Trygve Brautaset

About

Trygve Brautaset is a Professor in synthetic biology and his research focus is within microbial molecular biology. Brautaset is project leader on three ongoing ERA projects. Brautaset is also leader for Centre for Digital Life Norway, he is a member of the Norwegian Biotechnology advisory board and he is board member for the biotech company Vectron Biosolutions.

Publications

2024

Gamlund, Espen; Barra, Mathias; Brautaset, Trygve. (2024) Surrogati bør ikke straffes. Morgenbladet
Reader opinion piece
Perez Garcia, Fernando; Fernandes de Brito, Luciana; Bakken, Thea Isabel; Brautaset, Trygve. (2024) Riboflavin overproduction from diverse feedstocks with engineered Corynebacterium glutamicum. Biofabrication
Academic article
Bastem, Gülsüm Merve; Sayar, Nihat Alpagu; Fernandes de Brito, Luciana; Brautaset, Trygve; Virant, David; Sariyar Akbulut, Berna. (2024) Development of a novel process towards an L-malate biorefinery using methanol as feedstock. Chemical engineering research & design
Academic article

2023

Bratlie, Sigrid; Holst-Jensen, Arne; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Tøndel, Camilla. (2023) På tide å åpne for genteknologi i norsk matproduksjon. Nationen
Feature article
Bratlie, Sigrid; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Holst-Jensen, Arne; Tøndel, Camilla. (2023) Mer faglighet fra naturbevegelsen, takk. Klassekampen
Reader opinion piece
Gamlund, Espen; Alsheikh, Muath K; Bratlie, Sigrid; Brautaset, Trygve; Holst-Jensen, Arne; Tøndel, Camilla. (2023) Uetisk å la være å satse på genteknologi. Dagsavisen
Feature article
Wargelius, Anna; Alsheikh, Muath K; Gamlund, Espen; Tøndel, Camilla; Bartmann, Aina; Holst-Jensen, Arne. (2023) Genteknologi i en bærekraftig fremtid. Genteknologiutvalget - Norsk Offentlig Utredning (NOU)
Report
Bratlie, Sigrid; Tøndel, Camilla; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Holst-Jensen, Arne. (2023) GMO-regler må ikke få stoppe utviklingen av avanserte terapier. Dagens medisin
Feature article
Klein, Vivien Jessica; Fernandes de Brito, Luciana; Perez Garcia, Fernando; Brautaset, Trygve; Irla, Marta Katarzyna. (2023) Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol. Microbial Biotechnology
Academic article
Hesjedal, Maria Bårdsen; Brautaset, Trygve; Strand, Roger. (2023) Digital Life Norway - should biotechnology be transdisciplinary?. Edward Elgar Publishing
Academic chapter/article/Conference paper

2022

Klein, Vivien Jessica; Irla, Marta Katarzyna; Gil Lopez, Marina; Brautaset, Trygve; Fernandes de Brito, Luciana. (2022) Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy. Microorganisms
Academic literature review
Perez-Garcia, Fernando; Klein, Vivien Jessica; Fernandes de Brito, Luciana; Brautaset, Trygve. (2022) From Brown Seaweed to a Sustainable Microbial Feedstock for the Production of Riboflavin. Frontiers in Bioengineering and Biotechnology
Academic article

2021

Wendisch, Volker F.; Kosec, Gregor; Heux, Stéphanie; Brautaset, Trygve. (2021) Aerobic Utilization of Methanol for Microbial Growth and Production. Advances in Biochemical Engineering, Biotechnology
Academic literature review
Irla, Marta Katarzyna; Hakvåg, Sigrid; Brautaset, Trygve. (2021) Developing a riboswitch-mediated regulatory system for metabolic flux control in thermophilic bacillus methanolicus. International Journal of Molecular Sciences
Academic article
Fernandes de Brito, Luciana; Irla, Marta Katarzyna; Nærdal, Ingemar; Le, Simone Balzer; Baudoin, Delepine; Heux, Stéphanie. (2021) Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus. Frontiers in Bioengineering and Biotechnology
Academic article
Stenseth, Nils Christian; Baalsrud, Helle Tessand; Jakobsen, Kjetill Sigurd; Brautaset, Trygve; Goksøyr, Anders; Jensen, Nina. (2021) Havgenomet – bevaring og bærekraftig bruk av marine genetiske ressurser i Norge.
Chapter
Brautaset, Trygve. (2021) Genteknologisk vaksine gir nytt håp. Genialt - Tidsskrift fra Bioteknologirådet
Popular scientific article
Khider, May Laura Kilano; Brautaset, Trygve; Irla, Marta Katarzyna. (2021) Methane monooxygenases: central enzymes in methanotrophy with promising biotechnological applications. World Journal of Microbiology & Biotechnology
Academic article
Naderi, Sheida; Visnes, Torkild; Brautaset, Trygve. (2021) Impact of DNA glycosylases on epigenetic regulation of gene expression via active DNA demethylation in human cells. NTNU Open
Masters thesis

2020

Brautaset, Trygve; Jonassen, Inge; Bösl, Korbinian; Norunn K, Torheim. (2020) På tide å sette av fem prosent av prosjektmidlene til datahåndtering? . Khrono.no
Popular scientific article
Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna. (2020) Methanol-based acetoin production by genetically engineered Bacillus methanolicus. Green Chemistry
Academic article
Gawin, Agnieszka Maria; Tietze, Lisa; Aarstad, Olav Andreas; Aachmann, Finn Lillelund; Brautaset, Trygve; Ertesvåg, Helga. (2020) Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family. Scientific Reports
Academic article
Irla, Marta Katarzyna; Drejer, Eivind Bøe; Brautaset, Trygve; Hakvåg, Sigrid. (2020) Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus. Microbial Cell Factories
Academic article
Pfeifenschneider, Johannes; Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F.. (2020) Transaldolase in Bacillus methanolicus: biochemical characterization and biological role in ribulose monophosphate cycle. BMC Microbiology
Academic article
Hakvåg, Sigrid; Nærdal, Ingemar; Heggeset, Tonje Marita Bjerkan; Kristiansen, Kåre Andre; Aasen, Inga Marie; Brautaset, Trygve. (2020) Production of Value-Added Chemicals by Bacillus methanolicus Strains Cultivated on Mannitol and Extracts of Seaweed Saccharina latissima at 50C. Frontiers in Microbiology
Academic article
Allahgholi, Leila; Sardari, Roya R.R.; Hakvåg, Sigrid; Ara, Kazi Z.G.; Kristjansdottir, Thordis Anna; Aasen, Inga Marie. (2020) Composition analysis and minimal treatments to solubilize polysaccharides from the brown seaweed Laminaria digitata for microbial growth of thermophiles. Journal of Applied Phycology
Academic article
Hans, Sebastian; Ulmer, Christian; Narayanan, Harini; Brautaset, Trygve; Krausch, Niels; Neubauer, Peter. (2020) Monitoring Parallel Robotic Cultivations with Online Multivariate Analysis. Processes
Academic article
Gawin, Agnieszka Maria; Ertesvåg, Helga; Hansen, Sine Alise Hartvigsen; Malmo, Jostein; Brautaset, Trygve. (2020) Translational regulation of periplasmic folding assistants and proteases as a valuable strategy to improve production of translocated recombinant proteins in Escherichia coli. BMC Biotechnology
Academic article

2019

Schultenkamper, Kerstin; Fernandes de Brito, Luciana; Lopez, Marina Gil; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
Academic article
Gawin, Agnieszka; Peebo, Karl; Sebastian, Hans; Ertesvåg, Helga; Irla, Marta Katarzyna; Neubauer, Peter. (2019) Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production. Microbial Cell Factories
Academic article
Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2019) Corrigendum Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
Errata
Brautaset, Trygve; Valla, Svein. (2019) Special Issue: Recombinant Protein Expression in Microorganisms. Microorganisms
Short communication
Irla, Marta Katarzyna; Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer. (2019) Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production. Frontiers in Microbiology
Errata
Görbitz, Carl Henrik; Jakobsen, Kjetill Sigurd; Sandve, Simen Rød; Goksøyr, Anders; Brautaset, Trygve; Jørgensen, Trond Ø.. (2019) Den sjette masseutryddelse og Jordens DNA. Aftenposten (morgenutg. : trykt utg.)
Feature article
Schultenkämper, Kerstin; Fernandes de Brito, Luciana; Gil López, Marina; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
Academic article

2018

Johansen, Finn-Eirik; Brautaset, Trygve; Aune, Marie Hjelmseth; Patriksson, Alexandra; Falkenberg, Liv Eggset; Kleppe, Rune. (2018) Centre for Digital Life Norway - Annual report 2017. Senter for Digialt Liv Norge
Report
Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve. (2018) Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae. Microorganisms
Academic literature review
Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
Doctoral dissertation

2017

Irla, Marta; Nærdal, Ingemar; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains. Industrial crops and products (Print)
Academic article
Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
Academic article
Brautaset, Trygve. (2017) Bioteknologi. Fagbokforlaget
Chapter
Gawin, Agnieszka; Valla, Svein; Brautaset, Trygve. (2017) The XylS/Pm regulator/promoter system and its use in fundamental studies of bacterial gene expression, recombinant protein production and metabolic engineering. Microbial Biotechnology
Academic literature review
Le, Simone Balzer; Heggset, Tonje Marita Bjerkan; Haugen, Tone; Nærdal, Ingemar; Brautaset, Trygve. (2017) 6-Phosphofructokinase and ribulose-5-phosphate 3-epimerase in methylotrophic Bacillus methanolicus ribulose monophosphate cycle. Applied Microbiology and Biotechnology
Academic article
Nærdal, Ingemar; Netzer, Roman; Irla, Marta; Krog, Anne; Heggset, Tonje Marita Bjerkan; Wendisch, Volker F.. (2017) L-lysine production by Bacillus methanolicus: Genome-based mutational analysis and L-lysine secretion engineering. Journal of Biotechnology
Academic article
Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol as a carbon substrate in the bio-economy: metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals. Biofuels, Bioproducts and Biorefining
Academic literature review

2016

Carnicer, Marc; Vieira, Gilles; Brautaset, Trygve; Portais, Jean-Charles; Heux, Stéphanie. (2016) Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus. Microbial Cell Factories
Academic article
Brautaset, Trygve; Åm, Heidrun; Aune, Marie Hjelmseth. (2016) Dragvoll og Gløshaugen trenger hverandre. Adressavisen
Feature article
Brautaset, Trygve. (2016) Syntetisk biologi - muligheter og trusler. Biolog
Popular scientific article
Wimark, Odd-Gunnar; Brautaset, Trygve. (2016) Report: Synthetic biology - biosafety and contribution to addressing societal challenges Chapter 1: Synthetic Biology: Science, Experimental Approaches and Applications in Biotechnology. GenØk – Senter for biosikkerhet, Forskningsparken i Breivika, Postboks 6418, 9294 Tromsø
Report
Irla, Marta; Heggset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer. (2016) Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production. Frontiers in Microbiology
Academic article
Aasen, Inga Marie; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Liu, Bin; Brautaset, Trygve; Vadstein, Olav. (2016) Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids. Applied Microbiology and Biotechnology
Academic literature review
Liu, Bin; Ertesvåg, Helga; Aasen, Inga Marie; Vadstein, Olav; Brautaset, Trygve; Heggeset, Tonje Marita Bjerkan. (2016) Draft genome sequence of the docosahexaenoic acid producing thraustochytrid Aurantiochytrium sp. T66. Genomics Data
Academic article

2015

Almaas, Eivind; Brautaset, Trygve. (2015) Syntetisk biologi. Gyldendal Norsk Forlag A/S
Popular scientific chapter/article
Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2015) Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
Academic article
Irla, Marta; Neshat, Armin; Brautaset, Trygve; Rückert, Christian; Kalinowski, Jörn; Wendisch, Volker F.. (2015) Transcriptome analysis of thermophilic methylotrophic Bacillus methanolicus MGA3 using RNA-sequencing provides detailed insights into its previously uncharted transcriptional landscape. BMC Genomics
Academic article
Müller, Jonas E.N.; Meyer, Fabian; Litsanov, Boris; Kiefer, Patrick; Potthoff, Eva; Heux, Stéphanie. (2015) Engineering Escherichia coli for methanol conversion. Metabolic Engineering
Academic article

2011

Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2011) Broad-Host-Range Plasmid Vectors for Gene Expression in Bacteria. Springer Science+Business Media B.V.
Academic chapter/article/Conference paper
Nærdal, Ingemar; Netzer, Roman; Ellingsen, Trond Erling; Brautaset, Trygve. (2011) Analysis and Manipulation of Aspartate Pathway Genes for L-Lysine Overproduction from Methanol by Bacillus methanolicus. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Ellingsen, Trond Erling. (2011) Lysine: Industrial Uses and Production. Elsevier
Academic chapter/article/Conference paper
Lale, Rahmi; Berg, Laila; Stuttgen, Friederike; Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Brautaset, Trygve. (2011) Continuous Control of the Flow in Biochemical Pathways through 5 ' Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Sletta, Håvard; Degnes, Kristin Fløgstad; Sekurova, Olga; Bakke, Ingrid; Volokhan, Olga. (2011) New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei. Applied and Environmental Microbiology
Academic article

2010

Aune, Trond Erik Vee; Bakke, Ingrid; Drabløs, Finn; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2010) Directed evolution of the transcription factor XylS for development of improved expression systems. Microbial Biotechnology
Academic article
Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Degnes, Kristin F.; Netzer, Roman; Nærdal, Ingemar; Krog, Anne. (2010) Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50°C. Applied Microbiology and Biotechnology
Academic article
Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Andreassen, Trygve; Goksøyr, Audun; Bruheim, Per; Brautaset, Trygve. (2010) Biosynthetic Pathway for g-Cyclic Sarcinaxanthin in Micrococcus luteus: Heterologous Expression and Evidence for Diverse and Multiple Catalytic Functions of C50 Carotenoid Cyclases. Journal of Bacteriology
Academic article

2009

Bakke, Ingrid; Berg, Laila; Aune, Trond Erik Vee; Brautaset, Trygve; Sletta, Håvard; Tøndervik, Anne. (2009) Random Mutagenesis of the Pm Promoter as a Powerful Strategy for Improvement of Recombinant-Gene Expression. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Lale, Rahmi; Valla, Svein. (2009) Minireview - Positively regulated bacterial expression systems. Microbial Biotechnology
Academic article
Jakobsen, Øyvind Mejdell; Brautaset, Trygve; Degnes, Kristin F.; Heggeset, Tonje M.B.; Balzer, Simone; Flickinger, Michael C.. (2009) Overexpression of Wild-Type Aspartokinase Increases L-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology
Academic article

2008

Brautaset, Trygve; Sletta, Håvard; Nedal, Aina; Borgos, Sven Even F.; Degnes, Kristin F.; Bakke, Ingrid. (2008) Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei. Chemistry and Biology
Academic article
Brautaset, Trygve. (2008) Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei. Chemistry and Biology
Academic article

2007

Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Josefsen, Kjell D.; Flickinger, Michael C.; Ellingsen, Trond Erling. (2007) Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50°C. Applied Microbiology and Biotechnology
Academic literature review
Sletta, Håvard; Tøndervik, Anne; Hakvåg, Sigrid; Nedal, Aina; Aune, Trond Erik Vee; Aune, Randi. (2007) The presence of N-terminal secretion signal sequences leads to strong stimulation of the total expression levels of three tested medically important proteins during high-cell-density cultivations of Escherichia coli. Applied and Environmental Microbiology
Academic article
Nedal, Aina; Sletta, Håvard; Brautaset, Trygve; Borgos, Sven Even F.; Sekurova, Olga; Ellingsen, Trond E.. (2007) Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455. Applied and Environmental Microbiology
Academic article

2006

Borgos, Sven Even F.; Sletta, Håvard; Fjærvik, Espen; Brautaset, Trygve; Ellingsen, Trond Erling; Gulliksen, Ole-Martin. (2006) Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis. Archives of Microbiology
Academic article
Jakobsen, Øyvind Mejdell; Benichou, Aline; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2006) Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus. Journal of Bacteriology
Academic article

2005

Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2005) Plasmid-dependent methylotrophy and its significance for the Biology of thermotolerant bacterium Bacillus methanolicus. Journal of Biotechnology
Abstract

2004

Sletta, Håvard; Nedal, Aina; Aune, Trond Erik Vee; Hellebust, H.; Hakvåg, Sigrid; Aune, R.. (2004) Broad-host-range plasmid pJB658 can be used for industrial-level production of a secreted host-toxic single-chain antibody fragment in Escherichia coli. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling. (2004) Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicus. Journal of Bacteriology
Academic article
Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, OM; Ellingsen, Trond Erling. (2004) In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. Journal of Bacteriology
Academic article

2003

Brautaset, Trygve; Williams, Mark; Dillingham, Richard; Flickinger, Michael. (2003) The role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine secreting mutants. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin synthesis in Streptomyces noursei. Journal of Biological Chemistry
Academic article
Brautaset, Trygve; Williams, Mark D.; Dillingham, Richard D.; Kaufmann, Christine; Bennaars, Assumpta; Crabbe, Edward. (2003) Role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine-secreting mutants. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei. Journal of Biological Chemistry
Academic article

2002

Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Hagen, Lars; Ellingsen, Trond E.; Strøm, Arne Reidar. (2002) Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. Chemistry and Biology
Academic article

2001

Brautaset, Trygve; Zotchev, Sergey. (2001) Cloning and sequencing of a polyene antibiotic biosynthetic gene cluster. QIAGEN Newsletter
Academic article

2000

Brautaset, Trygve; Petersen, Steffen B.; Valla, Svein. (2000) In vitro determined kinetic properties of mutant phosphoglucomutases and their effects on sugar catabolism in Escherichia coli. Metabolic Engineering
Academic article
Winther-Larsen, Hanne C.; Josefsen, Kjell D.; Brautaset, Trygve; Valla, Svein. (2000) Parameters affecting gene expression from the Pm promoter in gram-negative bacteria. Metabolic Engineering
Academic article
Winther-Larsen, Hanne C.; Blatny, Janet M.; Valand, Bjørnar; Brautaset, Trygve; Valla, Svein. (2000) Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. Metabolic Engineering
Academic article
Brautaset, Trygve; Sekurova, Olga; Sletta, Håvard; Ellingsen, Trond E.; Strøm, Arne Reidar; Valla, Svein. (2000) Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455 : analysis of the gene cluster and deduction of the biosynthetic pathway. Chemistry and Biology
Academic article

1999

Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria - an approach to creating new antibiotics. NBS-nytt
Academic article
Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria- an approach to creating new antibiotics. NBS-nytt
Academic article
Brautaset, Trygve. (1999) Enzyme Engineering. NBS-nytt
Academic article

1998

Brautaset, Trygve; Petersen, Steffen; Valla, Svein. (1998) An Experimental study on carbon flow in Escherichia coli as a function of kinetic properties and expression levels of the enzyme phosphoglucomutase. Biotechnology and Bioengineering
Academic article
Brautaset, Trygve. (1998) Phosphoglucomutase and its mutant derivatives as models for studies of carbon flow in Escherichia coli. NTNU Trondheim Norwegian University of Science and Technology
Doctoral dissertation

1997

Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article
Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Karunakaran, Ponniah; Valla, Svein. (1997) Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. Plasmid
Academic article
Blatny, Janet Martha; Karunakaran, Ponniah; Brautaset, Trygve; Knutsen, Torill Irene; Winther-Larsen, Hanne C.; Valla, Svein. (1997) New RK2 vectors useful in biotechnology and for analyses of RK2 replication and copy number control. Plasmid
Academic article
Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve. (1997) Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article

1996

Valla, Svein; Brautaset, Trygve. (1996) Metabolsk ingeniørkunst; Hva er det og hva kan det brukes til?. Kjemi
Academic article

1995

Baptista, Antonio; Brautaset, Trygve; Drabløs, Finn; Martel, Paulo; Valla, Svein; Petersen, Steffen-B.. (1995) Electrostatic studies of carbohydrate active enzymes. Carbohydrate bioengineering : proceedings of an international conference
Academic article

1994

Brautaset, Trygve; Standal, Rune; Fjærvik, Espen; Valla, Svein. (1994) Nucleotide sequence and expression analysis of the Acetobacter xylinum phosphoglucomutase gene. Microbiology
Academic article

Journal publications

Gamlund, Espen; Barra, Mathias; Brautaset, Trygve. (2024) Surrogati bør ikke straffes. Morgenbladet
Reader opinion piece
Perez Garcia, Fernando; Fernandes de Brito, Luciana; Bakken, Thea Isabel; Brautaset, Trygve. (2024) Riboflavin overproduction from diverse feedstocks with engineered Corynebacterium glutamicum. Biofabrication
Academic article
Bastem, Gülsüm Merve; Sayar, Nihat Alpagu; Fernandes de Brito, Luciana; Brautaset, Trygve; Virant, David; Sariyar Akbulut, Berna. (2024) Development of a novel process towards an L-malate biorefinery using methanol as feedstock. Chemical engineering research & design
Academic article
Bratlie, Sigrid; Holst-Jensen, Arne; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Tøndel, Camilla. (2023) På tide å åpne for genteknologi i norsk matproduksjon. Nationen
Feature article
Bratlie, Sigrid; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Holst-Jensen, Arne; Tøndel, Camilla. (2023) Mer faglighet fra naturbevegelsen, takk. Klassekampen
Reader opinion piece
Gamlund, Espen; Alsheikh, Muath K; Bratlie, Sigrid; Brautaset, Trygve; Holst-Jensen, Arne; Tøndel, Camilla. (2023) Uetisk å la være å satse på genteknologi. Dagsavisen
Feature article
Bratlie, Sigrid; Tøndel, Camilla; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Holst-Jensen, Arne. (2023) GMO-regler må ikke få stoppe utviklingen av avanserte terapier. Dagens medisin
Feature article
Klein, Vivien Jessica; Fernandes de Brito, Luciana; Perez Garcia, Fernando; Brautaset, Trygve; Irla, Marta Katarzyna. (2023) Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol. Microbial Biotechnology
Academic article
Klein, Vivien Jessica; Irla, Marta Katarzyna; Gil Lopez, Marina; Brautaset, Trygve; Fernandes de Brito, Luciana. (2022) Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy. Microorganisms
Academic literature review
Perez-Garcia, Fernando; Klein, Vivien Jessica; Fernandes de Brito, Luciana; Brautaset, Trygve. (2022) From Brown Seaweed to a Sustainable Microbial Feedstock for the Production of Riboflavin. Frontiers in Bioengineering and Biotechnology
Academic article
Wendisch, Volker F.; Kosec, Gregor; Heux, Stéphanie; Brautaset, Trygve. (2021) Aerobic Utilization of Methanol for Microbial Growth and Production. Advances in Biochemical Engineering, Biotechnology
Academic literature review
Irla, Marta Katarzyna; Hakvåg, Sigrid; Brautaset, Trygve. (2021) Developing a riboswitch-mediated regulatory system for metabolic flux control in thermophilic bacillus methanolicus. International Journal of Molecular Sciences
Academic article
Fernandes de Brito, Luciana; Irla, Marta Katarzyna; Nærdal, Ingemar; Le, Simone Balzer; Baudoin, Delepine; Heux, Stéphanie. (2021) Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus. Frontiers in Bioengineering and Biotechnology
Academic article
Brautaset, Trygve. (2021) Genteknologisk vaksine gir nytt håp. Genialt - Tidsskrift fra Bioteknologirådet
Popular scientific article
Khider, May Laura Kilano; Brautaset, Trygve; Irla, Marta Katarzyna. (2021) Methane monooxygenases: central enzymes in methanotrophy with promising biotechnological applications. World Journal of Microbiology & Biotechnology
Academic article
Brautaset, Trygve; Jonassen, Inge; Bösl, Korbinian; Norunn K, Torheim. (2020) På tide å sette av fem prosent av prosjektmidlene til datahåndtering? . Khrono.no
Popular scientific article
Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna. (2020) Methanol-based acetoin production by genetically engineered Bacillus methanolicus. Green Chemistry
Academic article
Gawin, Agnieszka Maria; Tietze, Lisa; Aarstad, Olav Andreas; Aachmann, Finn Lillelund; Brautaset, Trygve; Ertesvåg, Helga. (2020) Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family. Scientific Reports
Academic article
Irla, Marta Katarzyna; Drejer, Eivind Bøe; Brautaset, Trygve; Hakvåg, Sigrid. (2020) Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus. Microbial Cell Factories
Academic article
Pfeifenschneider, Johannes; Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F.. (2020) Transaldolase in Bacillus methanolicus: biochemical characterization and biological role in ribulose monophosphate cycle. BMC Microbiology
Academic article
Hakvåg, Sigrid; Nærdal, Ingemar; Heggeset, Tonje Marita Bjerkan; Kristiansen, Kåre Andre; Aasen, Inga Marie; Brautaset, Trygve. (2020) Production of Value-Added Chemicals by Bacillus methanolicus Strains Cultivated on Mannitol and Extracts of Seaweed Saccharina latissima at 50C. Frontiers in Microbiology
Academic article
Allahgholi, Leila; Sardari, Roya R.R.; Hakvåg, Sigrid; Ara, Kazi Z.G.; Kristjansdottir, Thordis Anna; Aasen, Inga Marie. (2020) Composition analysis and minimal treatments to solubilize polysaccharides from the brown seaweed Laminaria digitata for microbial growth of thermophiles. Journal of Applied Phycology
Academic article
Hans, Sebastian; Ulmer, Christian; Narayanan, Harini; Brautaset, Trygve; Krausch, Niels; Neubauer, Peter. (2020) Monitoring Parallel Robotic Cultivations with Online Multivariate Analysis. Processes
Academic article
Gawin, Agnieszka Maria; Ertesvåg, Helga; Hansen, Sine Alise Hartvigsen; Malmo, Jostein; Brautaset, Trygve. (2020) Translational regulation of periplasmic folding assistants and proteases as a valuable strategy to improve production of translocated recombinant proteins in Escherichia coli. BMC Biotechnology
Academic article
Schultenkamper, Kerstin; Fernandes de Brito, Luciana; Lopez, Marina Gil; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
Academic article
Gawin, Agnieszka; Peebo, Karl; Sebastian, Hans; Ertesvåg, Helga; Irla, Marta Katarzyna; Neubauer, Peter. (2019) Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production. Microbial Cell Factories
Academic article
Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2019) Corrigendum Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
Errata
Brautaset, Trygve; Valla, Svein. (2019) Special Issue: Recombinant Protein Expression in Microorganisms. Microorganisms
Short communication
Irla, Marta Katarzyna; Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer. (2019) Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production. Frontiers in Microbiology
Errata
Görbitz, Carl Henrik; Jakobsen, Kjetill Sigurd; Sandve, Simen Rød; Goksøyr, Anders; Brautaset, Trygve; Jørgensen, Trond Ø.. (2019) Den sjette masseutryddelse og Jordens DNA. Aftenposten (morgenutg. : trykt utg.)
Feature article
Schultenkämper, Kerstin; Fernandes de Brito, Luciana; Gil López, Marina; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
Academic article
Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve. (2018) Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae. Microorganisms
Academic literature review
Irla, Marta; Nærdal, Ingemar; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains. Industrial crops and products (Print)
Academic article
Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
Academic article
Gawin, Agnieszka; Valla, Svein; Brautaset, Trygve. (2017) The XylS/Pm regulator/promoter system and its use in fundamental studies of bacterial gene expression, recombinant protein production and metabolic engineering. Microbial Biotechnology
Academic literature review
Le, Simone Balzer; Heggset, Tonje Marita Bjerkan; Haugen, Tone; Nærdal, Ingemar; Brautaset, Trygve. (2017) 6-Phosphofructokinase and ribulose-5-phosphate 3-epimerase in methylotrophic Bacillus methanolicus ribulose monophosphate cycle. Applied Microbiology and Biotechnology
Academic article
Nærdal, Ingemar; Netzer, Roman; Irla, Marta; Krog, Anne; Heggset, Tonje Marita Bjerkan; Wendisch, Volker F.. (2017) L-lysine production by Bacillus methanolicus: Genome-based mutational analysis and L-lysine secretion engineering. Journal of Biotechnology
Academic article
Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol as a carbon substrate in the bio-economy: metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals. Biofuels, Bioproducts and Biorefining
Academic literature review
Carnicer, Marc; Vieira, Gilles; Brautaset, Trygve; Portais, Jean-Charles; Heux, Stéphanie. (2016) Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus. Microbial Cell Factories
Academic article
Brautaset, Trygve; Åm, Heidrun; Aune, Marie Hjelmseth. (2016) Dragvoll og Gløshaugen trenger hverandre. Adressavisen
Feature article
Brautaset, Trygve. (2016) Syntetisk biologi - muligheter og trusler. Biolog
Popular scientific article
Irla, Marta; Heggset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer. (2016) Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production. Frontiers in Microbiology
Academic article
Aasen, Inga Marie; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Liu, Bin; Brautaset, Trygve; Vadstein, Olav. (2016) Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids. Applied Microbiology and Biotechnology
Academic literature review
Liu, Bin; Ertesvåg, Helga; Aasen, Inga Marie; Vadstein, Olav; Brautaset, Trygve; Heggeset, Tonje Marita Bjerkan. (2016) Draft genome sequence of the docosahexaenoic acid producing thraustochytrid Aurantiochytrium sp. T66. Genomics Data
Academic article
Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2015) Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
Academic article
Irla, Marta; Neshat, Armin; Brautaset, Trygve; Rückert, Christian; Kalinowski, Jörn; Wendisch, Volker F.. (2015) Transcriptome analysis of thermophilic methylotrophic Bacillus methanolicus MGA3 using RNA-sequencing provides detailed insights into its previously uncharted transcriptional landscape. BMC Genomics
Academic article
Müller, Jonas E.N.; Meyer, Fabian; Litsanov, Boris; Kiefer, Patrick; Potthoff, Eva; Heux, Stéphanie. (2015) Engineering Escherichia coli for methanol conversion. Metabolic Engineering
Academic article
Heider, Sabine; Peters-Wendisch, Petra; Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Brautaset, Trygve; Wendisch, Volker F.. (2014) Production and glucosylation of C50 and C40 carotenoids by metabolically engineered Corynebacterium glutamuicum. Applied Microbiology and Biotechnology
Academic article
Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F.. (2014) Characterization of two transketolases encoded on the chromosome and the plasmid pBM19 of the facultative ribulose monophosphate cycle methylotroph Bacillus methanolicus. BMC Microbiology
Academic article
Müller, Jonas E.N.; Litsanov, Boris; Bortfeld-Miller, Miriam; Trachsel, Christian; Grossmann, Jonas; Brautaset, Trygve. (2014) Proteomic analysis of the thermophilic methylotroph Bacillus methanolicus MGA3. Proteomics
Academic article
Irla, Marta; Neshat, Armin; Winkler, Anika; Albersmeier, Andreas; Heggeset, Tonje Marita Bjerkan; Brautaset, Trygve. (2014) Complete genome sequence of Bacillus methanolicus MGA3, a thermotolerant amino acid producing methylotroph. Journal of Biotechnology
Academic article
Müller, Jonas E.N.; Heggeset, Tonje Marita Bjerkan; Wendisch, Volker F.; Vorholt, Julia A.; Brautaset, Trygve. (2014) Methylotrophy in the thermophilic Bacillus methanolicus, basic insights and application for commodity production from methanol. Applied Microbiology and Biotechnology
Academic article
Kucharova, Veronika; Aakvik, Trine; Almaas, Eivind; Naas, Adrian Ertsås; Brautaset, Trygve; Valla, Svein. (2013) Non-Invasive Analysis of Recombinant mRNA Stability in Escherichia coli by a Combination of Transcriptional Inducer Wash-Out and qRT-PCR. PLOS ONE
Academic article
Tøndervik, Anne; Balzer, Simone; Haugen, Tone; Sletta, Håvard; Rode, Marit; Lindmo, Karine. (2013) High production of recombinant Norwegian salmonid alphavirus E1 and E2 proteins in Escherichia coli by fusion to secretion signal sequences and removal of hydrophobic domains. Biotechnology and Bioprocess Engineering
Academic article
Stolzenberger, J; Linder, SN; Persicke, M; Brautaset, Trygve; Wendisch, VF. (2013) Characterization of Fructose 1,6-Bisphosphatase and Sedoheptulose 1,7-Bisphosphatase from the Facultative Ribulose Monophosphate Cycle Methylotroph Bacillus methanolicus. Journal of Bacteriology
Academic article
Balzer, Simone; Kucharova, Veronika; Megerle, Judith; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2013) A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli. Microbial Cell Factories
Academic article
Krog, Anne; Heggeset, Tonje Marita Bjerkan; Müller, Jonas E.N.; Kupper, Christiane E.; Schneider, Olha; Vorholt, Julia A.. (2013) Methylotrophic Bacillus methanolicus encodes two chromosomal and one plasmid born NAD+ dependent methanol dehydrogenase paralogs with different catalytic and biochemical properties. PLOS ONE
Academic article
Berg, Laila; Aakvik, Trine; Valla, Svein; Brautaset, Trygve. (2013) Combinatorial Mutagenesis and Selection to Understand and Improve Yeast Promoters. Biomedical Research
Academic article
Heggeset, Tonje Marita Bjerkan; Kucharova, Veronika; Nærdal, Ingemar; Valla, Svein; Sletta, Håvard; Ellingsen, Trond Erling. (2013) Combinatorial Mutagenesis and Selection of Improved Signal Sequences and Their Application for High-Level Production of Translocated Heterologous Proteins in Escherichia coli. Applied and Environmental Microbiology
Academic article
Kucharova, Veronika; Skancke, Jørgen; Brautaset, Trygve; Valla, Svein. (2013) Design and optimization of short DNA sequences that can be used as 5' fusion partners for high-level expression of heterologous genes in Escherichia coli. Applied and Environmental Microbiology
Academic article
Krog, Anne; Heggeset, Tonje Marita Bjerkan; Ellingsen, Trond Erling; Brautaset, Trygve. (2013) Functional Characterization of Key Enzymes involved in L-Glutamate Synthesis and Degradation in the Thermotolerant and Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology
Academic article
Berg, Laila; Kucharova, Veronika; Bakke, Ingrid; Valla, Svein; Brautaset, Trygve. (2012) Exploring the 5 '-UTR DNA region as a target for optimizing recombinant gene expression from the strong and inducible Pm promoter in Escherichia coli. Journal of Biotechnology
Academic article
Heggeset, Tonje Marita; Krog, Anne; Balzer, Simone; Wentzel, Alexander; Ellingsen, Trond Erling; Brautaset, Trygve. (2012) Genome Sequence of Thermotolerant Bacillus methanolicus: Features and Regulation Related to Methylotrophy and Production of L-Lysine and L-Glutamate from Methanol. Applied and Environmental Microbiology
Academic article
Nærdal, Ingemar; Netzer, Roman; Ellingsen, Trond Erling; Brautaset, Trygve. (2011) Analysis and Manipulation of Aspartate Pathway Genes for L-Lysine Overproduction from Methanol by Bacillus methanolicus. Applied and Environmental Microbiology
Academic article
Lale, Rahmi; Berg, Laila; Stuttgen, Friederike; Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Brautaset, Trygve. (2011) Continuous Control of the Flow in Biochemical Pathways through 5 ' Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Sletta, Håvard; Degnes, Kristin Fløgstad; Sekurova, Olga; Bakke, Ingrid; Volokhan, Olga. (2011) New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei. Applied and Environmental Microbiology
Academic article
Aune, Trond Erik Vee; Bakke, Ingrid; Drabløs, Finn; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2010) Directed evolution of the transcription factor XylS for development of improved expression systems. Microbial Biotechnology
Academic article
Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Degnes, Kristin F.; Netzer, Roman; Nærdal, Ingemar; Krog, Anne. (2010) Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50°C. Applied Microbiology and Biotechnology
Academic article
Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Andreassen, Trygve; Goksøyr, Audun; Bruheim, Per; Brautaset, Trygve. (2010) Biosynthetic Pathway for g-Cyclic Sarcinaxanthin in Micrococcus luteus: Heterologous Expression and Evidence for Diverse and Multiple Catalytic Functions of C50 Carotenoid Cyclases. Journal of Bacteriology
Academic article
Bakke, Ingrid; Berg, Laila; Aune, Trond Erik Vee; Brautaset, Trygve; Sletta, Håvard; Tøndervik, Anne. (2009) Random Mutagenesis of the Pm Promoter as a Powerful Strategy for Improvement of Recombinant-Gene Expression. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Lale, Rahmi; Valla, Svein. (2009) Minireview - Positively regulated bacterial expression systems. Microbial Biotechnology
Academic article
Jakobsen, Øyvind Mejdell; Brautaset, Trygve; Degnes, Kristin F.; Heggeset, Tonje M.B.; Balzer, Simone; Flickinger, Michael C.. (2009) Overexpression of Wild-Type Aspartokinase Increases L-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Sletta, Håvard; Nedal, Aina; Borgos, Sven Even F.; Degnes, Kristin F.; Bakke, Ingrid. (2008) Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei. Chemistry and Biology
Academic article
Brautaset, Trygve. (2008) Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei. Chemistry and Biology
Academic article
Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Josefsen, Kjell D.; Flickinger, Michael C.; Ellingsen, Trond Erling. (2007) Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50°C. Applied Microbiology and Biotechnology
Academic literature review
Sletta, Håvard; Tøndervik, Anne; Hakvåg, Sigrid; Nedal, Aina; Aune, Trond Erik Vee; Aune, Randi. (2007) The presence of N-terminal secretion signal sequences leads to strong stimulation of the total expression levels of three tested medically important proteins during high-cell-density cultivations of Escherichia coli. Applied and Environmental Microbiology
Academic article
Nedal, Aina; Sletta, Håvard; Brautaset, Trygve; Borgos, Sven Even F.; Sekurova, Olga; Ellingsen, Trond E.. (2007) Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455. Applied and Environmental Microbiology
Academic article
Borgos, Sven Even F.; Sletta, Håvard; Fjærvik, Espen; Brautaset, Trygve; Ellingsen, Trond Erling; Gulliksen, Ole-Martin. (2006) Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis. Archives of Microbiology
Academic article
Jakobsen, Øyvind Mejdell; Benichou, Aline; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2006) Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus. Journal of Bacteriology
Academic article
Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2005) Plasmid-dependent methylotrophy and its significance for the Biology of thermotolerant bacterium Bacillus methanolicus. Journal of Biotechnology
Abstract
Sletta, Håvard; Nedal, Aina; Aune, Trond Erik Vee; Hellebust, H.; Hakvåg, Sigrid; Aune, R.. (2004) Broad-host-range plasmid pJB658 can be used for industrial-level production of a secreted host-toxic single-chain antibody fragment in Escherichia coli. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling. (2004) Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicus. Journal of Bacteriology
Academic article
Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, OM; Ellingsen, Trond Erling. (2004) In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. Journal of Bacteriology
Academic article
Brautaset, Trygve; Williams, Mark; Dillingham, Richard; Flickinger, Michael. (2003) The role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine secreting mutants. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin synthesis in Streptomyces noursei. Journal of Biological Chemistry
Academic article
Brautaset, Trygve; Williams, Mark D.; Dillingham, Richard D.; Kaufmann, Christine; Bennaars, Assumpta; Crabbe, Edward. (2003) Role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine-secreting mutants. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei. Journal of Biological Chemistry
Academic article
Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Hagen, Lars; Ellingsen, Trond E.; Strøm, Arne Reidar. (2002) Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. Chemistry and Biology
Academic article
Brautaset, Trygve; Zotchev, Sergey. (2001) Cloning and sequencing of a polyene antibiotic biosynthetic gene cluster. QIAGEN Newsletter
Academic article
Brautaset, Trygve; Petersen, Steffen B.; Valla, Svein. (2000) In vitro determined kinetic properties of mutant phosphoglucomutases and their effects on sugar catabolism in Escherichia coli. Metabolic Engineering
Academic article
Winther-Larsen, Hanne C.; Josefsen, Kjell D.; Brautaset, Trygve; Valla, Svein. (2000) Parameters affecting gene expression from the Pm promoter in gram-negative bacteria. Metabolic Engineering
Academic article
Winther-Larsen, Hanne C.; Blatny, Janet M.; Valand, Bjørnar; Brautaset, Trygve; Valla, Svein. (2000) Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. Metabolic Engineering
Academic article
Brautaset, Trygve; Sekurova, Olga; Sletta, Håvard; Ellingsen, Trond E.; Strøm, Arne Reidar; Valla, Svein. (2000) Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455 : analysis of the gene cluster and deduction of the biosynthetic pathway. Chemistry and Biology
Academic article
Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria - an approach to creating new antibiotics. NBS-nytt
Academic article
Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria- an approach to creating new antibiotics. NBS-nytt
Academic article
Brautaset, Trygve. (1999) Enzyme Engineering. NBS-nytt
Academic article
Brautaset, Trygve; Petersen, Steffen; Valla, Svein. (1998) An Experimental study on carbon flow in Escherichia coli as a function of kinetic properties and expression levels of the enzyme phosphoglucomutase. Biotechnology and Bioengineering
Academic article
Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article
Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Karunakaran, Ponniah; Valla, Svein. (1997) Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. Plasmid
Academic article
Blatny, Janet Martha; Karunakaran, Ponniah; Brautaset, Trygve; Knutsen, Torill Irene; Winther-Larsen, Hanne C.; Valla, Svein. (1997) New RK2 vectors useful in biotechnology and for analyses of RK2 replication and copy number control. Plasmid
Academic article
Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article
Brautaset, Trygve. (1997) Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
Academic article
Valla, Svein; Brautaset, Trygve. (1996) Metabolsk ingeniørkunst; Hva er det og hva kan det brukes til?. Kjemi
Academic article
Baptista, Antonio; Brautaset, Trygve; Drabløs, Finn; Martel, Paulo; Valla, Svein; Petersen, Steffen-B.. (1995) Electrostatic studies of carbohydrate active enzymes. Carbohydrate bioengineering : proceedings of an international conference
Academic article
Brautaset, Trygve; Standal, Rune; Fjærvik, Espen; Valla, Svein. (1994) Nucleotide sequence and expression analysis of the Acetobacter xylinum phosphoglucomutase gene. Microbiology
Academic article

Part of book/report

Hesjedal, Maria Bårdsen; Brautaset, Trygve; Strand, Roger. (2023) Digital Life Norway - should biotechnology be transdisciplinary?. Edward Elgar Publishing
Academic chapter/article/Conference paper
Stenseth, Nils Christian; Baalsrud, Helle Tessand; Jakobsen, Kjetill Sigurd; Brautaset, Trygve; Goksøyr, Anders; Jensen, Nina. (2021) Havgenomet – bevaring og bærekraftig bruk av marine genetiske ressurser i Norge.
Chapter
Brautaset, Trygve. (2017) Bioteknologi. Fagbokforlaget
Chapter
Almaas, Eivind; Brautaset, Trygve. (2015) Syntetisk biologi. Gyldendal Norsk Forlag A/S
Popular scientific chapter/article
Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2011) Broad-Host-Range Plasmid Vectors for Gene Expression in Bacteria. Springer Science+Business Media B.V.
Academic chapter/article/Conference paper
Brautaset, Trygve; Ellingsen, Trond Erling. (2011) Lysine: Industrial Uses and Production. Elsevier
Academic chapter/article/Conference paper

Report

Wargelius, Anna; Alsheikh, Muath K; Gamlund, Espen; Tøndel, Camilla; Bartmann, Aina; Holst-Jensen, Arne. (2023) Genteknologi i en bærekraftig fremtid. Genteknologiutvalget - Norsk Offentlig Utredning (NOU)
Report
Naderi, Sheida; Visnes, Torkild; Brautaset, Trygve. (2021) Impact of DNA glycosylases on epigenetic regulation of gene expression via active DNA demethylation in human cells. NTNU Open
Masters thesis
Johansen, Finn-Eirik; Brautaset, Trygve; Aune, Marie Hjelmseth; Patriksson, Alexandra; Falkenberg, Liv Eggset; Kleppe, Rune. (2018) Centre for Digital Life Norway - Annual report 2017. Senter for Digialt Liv Norge
Report
Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
Doctoral dissertation
Wimark, Odd-Gunnar; Brautaset, Trygve. (2016) Report: Synthetic biology - biosafety and contribution to addressing societal challenges Chapter 1: Synthetic Biology: Science, Experimental Approaches and Applications in Biotechnology. GenØk – Senter for biosikkerhet, Forskningsparken i Breivika, Postboks 6418, 9294 Tromsø
Report
Brautaset, Trygve. (1998) Phosphoglucomutase and its mutant derivatives as models for studies of carbon flow in Escherichia coli. NTNU Trondheim Norwegian University of Science and Technology
Doctoral dissertation

Teaching

Courses

Knowledge Transfer

2024

Lecture

Brautaset, Trygve; Hanssen, Anders Braarud. (2024) Digitalt Liv - et eksperiment - hva har vi fått til og hva har vi lært. Forskningsrådet Fag-Til-Lunsj Foredrag , Lysaker 2024-01-16 - 2024-01-16
Poster

Tanase-Opedal, Mihaela; Brautaset, Trygve; Perez Garcia, Fernando; Lund, Simen Jervell. (2024) Utilization of alternative feedstocks in microbial cultivation to produce value-added compounds – The path to a circular bioeconomy. BioCat, Institutt for kjemi Fakultet for naturvitenskap og t Norwegia Graduate School in Biocatalysis Annual Conference , Stavanger 2024-09-11 - 2024-09-13
Popular scientific lecture

Brautaset, Trygve. (2024) Hvilke muligheter ligger i genteknologi, og hvordan bør teknologien reguleres?. Tekna + Norsk Institutt for Naturforskning NINA Hvilke muligheter ligger i genteknologi, og hvordan bør teknologien reguleres? , Trondheim 2024-02-07 - 2024-02-07
Programme participation

Brautaset, Trygve. (2024) Etikk, status og bruksområder knyttet til syntetisk bioteknologi?. NRKP2/NRK1 NRKP2/NRK1 [TV] 2024-02-18
Popular scientific lecture

Brautaset, Trygve. (2024) Deltager i paneldebatt: Syntetisk biologi og kunstig intelligens. Bioteknologirådet Bioteknologidagen 2024 , DOMUS BIBLIOTHECA, KARL JOHANS GATE 47 – OSLO 2024-02-14 - 2024-02-14
Academic lecture

Brautaset, Trygve. (2024) Replacing food competing fedstocks with CO2, metrhylamine and methanol for a sustainable bioeconomy. Green ERA Hub Green ERA Hub Webinar , On Line 2024-03-21 - 2024-03-21
Popular scientific lecture

Brautaset, Trygve. (2024) Biotrusler og kunstig intelligens- når livets kode blir hacket. Bioteknologirådet Åpen paneldebatt , Literaturhuset Trondheim 2024-04-23 - 2024-04-23

2023

Programme participation

Brautaset, Trygve. (2023) Spørretime på Radio Ekko omkrng den nylig utgitte NOU-rapporten "Genteknologi i en bærekraftig framtid". EKKO Tyholt Trondheim EKKO Tyholt Trondheim [Radio] 2023-06-13
Academic lecture

Brautaset, Trygve. (2023) Synthetic Biology - Opportunities and Threats. Forsvarets Forskningsinstitutt (FFI) Joint Action Terror Expert Workshop 2023 , FFI Lillestrøm 2023-03-08 - 2023-03-10
Interview

Brautaset, Trygve. (2023) Intervju på NRK Radio Ekko omkring "Genteknologi og Genteknologirapporten" . EKKO Tyholt Trondheim EKKO Tyholt Trondheim [Radio] 2023-06-07
Programme participation

Strumke, Inga; Jemterud, Torkild; Brautaset, Trygve; Tiller, Rachel . (2023) Abels ekstra - Er de store oppdagelsenes tid forbi?. NRK Radio NRK Radio [Radio] 2023-02-24
Programme participation

Strumke, Inga; Jemterud, Torkild; Brautaset, Trygve; Tiller, Rachel . (2023) Abels tårn - Helt sikker på at ikke KI vil ta over verden?. NRK Radio NRK Radio [Radio] 2023-02-24
Programme participation

Brautaset, Trygve. (2023) Forsker på å klone mennesker og dyr. Forskerne tøyer grensene for hvor mye menneske og dyr kan blandes. Hvorfor gjør vi det - og hva er de etiske dilemmaene?. Ekko Ekko [Radio] 2023-05-31
Programme participation

Brautaset, Trygve. (2023) Abels Tårn Live Trykkeriet Scene Trondheim. Trykkeriet Scene Trondheim Trykkeriet Scene Trondheim [Radio] 2023-02-17
Programme participation

Brautaset, Trygve. (2023) Abels Tårn sending på NRKP2, Paneldebatt omkring Bioteknologi, havvind og kunstig intelligens. [Radio] 2023-03-31
Lecture

Brautaset, Trygve; Myhr, Anne Ingeborg. (2023) Status of GMO regulation and effects on SFI related activities. SINTEF SFI IB Annual , Trondheim 2023-11-26 - 2023-11-28

2022

Popular scientific lecture

Brautaset, Trygve. (2022) Industriell Bioteknologi og Syntetisk Biologi - Paneldebatt. Bioteknologirådet Bioteknologidagen Trondheim 2022 , Studentersamfundet Trondheim 2022-02-17 - 2022-02-17
Popular scientific lecture

Brautaset, Trygve. (2022) Deltager i paneldebatt om genredigering og dyrevelferd: https://www.bioteknologiradet.no/arrangement/genredigering-og-dyreetikk/ . Bioteknologirådet og CRISPRsalmon-prosjektet: Åpent møte om Genredigering og Dyrevelferd , Folkebiblioteket Trondheim 2022-04-04 - 2022-04-04
Lecture

Brautaset, Trygve. (2022) Paneldebatt Arendalsuka 2022: "Hvordan skal Norge fremme mer innovasjon fra bioteknologisk forskning?" https://www.digitallifenorway.org/norsk/arrangementer/arendalsuka---hvordan-skal-norge-fremme-mer-innova.html . Senter for Digitalt Liv Norge Åpent møte Arendalsuka 2022 , Thon Hotell Arendal 2022-08-18 - 2022-08-18
Lecture

Brautaset, Trygve. (2022) Paneldebatt omkring EMBL's nye program "Molecules to Ecosystems" https://www.digitallifenorway.org/conference/ . Senter for Digitalt Liv Norge DLN ÅPrskonferansen 2022 , Scandic Lerkendal Trondheim 2022-10-20 - 2022-10-21
Programme participation

Brautaset, Trygve. (2022) Deltagelse podcast: "Fremtidens mat og et mere bærekraftig kosthold" https://open.spotify.com/episode/0iMgJstj44tAPUQDTOBR0n?si=b71ef915f6484f52&nd=1 . Friskere Viten Friskere Viten [Radio] 2022-10-10
Popular scientific lecture

Myskja, Bjørn Kåre; Gjerris, Mickey; Bovenkerk, Bernice; Grimm, Herwig; Brautaset, Trygve; Olesen, Ingrid. (2022) Genome editing and animal welfare. Bioteknologirådet, NTNU og Litteraturhuset Åpent møte Litteraturhuset og Bioteknologirådet , Trondheim 2022-04-04 -
Programme participation

Brautaset, Trygve. (2022) Forsker på å klone mennesker og dyr. Ekko Ekko [Radio] 2022-05-19

2021

Academic lecture

Brautaset, Trygve. (2021) Syntetisk Biologi - Muligheter og perspektiver. Ferring Pharmaceuticals Nasjonalt møte for IVF-leger , Gran hotell Oslo 2021-11-12 - 2021-11-13
Programme participation

Brautaset, Trygve. (2021) Deltager i paneldebatt: Transdisiplinaritet i DLN. Forskningsparken Oslo Forskningsparken Oslo [Journal] 2021-11-11
Programme participation

Brautaset, Trygve. (2021) "Bør spedbarn gentestes for Spinal muskelatrofi?". Podcast HealthTalk Podcast HealthTalk [Internet] 2021-06-16
Lecture

Brautaset, Trygve. (2021) "Samfunnsansvarlig forskning og innovasjon i Senter for Digitalt Liv Norge" . Nasjonalt forum for åpen forskning og UiR Hvordan endres forskningshverdagen når åpen forskning blir den nye normalen? , Web 2021-10-18 - 2021-10-19
Interview

Brautaset, Trygve. (2021) Ledet intervju + paneldebatt på sesjon omkring Fosterdiagnostikk dag 1 av Bioteknologidagen 2021. Literaturhuuset i Trondheim Literaturhuuset i Trondheim [Internet] 2021-04-21
Academic lecture

Brautaset, Trygve. (2021) Klimasmarte gener: Syntetisk biologi for bærekraft, klima og miljø. Tekna - Teknisk-naturvitenskapelig forening Tekna seminar - klimasmarte gener , Webinar 2021-02-03 - 2021-02-03

2020

Poster

Brautaset, Trygve; Hakvåg, Sigrid; Nærdal, Ingemar; Heggeset, Tonje Marita Bjerkan; Aasen, Inga Marie. (2020) Bacillus methanolicus as cell factory for conversion of seaweed biomass to value-added chemicals at 50C. Norsk Biokjemisk Selskap (NBS) NBS Vintermøte 2020 , Voss 2020-01-23 - 2020-01-26
Academic lecture

Brautaset, Trygve; Irla, Marta Katarzyna; Drejer, Eivind Bøe. (2020) Methanol-based acetoin production by genetically engineered Bacillus methanolicus. Norsk Biokjemisk Selskap (NBS) NBS Vintermøte 2020 , Voss 2020-01-23 - 2020-01-26
Academic lecture

Brautaset, Trygve. (2020) Responsible Research and Innovation in Centre for Digital Life Norway. ERACoBioTech RRI seminar , Webinar 2020-10-21 - 2020-10-21

2019

Lecture

Brautaset, Trygve. (2019) Senter for Digitalt Liv Norge – erfaringer og veien videre. IBT IBT's weekly Department lunch , IBT's lunch room, NV Faculty, NTNU, Gløshaugen 2019-11-27 -
Popular scientific lecture

Brautaset, Trygve. (2019) Invitert deltager paneldiskusjon om Bioteknologi på Technoport 2019, Trondheim. Technoport Paneldiskusjon , Trondheim Claryon Hotell 2019-03-27 - 2019-03-27
Academic lecture

Brautaset, Trygve. (2019) Research on marine biotechnology at NTNU Department of Biotechnology and Food Sciences. Aqua Nor Seminar/Workshop , Sintef Sealab, Brattøra, Trondheim 2019-08-23 - 2019-08-23
Popular scientific lecture

Brautaset, Trygve. (2019) Deltager paneldiskusjon om Genredigert mat Arendalsuka 2019. Arendalsuka Paneldiskusjon , Arendal 2019-08-15 - 2019-08-15
Programme participation

Brautaset, Trygve. (2019) Intervju om stamcelleforskning for organtransplantasjon. NRK EKKO NRK EKKO [Radio] 2019-12-04
Programme participation

Brautaset, Trygve. (2019) Intervju omkring kontroversiell Japansk forskning på stamceller og dyr-menneskehybrider. NRK NorgesGlasset NRK NorgesGlasset [Radio] 2019-08-06
Poster

Christensen, Idd Andrea; Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2019) A New Expression System for Isotope Labelling of Proteins. 40th Danish NMR Meeting 2019-01-21 - 2019-01-22

2018

Lecture

Aune, Marie Hjelmseth; Brautaset, Trygve. (2018) New Call - Digital Life 2018. Centre for Molecular Inflammation Research CEMINAR - CEMIR weekly meeting , trondheim 2018-06-25 -
Interview

Brautaset, Trygve; Strand, Berit Løkensgard; Tarjem, Guro. (2018) Utfordringer for bioteknologien. [Radio] 2018-03-14
Lecture

Brautaset, Trygve. (2018) Bacillus methanolicus: a platform organism for industrial biotechnology. NOBIPOL, NTNU NOBIPOL møte , Meråker 2018-05-03 - 2018-05-04
Academic lecture

Brautaset, Trygve. (2018) Bacillus methanolicus as a platform organism for production of high-value chemicals from alternative non-food raw materials. NBS NBS Contact Meeting , Storefjell 2018-01-18 - 2018-01-20
Academic lecture

Brautaset, Trygve. (2018) Microbial conversion of C1 to value-added products by integrated systems and synthetic biology. Dechema / EraCoBiotech Dechema 2018 / EraCoBiotech kickoff conference , Frankfurt 2018-06-13 - 2018-06-13
Popular scientific lecture

Brautaset, Trygve. (2018) Biotechnology - a science in rapid Development; trends and perspectives. Senter for Digitalt Liv Norge (DLN); Forskerskolen Årskonferanse DLN Forskerskolen , Stiklestad 2018-06-01 - 2018-06-01
Programme participation

Brautaset, Trygve. (2018) Radio Ekko NRKP2 - Intervju/samtale om Senter for Digitalt Liv. NRKP2 NRKP2 [Radio] 2018-03-15
Programme participation

Seres, Silvija; Brautaset, Trygve. (2018) Morgendagens teknologi - Bioteknologi. Podkast Dagens Næringsliv Podkast Dagens Næringsliv [Radio] 2018-04-26
Popular scientific lecture

Brautaset, Trygve; Seres, Silvija. (2018) Bioteknologi. Dagens Næringsliv Kronikk , Oslo 2018-05-15 - 2018-05-15
Popular scientific lecture

Brautaset, Trygve. (2018) Invitert deltager paneldebatt om Norsk deltagelse Earth BioGenome Project. Oslo Innovation Cluster Earth BioGenome Project meeting , Oslo 2018-11-05 - 2018-11-05
Popular scientific lecture

Brautaset, Trygve. (2018) LØRNTECH Podcast - Biotech!. LØRNTECH Podcast v Sunniva Rose og Silvija Seres Podcast LØRNTECH , Oslo 2018-09-21 - 2018-09-21
Interview

Brautaset, Trygve. (2018) Intervju omkring Norsk deltagelse "Earth Biogenome Project". NRKP2, Radio Ekko NRKP2, Radio Ekko [Radio] 2018-11-07
Academic lecture

Brautaset, Trygve. (2018) Products from methanol by metabolic engineering of Bacillus methanolicus. ECB ECB - European Conference in Biotechnology , Geneve 2018-07-01 - 2018-07-04

2017

Poster

Hakvåg, Sigrid; Aasen, Inga Marie; Nærdal, Ingemar; Heggeset, Tonje Marita Bjerkan; Brautaset, Trygve. (2017) Thermophilic cell factories for efficient conversion of brown algae biomass to high-value chemicals. 19th International Conference on Bacilli & Gram-Positive Bacteria , Berlin 2017-06-11 - 2017-06-15
Lecture

Brautaset, Trygve. (2017) Transdisciplinary & Digital Biotechnology. The Life Science Cluster Digital Tools & Methods in Life Sciences - the potential and how to get started , Oslo 2017-02-09 - 2017-02-09
Interview

Normannsen, Sølvi Waterloo; Åm, Heidrun; Brautaset, Trygve. (2017) Ansvarlig forskning i bioteknologi: Heidrun Åm får 10 mill. for å forske på om biotekforskning kommer samfunnet til gode. Universitetsavisa Universitetsavisa [Internet] 2017-02-15
Academic lecture

Brautaset, Trygve. (2017) Bacillus methanolicus: Methylotrophy and Biotechnological Applications. European Summit of industrial biotechnology , Graz, Austria 2017-11-14 - 2017-11-16
Programme participation

Brautaset, Trygve. (2017) Deltager i panelet for RKK P2 Abels Tårn. NTNU Gløshaugen NTNU Gløshaugen [Radio] 2017-05-12
Popular scientific lecture

Brautaset, Trygve. (2017) Paneldeltager i diskusjon på tema: Biotech for competitive and sustainable Industrial Innovation. ERACoBioTech ERACoBioTech panel discussion , Brussel 2017-12-05 - 2017-12-05
Popular scientific lecture

Brautaset, Trygve. (2017) MetApp - Systems biology of bacterial methylotrophy for biotechnological products from methanol. ERA_CoBioTech ERA_CoBioTech Workshop , Brussel 2017-12-05 - 2017-12-06
Programme participation

Brautaset, Trygve. (2017) Intervju på NRK P2 Radio Ekko omkring temaet Syntetisk Biologi. NRK Tyholt, Trondheim NRK Tyholt, Trondheim [Radio] 2017-03-29
Lecture

Brautaset, Trygve. (2017) Thermophilic cell factories for efficient conversion of brown macro algae biomass to high value chemicals . ERA_MBT ERA_MBT Workshop , Lysaker, Oslo 2017-11-20 - 2017-11-21
Lecture

Brautaset, Trygve. (2017) Senter for Digitalt Liv Norge. Norges Tekniske Vitenskapsakademi (NTVA) Kveldsseminar , Lerchendal Gård, Trondheim 2017-09-05 - 2017-09-05
Programme participation

Bruteig, Inga Elise; Jemterud, Torkild; Kruge, Ingvild Ulsaker; Brautaset, Trygve. (2017) Hvordan har gjøken lært å si ko-ko?. NRK P2 Ekko NRK P2 Ekko [Radio] 2017-06-14
Academic lecture

Brautaset, Trygve. (2017) Synthetic biology - an important tool for industrial biotechnology. University of Tromsø ++ BioProsp 2017 , Tromsø 2017-03-08 - 2017-03-10
Academic lecture

Brautaset, Trygve. (2017) Systems Biology approach in drug discovery - a brief introduction and possibilities. University of Tromsø ++ BioProsp 2017 , Tromsø 2017-03-08 - 2017-03-10
Interview

Brautaset, Trygve; Hansen, Kari Eldøen. (2017) Genjakt på den tapte tomatsmak. NRK Viten NRK Viten [Internet] 2017-02-01
Interview

Brautaset, Trygve; Valmot, Odd Richard. (2017) Fra biosement til den nye antibiotikaen: Her er bioteknologiene det skal forskes mer på i Norge. Teknisk Ukeblad Teknisk Ukeblad [Newspaper] 2017-02-09
Interview

Aune, Marie Hjelmseth; Brautaset, Trygve; Normannsen, Sølvi Waterloo. (2017) Senter for digitalt liv: Aldri før har bioteknologene ved NTNU fått større gjennomslag. Universitetsavisa Universitetsavisa [Internet] 2017-02-09

2016

Poster

Kleppe, Rune; Zamanzad Ghavidel, Fatemeh; Aune, Marie Hjelmseth; Brautaset, Trygve; Jonassen, Inge. (2016) Centre for Digital Life Norway A national centre for biotechnology research and innovation. International society for systems biology International Conference on Systems Biology 2016 , Barcelona 2016-09-16 - 2016-09-20
Lecture

Brautaset, Trygve. (2016) Senter for Digitalt Liv Norge. Tekna Tekna - Kveldsseminar , Oslo 2016-06-16 - 2016-06-16
Lecture

Brautaset, Trygve. (2016) Informasjon om Senter for Digitalt Liv Norge. Biotechnology for Biotechnology 2016-08-11 - 2016-08-11
Lecture

Brautaset, Trygve. (2016) Norwegian Center for Digital Life. NBS - Vintermøte 2016-01-21 - 2016-01-24
Lecture

Brautaset, Trygve. (2016) Senter for Digitalt Liv Norge. Tekna - Kveldsseminar , Trondheim 2016-04-26 - 2016-04-26
Academic lecture

Brautaset, Trygve. (2016) Metabolic engineering of methylotrophic bactyerium Bacillus methanolicus. University of Bielefeld, CeBiTech 6th international Bielefeld-CeBiTech research conference , Bielefeld 2016-09-26 - 2016-09-28
Academic lecture

Brautaset, Trygve. (2016) Center for Digital Life Norway - transdisciplinary research, education and innovation. NIBIO Biotechnology for bioeconomy conference , NMBU Ås 2016-08-11 - 2016-08-11
Interview

Aune, Marie Hjelmseth; Brautaset, Trygve; Christensen, Arnfinn. (2016) Laksesimulator og digital hjerne i nytt forskningssenter. forskning.no forskning.no [Internet] 2016-04-20

2015

Interview

Dick, Gunnar; Stølen, Svein; Brautaset, Trygve. (2015) Digital Storsatsing. Populær vitenskapelig bilag- Vitenskap og Historie Populær vitenskapelig bilag- Vitenskap og Historie [Journal] 2015-11-03
Poster

Wendisch, Volker F.; Brautaset, Trygve; Carnicer, J. M.; Heux, Stéphanie; Lessmeier, Lennart; Nærdal, Ingemar. (2015) Methanol-based production of L-lysine and 1,5-diaminopentane. Technology Challenges and Opportunities in Commercializing Industrial Biotechnology , San Diego 2015-09-28 - 2015-09-29
Poster

Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Müller, Jonas E.N.; Krog, Anne; Haugen, Tone; Balzer, Simone. (2015) Thermophilic Bacillus methanolicus, a promising cell factory in the methanol-based bioeconomy. ERASysAPP ERASysAPP – EXCHANGE: Networking and Info Day for research projects of the first ERASysAPP call “Transforming Systems Biology Knowledge into Applications” , Berlin 2015-04-16 - 2015-04-16

2012

Poster

Balzer, Simone; Megerle, Judith; Tøndervik, Anne; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2012) The performance of the XylS/Pm expression cassette in relation to the most commonly used systems for bacterial recombinant expression. Cambridge Healthtech Institute Eighth Annual PEGS- 2012 , Boston, MA 2012-04-30 - 2012-05-04

2009

Academic lecture

Jakobsen, Øyvind Mejdell; Ellingsen, Trond Erling; Brautaset, Trygve. (2009) Metabolic engineering of the bacterium Bacillus methanolicus for overproduction of L-lysine and L-glutamate from methanol. Norsk Biokjemisk Forening NBS Vintermøte 2009 , Røros 2009-01-29 - 2009-02-01

2007

Academic lecture

Brautaset, Trygve. (2007) Genetic tools and optimizations to achieve high level recombinant expression of proteins in Escherichia coli. Symposium to Contact meeting Norwegian Biochemical Society , Lillehammer 2007-02-01 - 2007-02-03

2004

Academic lecture

Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Flickinger, Michael; Valla, Svein; Ellingsen, Trond Erling. (2004) Plasmid-dependent methylotrophy in Thermotolerant Bacillus methanolicus. Annual Meeting Society of Industrial Microbiology , Anaheim 2004-07-25 - 2004-07-29
Academic lecture

Flickinger, Michael; Dillingham, Richard; Brautaset, Trygve; Valla, Svein; Jakobsen, Øyvind Mejdell; Ellingsen, Trond Erling. (2004) Physiology and biochemistry of glutamate and L-lysine biosynthesis from methanol by Bacillus methanolicus at 50C. Annual Meeting Society of Industrial Microbiology , Anaheim 2004-07-25 - 2004-07-29
Academic lecture

Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Flickinger, Michael; Valla, Svein; Ellingsen, Trond Erling. (2004) Bioproduction of L-lysine from methanol: genes critical for methanol consumption are encoded by a 19 kb natural plasmid in Bacillus methanolicus. NBS NBS Winter Meeting , Hafjell 2004-01-15 - 2004-01-18
Academic lecture

Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Flickinger, Michael; Valla, Svein; Ellingsen, Trond Erling. (2004) Unusual physiology of methylotrophic Bacillus methanolicus: impact on metabolic engineering approaches for the bioproduction of lysine. CAMST National Conference on Microbial Sciences and Technology , Oslo 2004-08-29 - 2004-08-31
Poster

Sletta, Håvard; Nedal, Aina; Aune, Trond Erik Vee; Hakvåg, Sigrid; Aune, Randi; Valla, Svein. (2004) Recombinant Production of 1.2 g/l of a funcyional antibody fragment (scFv-phOx) under high-cell-density-cultivations (HCDC) of Escherichia coli. Recombinant Protein Production conference , Tavira 2004-11-11 - 2004-11-14
Poster

Aune, Trond Erik Vee; Brautaset, Trygve; Valla, Svein. (2004) Error-prone PCR and mutational analysis of the transcription regulator XylS from the TOL plasmid of Pseudomonas putida. Recombinant Protein Production conference , Tavira 2004-11-11 - 2004-11-14
Poster

Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2004) Initiation of nystatin biosynthesis: the role of the KSS domain in the loading module of the nystatin polyketide synthase. Biology of Streptomycetes , Munster 2004-02-27 - 2004-03-03

2003

Poster

Brautaset, Trygve; Bruheim, Per; Sekurova, Olga; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.. (2003) Nystatin biosynthesis in Streptomyces noursei: lessons learned from the gene knockout experiments. Biology of Streptomycetes , Münster, Germany 2003-03-03 -
Poster

Brautaset, Trygve; Jakobsen, Ø.M.; Ellingsen, Trond E.; Flickinger, Michael C.. (2003) Metabolic engineering of Bacillus methanolicus for improved L-lysine production. SIM Conference , Minneapolis, USA 2003-08-04 -
Poster

Borgos, Sven Even F.; Fjærvik, E.; Brautaset, Trygve; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Engineered nystatin biosynthesis: From tetraene to heptaene. ISBA meeting 13 , Australia 2003-12-05 -
Poster

Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Initiation of nystatin biosynthesis: the role of the KSs domain in the loading module of the nystatin polyketide synthase. Biology of Streptomycetes , Münster, Germany 2003-03-03 -
Poster

Sekurova, Olga; Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Control over nystatin biosynthesis in Streptomyces noursei: The roles of the pathway-spesific regulators and the NysA loading module. ISBA meeting 13 , Australia 2003-12-05 -
Poster

Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, Ø.M.; Ellingsen, Trond E.. (2003) Four pathway-specific regulators differentially control nystatin biosynthesis in Streptomyces noursei ATCC11455. ISBA meeting 13 , Australia 2003-12-05 -
Academic lecture

Brautaset, Trygve; Sekurova, Olga; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Nystatin biosynthesis in Streptomyces noursei: lessons learned from the gene knockout experiments. Biology of Streptomycetes , Munster 2003-02-27 - 2003-03-03
Academic lecture

Sekurova, Olga; Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Control over nystatin biosynthesis in Streptomyces noursei: The roles of the pathway-specific regulators and the NysA loading module. ISBA Meeting 13 2003-11-10 - 2003-11-14
Academic lecture

Brautaset, Trygve. (2003) Nye systemer for effektiv produksjon av rekombinante proteiner. NBS Annual local NBS Meeting , Teveltunet 2003-10-10 -
Poster

Borgos, Sven Even F.; Fjærvik, Espen; Brautaset, Trygve; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Engineered nystatin biosynthesis: From tetraene to heptaene. ISBA Meeting 13 2003-11-10 - 2003-11-14
Poster

Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, Øyvind Mejdell; Ellingsen, Trond Erling. (2003) Four pathway-specific regulators differentially control nystatin biosynthesis in Streptomyces noursei ATCC 11455. ISBA Meeting 13 2003-11-10 - 2003-11-14
Poster

Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Ellingsen, Trond Erling; Flickinger, Michael. (2003) Metabolic engineering of Bacillus methanolicus for improved L-lysine production. Annual Metting Society for industrial microbiology , Minneapolis 2003-08-10 - 2003-08-14

2002

Academic lecture

Brautaset, Trygve; Bruheim, Per; Sekurova, Olga; Sletta, Håvard; Ellingsen, Trond E.; Strøm, Arne Reidar. (2002) Nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455: mutational analysis, and future perspectives for genetic manipulation. 9th International Symposium on the Genetics of Industrial Microorganisms, , Gjeongju, South Korea 2002-07-05 -

2001

Poster

Zotchev, Sergey; Brautaset, Trygve; Sekurova, Olga; Sletta, Håvard; Fjærvik, E.; Ellingsen, T.E.. (2001) Fremstilling av nye antibiotika ved bruk av genteknologi. Biotek-konferanse , Oslo 2001-06-05 -
Poster

Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Ellingsen, T.E.; Strøm, Arne Reidar; Valla, Svein. (2001) Novel polyene antibiotics via genetic manipulation of the nystatin polyketide synthase. ISBA møte , Vancouver 2001-08-10 -
Poster

Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, Ø.M.; Ellingsen, T.E.. (2001) Analysis of the regulatory locus associated with the nystatin biosynthetic gene cluster in Streptomyces noursei ATCC 11455. ISBA møte , Vancouver 2001-08-10 -
Poster

Brautaset, Trygve; Sekurova, Olga; Sletta, Håvard; Ellingsen, T.E.; Strøm, Arne Reidar; Valla, Svein. (2001) Cloning and analysis of a 125 kb biosynthetic gene cluster for the antibiotic nystatin in Streptomyces noursei. Symposium Biokjemisk Vintermøte , Beitostølen 2001-01-21 -

1998

Academic lecture

Winther-Larsen, Hanne C.; Valand, B.; Blatny, J.M.; Brautaset, Trygve; Valla, Svein. (1998) The Pseudomonas putida Pm promoter system, useful for expression of enzymes in numerous bacterial species. NOS-M seminar for yngre nordiske forskere , Oslo
Academic lecture

Brautaset, Trygve; Petersen, Steffen; Valla, Svein. (1998) Variations in Carbon flow in Escherichia coli as a function of expression level and kinetic constants of the enzyme phosphoglucomutase. Biokjemisk Kontaktmøte 1998 , Lillehammer
Poster

Blatny, Janet-M.; Brautaset, Trygve; Winther-Larsen, Hanne Cecilie; Valla, Svein. (1998) Broad-host-range RK2 vectors useful for cloning of DNA and for high and low regulated gene expression levels in Gram-negative bacteria. NBS Biokjemisk Vintermøte , Lillehammer 1998

1997

Academic lecture

Blatny, Janet Martha; Karunakaran, Ponniah; Brautaset, Trygve; Knutsen, Torill Irene; Winther-Larsen, Hanne C.; Valla, Svein. (1997) New RK2 vectors useful in biotechnology and for analyses of RK2 replication and copy number control. 33. Biokjemiske kontaktmøte , Lillehammer

1996

Poster

Brautaset, Trygve; Petersen, Steffen-B.; Valla, Svein. (1996) Correlation between kinetic constants in vitro and biological effects in vivo of enzyme mutants created by site-directed mutagenesis of phosphoglucomutase from the bacterium Acetobacter xylinum. Priciples, Methods, and Applications of Metabolic Engineering , Boston, USA.
Poster

Brautaset, Trygve; Petersen, Steffen-B.; Ellingsen, Trond; Josefson, Kjell; Valla, Svein. (1996) Protein engineering on the Acetobacter xylinum phosphoglucomutase. NBS Biokjemisk vintermøte , Lillehammer, Januar

1995

Poster

Brautaset, Trygve; Petersen, Steffen-B.; Ellingsen, Trond; Josefson, Kjell; Valla, Svein. (1995) Protein engineering on the Acetobacter xylinum phosphoglucomutase. Carbohydrate engineering meeting , Danmark, 1995

1994

Poster

Brautaset, Trygve; Blatny, Janet-M.; Standal, Rune; Fjærvik, Espen; Valla, Svein. (1994) Development of a model system for use in metaboloc engineering. NBS Biokjemisk Vintermøte , Beitostølen, Januar

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Trygve Brautaset

Trygve Brautaset

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