Adsorption of macromolecules onto responsive surfaces - Monte Carlo simulations of coarse-grained biophysical systems
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Adsorption of macromolecules onto responsive surfaces
Adsorption of macromolecules onto responsive surfaces
– Monte Carlo simulations of coarse-grained biophysical systems
Protein and polymer adsorption onto lipid bilayers and monolayers is fundamentally interesting and has great importance in medicine, biology and technological applications such as biosensors, implants, food and pharmaceutical formulations.
Here we use a simple membrane model that includes lateral diffusion and/or vertical excursions out of the bilayer (protrusions) to study the influence of such parameters on the adsorption degree of macromolecules and the conformational behavior of polyelectrolytes with different characteristics.