NTNU Genome Editing
- NTNU Analysis, Design and Control of Microbial Systems
- NTNU Aquaculture Biotechnology
- NTNU Bioreactor Design and Operation
- NTNU Biopolymer Engineering
- NTNU Genome Editing
- NTNU Human Physiome
- NTNU Morphogenetic Engineering
- NTNU Phenomics Technology
- NTNU Tissue Engineering
- NTNU Synthetic Biology Engineering
- NTNU Therapeutic Targeting
- NTNU Responsible Research and Innovation
Finished project
(R) NTNU Genome Editing Blurb
NTNU Genome Editing
We are in the process of taking advantage of the current revolution in making targeted genome sequence changes.
Research activity
The capacity to introduce targeted genomic sequence changes in living cells and organisms has been revolutionised the last few years due to the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) technology. The CRISPR-Cas9 system enables fast and simple genome editing and NTNU is now building a research programme centred on exploitation of this extremely promising technology for research and future applications in industrial biotechnology, biomedicine, agriculture and aquaculture.
We are in particular focused on using the technology to address challenging problems associated with photosynthesis and nutrient responses of marine algae as well as lipid metabolism in Atlantic salmon. Our activities involve streamlining and developing methods, protocols and tools to facilitate more efficient and much more targeted and controllable genetic modifications. An efficient system for verification of edited gene loci, rearing, maintenance and phenotyping needed for making a generic and robust production line will also be established.
Considering the implications of this research, we want to contribute to a broad societal dialogue on the scientific, ethical and legal opportunities and consequences resulting from the use of this very potent genome editing technology.