course-details-portlet

SMED8020 - Genetic epidemiology

About

Examination arrangement

Examination arrangement: Assignment and oral examination
Grade: Passed / Not Passed

Evaluation Weighting Duration Grade deviation Examination aids
Assignment 50/100 1 weeks A
Oral examination 50/100 30 minutes A

Course content

The course focuses on the understanding of genetic epidemiology concepts and understanding of genetic variation in the population. Topics to be taught are study design, analysis methods (whole genome, mendelian randomization and functional follow-up), bias and confounding in analyses, implication of functional findings, the use of registry data and ethical considerations.

Learning outcome

After completing the course, the student should:

  • Understand the concepts of genetic epidemiology, understand how genetic variation manifests itself in the population and how it can be studied.
  • Know important tools and analysis methods for genome-wide analyses.
  • Be able to assess and discuss results from such analyses, understand implications of functional findings and suggest follow-up analyses.
  • Know analysis methods and the three main assumptions for MR analyses.
  • Be able to describe the construction of an instrumental variable and assess the validity, strength and weaknesses of such.
  • Be able to assess and discuss results from MR analyses.

Learning methods and activities

Lectures and problem solving. All lectures and problem solving activities are mandatory. The course coordinator may approve up to 20% absence from mandatory lectures/activities. Absence may not be approved if the activity is considered to be critical to the learning outcomes of the course.

Compulsory assignments

  • Presence at lectures

Further on evaluation

In the practical sessions, the students will receive analytical/computational problems to solve and questions to answer. Attendance at all practical sessions is mandatory. The answers from the practical tasks must be submitted at the end of each course day. All practical course work must be approved prior to the oral exam.

On the oral exam, the students are expected to present a scientific paper of choice and will be asked to assess and discuss the data, choice of methods, strengths and weaknesses. A list of papers to chose from will be provided at the beginning of the course week.

Required previous knowledge

Completed Master's degree. Medical students enrolled at the Medical Students' Research Program.

Course materials

Given material, lecture notes and published articles.

Credit reductions

Course code Reduction From To
SMED8021 2.5 AUTUMN 2020
More on the course

No

Facts

Version: 1
Credits:  5.0 SP
Study level: Doctoral degree level

Coursework

Term no.: 1
Teaching semester:  SPRING 2025

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Medicine
Contact information
Course coordinator: Lecturer(s):

Department with academic responsibility
Department of Public Health and Nursing

Examination

Examination arrangement: Assignment and oral examination

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Spring ORD Oral examination 50/100 A
Room Building Number of candidates
Spring ORD Assignment 50/100 A INSPERA
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
Examination

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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