course-details-portlet

MOL3023 - Molecular Medical Bacteriology

About

Examination arrangement

Examination arrangement: School exam
Grade: Letter grades

Evaluation Weighting Duration Grade deviation Examination aids
School exam 100/100 4 hours D

Course content

In this course you will study the molecular biology of bacteria which cause infection in humans. We will focus on selected infectious diseases causing both sporadic infections and outbreaks, and the bacteria which cause these diseases. You will study the clinical presentation of the disease and its epidemiology, the genomic structure of the microorganisms, mobile genetic elements and the mechanisms of horizontal gene transfer, virulence factors and how the microorganisms cause disease, and antimicrobial resistance. Further, you will learn about molecular methods for diagnosis and genotyping of bacteria. You will also get experience with basic bioinformatics methods for analysis and comparison of bacterial nucleic acid and genome sequences. Finally, you will study the relation between the human microbiome and health/disease and basic methagenomics methods for microbiome analyses.

Learning outcome

Knowledge

After completion of the course the student should be able to:

  • Demonstrate advanced knowledge about the molecular biology of bacteria including mobile genomic elements and their role in bacterial adaptation.
  • Demonstrate good knowledge about important bacterial pathogens, including epidemiology and role in infection
  • Demonstrate advanced knowledge about molecular methods for detection of bacterial infections
  • Demonstrate advanced knowledge about molecular methods for genotyping of bacteria, and their use in surveillance, transmission and outbreak investigation of bacterial infectious diseases
  • Demonstrate basic knowledge about bioinformatics methods used for quality control, assembly, in silico typing and detection of resistance and virulence genes in bacteria
  • Demonstrate basic knowledge about the human microbiome and metagenomics methods for microbiome analyses

Skills

After completion of the course the student shall be able to:

  • Choose appropriate methods to use for identification and genotyping based on bacterial species and type of clinical problem
  • Evaluate and compare different methods used for sequencing
  • Interpret results from genotyping in a clinical context
  • Perform basic bioinformatics analyses on bacterial genomes
  • Perform quality control, evaluate and interpret results from bioinformatics analyses

General competence

After completion of the course the student shall be able to:

  • Demonstrate an advanced understanding of the most common bacterial pathogens as well as the molecular methods used for detection and genotyping in medical microbiology
  • Evaluate and select appropriate methods to be used in a molecular medical microbiology laboratory

Learning methods and activities

Lectures.

Compulsory assignments

  • Exercise

Further on evaluation

Compulsory activity: A bioinformatics exercise must be approved before the student can take the written exam. Written exam count 100 % of the final grade.

Retake of exam: If the compulsory bioinformatics exercise has been approved in a previous semester, it is sufficient to retake the written exam. If the bioinformatics excercise is not passed, the excercise must be resubmitted and approved before the written exam can be re-taken. Students with legitimate leave of absence at the final examination and students who receive the grade F make re-sit the examination in the following semester.

The language of instruction is English. The compulsory bioinformatics exercise and the written exam must be answered in English.

Course materials

Will be announced.

Credit reductions

Course code Reduction From To
MOL3003 7.5 AUTUMN 2015
MOL8011 7.5 AUTUMN 2015
More on the course

Facts

Version: 1
Credits:  7.5 SP
Study level: Second degree level

Coursework

Term no.: 1
Teaching semester:  AUTUMN 2024

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Molecular Medicine
  • Biochemistry
  • Biology
  • Cell Biology
  • Medicine
Contact information
Course coordinator: Lecturer(s):

Department with academic responsibility
Department of Clinical and Molecular Medicine

Timetable

List view
Calendar view

Examination

Examination arrangement: School exam

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Autumn ORD School exam 100/100 D 2024-12-19 09:00 INSPERA
Room Building Number of candidates
SL520 Sluppenvegen 14 35
Spring UTS School exam 100/100 D INSPERA
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
Examination

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

More on examinations at NTNU