Nathan Robert Scrimgeour
About
Nathan has a 100% position as an engineer at the Department of Circulation and Diagnostic Imaging at NTNU, working primarily between the Cardiac Exercise Research Group (CERG) and the Group of Molecular and Cellular Cardiology (GMCC) labs.
Nathan completed his PhD in 2012 in his hometown at the University of Adelaide, Australia. There he studied the biochemical and biophysical properties of store operated Ca2+ channels. In his time since at NTNU he has applied his skills as a patch clamp electrophysiologist to help to characterise the electrophysiological and Ca2+ handling properties of the heart in exercise and disease animal models.
In addition to patch clamp electrophysiology, Nathan also has technical expertise in cell culture, molecular biology and laboratory animal handling techniques.
Competencies
Publications
2024
-
Røsand, Øystein;
Wang, Jianxiang;
Scrimgeour, Nathan Robert;
Marwarha, Gurdeep Singh Atamjit;
Høydal, Morten Andre.
(2024)
Exosomal Preconditioning of Human iPSC-Derived Cardiomyocytes Beneficially Alters Cardiac Electrophysiology and Micro RNA Expression.
International Journal of Molecular Sciences
Academic article
2023
-
Norevik, Cecilie Skarstad;
Huuha, Aleksi Matias;
Røsbjørgen, Ragnhild;
Bergersen, Linda Hildegard;
Jacobsen, Kamilla;
Miguel dos Santos, Rodrigo .
(2023)
Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain.
Journal of Sport and Health Science
Academic article
-
Starheim, Eirin Johannessen;
Ravlo, Erlend;
Schjølberg, Jørn-Ove;
Solvang, Vanessa;
Wang, Wei;
Scrimgeour, Nathan Robert.
(2023)
NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA.
Scientific Reports
Academic article
2022
-
Huuha, Aleksi Matias;
Norevik, Cecilie Skarstad;
Moreira, Jose Bianco Nascimento;
Kobro-Flatmoen, Asgeir;
Scrimgeour, Nathan Robert;
Kivipelto, Miia.
(2022)
Can exercise training teach us how to treat Alzheimer's disease?.
Ageing Research Reviews
Academic literature review
-
Aakerøy, Lars;
Cheng, Chew W.;
Sustova, Pavla;
Scrimgeour, Nathan Robert;
Wahl, Sissel Gyrid Freim;
Steinshamn, Sigurd Loe.
(2022)
Identification of exercise-regulated genes in mice exposed to cigarette smoke.
Physiological Reports
Academic article
-
Marwarha, Gurdeep Singh Atamjit;
Pinho, Maria;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Wahba, Alexander;
Røsbjørgen, Ragnhild.
(2022)
Loss of the protein disrupted in schizophrenia 1 (DISC1) impairs cardiac resistance against ischemia.
bioRxiv
Academic article
2021
-
Marwarha, Gurdeep;
Røsand, Øystein;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Høydal, Morten.
(2021)
miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner.
Biomedicines
Academic article
2020
-
Stølen, Tomas;
Høydal, Morten;
Ahmed, Muhammad Shakil;
Jørgensen, Kari;
Garten, Karin;
Hortigon-Vinagre, Maria.
(2020)
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction.
Journal of Molecular and Cellular Cardiology
Academic article
2019
-
Scrimgeour, Nathan Robert;
Wrobel, Aleksandra Zofia;
Pinho, Maria;
Høydal, Morten.
(2019)
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
American Journal of Physiology - Cell Physiology
Academic article
-
Tari, Atefe R;
Norevik, Cecilie Skarstad;
Scrimgeour, Nathan Robert;
Kobro-Flatmoen, Asgeir;
Storm-Mathisen, Jon;
Bergersen, Linda Hildegard.
(2019)
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?.
Progress in cardiovascular diseases
Academic literature review
2017
-
Pinho, Maria;
Scrimgeour, Nathan Robert;
Stølen, Tomas;
Garten, Karin;
Sharma, Animesh;
Fonseca, Davi de Miranda.
(2017)
Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes.
European Heart Journal
Abstract
-
Scrimgeour, Nathan Robert;
Pinho, Maria;
Wrobel, Aleksandra Zofia;
Høydal, Morten.
(2017)
MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes.
European Heart Journal
Abstract
Journal publications
-
Røsand, Øystein;
Wang, Jianxiang;
Scrimgeour, Nathan Robert;
Marwarha, Gurdeep Singh Atamjit;
Høydal, Morten Andre.
(2024)
Exosomal Preconditioning of Human iPSC-Derived Cardiomyocytes Beneficially Alters Cardiac Electrophysiology and Micro RNA Expression.
International Journal of Molecular Sciences
Academic article
-
Norevik, Cecilie Skarstad;
Huuha, Aleksi Matias;
Røsbjørgen, Ragnhild;
Bergersen, Linda Hildegard;
Jacobsen, Kamilla;
Miguel dos Santos, Rodrigo .
(2023)
Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain.
Journal of Sport and Health Science
Academic article
-
Starheim, Eirin Johannessen;
Ravlo, Erlend;
Schjølberg, Jørn-Ove;
Solvang, Vanessa;
Wang, Wei;
Scrimgeour, Nathan Robert.
(2023)
NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA.
Scientific Reports
Academic article
-
Huuha, Aleksi Matias;
Norevik, Cecilie Skarstad;
Moreira, Jose Bianco Nascimento;
Kobro-Flatmoen, Asgeir;
Scrimgeour, Nathan Robert;
Kivipelto, Miia.
(2022)
Can exercise training teach us how to treat Alzheimer's disease?.
Ageing Research Reviews
Academic literature review
-
Aakerøy, Lars;
Cheng, Chew W.;
Sustova, Pavla;
Scrimgeour, Nathan Robert;
Wahl, Sissel Gyrid Freim;
Steinshamn, Sigurd Loe.
(2022)
Identification of exercise-regulated genes in mice exposed to cigarette smoke.
Physiological Reports
Academic article
-
Marwarha, Gurdeep Singh Atamjit;
Pinho, Maria;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Wahba, Alexander;
Røsbjørgen, Ragnhild.
(2022)
Loss of the protein disrupted in schizophrenia 1 (DISC1) impairs cardiac resistance against ischemia.
bioRxiv
Academic article
-
Marwarha, Gurdeep;
Røsand, Øystein;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Høydal, Morten.
(2021)
miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner.
Biomedicines
Academic article
-
Stølen, Tomas;
Høydal, Morten;
Ahmed, Muhammad Shakil;
Jørgensen, Kari;
Garten, Karin;
Hortigon-Vinagre, Maria.
(2020)
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction.
Journal of Molecular and Cellular Cardiology
Academic article
-
Scrimgeour, Nathan Robert;
Wrobel, Aleksandra Zofia;
Pinho, Maria;
Høydal, Morten.
(2019)
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
American Journal of Physiology - Cell Physiology
Academic article
-
Tari, Atefe R;
Norevik, Cecilie Skarstad;
Scrimgeour, Nathan Robert;
Kobro-Flatmoen, Asgeir;
Storm-Mathisen, Jon;
Bergersen, Linda Hildegard.
(2019)
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?.
Progress in cardiovascular diseases
Academic literature review
-
Pinho, Maria;
Scrimgeour, Nathan Robert;
Stølen, Tomas;
Garten, Karin;
Sharma, Animesh;
Fonseca, Davi de Miranda.
(2017)
Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes.
European Heart Journal
Abstract
-
Scrimgeour, Nathan Robert;
Pinho, Maria;
Wrobel, Aleksandra Zofia;
Høydal, Morten.
(2017)
MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes.
European Heart Journal
Abstract
Knowledge Transfer
2017
-
PosterLjones, Kristine; Ness, Henning Ofstad; Scrimgeour, Nathan Robert; Høydal, Morten. (2017) An acute bout of exhaustive endurance exercise induces upregulation of transcripts encoding calcium handling proteins in the right ventricle. 15th Annual CHFR Symposium on Heart Failure 2017-09-20 - 2017-09-22