Course - Introduction to Molecular Medicine with Project - MOL3100
Introduction to Molecular Medicine with Project
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About the course
Course content
The lectures will cover the organisation and major features of the human genome, such as replication, gene expression, epigenetics and the role of non-coding RNA. Consequences of mutations and polymorphisms, inherited diseases and molecular aspects of major common diseases, such as cancer, diabetes, vascular and coronary disease are central topics. Infectious diseases and treatment, applied bioinformatics, drug development and use of stem cells and organoids will also be addressed.
Learning outcome
Knowledge
The candidate can
- describe the organization of the human genome and its functional regulation, including replication and maintenance, gene expression, epigenetic modifications, and the role of non-coding RNA
- explain the impact of genes and environment on disease development
- describe how microorganisms cause infection, the mechanisms of action of antimicrobial drugs and how antimicrobial resistance develops
- describe important methods in molecular medicine, including gene editing, the use of stem cells and organoids, and the stages of drug development
- explain how normal cellular processes change, fail, or get destroyed in common complex diseases such as cancer, diabetes, and cardiovascular and brain-related disorders
Skills
The candidate can
- apply and interpret data from simple bioinformatic tools
- collect and evaluate relevant information from articles within molecular medicine
- use EndNote to organize references in a manuscript
Competence
The candidate can
- write a scientific review article about topics within molecular medicine (in English)
- discuss and orally present scientific papers within the field of molecular medicine (in English)
Learning methods and activities
The curriculum of the course is defined by learning objectives. Lectures, computer courses (EndNote and Bioinfomatics), Team-based learing sessions and article presentations are included. The course also includes a compulsory project which accounts for 50 % of the final grade. The language of instruction and examination is English.
Compulsory assignments
- Article presentation
Further on evaluation
The student must have completed the compulsory assignment (article presentation) to take the exam. Exam evaluation is based on two examination arrangements, project paper assignment (weighting 50/100) and written school examination (weighting 50/100). Both parts must be passed.
Retake of the exam: Students with legitimate leave of absence at the final examination and students who receive the grade F may re-sit the examination in the following semester. It is sufficient to retake the exam arrangement (project paper or school exam) that is not passed.
Exam must be answered in English.
Specific conditions
Admission to a programme of study is required:
Molecular Medicine (MSMOLMED)
Required previous knowledge
Admission to the Master of Science in Molecular Medicine at NTNU.
Course materials
Suggested textbook: Molecular Medicine - An Introduction Author: Jens Kurreck, Cy Aaron Stein ISBN: 9783527675098
Credit reductions
| Course code | Reduction | From |
|---|---|---|
| MOL3000 | 7.5 sp | Autumn 2013 |
Subject areas
- Molecular Medicine
Contact information
Course coordinator
Lecturers
- Barbara van Loon
- Bodil Merete Kavli
- Duan Chen
- Frank Skorpen
- Katja Scheffler
- Marit Otterlei
- Morten Beck Rye
- Nathalie Jurisch-Yaksi
- Pål Sætrom