Seminar: Measuring metabolism in the human brain
Measuring metabolism in the human brain: Translational challenges and opportunities
8th and 9th of April 2024 | St. Olavs Hospital - Trondheim University Hospital
For the first time, the K. G. Jebsens Centre for Alzheimer’s Disease (JCA), the Norwegian Center for Headache Research (NorHead) and the Norwegian 7T MR Center will host a two-day seminar in translational neurometabolism.
We are grateful to be joined by excellent speakers who are international experts in their fields. They will cover a range of topics, including:
- State-of-the art magnetic resonance spectroscopy of the human brain: 1H MRS, 31P MRS, 2H MRS, MRSI, DW-MRS, fMRS
- Using PET to study metabolism in the human brain
- 13C MRS and genetic tools to study brain metabolism in animals and neural cell culture
- Multi-cellular brain energy metabolism – the astrocyte-neuron lactate shuttle
- Neurometabolism in neurodegenerative diseases
- Neurometabolism in headache disorders
- Clinical applications of magnetic resonance spectroscopy
The seminar is open to everyone with a research or clinical interest in brain metabolism.
Programme
The seminar sessions will take place in 1902-bygget, room 02S21
Day one: April 8th
09:00-09:45
Introduction to the seminar. Principles of translational neurometabolism.
Axel Karl Gottfrid Nyman, Erling Tronvik, Johanna Vannesjö and Asgeir Kobro-Flatmoen
09:45-10:45
Introduction to magnetic resonance spectroscopy.
Presenter: Guglielmo Genovese
10:45-11:00
First abstract presentation
11:00-11:15
Break
11:15-13:00
The astrocyte-neuron lactate shuttle. Evidence from cell, animal and human studies.
Presenters: Luc Pellerin and Anne-Karine Bouzier-Sore
13:00-14:30
Lunch, Fred Kavli building
14:30-15:30
31P and 2H MRS to measure human brain metabolism
Presenter: Jeanine Prompers
15:30-15:45
Second abstract presentation
15:45-16:00
Break
16:00-17:00
Using PET to measure glucose and oxygen consumption in the human brain
Presenter: Manu Goyal
17:00-19:00
Social program/leisure time (TBA)
19:00
Dinner, To Rom og Kjøkken
Day Two: April 9th
09:00-10:00
Diffusion MRS: Cell-specific morphology and metabolism
Presenter: Itamar Ronen
10:00-11:00
Mitochondrial dysfunction in Parkinson’s disease
Presenter: Charalampos ”Haris” Tzoulis
10:45-11:00
Third abstract presentation
11:00-11:15
Break
11:15-12:15
MRS in migraine
Presenter: Samaira Younis
12:15-12:45
Clinical application of MRS
Presenter: Elise Sandsmark
13:00-14:30
Lunch, Fred Kavli building
14:30-14:45
Announcement and presentation of the prize for the best abstract presentation
Axel Nyman
14:45-16:00
Panel discussion
All invited speakers
16:00
Closing remarks
Axel Nyman
Luc Pellerin. Professor in cell biology
Université de Poitiers, France
Jeanine Prompers. Associate Professor Magnetic Resonance Metabolic Imaging.
7T MR group, UMC Uthrecht, the Netherlands
Manu Goyal, Associate Professor radiology and principal investigator in the Neuroimaging Labs Research Center for Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis, USA
Itamar Ronen. Chair in Medical Physics and Academic Director of CISC (Clinical Neuroscience), Brighton and Sussex Medical School, UK.
Anne-Karine Bouzier-Sore. PhD DR CNRS deputy director of the CRMSB at French National Centre for Scientific Research, University of Bordeaux, France
Charalampos “Haris” Tzoulis. Professor, Neurology and Neurodegeneration, UiB, Norway
Elise Sandsmark. MD, PhD Medical Doctor/Assoc. Professor at St. Olavs Hospital, Norway
Samaira Younis. MD, PhD Fellow, Human Migraine Research Unit, The Danish Headache Center, Rigshospitalet, Denmark
Guglielmo Genovese, PhD, Associate Professor, Department of Neuromedicine and Movement Science, NTNU, Norway.