course-details-portlet

BT8120

Prokaryote Molecular Biology and Synthetic Biology

Choose study year
Credits 7.5
Level Doctoral degree level
Course start Spring 2025
Duration 1 semester
Language of instruction English
Location Trondheim
Examination arrangement Work and Midterm

About

About the course

Course content

The course is offered every alternate year, next time spring 2025. The course will cover the following topics within basic procaryote molecular biology and physiology and synthetic biology:

  • Gene expression and regulation
  • Growth and Bioenergetics
  • Coordination and regulation of microbial metabolism
  • Cell differentiation
  • Cell communication and interactions
  • Secondary metabolism
  • Genetic circuits
  • Design, construction and expression of synthetic pathways
  • Genetic engineering techniques and tool boxes
  • Synthetic genomes and gene editing
  • Omics technologies (Genome and transcriptomics; Proteomics; Metabolomics, Fluxomics and lipid)

Learning outcome

The objective of the course is to provide an understanding of the physiology of the microbial cell and how it can be manipulated. Topics that are important for synthetic biology are emphasized. The second part focuses on the approaches and tools directly utilized in synthetic biology. After the course, the student will have acquired fundamental knowledge of procaryote molecular biology and physiology at an advanced level, and be able to analyze given problems and suggest how they may be solved. For the topics on genetic circuits and on -omics technologies, the aim is to provide the students with the understanding of what these approaches may contribute to a project.

Learning methods and activities

Topics in this course will be presented using new literature, lectures and discussions. The students will further be given a Paper to present as poster or orally. The course will be given in English and the exam will be given in English only. The lectures will be concentrated on 3 + 3 days (a total of 36 hours). In addition the students must expect 144 hours self study and 16 hours working on the presentation.

Further on evaluation

Group based work will be presented and counts 20 %. The final, individual written semester test 80 %. In case of few students the semester test may be changed to an oral test.

Specific conditions

Admission to a programme of study is required:
Biotechnology (MBIOT5)
Biotechnology (PHBIOT)

Course materials

Provided at the beginning of the course.

Credit reductions

Course code Reduction From
BT8105 7.5 sp Autumn 2018
This course has academic overlap with the course in the table above. If you take overlapping courses, you will receive a credit reduction in the course where you have the lowest grade. If the grades are the same, the reduction will be applied to the course completed most recently.

Subject areas

  • Biotechnology
  • Technological subjects

Contact information

Course coordinator

Lecturers

Department with academic responsibility

Department of Biotechnology and Food Science