Inflammation is a host response that is triggered by noxious stimuli arising during infection and tissue injury. A controlled inflammatory response is needed to fight infections and to heal wounds, but can become detrimental if dysregulated. There is a growing understanding that some of the clinical manifestations are caused by common underlying inflammatory mechanisms instrumented by pattern recognition receptors.

Throughout the 1990s, researchers noticed that seemingly diverse diseases like atherosclerosis, type 2 diabetes, Alzheimer’s disease and some cancers, were characterized by an accumulation of immune cells at diseased sites. A prevailing hypothesis of today is that some of the clinical manifestations are caused by common underlying inflammatory mechanisms.

This conference will foster innovative research on molecular mechanisms and regulation of inflammation, and provide significant insight into common underlying processes of inflammatory disorders that can be translated to clinical settings.