Matteo Sangermani
About
Matteo Sangermani is a Researcher at the HUNT Center for Molecular and Clinical Epidemiology (ISM Dep.) in Guro F. Giskeødegård's Molecular Cancer Research Group. Matteo has a PhD in Biophysics (University of Basel) and is with large studies on gut microbiome. He investigates how the gut microbiome is influenced by lifestyle, how changes in the gut microbiome influence the recovery of breast cancer patients and post-treatment quality of life. In the wetlab he is employing a variety of methodsto acquire data from stool samples and blood; such as: shotgun sequencing, 16S rRNA amplicon sequencing, metatranscriptomics, and NMR metabolomics. These multi-omic dataset is then analysed for correlation and prediction modelling. The research goal is to gain insights on how and to which degree changes at one level (e.g. composition) correlates with changes at another levels of the microbiome activity (e.g. gene expression or metabolites), and explore how changes (over time, within and between individuals) correlates with treatment of cancer.
Journal Pubblications: see full list on ORCID
Sangermani M; Hug I; Sauter N; Pfohl T and Jenal U - (2019) - Tad pili play a dynamic role in Caulobacter crescentus surface colonization. - MBio, 10(3). - doi: 10.1128/mBio.01237-19
Laventie BJ ; Sangermani M; et al. - (2019) - A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa. - Cell Host Microbe, 25(1) - doi: 10.1016/j.chom.2018.11.008
Rossmann F; Hug I; Sangermani M; Jenal U and Beeby M - (2020) - In situ structure of the Caulobacter crescentus flagellar motor and visualization of binding of a CheY-homolog. - Molecular Microbiology 114:443–453. - doi: 10.1111/mmi.14525
Sprecher KS; Hug I; Nesper J; Potthoff E; Mahi MA; Sangermani M; Kaever V; Schwede T; Vorholt J; Jenal U. (2017) - Cohesive properties of the Caulobacter crescentus holdfast adhesin are regulated by a novel c-di-GMP effector protein. - MBio, 8(2). - doi: 10.1128/mBio.00294-17
Debik J; Sangermani M; Wang F; Madssen TF; Giskeødegård GF - (2021) - Multivariate analysis of NMR-based metabolomic data. - NMR in Biomedicine - doi: 10.1002/nbm.4638
Grant: (2020 - 2022) Postdoc.Mobility 2020, from Swiss National Fundation (194492)
Grant: (2023 - 2026) Samarbeidsorganet 2023 - Researcher from Helse Midt-Norge (2023-34191)
Competencies
Research
Publications
2022
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Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Academic article
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Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Academic article
Journal publications
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Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Academic article
-
Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Academic article
Knowledge Transfer
2024
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2024) Effect of Repeated Freeze-Thaw Cycles on Fecal-Microbiome Profile. National network of breast cancer research Nasjonalt Nettverk for Brystkreftforskning Nettverksmøte , Tromsø 2024-03-09 - 2024-03-11
2023
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2023) Unraveling the gut microbiome: A metagenomic longitudinal study on composition, diversity, and dynamics. Nordic metabolomic society 3rd Nordic Metabolomics Conferance , Trondheim 2023-10-18 - 2023-10-20
2022
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Academic lectureGiskeødegård, Guro F.; Madssen, Torfinn Støve; Sangermani, Matteo; Lundgren, Steinar; Wethal, Torgeir; Andreassen, Trygve. (2022) Longitudinal modelling reveals distinct changes in circulating metabolites and lipoprotein subfractions after breast cancer treatment. The Metabolomics Society 18th International Conference of the Metabolomics Society, , Valencia 2022-06-19 - 2022-06-23