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Språkvelger

Norsk

Axel Karl Gottfrid Nyman

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Axel Karl Gottfrid Nyman

Postdoctor
Department of Neuromedicine and Movement Science
Faculty of Medicine and Health Sciences

axel.nyman@ntnu.no
+4773598829 +4773598830 Nevrosenteret, Øya, Olav Kyrres gate 9
Publikasjonsliste
About Publications Outreach

About

Medical doctor and postdoctor at NTNU. I research Alzheimer's disease at the K.G. Jebsen center for Alzheimer's disease at NTNU. Resident at the Neurological Department, St Olavs Hospital.

Born:                          1989

Present position:        Postdoctor

 

Research interests

  • Experimental models of brain diseases
  • Image guided therapy of brain diseases
  • Treatment of brain diseases with melatonin
  • Neurodegeneration
  • Advanced MR-techniques in brain disorders

 

Current research projects

Advanced MR-techniques for discovery of biomarkers of early Alzheimer's disease

Metabolic changes in the brain during transient global amnesia

 

Previous research projects

Melatonin treatment of hypoxic-ischemic brain injury in neonatal rats

Lipid based nanoparticles for delivery of melatonin to the brain

Intermittent hyperoxia-hypoxia: Effect on cerebral vascularization, brain development and locomotor function in neonatal rats.

MRI of stem cell treatment of hypoxic-ischemic brain injury in neonatal and adult rats.

 

Education

2009-16: Medical student, NTNU, Trondheim, Norway

2011-15: Medical research student, NTNU, Trondheim, Norway

2016-21: PhD-student, NTNU, Trondheim, Norway

 

Publications

Competencies

  • Alzheimer's disease
  • MRI
  • Medical Imaging
  • Microdialysis
  • Neonatology
  • Neurometabolism
  • Neurosciences
  • Rat brain
  • Stem cell research
  • Translational medical research

Publications

  • Chronological
  • By category
  • See all publications in Cristin

2020

  • Molska, Alicja; Nyman, Axel Karl Gottfrid; Sofias, Alexandros Marios; Kristiansen, Kåre Andre; Hak, Sjoerd; Widerøe, Marius. (2020) In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations. European journal of pharmaceutics and biopharmaceutics
    Academic article

2019

  • Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Widerøe, Marius. (2019) Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats. PLOS ONE
    Academic article

2017

  • Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2017) Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy. PLOS ONE
    Academic article
  • Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Costa, Alex Ignatius; Barnett, Susan Carol; Sandvig, Axel; Håberg, Asta. (2017) Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat. Neurochemical Research
    Academic article

2013

  • Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon Sverre; Goa, Pål Erik. (2013) Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry. PLOS ONE
    Academic article

2012

  • Nyman, Axel Karl Gottfrid. (2012) In Bloom.
    Visual Arts

Journal publications

  • Molska, Alicja; Nyman, Axel Karl Gottfrid; Sofias, Alexandros Marios; Kristiansen, Kåre Andre; Hak, Sjoerd; Widerøe, Marius. (2020) In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations. European journal of pharmaceutics and biopharmaceutics
    Academic article
  • Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Widerøe, Marius. (2019) Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats. PLOS ONE
    Academic article
  • Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2017) Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy. PLOS ONE
    Academic article
  • Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Costa, Alex Ignatius; Barnett, Susan Carol; Sandvig, Axel; Håberg, Asta. (2017) Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat. Neurochemical Research
    Academic article
  • Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon Sverre; Goa, Pål Erik. (2013) Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry. PLOS ONE
    Academic article

Artistic productions

  • Nyman, Axel Karl Gottfrid. (2012) In Bloom.
    Visual Arts

Outreach

2024

  • Poster
    Johannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting 2024-01-15 - 2024-01-17
  • Poster
    Nyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. Trondheim fMRI group, MiDT national research centre, St. Olav's Hospital, and Department of Neuromedicine and Movement Science, NTNU The Aging Brain Conference , Union Hotel Geiranger 2024-06-12 - 2024-06-14
  • Academic lecture
    Nyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. ICBEM 15th International Conference on Brain Energy Metabolism (ICBEM) , Grand Hotel Union in Ljubljana, Slovenia 2024-09-17 - 2024-09-21

2023

  • Academic lecture
    Johannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik 2023-09-30 - 2023-09-30

2017

  • Lecture
    Molska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius. (2017) Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery. NRSN The 5th National PhD Conference in Neuroscience , Sommarøy 2017-09-20 - 2017-09-22

2015

  • Academic lecture
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) Early prognostic metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo proton MR spectroscopy. Norwegian Research School in Medical Imaging MedIm PhD conference , Oslo 2015-11-16 - 2015-11-17
  • Academic lecture
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) In-vivo MR metabolomics; A potential biomarker for neonatal hypoxic-ischemic brain injury?. Torstein Vik Cerebral Palsy masterclass , NTNU, Trondheim 2015-09-10 - 2015-09-10
  • Academic lecture
    Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. ASNTR 22nd Annual Conference of the American Society of Neural Therapy and Repair , Tampa, Florida 2015-04-30 - 2015-05-02
  • Poster
    Nyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Scandinavian Physiological Society Nordic Neuroscience 2015 , Trondheim 2015-06-10 - 2016-06-12

2014

  • Lecture
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) Effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. PAS/ASAP Pediatric Academic Societies and Asian Society For Pediatric Research , Vancouver 2014-05-03 - 2014-05-06
  • Poster
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: A longitudinal MR study. Johns Hopkins University School of Medicine 9th Hershey Conference on Developmental Brain Injury , Maryland 2014-06-03 - 2014-06-06
  • Lecture
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. Norsk Perinatalmedisinsk Forening (NPF) Perinatal asphyxia seminar , Trondheim 2014-11-10 - 2014-11-10
  • Lecture
    Berger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. Norsk Selskap for Magnetisk Resonans (NSMR) 13th National MR Meeting , Trondheim 2014-01-14 - 2014-01-15
  • Lecture
    Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse , Trondheim 2014-10-24 - 2014-10-26
  • Poster
    Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. NRSN Norwegian Research School in Neuroscience Annual Meeting , Stiklestad 2014-09-22 - 2014-09-24

2013

  • Interview
    Nyman, Axel Karl Gottfrid. (2013) Hjerneslaget på Stiklestad. Adresseavisen Adresseavisen [Newspaper] 2013-09-13
  • Poster
    Nyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. NRSN The 1st National PhD Conference in Neuroscience , Stiklestad 2013-09-10 - 2013-09-11
  • Academic lecture
    Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society 2013-05-04 - 2013-05-07
  • Poster
    Berger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. NRSN NRSN PhD Conference , Stiklestad 2013-09-10 - 2013-09-11
  • Lecture
    Berger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats:Preliminary results from a longitudinal MR study. MedIm PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03
  • Poster
    Nyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. Norwegian Research School in Medical Imaging 5th Norwegian PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03

2012

  • Poster
    Nyman, Axel Karl Gottfrid; Widerøe, Marius; Haraldseth, Olav. (2012) Longitudinal visualization of stem cell therapy in the hypoxic-ischemic premature brain using MRI. The 4th National PhD Conference in Medical Imaging 2012-11-28 - 2012-11-29

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