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Nur Mahammad

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Nur Mahammad

Head Engineer/HSE-Coordinator
Department of Biology
Faculty of Natural Sciences
Department of Biomedical Laboratory Science

nurm@ntnu.no
+4748341072 232.02.046 230 Laboratoriesentret Øya, Trondheim & Realfagbygget, DU1-172, Gløshaugen, Trondheim
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About Publications

About

CV

I am currently working as a Head Engineer in the Department of Biology (IBI) and Head Engineer/HSE-Coordinator in the Department of Biomedical Laboratory Science (IBF) at the Norwegian University of Science and Technology (NTNU). I completed my Ph.D. in Medical Technology at NTNU in collaboration with Coegin Pharma, where I contributed to the development of therapeutic targets for chronic disorders, including cancer.

I completed my Bachelor's and Master's degrees in Genetic Engineering and Biotechnology from the University of Chittagong, Bangladesh, in 2011 and began my research career as a Research Officer at icddr,b in 2012. In 2013, I obtained the Norwegian Government Fellowship (Quota Scheme) to pursue a second master’s degree in Molecular Medicine at NTNU, which I completed in 2015. Subsequently, I joined Coegin Pharma (formerly Avexxin AS) as a Laboratory Engineer in early 2016.

Throughout my research career, I have been fortunate to receive prestigious fellowships, including the MEXT (文部科学省, Monbu-kagaku-shō) fellowship for an internship at the National Institute for Physiological Sciences (NIPS) in Okazaki, Japan, in 2012, and the DAAD (Deutscher Akademischer Austauschdienst) fellowship for an internship at Friedrich Schiller University Jena, Germany, in 2014.

Publications

Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy

Our findings imply cPLA2α may support cancer by mitigating oxidative stress and inhibiting tumor suppressor expression and suggest that AVX420 has potential for treating acute leukemias and other cancers that are susceptible to oxidative cell death.

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells

Our findings implicate cPLA2α activity in the survival of multiple myeloma cells and support further studies into cPLA2α as a potential target for treating hematological cancers, including multiple myeloma.

cPLA2a Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation

Our data suggest that the anti-psoriatic properties of AVX001 could result from a combination of anti-inflammatory and anti-proliferative effects, probably due to reduced local eicosanoid availability.
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2021

  • Mahammad, Nur; Ashcroft, Felicity; Feuerherm, Astrid Jullumstrø; Elsaadi, Samah; Vandsemb, Esten Nymoen; Børset, Magne. (2021) Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells. Molecules
    Academic article

2020

  • Ashcroft, Felicity; Mahammad, Nur; Flatekvål, Helene Midtun; Feuerherm, Astrid Jullumstrø; Johansen, Berit. (2020) cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation. Biomolecules
    Academic article

Journal publications

  • Mahammad, Nur; Ashcroft, Felicity; Feuerherm, Astrid Jullumstrø; Elsaadi, Samah; Vandsemb, Esten Nymoen; Børset, Magne. (2021) Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells. Molecules
    Academic article
  • Ashcroft, Felicity; Mahammad, Nur; Flatekvål, Helene Midtun; Feuerherm, Astrid Jullumstrø; Johansen, Berit. (2020) cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation. Biomolecules
    Academic article

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