni; Furriol, Jessica; Strauss, Philipp. AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease. Cancer Cell International 2021 ;Volum 21. s. -

Olaisen, Maya; Richard, Mathias L; Beisvag, Vidar; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Martinsen, Tom Christian; Sandvik, Arne Kristian; Sokol, Harry; Fossmark, Reidar. Fungal microbiota in the ileal mucosa of patients with Crohn’s disease. United european gastroenterology Week; 2021-10-02 - 2021-10-06

Zaytseva-Zotova, Daria; Haslene-Hox, Hanne; Arlov, Øystein; Vikenes, Anette; Hoel, Andrea Draget; Chahal, Aman S; Mjelle, Robin; Strand, Wenche Iren; Akbarzadeh, Anita; Klinkenberg, Geir; Halaas, Øyvind; Beisvag, Vidar; Sletta, Håvard; Sætrom, Pål; Strand, Berit Løkensgard. Alginate Hydrogel Characteristics Regulate Dermal Fibroblasts Biology. ScSB 2021; 2021-06-14 - 2021-06-14

Olaisen M, Flatberg A, Granlund A vB, Røyset ES, Martinsen TC, Sandvik AK, Fossmark R. Bacterial mucosa-associated microbiome in inflamed and proximal non-inflamed ileum of patients with Crohn’s disease. Inflammatory Bowel Diseases, 2021, 27(1), 12-24.

Escudero-Hernández C, Granlund AvB, Bruland T, Sandvik AK, Koch S, Østvik AE, Münch A. Transcriptomic profiling of collagenous colitis identifies hallmarks of non-destructive inflammatory bowel disease. Cell Mol Gastroenterol Hepatol 2021, 12(2), 665-687.

Helene Kolstad Skovdahl 1 2, Shreya Gopalakrishnan 1, Tarjei Dahl Svendsen 1, Atle van Beelen Granlund 1 2, Ingunn Bakke 1 3, Zekarias G Ginbot 1, Silje Thorsvik 1 2 4, Arnar Flatberg 1 5, Bjørnar Sporsheim 1 5, Jenny Ostrop 1 2, Tom Eirik Mollnes 2 6 7 8, Arne Kristian Sandvik 1 2 4, Torunn Bruland 1 9. Affiliations expand. Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration. Front Pharmacol. 2021 May 13;12:679741. doi: 10.3389/fphar.2021.679741. eCollection 2021. PMID: 34054553

Bakke I, Walaas GA, Bruland T, Røyset ES, Granlund AvB, Escudero-Hernández C, Silje Thorsvik S, Münch A, Sandvik AK, Østvik AE. Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. J Gastroenterol 2021, 56(10), 914-927

Bakker MK, van der Spek RAA, van Rheenen W et al. Author Correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors. Nat Genet. 2021 Feb;53(2):254. doi: 10.1038/s41588-020-00760-4. PMID: 33353957

Baiju N, Sandanger TM, Sætrom P, Nøst TH. Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Sci Rep. 2021 Jan 12;11(1):680. doi: 10.1038/s41598-020-80158-8. PMID: 33436844

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B. Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Res. 2021 Jan 14:gkaa1289. doi: 10.1093/nar/gkaa1289. Online ahead of print. PMID: 33444446

Olaisen M, Flatberg A, Granlund A vB, Røyset ES, Martinsen TC, Sandvik AK, Fossmark R. Bacterial mucosa-associated microbiome in inflamed and proximal non-inflamed ileum of patients with Crohn’s disease. Inflammatory Bowel Diseases, in press- doi:10.1093/ibd/izaa107

Hegre SA, Samdal H, Klima A, Stovner EB, Nørsett KG, Liabakk NB, Olsen LC, Chawla K, Aas PA, Sætrom P. Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Sci Rep. 2021 Sep 23;11(1):18952. doi: 10.1038/s41598-021-97909-w.

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B. Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Res. 2021 Feb 22;49(3):1470-1484. doi: 10.1093/nar/gkaa1289.

Wightman DP, Jansen IE, Savage JE et al. A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. Nat Genet. 2021 Sep;53(9):1276-1282. doi: 10.1038/s41588-021-00921-z. Epub 2021 Sep 7. PMID: 34493870

 

2020

Nathan Robert Scrimgeour 1 2, Aleksandra Wrobel 1 2, Maria João Pinho 1 2, Morten Andre Høydal 1 2. microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation Am J Physiol Cell Physiol. 2020 Jan 1;318(1):C94-C102. doi: 10.1152/ajpcell.00204.2019. Epub 2019 Oct 16. PMID: 31618079 DOI: 10.1152/ajpcell.00204.2019

Jørandli JW, Thorsvik S, Kornfeld B, Skovdal HK, Sæterstad S, Gustafsson BI, Sandvik AK, Granlund A vB. The serotonin reuptake transporter (SERT) is reduced in the epithelium of active Crohn’s disease and ulcerative colitis. American Journal of Physiology 2020, 319(6), G761-G768.

Escudero-Hernández C, Münch A, Østvik AE, Granlund AvB, Koch S. The water channel Aquaporin 8 is a critical regulator of intestinal fluid homeostasis in collagenous colitis. J Crohns Colitis 2020, 14(7), 962-973.

Ottestad AL, Wahl SGF, Grønberg BH, Skorpen F, Dai HY. The relevance of tumor mutation profiling in interpretation of NGS data from cell-free DNA in non-small cell lung cancer patients. Exp Mol Pathol. 2020 Feb;112:104347. doi: 10.1016/j.yexmp.2019.104347.

Skottene, Elise; Tarrant, Ann M.; Altin, Dag; et al. Lipid metabolism in Calanus finmarchicus is sensitive to variations in predation risk and food availability SCIENTIFIC REPORTS Volume: ‏ 10Issue: ‏1 Article Number: 22322 Published: ‏ DEC 18 2020

Khan, Essa A.; Zhang, Xiaokang; Hanna, Eileen M.; et al.Quantitative transcriptomics, and lipidomics in evaluating ovarian developmental effects in Atlantic cod (Gadus morhua) caged at a capped marine waste disposal site. ENVIRONMENTAL RESEARCH Volume: ‏ 189Article Number: 109906 Published: ‏OCT 2020

Anja Bye, Marie Klevjer, Einar Ryeng, Gustavo Jose Justo da Silva, Jose Bianco Nascimento Moreira, Dorthe Stensvold, Ulrik Wisløff. Identification of novel genetic variants associated with cardiorespiratory fitness. PROGRESS IN CARDIOVASCULAR DISEASES Volume: ‏ 6 Issue: ‏ 3Pages: ‏ 341-349Published: ‏MAY-JUN 2020

Ottestad, Anine Larsen; Wahl, Sissel G. F.; Gronberg, Bjorn Henning; et al.The relevance of tumor mutation profiling in interpretation of NGS data from cell-free DNA in non-small cell lung cancer patients. EXPERIMENTAL AND MOLECULAR PATHOLOGY Volume: ‏ 112Article Number: 104347 Published: ‏FEB 2020

Barkovskaya, Anna; Seip, Kotryna; Prasmickaite, Lina; et al. Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells. SCIENTIFIC REPORTS Volume: ‏ 10Issue: ‏ 1Article Number: 16992 Published: ‏OCT 12 2020

Zwiggelaar, Rosalie T.; Lindholm, Havard T.; Fosslie, Madeleine; et al. LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. SCIENCE ADVANCES Volume: ‏ 6 Issue: ‏ 37Article Number: eabc0367 Published: ‏SEP 2020

Bye, Anja; Klevjer, Marie; Ryeng, Einar; et al. Identification of novel genetic variants associated with cardiorespiratory fitness. PROGRESS IN CARDIOVASCULAR DISEASES Volume: ‏ 63Issue: ‏  Pages: ‏ 341-349 Published:  MAY-JUN 2020

Rounge, Trine B.; Lauritzen, Marianne; Erlandsen, Sten Even; et al. Ultralow amounts of DNA from long-term archived serum samples produce quality genotypes. EUROPEAN JOURNAL OF HUMAN GENETICS Volume: ‏ 28Issue: ‏ 4Pages: ‏ 521-524Published: ‏APR 2020

Ottestad, Anine Larsen; Wahl, Sissel G. F.; Gronberg, Bjorn Henning; et al. The relevance of tumor mutation profiling in interpretation of NGS data from cell-free DNA in non-small cell lung cancer patients. EXPERIMENTAL AND MOLECULAR PATHOLOGY Volume: ‏ 112Article Number: 104347 Published: ‏FEB 2020

Nakken, Sigrid; Eikrem, Øystein; Marti, Hans-Peter; Beisland, Christian; Bostad, Leif; Scherer, Andreas; Flatberg, Arnar; Beisvag, Vidar; Strauss, Philipp. AGAP2-AS1 as a potential marker for development of distant metastases in surgically treated low-risk clear cell renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2020, Vol.38(6_suppl), p.732-732

S Nakken, Ø Eikrem, HP Marti, C Beisland, A Scherer, V Beisvag, A Flatberg, P Strauss. Transcriptomic characterization of renal cell carcinoma patients with progressive disease despite low initial risk of progression. European Urology Open Science 19, e1479 2020

KM Aasarød, HL Waldum, AK Stunes, AK Sandvik, A Flatberg, P Mjønes et. al. Gastric corpus mucosal hyperplasia and neuroendocrine cell hyperplasia, but not Spasmolytic polypeptide-expressing metaplasia, is prevented by a Gastrin receptor antagonist in H+/K+ATPase beta subunit knockout mice. International journal of molecular sciences 21 (3), 927 2020

Ann Elisabet Østvik, Tarjei Dahl Svendsen, Atle van Beelen Granlund, Berit Doseth , Helene Kolstad Skovdahl, Ingunn Bakke, Silje Thorsvik, Wahida Afroz, Gunnar Andreas Walaas, Tom Eirik Mollnes, Björn Inge Gustafsson, Arne Kristian Sandvik, Torunn Bruland. Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn's Disease. J Crohns Colitis . 2020 Jul 30;14(7):920-934. doi: 10.1093/ecco-jcc/jjaa022. PMID: 32020185 PMCID: PMC7392169 DOI: 10.1093/ecco-jcc/jjaa022

F Fossøy, H Brandsegg, R Sivertsgård, O Pettersen, BK Sandercock, et. al. Monitoring presence and abundance of two gyrodactylid ectoparasites and their salmonid hosts using environmental DNA. Environmental DNA 2 (1), 53-62

Mjelle R, Aass KR, Sjursen W, Hofsli E, Sætrom P. sMETASeq: Combined Profiling of Microbiota and Host Small RNAs. iScience. 2020 May 22;23(5):101131. doi: 10.1016/j.isci.2020.101131. Epub 2020 May 4. PMID: 32422595

A Sankar, M Lerdrup, A Manaf, JV Johansen, JM Gonzalez, R Borup, et. al. KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes. Nat Cell Biol 2020 Apr;22(4):380-388. doi: 10.1038/s41556-020-0494-z. Epub 2020 Mar 30.

M Fosslie, A Manaf, M Lerdrup, K Hansen, GD Gilfillan, JA Dahl. Going low to reach high: Small‐scale ChIP‐seq maps new terrain. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (1), e1465 Wiley Interdiscip Rev Syst Biol Med. 2020 Jan;12(1):e1465. doi: 10.1002/wsbm.1465.

Nielsen JB, Rom O, Surakka I, Graham SE, Zhou W, Hveem K. et al. Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nat Commun. 2020 Dec 18;11(1):6417. doi: 10.1038/s41467-020-20086-3. PMID: 33339817 

Bakker MK, van der Spek RAA, van Rheenen Hveem K et al. Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors. Nat Genet. 2020 Dec;52(12):1303-1313. doi: 10.1038/s41588-020-00725-7. Epub 2020 Nov 16. PMID: 33199917

Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Gabrielsen ME, Skogholt AH, Hveem K, et a. GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2020 Aug 7;11(1):3981. doi: 10.1038/s41467-020-17718-z. PMID: 32769997 

Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Gabrielsen ME, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, et al. Age-of-onset information helps identify 76 genetic variants associated with allergic disease. PLoS Genet. 2020 Jun 30;16(6):e1008725. doi: 10.1371/journal.pgen.1008725. eCollection 2020 Jun. PMID: 32603359

Zhou W, Zhao Z, Nielsen JB, Fritsche LG, LeFaive J, Gagliano Taliun SA, Bi W, Gabrielsen ME, Daly MJ, Neale BM, Hveem K, Abecasis GR, Willer CJ, Lee S. Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts. Nat Genet. 2020 Jun;52(6):634-639. doi: 10.1038/s41588-020-0621-6. Epub 2020 May 18. PMID: 32424355

 

2019

Even Koch 1, Kenneth Finne 1, Øystein Eikrem 1 2, Lea Landolt 1, Christian Beisland 1 3, Sabine Leh 1 4, Nicolas Delaleu 5 6, Magnus Granly 1, Bjørn Egil Vikse 1, Tarig Osman 1, Andreas Scherer 7 8, Hans-Peter Marti 1 2. Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms. Am J Physiol Renal Physiol. 2019 May 1;316(5):F1053-F1067. doi: 10.1152/ajprenal.00424.2018. Epub 2019 Mar 6. PMID: 30838877 DOI: 10.1152/ajprenal.00424.2018

Tricia L Larose 1 2, Pål Sætrom 1 3 4 5, Marit P Martinussen 3, Håkon Skogseth 6, Torkjel M Sandanger 7, Ghislaine Scélo 8, Cliona M McHale 9, Geir W Jacobsen 2, Martyn T Smith 9. In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. J Public Health Res. 2019 Sep 5;8(2):1550. doi: 10.4081/jphr.2019.1550. PMID: 31572695 PMCID: PMC6747021 DOI: 10.4081/jphr.2019.1550

Westergaard, K., Endrestøl, A., Hanssen, O., Often, A., Åström, J., Fossøy, F., Jacobsen, R., Kyrkjeeide, M.& Brandsegg, H.2019. Fremmede arter – spredningsveien import av planteprodukter. Basisovervåking og metodeutvikling 2017–2018. NINA Rapport nr 1557. Norsk institutt for naturforskning(NINA), Trondheim.

Taugbøl, A., Dervo, B., Brandsegg, H.& Fossøy, F.2019. Analyser av miljø-DNA og strykeprøver for overvåking av soppen Batrachochytrium dendrobatidis (Bd) i Akershus. NINA Rapport nr 1660. Norsk institutt for naturforskning(NINA), Trondheim.

Fossøy, F., Thaulow, J., d'Auriac, M., Brandsegg, H., Sivertsgård, R., Mo, T., Sandlund, O.& Hesthagen, T.2019. Bruk av miljø-DNA som supplerende verktøy for overvåkning og kartlegging av fremmed ferskvannsfisk. NINA Rapport nr 1586. Norsk institutt for naturforskning(NINA), Trondheim.

Jacobsen, R., Åström, J., Endrestøl, A., Blaalid, R., Fossøy, F., Often, A.& Sandercock, B.2019. Tidlig oppdagelse og varsling av nye fremmede arter i Norge. System for overvåking av fremmede terrestriske karplanter og insekter. NINA Rapport nr 1569. Norsk institutt for naturforskning(NINA), Trondheim.

Skottene E, Tarrant AM, Olsen AJ, Altin D, Østensen MA, Hansen BH, Choquet M, Jenssen BM, Olsen RE. The β-oxidation pathway is downregulated during diapause termination in Calanus copepods. Sci Rep. 2019 Nov 13;9(1):16686. doi: 10.1038/s41598-019-53032-5.

Skottene E, Tarrant AM, Olsen AJ, Altin D, Hansen BH, Choquet M, Olsen RE, Jenssen BM. A Crude Awakening: Effects of Crude Oil on Lipid Metabolism in Calanoid Copepods Terminating Diapause. Biol Bull. 2019 Oct;237(2):90-110. doi: 10.1086/705234. Epub 2019 Oct 4.

Sun Z, Majaneva M, Sokolova E, Rauch S, Meland S, Ekrem T. DNA metabarcoding adds valuable information for management of biodiversity in roadside stormwater ponds. Ecol Evol. 2019 Aug 2;9(17):9712-9722. doi: 10.1002/ece3.5503. eCollection 2019 Sep.

Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F. Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. Oncogene. 2019 Aug;38(35):6301-6318. doi: 10.1038/s41388-019-0879-2. Epub 2019 Jul 16.

Yousefi, N.aEmail Author, Mikulášková, E.b, Stenøien, H.K.a, Flatberg, K.I.a, Košuthová, A.b,c, Hájek, M.b, Hassel, K. Genetic and morphological variation in the circumpolar distribution range of Sphagnum warnstorfii: Indications of vicariant divergence in a common peatmoss. Botanical Journal of the Linnean Society. Volume 189, Issue 4, 27 March 2019, Pages 408-423.

Vange P, Bruland T, Munkvold B , Røyset ES, Gleave M, Bakke I. Subtle Protective Roles of Clusterin in Gastric Metaplasia After Acute Oxyntic Atrophy. Cell Mol Gastroenterol Hepatol. 2019;7(1):246-250.e1. doi: 10.1016/j.jcmgh.2018.09.013. Epub 2018 Sep 22.

Foote AD , Martin MD , Louis M, Pacheco G , Robertson KM , Sinding MS, Amaral AR, Baird RW, Baker CS, Ballance L, Barlow J, Brownlow A, Collins T, Constantine R, Dabin W, Dalla Rosa L, Davison NJ, Durban JW, Esteban R, Ferguson SH, Gerrodette T, Guinet C, Hanson MB, Hoggard W, Matthews CJD, Samarra FIP, de Stephanis R, Tavares SB, Tixier P, Totterdell JA, Wade P, Excoffier L, Gilbert MTP, Wolf JBW, Morin PA. Killer whale genomes reveal a complex history of recurrent admixture and vicariance. Mol Ecol. 2019 Jul;28(14):3427-3444. doi: 10.1111/mec.15099. Epub 2019 May 27.

Gjevestad GO, Holven KB, Rundblad A, Flatberg A, Myhrstad M, Karlsen K, Mutt SJ, Herzig KH, Ottestad I, Ulven SM. Increased protein intake affects pro-opiomelanocortin (POMC) processing, immune function and IGF signaling in peripheral blood mononuclear cells of home-dwelling old subjects using a genome-wide gene expression approach. Genes Nutr. 2019 Nov 28;14:32. doi: 10.1186/s12263-019-0654-6. eCollection 2019.

Rounge TB, Lauritzen M, Erlandsen SE, Langseth H, Holmen OL, Gislefoss RE. Ultralow amounts of DNA from long-term archived serum samples produce quality genotypes. Eur J Hum Genet. 2019 Nov 12. doi: 10.1038/s41431-019-0543-x.

Hanna Maja Tunset, Astrid Jullumstrø Feuerherm, Linn-Karina Myrland Selvik, Berit Johansen and Siver Andreas Moestue. Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells Int. J. Mol. Sci. 2019, 20(19), 4800; https://doi.org/10.3390/ijms20194800

Thorsvik S, van Beelen Granlund A, Svendsen TD, Bakke I, Røyset ES, Flo TH, Damås JK, Østvik AE, Bruland T, Sandvik AK. Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. J Pathol. 2019 Jul;248(3):316-325. doi: 10.1002/path.5258.

Olaisen M, Spigset O, Flatberg A, Granlund AVB, Brede WR, Albrektsen G, Røyset ES, Gilde B, Sandvik AK, Martinsen TC, Fossmark R. Mucosal 5-aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis. Aliment Pharmacol Ther. 2019 May;49(10):1301-1313. doi: 10.1111/apt.15227.

Koch E, Finne K, Eikrem Ø, Landolt L, Beisland C, Leh S, Delaleu N, Granly M, Vikse BE, Osman T, Scherer A, Marti HP. Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms. Am J Physiol Renal Physiol. 2019 May 1;316(5):F1053-F1067. doi: 10.1152/ajprenal.00424.2018.

Moreira JBN, Wohlwend M, Fenk S, Åmellem I, Flatberg A, Kraljevic J, Marinovic J, Ljubkovic M, Bjørkøy G, Wisløff U. Exercise Reveals Proline Dehydrogenase as a Potential Target in Heart Failure. Prog Cardiovasc Dis. 2019 Mar - Apr;62(2):193-202. doi: 10.1016/j.pcad.2019.03.002.

 

2018

Engelsdorf T, Gigli-Bisceglia N, Veerabagu M, McKenna JF, Vaahtera L, Augstein F, Van der Does D, Zipfel C, Hamann T. The plant cell wall integrity maintenance and immune signaling systems cooperate to control stress responses in Arabidopsis thaliana. Sci Signal. 2018 Jun 26;11(536). pii: eaao3070. doi: 10.1126/scisignal.aao3070.

Andersen MK, Rise K, Giskeødegård GF, Richardsen E, Bertilsson H, Størkersen Ø, Bathen TF, Rye M, Tessem MB. Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma. Sci Rep. 2018 Sep 24;8(1):14269. doi: 10.1038/s41598-018-32549-1.

Lund E, Nakamura A, Snapkov I, Thalabard JC, Olsen KS, Holden L, Holden M. Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients.Clin Epidemiol. 2018 Aug 6;10:931-940. doi: 10.2147/CLEP.S163208.

Samdal H, Sandmoe MA, Olsen LC, Jarallah EAH, Høiem TS, Schønberg SA, Pettersen CHH. Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells.FEBS J. 2018 Jul;285(13):2446-2467. doi: 10.1111/febs.14488.

Caroline Krogh Søgaard, Augun Blindheim,Lisa M. Røst, Voin Petrović, Anala Nepal, Siri Bachke, Nina-Beate Liabakk, Odrun A. Gederaas, Trond Viset, Carl-Jørgen Arum, Per Bruheim, and Marit Otterlei. “Two hits - one stone”; increased efficacy of cisplatin-based therapies by targeting PCNA’s role in both DNA repair and cellular signaling. Oncotarget. 2018 Aug 21; 9(65): 32448–32465.

Caroline K. Søgaard, Siver A. Moestue, Morten B. Rye, Jana Kim, Anala Nepal, Nina-Beate Liabakk, Siri Bachke, Tone F. Bathen, Marit Otterlei, and Deborah K. Hill. APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. Oncotarget. 2018 Feb 20; 9(14): 11752–11766.

Nora Gigli-Bisceglia, Timo Engelsdorf, Miroslav Strnad, Lauri Vaahtera, Ghazanfar Abbas Khan, Amel Yamoune, Leila Alipanah, Ondřej Novák, Staffan Persson, Jan Hejatko, Thorsten Hamann. Cell wall integrity modulates Arabidopsis thaliana cell cycle gene expression in a cytokinin- and nitrate reductase-dependent manner. Development 2018 145: dev166678 doi: 10.1242/dev.166678 Published 2 October 2018

Thorsvik S, Bakke I, van Beelen Granlund A, Røyset ES, Damås JK, Østvik AE, Sandvik AK. Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell Tissue Res. 2018 Nov;374(2):339-348. doi: 10.1007/s00441-018-2860-8.

Dybos SA, Flatberg A, Halgunset J, Viset T, Rolfseng T, Kvam S, Skogseth H. Increased levels of serum mi-148a-3p are associated with prostate cancer. APMIS. 2018 Sep;126(9):722-731. doi: 10.1111/apm.12880.

Kiboub FZ, Møllerløkken A, Hjelde A, Flatberg A, Loennechen Ø, Eftedal I. Blood Gene Expression and Vascular Function Biomarkers in Professional Saturation Diving.Front Physiol. 2018 Jul 16;9:937. doi: 10.3389/fphys.2018.00937.

Eikrem Ø, Walther TC, Flatberg A, Beisvag V, Strauss P, Farstad M, Beisland C, Koch E, Mueller TF, Marti HP. Fine needle aspirates of kidneys: a promising tool for RNA sequencing in native and transplanted kidneys. BMC Nephrol. 2018 Sep 5;19(1):221. doi: 10.1186/s12882-018-1012-4.

Strauss P, Marti HP, Beisland C, Scherer A, Lysne V, Leh S, Flatberg A, Koch E, Beisvag V, Landolt L, Skogstrand T, Eikrem Ø. Expanding the Utilization of Formalin-Fixed, Paraffin-Embedded Archives: Feasibility of miR-Seq for Disease Exploration and Biomarker Development from Biopsies with Clear Cell Renal Cell Carcinoma. Int J Mol Sci. 2018 Mar 10;19(3). pii: E803. doi: 10.3390/ijms19030803.

Aas CG, Drabløs F, Haugum K, Afset JE. Comparative Transcriptome Profiling Reveals a Potential Role of Type VI Secretion System and Fimbriae in Virulence of Non-O157 Shiga Toxin-Producing Escherichia coli. Front Microbiol. 2018 Jun 29;9:1416. doi: 10.3389/fmicb.2018.01416.

 

2017

Hansen MF, Johansen J, Sylvander AE, Bjørnevoll I, Talseth-Palmer BA, Lavik LAS, Xavier A, Engebretsen LF, Scott RJ, Drabløs F, Sjursen W. Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome. Clin Genet. 2017 Oct;92(4):405-414. doi: 10.1111/cge.12994. Epub 2017 Mar 22.

Landolt L, Eikrem Ø, Strauss P, Scherer A, Lovett DH, Beisland C, Finne K, Osman T, Ibrahim MM, Gausdal G, Ahmed L, Lorens JB, Thiery JP, Tan TZ, Sekulic M, Marti HP. Clear Cell Renal Cell Carcinoma is linked to Epithelial-to-Mesenchymal Transition and to Fibrosis. Physiol Rep. 2017 Jun;5(11). pii: e13305. doi: 10.14814/phy2.13305.

Sandsmark E, Andersen MK, Bofin AM, Bertilsson H, Drabløs F, Bathen TF, Rye MB, Tessem MB. SFRP4 gene expression is increased in aggressive prostate cancer. Sci Rep. 2017 Oct 27;7(1):14276. doi: 10.1038/s41598-017-14622-3.

Sandsmark E, Hansen AF, Selnæs KM, Bertilsson H, Bofin AM, Wright AJ, Viset T, Richardsen E, Drabløs F, Bathen TF, Tessem MB, Rye MB. A novel non-canonical Wnt signature for prostate cancer aggressiveness. Oncotarget. 2017 Feb 7;8(6):9572-9586. doi: 10.18632/oncotarget.14161.

Silva CNS1, McFarlane SE, Hagen IJ, Rönnegård L, Billing AM, Kvalnes T, Kemppainen P, Rønning B, Ringsby TH, Sæther BE, Qvarnström A, Ellegren H, Jensen H, Husby A1. Insights into the genetic architecture of morphological traits in two passerine bird species. Heredity (Edinb). 2017 Sep;119(3):197-205. doi: 10.1038/hdy.2017.29.

Yousefi N, Hassel K, Flatberg KI, Kemppainen P, Trucchi E, Shaw AJ, Kyrkjeeide MO, Szövényi P, Stenøien HK. Divergent evolution and niche differentiation within the common peatmoss Sphagnum magellanicum.Am J Bot. 2017 Jul 28. doi: 10.3732/ajb.1700163.

Mjelle R, Sellæg K, Sætrom P, Thommesen L, Sjursen W, Hofsli E. Identification of metastasis-associated microRNAs in serum from rectal cancer patients. Oncotarget. 2017 Sep 30;8(52):90077-90089. doi: 10.18632/oncotarget.21412.

Pål Vange, Torunn Bruland, Berit Doseth, Reidar Fossmark, Mirta M. L. Sousa, Vidar Beisvag, Øystein Sørdal, Gunnar Qvigstad, Helge L. Waldum, Arne K. Sandvik, Ingunn Bakke. The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PloS one 12 (9)September 13, 2017

Skogholt AH, Ryeng E, Erlandsen SE, Skorpen F, Schønberg SA, Sætrom P. Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Res Notes. 2017 Mar 23;10(1):136.

Even Holth Rustad, Eivind Coward, Emilie R Skytøen, Kristine Misund, Toril Holien, Therese Standal, Magne Børset, Vidar Beisvag, Ola Myklebost, Leonardo A Meza-Zepeda, Hong Yan Dai, Anders Sundan, Anders Waage. Monitoring of multiple myeloma by quantification of recurrent mutations in serum. Haematologica, 4/6 2017.

Olsen LC, O'Reilly KC, Liabakk NB, Witter MP, Sætrom P. MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Struct Funct. 2017 Mar 4

Webb TR, Holmen OL, Hveem K et al. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol. 2017 Feb 21;69(7):823-836.

Marouli E, Holmen OL, Hveem K et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017 Feb 9;542(7640):186-190.

 

2016

Kristin M Aasarød, Masoud Ramezanzadehkoldeh, Maziar Shabestari, Mats P Mosti, Astrid K Stunes, Janne E Reseland, Vidar Beisvag, Erik Fink Eriksen, Arne K Sandvik, Reinhold G Erben, Christiane Schüler, Malcolm Boyce, Bjørn H Skallerud, Unni Syversen, Reidar Fossmark. Skeletal effects of a gastrin receptor antagonist in H+/K+ ATPase beta subunit KO mice. Journal of Endocrinology 230 (2), 251-262, 2016.

Eikrem OS, Strauss P, Beisland C, Scherer A, Landolt L, Flatberg A, Leh S, Beisvag V, Skogstrand T, Hjelle K, Shresta A, Marti HP. Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scand J Urol. 2016 Dec;50(6):452-462.

Zayats T, Holmen OL et al. Exome chip analyses in adult attention deficit hyperactivity disorder. Transl Psychiatry. 2016 Oct 18;6(10)

Ehret GB, Kvaløy K, Holmen OL, Hveem K et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 Oct;48(10):1171-84

Surendran P, Holmen OL, Hveem K et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet. 2016 Oct;48(10):1151-61.

Eftedal I, Flatberg A, Drvis I, Dujic Z. Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles. Physiol Genomics. 2016 Nov 1;48(11):795-802

Landolt L, Marti HP, Beisland C, Flatberg A, Eikrem OS. RNA extraction for RNA sequencing of archival renal tissues. Scand J Clin Lab Invest. 2016 Sep;76(5):426-34.

Bhandari S, Bakke I, Kumar J, Beisvag V, Sandvik AK, Thommesen L, Varro A, Nørsett KG. Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. Biochem Biophys Res Commun. 2016 Jun 17;475(1):119-24.

Fossmark R, Rao S, Mjønes P, Munkvold B, Flatberg A, Varro A, Thommesen L, Nørsett KG. PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa. Peptides. 2016 May;79:83-94.

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators., Stitziel NO, Holmen OL, Hveem K et al. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med. 2016 Mar 24;374(12):1134-44

Eikrem O, Beisland C, Hjelle K, Flatberg A, Scherer A, Landolt L, Skogstrand T, Leh S, Beisvag V, Marti HP. Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development. PLoS One. 2016 Feb 22;11(2).

 

2015

Tang CS, Holmen OL, Hveem K et al. Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Nat Commun. 2015 Dec 22;6.

Simpson MR, Brede G, Johansen J, Johnsen R, Storrø O, Sætrom P, Øien T. Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring. PLoS One. 2015 Dec 14;10(12)

Gaulton KJ, Holmen OL, Hveem K et al.Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet. 2015 Dec;47(12)

Pettersen K, Monsen VT, Hakvåg Pettersen CH, Overland HB, Pettersen G, Samdal H, Tesfahun AN, Lundemo AG, Bjørkøy G, Schønberg S.DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2015 Nov 14

Skovdahl HK, Granlund Av, Østvik AE, Bruland T, Bakke I, Torp SH, Damås JK, Sandvik AK. Expression of CCL20 and Its Corresponding Receptor CCR6 I Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells. PLoS One. 2015 Nov 4;10(11)

Winkler TW, Holmen OL, Hveem K et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct 1;11(10)

Johansson I, Monsen VT, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, Schønberg S, Bjørkøy G. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy. 2015 Sep 2;11(9):1636-51.

Vange P, Bruland T, Beisvag V, Erlandsen SE, Flatberg A, Doseth B, Sandvik AK, Bakke I.Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker over-expressed in cancer. J Pathol. 2015 Jul 16

Brenna Ø, Bruland T, Furnes MW, Granlund AV, Drozdov I, Emgård J, Brønstad G, Kidd M, Sandvik AK, Gustafsson BI.The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease. Scand J Gastroenterol. 2015 May 15:1-12.

Hansen MF, Johansen J, Bjørnevoll I, Sylvander AE, Steinsbekk KS, Sætrom P, Sandvik AK, Drabløs F, Sjursen W. A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Fam Cancer. 2015 Apr 10.

Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A. BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer J. 2015 Mar 20;5:e299.

Dumeaux V, Ursini-Siegel J, Flatberg A, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Lund E. Peripheral blood cells inform on the presence of breast cancer: a population-based case-control study. Int J Cancer. 2015 Feb 1;136(3):656-67.

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH,et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12;518(7538):197-206.

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12;518(7538):187-96.

 

2014

Ostvik AE, Granlund Av, Gustafsson BI, Torp SH, Espevik T, Mollnes TE, Damås JK, Sandvik AK. Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflamm Bowel Dis. 2014 Jun;20(6):995-1003. doi: 10.1097/MIB.0000000000000035.

Wood AR, Esko T, Yang J, Vedantam S, Pers TH, et al.Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014 Nov;46(11):1173-86.

Zhao CM, Kodama Y, Flatberg A, Beisvag V, Kulseng B, Sandvik AK, Rehfeld JF, Chen D. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regul Pept. 2014 Jun-Aug;192-193:35-44.

Zhao CM, Hayakawa Y, Kodama Y, Muthupalani S, Westphalen CB, Andersen GT, Flatberg A, Johannessen H, Friedman RA, Renz BW, Sandvik AK, Beisvag V, Tomita H, Hara A, Quante M, Li Z, Gershon MD, Kaneko K, Fox JG, Wang TC, Chen D. Denervation suppresses gastric tumorigenesis. Sci Transl Med. 2014 Aug 20;6(250.

O'Reilly KC, Flatberg A, Islam S, Olsen LC, Kruge IU, Witter MP. Identification of dorsal-ventral hippocampal differentiation in neonatal rats. Brain Struct Funct. 2014 Jul 11.

Holmen OL, Zhang H, Fan Y, Hovelson DH, Schmidt EM, Zhou W, Guo Y, Zhang J, Langhammer A, Løchen ML, Ganesh SK, Vatten L, Skorpen F, Dalen H, Zhang J, Pennathur S, Chen J, Platou C, Mathiesen EB, Wilsgaard T, Njølstad I, Boehnke M, Chen YE, Abecasis GR, Hveem K, Willer CJ. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat Genet. 2014 Apr;46(4):345-51.

Razick S, Mocnik R, Thomas LF, Ryeng E, Drabløs F, Sætrom P. The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database (Oxford). 2014 Mar 28;2014

Myhrstad MC, Ulven SM, Günther CC, Ottestad I, Holden M, Ryeng E, Borge GI, Kohler A, Brønner KW, Thoresen M, Holven KB. Fish oil supplementation induces expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. J Intern Med. 2014 Nov;276(5):498-511.

Agdestein A, Jones A, Flatberg A, Johansen TB, Heffernan IA, Djønne B, Bosco A, Olsen I1. Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection. BMC Genomics. 2014 Jan 23;15:58.

 

2013

Hagen IJ, Billing AM, Rønning B, Pedersen SA, Pärn H, Slate J, Jensen H. The easy road to genome-wide medium density SNP screening in a non-model species: development and application of a 10 K SNP-chip for the house sparrow (Passer domesticus). Mol Ecol Resour. 2013 May;13(3):429-39. doi: 10.1111/1755-0998.12088.

Granlund Av, Flatberg A, Østvik AE, Drozdov I, Gustafsson BI, Kidd M, Beisvag V, Torp SH, Waldum HL, Martinsen TC, Damås JK, Espevik T, Sandvik AK. Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis. PLoS One. 2013;8(2):e56818.

Ostvik AE, Granlund AV, Bugge M, Nilsen NJ, Torp SH, Waldum HL, Damås JK, Espevik T, Sandvik AK. Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation. Inflamm Bowel Dis. 2013 Feb;19(2):265-74.

Misund K, Selvik LK, Rao S, Nørsett K, Bakke I, Sandvik AK, Lægreid A, Bruland T, Prestvik WS, Thommesen L. NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells. PLoS One. 2013 Sep 27;8(9):e76234.

Brenna Ø, Furnes MW, Drozdov I, van Beelen Granlund A, Flatberg A, Sandvik AK, Zwiggelaar RT, Mårvik R, Nordrum IS, Kidd M, Gustafsson BI. Relevance of TNBS-colitis in rats: a methodological study with endoscopic, histologic and Transcriptomic characterization and correlation to IBD. PLoS One. 2013;8(1):e54543.

Eftedal I, Ljubkovic M, Flatberg A, Jørgensen A, Brubakk AO, Dujic Z. Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced divers. Physiol Genomics. 2013 Oct 16;45(20):965-72.

Østvik AE, Granlund AV, Torp SH, Flatberg A, Beisvåg V, Waldum HL, Flo TH, Espevik T, Damås JK, Sandvik AK. Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clin Exp Immunol. 2013 Sep;173(3):502-11.

Brattbakk HR, Arbo I, Aagaard S, Lindseth I, de Soysa AK, Langaas M, Kulseng B, Lindberg F, Johansen B. Balanced caloric macronutrient composition downregulates immunological gene expression in human blood cells-adipose tissue diverges. OMICS. 2013 Jan;17(1):41-52.

Berg K, Langaas M, Ericsson M, Pleym H, Basu S, Nordrum IS, Vitale N, Haaverstad R. Acetylsalicylic acid treatment until surgery reduces oxidative stress and inflammation in patients undergoing coronary artery bypass grafting. Eur J Cardiothorac Surg. 2013 Jun;43(6):1154-63.

Selvik LK, Fjeldbo CS, Flatberg A, Steigedal TS, Misund K, Anderssen E, Doseth B, Langaas M, Tripathi S, Beisvag V, Lægreid A, Thommesen L, Bruland T. The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics. 2013 Jun 28;14:429.

 

2012

Røe, Oluf Dimitri; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore; Erlandsen, Sten Even; Dobra, Katalin; Sundstrøm, Stein Harald.  Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma. PLoS ONE 2012 ;Volume 7.(8)

Reinertsen, Tove; Halgunset, Jostein; Viset, Trond; Flatberg, Arnar; Haugsmoen, Linn Lervik; Skogseth, Haakon. Gene expressional changes in prostate fibroblasts from cancerous tissue. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS) 2012 ;Volume 120.(7) p. 558-571

Eftedal, Ingrid; Jørgensen, Arve; Røsbjørgen, Ragnhild; Flatberg, Arnar; Brubakk, Alf O. Early genetic responses in rat vascular tissue after simulated diving. Physiological Genomics 2012 ;Volume 44.(24) p. 1201-1207

Bertilsson, Helena; Tessem, May-Britt; Flatberg, Arnar; Viset, Trond; Gribbestad, Ingrid S; Angelsen, Anders; Halgunset, Jostein. Changes in Gene Transcription Underlying the Aberrant Citrate and Choline Metabolism in Human Prostate Cancer Samples. Clinical Cancer Research 2012 ;Volume 18.(12) p. 3261-3269

Fjeldbo CS, Bakke I, Erlandsen SE, Holmseth J, Lægreid A, Sandvik AK, Thommesen L, Bruland T. Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. Am J Physiol Gastrointest Liver Physiol. 2012 Jan 1;302(1):G21-33.

 

2011

Granlund AB, Beisvag V, Torp SH, Flatberg A, Kleveland PM, Ostvik AE, Waldum HL, Sandvik AK. Activation of REG family proteins in colitis. Scand J Gastroenterol. 2011 Nov;46(11):1316-23.

Maple J, Winge P, Tveitaskog AE, Gargano D, Bones AM, Møller SG.Genome-wide gene expression profiles in response to plastid division perturbations. Planta. 2011 Nov;234(5):1055-63.

Lundemo AG, Pettersen CH, Berge K, Berge RK, Schønberg SA.Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress. Lipids Health Dis. 2011 Oct 25;10:190.

Lalvetti S, Faegri K, Ghelardi E, Kolstø AB, Senesi S. Global gene expression profile for swarming Bacillus cereus bacteria. Appl Environ Microbiol. 2011 Aug;77(15):5149-56. Epub 2011 Jun 3.

Kusnierczyk A, Tran DH, Winge P, Jørstad TS, Reese JC, Troczynska J, Bones AM. Testing the importance of jasmonate signalling in induction of plant defences upon cabbage aphid (Brevicoryne brassicae) attack. BMC Genomics. 2011 Aug 19;12:423.

Doseth B, Visnes T, Wallenius A, Ericsson I, Sarno A, Pettersen HS, Flatberg A, Catterall T, Slupphaug G, Krokan HE, Kavli B. Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse. J Biol Chem. 2011 May 13;286(19):16669-80.

Jørgensen KM, Hjelle SM, Øye OK, Puntervoll P, Reikvam H, Skavland J, Anderssen E, Bruserud Ø, Gjertsen BT. Untangling the intracellular signalling network in cancer--a strategy for data integration in acute myeloid leukaemia. J Proteomics. 2011 Mar 1;74(3):269-81.

Vidar Beisvag, Audrey Kauffmann, James Malone, Carole Foy, Marc Salit, Heinz Schimmel5, Erik Bongcam-Rudloff, Ulf Landegren, Helen Parkinson, Wolfgang Huber, Alvis Brazma, Arne K. Sandvik and Martin Kuiper. Contributions of the EMERALD project to assessing and improving microarray data quality. BioTechniques 2011 Jan 50:27-31

 

2010

Slagsvold JE, Pettersen CH, Størvold GL, Follestad T, Krokan HE, Schønberg SA. DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. Nutr Cancer. 2010;62(5):611-21.

Hanne K. Skjeldam, Henok Kassahun, Øyvind Fensgård, Tanima SenGupta, Eshrat Babaie, Jessica M. Lindvall, Katarzyna Arczewska, Hilde Nilsen Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents DNA Repair (Amst). 2010 Aug 5;9(8):861-70.

Huuse EM, Jensen LR, Goa PE, Lundgren S, Anderssen E, Bofin A, Gribbestad IS, Bathen TF. Monitoring the Effect of Docetaxel Treatment in MCF7 Xenografts Using Multimodal In Vivo and Ex Vivo Magnetic Resonance Methods, Histopathology, and Gene Expression. Transl Oncol. 2010 Aug 1;3(4):252-63.

Arum CJ, Anderssen E, Viset T, Kodama Y, Lundgren S, Chen D, Zhao CM. Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer. Neoplasia. 2010 Jun;12(6):434-42.

Arum CJ, Kodama Y, Rolim N, Widerøe M, Anderssen E, Viset T, Otterlei M, Lundgren S, Chen D, Zhao CM. A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World J Urol. 2010 Aug;28(4):479-85. Epub 2010 Apr 8.

Arum CJ, Anderssen E, Tømmerås K, Lundgren S, Chen D, Zhao CM. Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology. 2010 Mar;75(3):742-9. Epub 2009 Aug 3.

Fensgård Ø, Kassahun H, Bombik I, Rognes T, Lindvall JM, Nilsen H. A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways. Aging (Albany NY). 2010 Mar 31;2(3):133-59.

Bertilsson H, Angelsen A, Viset T, Anderssen E, Halgunset J. RNA quality in fresh frozen prostate tissue from patients operated with radical prostatectomy. Scand J Clin Lab Invest. 2010 Feb;70(1):45-53.

Røe OD, Anderssen E, Sandeck H, Christensen T, Larsson E, Lundgren S. Malignant pleural mesothelioma: Genome-wide expression patterns reflecting general resistance mechanisms and a proposal of novel targets. Lung Cancer. 2010 Jan;67(1):57-68.

Follestad T, Jørstad TS, Erlandsen SE, Sandvik AK, Bones AM, Langaas M.  A Bayesian hierarchical model for quantitative real-time PCR data. Stat Appl Genet Mol Biol., 2010;9(1)

Bertilsson H, Angelsen A, Viset T, Anderssen E, Halgunset J. RNA quality in fresh frozen prostate tissue from patients operated with radical prostatectomy. Scand J Clin Lab Invest2010 Feb;70(1):45-53.

Kissen R, Winge P, Tran DH, Jørstad TS, Størseth TR, Christensen T, Bones AM. Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. BMC Genomics2010 Mar 22;11:190.

 

2009

Beisvag V, Kemi OJ, Arbo I, Loennechen JP, Wisløff U, Langaas M, Sandvik AK, Ellingsen Ø. Pathological and physiological hypertrophies are regulated by distinct gene programs. Eur J Cardiovasc Prev Rehabil. 2009 Dec;16(6):690-7.

Røe OD, Anderssen E, Helge E, Pettersen CH, Olsen KS, Sandeck H, Haaverstad R, Lundgren S, Larsson E. Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. PLoS One. 2009 Aug. 7 ;4(8):e6554.

Gro L Størvold, Karianne G Fleten, Cathrine G Olsen, Turid Follestad, Hans E Krokan and Svanhild A Schønberg. Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells”. Lipids 2009 Aug. 44 (8), 673-683.
Jens E Slagsvold, Caroline H Hakvåg Pettersen, Turid Follestad, Hans E Krokan and Svanhild A Schønberg. The antiproliferative effect of eicosapentaenoic acid is caused by alterations in calcium homeostasis and activation of the unfolded protein response”. Lipids 2009 Feb. 44 (2), 103-113.

Sehic A, Khuu C, Risnes S, Osmundsen H. Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104.

 

2008

Hofsli E, Wheeler TE, Langaas M, Laegreid A, Thommesen L. Identification of novel neuroendocrine-specific tumour genes. Br J Cancer. 2008 Oct 21;99(8):1330-9.

Bye A, Høydal MA, Catalucci D, Langaas M, Kemi OJ, Beisvag V, Koch LG, Britton SL, Ellingsen Ø, Wisløff U. Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiol Genomics. 2008 Nov. 12;35(3):213-21.

Nilsen AJ, Landin MA, Haug KH, Fonnum F, Berger U, Osmundsen H. Comparative hepatic gene expression profiling of rats treated with 1H,1H,2H,2H-heptadecafluorodecan-1-ol or with pentadecafluorooctanoic acid. Physiol Genomics. 2008 Aug. 15;34(3):285-303.

Afset JE, Anderssen E, Bruant G, Harel J, Wieler L, Bergh K. Phylogenetic backgrounds and virulence profiles of atypical enteropathogenic Escherichia coli strains from a case-control study using multilocus sequence typing and DNA microarray analysis. J Clin Microbiol.; 2008 Jul. 46(7):2280-90.

Eide IP, Isaksen CV, Salvesen KA, Langaas M, Schønberg SA, Austgulen R. Decidual expression and maternal serum levels of heme oxygenase 1 are increased in pre-eclampsia. Acta Obstet Gynecol Scand. 2008 87(3):272-9.

Nørsett KG, Laegreid A, Kusnierczyk W, Langaas M, Ylving S, Fossmark R, Myhre S, Falkmer S, Waldum HL, Sandvik AK. Changes in gene expression of gastric mucosa during therapeutic acid inhibition. Eur J Gastroenterol Hepatol. 2008 Jul. 20(7):613-23.

Anja Bye, Mette Langaas, Morten A. Høydal, Ole Johan Kemi, Garrett Heinrich, Lauren G. Koch, Steven L. Britton, Sonia M. Najja, Øyvind Ellingsen and Ulrik Wisløff. Aerobic capacity-dependent differences in cardiac gene expression. Physiol Genomics. 2008 Mar. 14;33(1):100-9.

Pål A Olsvik, Kai K Lie, Eva Mykkeltvedt, Ole B Samuelsen, Kjell Petersen, Anne-Kristin Stavrum and Bjørn T Lunestad. “Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)”. BMC Pharmacology 2008 8:16

Caroline Hild Jakobsen, Gro Leite Størvold , Hilde Bremseth , Turid Follestad, Kristin Sand, Merete Mack, Karina Standahl Olsen, Anne Gøril Lundemo, Jens Gustav Iversen, Hans Einar Krokan and Svanhild Arentz Schønberg. “DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis“. Journal of Lipid Research 2008 Volume 49.

Christina Sæten Fjeldbo, Kristine Misund, Clara-Cecilie Günther, Mette Langaas, Tonje Strømmen Steigedal, Liv Thommesen, Astrid Lægreid and Torunn Bruland. “Functional studies on transfected cell microarray analysed by linear regression modeling” Nucleic Acids Research 2008 Sept 1–15

Rye, M.B., Færgestad, Martens, H., Wold, J.P. and Alsberg, B.K. "An improved pixel-based approach for analysing images in two-dimensional gel electrophoresis." Electrophoresis. 2008 Volume 29 Issue 6, No. 6, Pages 1382–1393.

Rye, M.B., Færgestad, and Alsberg, B.K. "A new method for assigning common spot boundaries for multiple gels in two-dimensional gel electrophoresis." Electrophoresis. 2008 Volume 29, Issue 6: No. 6 March 2008, Pages:1359-1368.

Rye, M.B., and Alsberg, B.K. "A multivariate spot filtering model for two-dimensional gel electrophoresis." Electrophoresis. Volume 29, Issue 6, Date: No. 6 March 2008, Pages: 1369-1381.

Juel IS, Solligård E, Tvedt KE, Skogvoll E, Jynge P, Beisvag V, Erlandsen SE, Sandvik AK, Aadahl P, Grønbech JE. Post-ischaemic restituted intestinal mucosa is more resistant to further ischaemia than normal mucosa in the pig. Scand J Clin Lab Invest. 2008;68(2):106-16.

 

2007

Kusnierczyk A, Winge P, Midelfart H, Armbruster WS, Rossiter JT, Bones AM. Transcriptional responses of Arabidopsis thaliana ecotypes with different glucosinolate profiles after attack by polyphagous Myzus persicae and oligophagous Brevicoryne brassicae. J Exp Bot. 2007;58(10):2537-2552.

Einset J, Nielsen E, Conolly EL, Bones AM, Sparstad T, Winge P, Zhu JK. Membrane-trafficking RabA4c involved in the effect of glycine betaine on recovery from chilling stress in Arabidopsis. Physiologia Plantarum, 2007; 130(4):511-518.

Einset J, Winge P and Bones AM. ROS Signaling Pathways in Chilling Stress. Plant Signaling & Behavior 2:5, 365-367, September/October 2007.
Irina P. Eide, Christina V. Isaksen, Kjell Å. Salvesen, Mette Langaas, Clara-Cecilie Günther, Ann-Charlotte Iversen and Rigmor Austgulen. “Fetal growth restriction is associated with reduced FasL expression by decidual cells”. Journal of Reproductive Immunology, Volume 74, Issues 1-2, June 2007.

Steigedal TS, Bruland T, Misund K, Thommesen L, Laegreid A. “Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression”. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1062-9. Epub 2006 Dec 21.

Osmundsen H, Landin MA, From SH, Kolltveit KM, Risnes S. “Changes in gene-expression during development of the murine molar tooth germ”. Arch Oral Biol. 2007;52:803-13.

Gidskehaug L, Anderssen E, Flatberg, A. and Alsberg BK "A framework for significance analysis of gene expression data using dimension reduction methods". BMC Bioinformatics. 2007 Sep 18;8:346.

Færgestad, E.M., Rye, M.B., Walczak, B., Gidskehaug, L., Grove, H., Jia, X., Hollung, K., Indahl, U.G., Westad, F., van der Berg, F. and Martens H. "Analysing two dimensional electrophoresis gel images on the level of pixels; a novel approach for analysing the proteome pattern." Proteomics. 2007 Oct;7(19):3450-61.

Bruland T, Anderssen E, Doseth B, Bergum H, Beisvag V, Laegreid A. “Optimization of cDNA microarrays procedures using criteria that do not rely on external standards”. BMC Genomics. 2007 Oct 18;8(1):377

Gidskehaug L, Anderssen E, Flatberg A, Alsberg BK. “A framework for significance analysis of gene expression data using dimension reduction methods”. BMC Bioinformatics. 2007 Sep 18;8(1):346

Juel IS, Solligård E, Tvedt KE, Skogvoll E, Jynge P, Beisvag V, Erlandsen SE, Sandvik AK, Aadahl P, Grønbech JE. “Post-ischaemic restituted intestinal mucosa is more resistant to further ischaemia than normal mucosa in the pig”. Scand J Clin Lab Invest. 2007 Sep 12;1-17

Erlandsen, S. E., Fykse, V., Waldum, H. L. and Sandvik, A. K., “Octreotide induces apoptosis in the oxyntic mucosa”, Mol Cell Endocrinol, 2007, 264:188-196.

 

2006

Beisvag, V., Junge, F. K., Bergum, H., Jolsum, L., Lydersen, S., Gunther, C. C., Ramampiaro, H., et al., “GeneTools - application for functional annotation and statistical hypothesis testing”, BMC Bioinformatics, 2006, 7:470.

Afset JE, Bruant G, Brousseau R, Harel J, Anderssen E, Bevanger L, Bergh K. “Identification of virulence genes linked with diarrhea due to atypical enteropathogenic Escherichia coli by DNA microarray analysis and PCR”. J Clin Microbiol. 2006 Oct;44(10):3703-11.

Murvoll KM, Skaare JU, Moe B, Anderssen E, Jenssen BM. “Spatial trends and associated biological responses of organochlorines and brominated flame retardants in hatchlings of north Atlantic kittiwakes (Rissa tridactyla)”.Environ Toxicol Chem. 2006 Jun;25(6):1648-56.

Beisvag, V., Lehre, P. K., Midelfart, H., Aass, H., Geiran, O., Sandvik, A. K., Laegreid, A., “Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data”, Eur J Heart Fail, 2006, 8(4):381-389.

Sandvik, A. K., Alsberg, B. K., Norsett, K. G., Yadetie, F., Waldum, H. L. and Laegreid, A., “Gene expression analysis and clinical diagnosis”, Clin Chim Acta, 2006, 363(1-2):157-164.

Gidskehaug L, Anderssen E, Alsberg B.K. "Cross model validated feature selection based on gene clusters" Chemometrics and intelligent laboratory systems 84 (1-2): 172-176, 2006

Myhre S, Tveit H, Mollestad T, Laegreid A. “Additional gene ontology structure for improved biological reasoning”. Bioinformatics. 2006 Aug 15;22(16):2020-7.

 

2005

Thommesen, L; Sæten C, Steigedal TS; Bruland T. 2005. Bruk av si RNA og RNAi cellearray i studier av molekylære mekanismer i mage-tarmsystemet. NBS-nytt Nr. 3/2005, side 6-11

Andersen S, Ericsson M, Dai HY, Pena-Diaz J, Slupphaug G, Nilsen H, Aarset H, Krokan HE. Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice. DNA Repair (Mast). 2005 Dec 8;4(12):1432-41.

Kristin G. Nørsett, Astrid Lægreid, Mette Langaas, Sara Worlund, Reidar Fossmark, Helge L. Waldum, Arne K Sandvik. Molecular characterisation of rat gastric mucosal response to potent acid inhibition. Physiol Genomic, 22:24-32, 2005.

 

2004

Fekadu Yadetie, Arne K Sandvik, Hallgeir Bergum, Kristin Nørsett, Astrid Laegreid. Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnol,June 10; 4(12),2004.

Flikka K, Yadetie F, Laegreid A, Jonassen I. XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. 2004 Aug 27;5:117.

 

2003

Kristin G. Nørsett, Astrid Lægreid, Herman Midelfart, Fekadu Yadetie, Sture Falkmer, Jon E. Grønbech, Helge L. Waldum, Jan Komorowski, Arne K. Sandvik. Gene expression based classification of gastric carcinoma. Cancer Lett, Jul 16;210(2):227-237, 2004.

Yadetie F, Laegreid A, Bakke I, Kusnierczyk W, Komorowski J, Waldum HL, Sandvik AK. Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate. Physiol Genomics. 2003 Sep 29;15(1):9-19.

Hvidsten TR, Laegreid A, Komorowski J. Learning rule-based models of biological process from gene expression time profiles using gene ontology. Bioinformatics. 2003 Jun 12;19(9):1116-23.

Alsberg B.K., Kirkhus L., Hagen R., Knudsen O., Tangstad T., Anderssen, E. "Zherlock: An open source data analysis software" SAR and QSAR in environmental research 14 (5-6): 349-360 OCT-DEC 2003

 

2002

Herman Midelfart, Jan Komorowski, Kristin G. Nørsett, Fekadu Yadetie, Arne K. Sandvik, Astrid Lægreid. Learning Rough Set Classifiers from Gene Expressions and Clinical Data. Fundamenta Informaticae, 53(2): 55-183, 2002.

 

2001

Arne K. Sandvik, Ole Støren, Kristin Nørsett, Astrid Lægreid, Anne Lise Børresen-Dale, Ola Myklebost. Måling av genaktivitet med DNA-mikromatriser Tidsskr Nor Lægeforen, 121: 1225-8, 2001.

Hvidsten TR, Komorowski J, Sandvik AK, Laegreid A. Predicting gene function from gene expressions and ontologies. Pac Symp Biocomput. 2001; 299-310.

Jenssen TK, Laegreid A, Komorowski J, Hovig E.  A literature network of human genes for high-throughput analysis of gene expression. Nat Genet. 2001 May;28(1):21-8.

Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Laegreid A, Sandvik AK. New knowledge derived from measurement of gene expression with the DNA microarray method. Tidsskr Nor Laegeforen. 2001 Apr 20;121(10):1229-32.

 

2000

Astrid Lægreid, Jan Komorowski, Arne K Sandvik, Eivind Hovig, Anne Forus, Birgitte Smith-Sørensen, Vidar Beisvåg, Bjørn Kristiansen, Kristin Nørsett, Vigdis Nygaard, Ole Støren, Ola Myklebost. DNA-mikroarray – vindu mot tusentals gen. NBS-nytt, 1:14-20, 2000.