GWAS
Genome-Wide Association Study (GWAS)
The impact on medical care from genome-wide association studies can be substantial, laying the groundwork for implementing personalized medicine, based on studies of genetic variation on a population level.
Great improvements have been made in the cost and efficiency of genome-wide scans and other innovative technologies, using such tools to provide patients with individualized information about their risk of developing certain diseases and to tailor prevention programs to each person's unique genetic makeup.
When a person reaches a disease endpoint, GWAS-based approaches may be used to select the treatments most likely to be effective. Since most inactivating mutations are rare due to negative natural selection, statistical power remains a challenge. To address this, we are well placed to coordinate collaborations with other large-scale studies, and we plan to do reciprocal look-up and meta-analyze results with studies of similar size to improve power. We will also participate in a range of consortia focused on discovery for a wide variety of traits.
Projects
HUNT MCE run a large project called ALL-IN where we look at a wide range of diseases. This is done in close collaboration with clinicians and researchers who specialize in the different areas.
Useful links
Group members
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Mohammad Sayeef Alam PhD Candidate
+4748671602 mohammad.s.alam@ntnu.no HUNT Research Centre -
Aristomo Andries PhD Candidate
aristomo.andries@ntnu.no Department of Public Health and Nursing -
Nikhil Arora Researcher
nikhil.arora@ntnu.no Department of Public Health and Nursing -
Laxmi Bhatta Researcher
+47-73559498 +4773597529 laxmi.bhatta@ntnu.no Department of Clinical and Molecular Medicine -
Artemis Briasouli PhD Candidate
+47-73412821 artemis.briasouli@ntnu.no Department of Public Health and Nursing -
Marta Riise Moksnes Researcher
marta.r.moksnes@ntnu.no HUNT Research Centre -
Elisa Amandine Moreno PhD candidate and Researcher
elisa.moreno@ntnu.no Department of Public Health and Nursing -
Kristian Onarheim PhD Candidate
+4797654244 kristian.onarheim@ntnu.no Department of Public Health and Nursing -
Sweta Pathak PhD student
+4740566542 sweta.pathak@ntnu.no -
Laurent Thomas Researcher
+47-73598416 laurent.thomas@ntnu.no Department of Clinical and Molecular Medicine -
Brooke N. Wolford Researcher
brookewo@ntnu.no Department of Public Health and Nursing