Top photo

Drawing illustrating registration of heath data

Registry research for the healthcare services - Regforsk

Research group

Registry research for the healthcare services - Regforsk

Regforsk is an interdisciplinary research environment that applies principles from randomized trials on registry data to study cause and effect in various treatments and the organization of healthcare services. Regforsk started as a project on capacity pressure in the health care services (2017-2025) and anchored through financial support from The Research Council of Norway (2019-2024). Regforsk aims to contribute with reliable scientific knowledge to support sustainable health services and strengthened public health.  

Researchers widely consider randomized trials the gold standard for determining cause-and-effect relationships. Yet, randomizing changes at the system level has practical and ethical challenges. Healthcare research is therefore largely based on registered data from diverse sources, which in Norway is possible to link on an individual level. Such “real-life data” reflects the use of healthcare in daily practice over an extended period. Given certain assumptions, researchers can use linked registry data to study the effects of treatments and organizational structures. 

Some examples of settings randomly assigning patients to doctors are out-of-hours services and allocation to general practitioners (GPs). In such cases, we can study doctors' preferred treatment and patients' further health outcomes as PhD candidate Schyler Marie Bennett explains with an example of mental healthcare. Another example is GPs retiring, which we assume they do independently of their patients. Thus, retirement can be considered a random event for patients, with effects on healthcare use and health outcomes.

Regforsk stems from NTNU and Trondheim University Hospital and consists of young and experienced researchers with backgrounds in epidemiology, various medical specialties, mathematics and statistics, social sciences, and health economics. Regforsk collaborates closely with several national and international researchers on a wide range of projects, both large and small. We are open to new collaborative opportunities. 


Featured publications

Featured publications

We found heightened risk of suicide following discharge from acute somatic hospitalization, even in the absence of concurrent mental disorders, self-harm, or prior suicide attempts. This was particularly true for elderly individuals and underscores the need for support for patients after discharge.  

Article in BMC Medicine

We found that patients who experienced their general practitioner (GP) retiring or moving had a short-term, moderate increase in contact with out-of-hours GPs and acute hospital services, and a small but persistent increase in daytime GP and planned hospital contacts, compared to patients whose GP remained in the same practice. There was no difference in mortality between the patients. 

Article in BMJ Quality & Safety

We have studied the effects of referrals of elderly patients from out-of-hours services to hospitals in cases where the referral indication is not obvious - cases where some doctors would have chosen not to refer the patient. The study finds that such referrals lead to slightly more use of health services, but that those who are referred have significantly lower mortality over the next six months.  

Article and editorial in BMJ Quality & Safety. 

Location of maternity services involves balancing hospital delivery volume and travel time. It is not random which women give birth in smaller and larger hospitals. We therefore used three different research designs based on different assumptions to triangulate the results for birth outcomes:  

1. We compared women who gave birth in hospitals of different sizes and with varying travel times, adjusted for known common underlying factors.  

2. We compared women with themselves, if they moved between hospital areas between births.  

3. We compared women who lived in neighboring municipalities, but in different hospital areas.  

Triangulation showed opposite conclusions. 

Article in Epidemiology

In the public debate, the focus is often on individuals with obesity and less at the population's BMI development. But what affects healthcare costs the most?  

We found that people with severe obesity have a high individual risk of healthcare use, but they are few and affect total health care costs to a lesser extent than the much larger number of people with obesity. 

This research shows that it is important to consider both the individual and population perspectives when evaluating measures against overweight and obesity, in clinical and health policy decisions, much in line with G. Rose’s discussion in Sick individuals and sick populations, in 1985. 

Article in Tidsskriftet, The Journal of the Norwegian Medical Association.

Research activity

Viser 30 av 219 for
Publikasjoner Forfattere Tidsskrift År
Mortality from external causes in late adolescence and early adulthood by gestational age and sex: a population-based cohort study in four Nordic countries J.F. Bilsteen, S. Opdahl, A. Pulakka, P.I. Finseth, W. Yin, K. Pape, J. Schei, J. Metsala, Andersen A.-M. Nybo, S. Sandin, ...flere forfattere BMC Medicine 2024
Correction to: Risk of suicide after hospitalizations due to acute physical health conditions—a cohort study of the Norwegian population (BMC Medicine, (2024), 22, 1, (396), 10.1186/s12916-024-03623-5) A. Asheim, S.M. Nilsen, E.R. Svedahl, S.L. Kaspersen, O. Bjerkeset, I. Janszky, J.H. Bjorngaard ...flere forfattere BMC Medicine 2024
Risk of suicide after hospitalizations due to acute physical health conditions—a cohort study of the Norwegian population A. Asheim, S.M. Nilsen, E.R. Svedahl, S.L. Kaspersen, O. Bjerkeset, I. Janszky, J.H. Bjorngaard ...flere forfattere BMC Medicine 2024
The healthcare costs of increased body mass index–evidence from The Trøndelag Health Study C.H. Edwards, Bjorngaard J. Hakon, Kinge J. Minet, Vie G. Aberge, V. Halsteinli, R. Odegard, B. Kulseng, Bjornelv G. Waaler ...flere forfattere Health Economics Review 2024
Healthcare use and costs in the last six months of life by level of care and cause of death Y.A. Michel, E. Aas, L.A. Augestad, E. Burger, L. Thoresen, G.W. Bjornelv ...flere forfattere BMC Health Services Research 2024
Sex Differences in Risk: The Need for Appropriate Methods for Causal Inference I. Janszky, J.H. Bjorngaard ...flere forfattere Journal of the American College of Cardiology 2024
The Spillover Effects of Extending Liver Transplantation to Patients with Colorectal Liver Metastases: A Discrete Event Simulation Analysis H.M. Sjule, C.N. Vinter, S. Dueland, P.-D. Line, E. Burger, G.W. Bjornelv ...flere forfattere Medical Decision Making 2024
Cohort Profile Update: The Young-HUNT Study, Norway V. Rangul, T.L. Holmen, A. Langhammer, J.M. Ingul, K. Pape, J. Fenstad, K. Kvaloy ...flere forfattere International Journal of Epidemiology 2024
General practitioners retiring or relocating and its association with healthcare use and mortality: a cohort study using Norwegian national data K.H. Vinjerui, A. Asheim, K.S. Anthun, F. Carlsen, B.P. Mjolstad, S.M. Nilsen, K. Pape, J.H. Bjorngaard ...flere forfattere BMJ Quality and Safety 2024
Hvor skal vi plassere ambulansene våre? T.R. Bovim, A. Asheim ...flere forfattere Tidsskrift for den Norske Legeforening 2024
Effects of Inpatient Occupational Rehabilitation vs. Outpatient Acceptance and Commitment Therapy on Sick Leave and Cost of Lost Production: 7-Year Follow-Up of a Randomized Controlled Trial L. Aasdahl, S. Gismervik, R. Johnsen, O. Vasseljen, G.W. Bjornelv, J.H. Bjorngaard, M.S. Fimland ...flere forfattere Journal of Occupational Rehabilitation 2024
Kasus–overkrysningsstudier S. Lydersen, J.H. Bjorngaard ...flere forfattere Tidsskrift for den Norske Laegeforening 2024
Dynamic Relationship Between Protective Factors and Violent Outcomes Assessed Using the Structured Assessment of Protective Factors (SAPROF) in Secure Forensic Services A. Haines-Delmont, J.H. Bjorngaard, A. Brown, A. Bruen, A. Tsang, A. Wall, R. Whittington ...flere forfattere Journal of Forensic Psychology Research and Practice 2024
Using machine learning to assess the extent of busy ambulances and its impact on ambulance response times: A retrospective observational study L.E. Naess, A. Kruger, O. Uleberg, H. Haugland, J. Dale, J.-O. Watto, S.M. Nilsen, A. Asheim ...flere forfattere PLoS ONE 2024
Guideline evaluation and implementation mechanisms in school health services (GuideMe): protocol for a hybrid randomized factorial trial A. Sagatun, T. Engell, M. Brekke, H. Sjolie, S.M. Ekornes, K.S. Waldum-Grevboe, K. Pape, K. Kvaloy, A. Jeneson, A.S. Troan, ...flere forfattere BMC Health Services Research 2023
Prioritering – den gylne regel G.W. Bjornelv, C.H. Edwards ...flere forfattere Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 2023
Effectiveness of 'motivational interviewing' on sick leave: a randomized controlled trial in a social insurance setting L. Aasdahl, M.I. Standal, R. Hagen, M. Solbjor, G. Bagoien, H. Fossen, V.S. Foldal, J.H. Bjorngaard, T. Rysstad, M. Grotle, ...flere forfattere Scandinavian Journal of Work, Environment and Health 2023
Preterm birth and the risk of multimorbidity in adolescence: a multiregister-based cohort study K. Heikkila, J. Metsala, A. Pulakka, S.M. Nilsen, M. Kivimaki, K. Risnes, E. Kajantie ...flere forfattere The Lancet Public Health 2023
Economic Evaluation of Inpatient Multimodal Occupational Rehabilitation vs. Outpatient Acceptance and Commitment Therapy for Sick-Listed Workers with Musculoskeletal- or Common Mental Disorders L. Aasdahl, M.S. Fimland, G.W. Bjornelv, S. Gismervik, R. Johnsen, O. Vasseljen, V. Halsteinli ...flere forfattere Journal of Occupational Rehabilitation 2023
Gestational age at birth and hospitalisations for infections among individuals aged 0–50 years in Norway: a longitudinal, register-based, cohort study S.M. Nilsen, J. Valand, T. Rogne, A. Asheim, W. Yin, J. Metsala, S. Opdahl, H. Dollner, J.K. Damas, E. Kajantie, ...flere forfattere eClinicalMedicine 2023
General practitioners ending their practice and impact on patients' health, healthcare use and mortality: A protocol for national registry cohort studies in Norway, 2008 to 2021 K.H. Vinjerui, Anthun K. Sarheim, A. Asheim, F. Carlsen, B.P. Mjolstad, S.M. Nilsen, K. Pape, J.H. Bjorngaard ...flere forfattere BMJ Open 2023
Impact of altering referral threshold from out-of-hours primary care to hospital on patient safety and further health service use: a cohort study E.R. Svedahl, K. Pape, B. Austad, G.A. Vie, Anthun K. Sarheim, F. Carlsen, N.M. Davies, J.H. Bjorngaard ...flere forfattere BMJ Quality and Safety 2023
Violence Exposed Nepalese Pregnant Women have an Accepting Attitude to Domestic Violence and Suffer from Emotional Distress K.D. Pun, J.H. Bjorngaard, B. Schei, E. Darj ...flere forfattere Kathmandu University medical journal (KUMJ) 2023
Cost-Effectiveness of Vaccination of Older Adults with an MF59®-Adjuvanted Quadrivalent Influenza Vaccine Compared to Standard-Dose and High-Dose Vaccines in Denmark, Norway, and Sweden J. Jacob, T. Biering-Sorensen, Ehlers L. Holger, C.H. Edwards, K.G.-I. Mohn, A. Nilsson, J. Hjelmgren, W. Ma, Y. Sharma, E. Ciglia, ...flere forfattere Vaccines 2023
Risk of antidepressant initiation among users of cardiovascular agents and metformin.: Findings from the Trøndelag Health Study (HUNT) and Norwegian Prescription Database (NorPD), Norway I. Bojanic, O. Bjerkeset, L.J. Williams, M. Berk, J.H. Bjorngaard, E.R. Sund, H. Sletvold ...flere forfattere Pharmacology Research and Perspectives 2023
Labour market participation after spinal cord injury. A register-based cohort study A. Halvorsen, A. Steinsbekk, A.S. Leiulfsrud, M.W.M. Post, F. Biering-Sorensen, K. Pape ...flere forfattere Spinal Cord 2023
Utopia for Norwegian helicopter emergency medical services: Estimating the number of bases needed to radically bring down response times, and lives needed to be saved for cost effectiveness C.J. Jagtenberg, O. Uleberg, G.W. Bjornelv, J. Roislien ...flere forfattere PLoS ONE 2023
Use of general practitioner services among youth and young adults in Norway from 2006 to 2021 K. Wahlberg, K. Pape, B. Austad, G.A. Vie ...flere forfattere Scandinavian Journal of Primary Health Care 2023
Kostnadseffektivitetsanalyse: et rammeverk for prioriteringskriteriene G.W. Bjornelv, E. Aas ...flere forfattere Tidsskrift for den Norske Laegeforening 2023
Helsetjenestekostnader ved overvekt og fedme på individnivå versus populasjonsnivå – en HUNT-studie C.H. Edwards, G.W. Bjornelv, K. Ovretveit, K. Hveem, J.H. Bjorngaard ...flere forfattere Tidsskrift for den Norske Laegeforening 2023
Publikasjonsdata lastet ned ukentlig fra Scopus-API via  api.elsevier.com og www.scopus.com.

Linkedin

LinkedIn - Microsoft Apps Follow us on LinkedIn


Regforsk researchers

Funding

Funding