Rahmi Lale
+4748276019
Kjemi 3, 3.328, Gløshaugen
About
Research
I am leading an interdisciplinary lab operating within the fields of biophysics, computational and synthetic biology. Our main focus is both understanding and controlling transcriptional and translational processes in microorganisms. We employ a range of methods, including microfluidics, single-cell arrays, and high-throughput screening. We work with a wide range of microorganisms, such as Chlamydomonas reinhardtii (chloroplast), Corynebacterium glutamicum, Escherichia coli, Pseudomonas putida KT2440, psychrophilic Pseudomonas, Psychrobacter spp., Pichia pastoris, Streptomyces albus, S. coelicolor, S. lividans, Synechococcus sp. PCC 7002, Saccharomyces cerevisiae, Vibrio natriegens and Thermus thermophilus.
Ongoing Projects
- U.S. National Science Foundation – Global Centers: CIRCLE Center for Innovative Recycling and Circular Economy. Project partner
- EuroHPC, EU (EHPC-AI-2024A02-042) – Expanding AI-based DNA Design Platform to all Domains of Life. Project leader
- Horizon Europe, EU – Targeting aquatic extremophiles for sourcing novel enzymes, drugs, metabolites and chemicals. Project partner
- Horizon Europe, EU – Innovative Tools for Sustainable Exploration of Marine Microbiomes: Towards A Circular Blue Bioeconomy and Healthier Marine Environments. Project partner
- Horizon Europe, EU - From solar energy to fuel: A holistic artificial photosynthesis platform for the production of viable solar fuels. Project partner
- The Research Council of Norway-Enabling Technologies, Norway – SafePhaeO3: Data-driven engineering of microalgal biofactories for safe and efficient omega-3 production. Project partner
- The Research Council of Norway-FRIPRO, Norway - An interdisciplinary data-driven approach to resolve sigma-factor-specific promoter dependency in bacteria (SiD). Project leader
- Innovation Fund Denmark-AgriFoodTure, Denmark - Enhancing Growth and Performance of Cultivated Muscle Cells through Targeted Hydrolysis. Project partner
- Digital Life Norway, Innovation Roadmap TA 1 - Value your data. Project leader
Finalised Projects
- EU-H2020 – Advanced toolbox for rapid and cost-effective functional metagenomic screening – microbiology meets microfluidics.
- EU-H2020 – iFermenter - Conversion of forestry sugar residual streams to antimicrobial proteins by intelligent fermentation.
- EPSRC–UK – Design the Future 2: Thinking Soils: Engineered bacteria as computational agents in the design and manufacture of new materials and structures.
- NFR–FORNY2020–NO – Fast-X-Press
- NTNU-Discovery – SUPERAP – fast track for efficient protein production in novel hosts
- RCN-Commercialisation project - Market validation and scale-up efforts for an AI-based solution in DNA design for biomanufacturing. Project leader (Syngens).
- NTNU Enabling Technologies, Biotechnology - Miniaturised Droplet Biotechnology (iDrop). Ph.D. project
- NTNU Enabling Technologies, Biotechnology - A New Enabling Technology Platform for Recombinant Protein Production. Ph.D. project.
- NTNU-Discovery Pilot Project - A key enabling expression platform.
- NTNU-Biotechnology Program, Bluesky Microfinance Project - Protein Expression and Codon Restriction ´A-La-Carte. Co-PI
Lale Lab
For curious minds, more information can be found on our lab website on what we do: Lale Lab
Teaching
- BT3220 (2018 – …) - Advanced Biotechnology
TBT4507 (2013 – …) - Bioinformatics and Statistics and Research Planning, Specialization Course
TBT4508 (2013 – …) - Bioinformatics and Biopolymeric Materials, Specialization Course - TBT4170 (2021) - Biotechnology
TBT4165 (2015 – 2018) - System Biology and Biological Networks
BI2014 (2013) - Molecular Biology
Scientific profile
Scopus
Google Scholar
PubMed
ResearchGate
ORCID
Publications
- 2024
Khan EA, Rûckert-Reed C, Dahiya GS, Tietze L, Fages-Lartaud M, Busche T, Kalinowski J, Shingler V, Lale R. High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA aptamers and Deep Sequencing. Submitted (Pre-print @ bioRxiv)
- 2023
Dahiya GS, Bakken TI, Fages-Lartaud M, Lale R. From Context to Code: Rational De Novo DNA Design and Predicting Cross-Species DNA Functionality Using Deep Learning Transformer Models. Preprint @ bioRxiv
Dannert C, Mardal I, Lale R, Stokke BT, Dias RS. DNA condensation by peptide-conjugated PAMAM dendrimers. Influence of peptide charge. ACS Omega
- 2022
Fages-Lartaud M, Prone W, Mueller Y, Lale R. Method for engineering artificial bidirectional promoters. Submitted (Pre-print availble at Research Square)
Lale R, Tietze L, Fages-Lartaud M, Nesje J, Onsager I, Engelhardt K, Wong CFA, Akan M, Hummel N, Kalinowski J, Rückert C, Hohmann-Marriott MF. A universal approach to gene expression engineering. OUP Synthetic Biology.
Fages-Lartaud M, Tietze L, Elie F, Lale R, Hohmann-Marriott MF. mCherry contains a fluorescent protein isoform that interferes with its reporter function. Frontiers in Bioengineering and Biotechnology - Synthetic Biology.
Tietze L, Mangold A, Hoff M, Lale R. Identification and cross-characterisation of artificial promoters and 5' untranslated regions in Vibrio natriegens. Frontiers in Bioengineering and Biotechnology - Synthetic Biology.
- 2021
Wong CFA, van Vliet L, Bhujbal SV, Guo C, Sletmoen M, Stokke BT, Hollfelder F, Lale R. A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalised Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution. ACS Synthetic Biology
Tietze L, Lale R. Importance of the 5′ Regulatory Region to Bacterial Synthetic Biology Applications. Microbial Biotechnology
- 2020
Bhujbal SV, Dekov M, Ottesen V, Dunker K, Lale R, Sletmoen M. Effect of design geometry, exposure energy, cytophilic molecules, cell type and load in fabrication of single-cell arrays using micro-contact printing. Scientific Reports.
Le SB, Onsager I, Lorentzen JA, Lale R. Dual UTR–A novel 5' untranslated region design for synthetic biology applications. OUP Synthetic Biology.
- 2019
Le SB, Onsager I, Lorentzen JA, Lale R. Dual UTR–A novel 5' untranslated region design for synthetic biology applications. Preprint at bioRxiv.
Lale R, Tietze L, Nesje J, Onsager I, Engelhardt K, Wong CFA, Akan M, Hummel N, Kalinowski J, Rückert C, Hohmann-Marriott MF. A universal method for gene expression engineering. Submitted (Preprint available at bioRxiv).
Moghadam MM, Tietze L, Wentzel A, Lale R. Biochemical Characterization of Three Laccase-Like Multicopper Oxidases from Arctic Marine Psychrobacter spp. Submitted.
- 2018
Schneider O, Simic N, Aachmann F, Rückert C, Kristiansen K, Kalinowski J, Jiang Y, Wang L, Jiang C, Lale R, Zotchev S. Genome Mining of Streptomyces sp. YIM 130001 Isolated from Lichen Affords New Thiopeptide Antibiotic. Front Microbiol.
- 2017
Ramisetty SK, Langlette P, Lale R, Dias RdS. In vitro studies of DNA condensation by bridging protein in a crowding environment. International Journal of Biological Macromolecules.
Vogel AIM, Lale R, Hohmann-Marriott MF. Streamlining recombination-mediated genetic engineering by validating three neutral integration sites in Synechococcus sp. PCC 7002. Journal of Biological Engineering.
Lewin A, Lale R, Wentzel A. Expression Platforms for Functional Metagenomics – Emerging technology options beyond Escherichia coli. Functional Metagenomics: Tools and Applications. Springer.
- 2016
Beal J, Haddock-Angelli T, Gershater M, de Mora K, Lizarazo M, Hollenhorst J, et al. Reproducibility of fluorescent expression from engineered biological constructs in E. coli. PLoS ONE.
Arnfinnsdottir, NB., Bjørkøy, A., Lale, R., Sletmoen, M. Heterogeneity in GFP expression in isogenic populations of P. putida KT2440 investigated using flow cytometry and bacterial microarrays. RSC Advances
Moghadam MM, Albersmeier A,Winkler A, Cimmino L, Rise K, Hohmann-Marriott FM, Kalinowski J, Rückert C, Wentzel A, Lale, R. Isolation and genome sequencing of four Arctic marine Psychrobacter strains exhibiting multicopper oxidase activity. BMC Genomics.
- 2015
Bjerga, GE, Lale, R., Williamson, A. Engineering low-temperature expression systems for heterologous expression of cold-adapted enzymes. Bioengineered
Arnfinnsdottir, NB., Ottesen, V., Lale, R., Sletmoen, M. The design of simple bacterial microarrays. Development towards immobilizing single living bacteria on predefined micro-sized spots on patterned surfaces. PLoS ONE.
- 2014
Petrov, V., Balasubramaniam, S., Lale, R., Moltchanov, D., Lio’, P., Koucheryavy, Y. Forward and Reverse Coding for Chromosome Transfer in Bacterial Nanonetworks. Nano Communication Networks.
Strand, TA., Lale, R., Degnes, KF., Lando, M. and Valla, S. A new and improved host-independent plasmid system for RK2-based conjugal transfer. PLoS ONE.
DNA Cloning and Assembly Methods. Methods in Molecular Biology, editors Rahmi Lale and Svein Valla. Volume 1116, XI, 303 p. Springer Protocols, Humana Press.
Røkke, G., Korvald, E., Pahr, J., Øyås, O., and Lale, R. BioBrick assembly standards and techniques and associated software tools. DNA Cloning and Assembly Methods. Methods in Molecular Biology, editors Lale, R. and Valla, S. Volume 1116, 2014, pp 1-24 Springer Protocols, Humana Press.
- 2013
Zwick, F., Lale, R. and Valla, S. Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pm promoter. BMC Microbiol. 13: 262
Zwick, F., Lale, R. and Valla, S. Combinatorial engineering for heterologous gene expression. Bioengineered.
Balzer, S., Kucharova, V., Megerle, J., Lale, R., Brautaset, T., Valla, S. A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli. Microbial Cell Factories, 12:26.
- 2012
Zwick, F., Lale, R. and Valla, S. Strong stimulation of recombinant protein production in Escherichia coli by combining stimulatory expression control elements in the expression cassette. Microbial Cell Factories, 11:133.
Almaas, E., Bruheim, P., Lale, R. and Valla, S. Dynamics and robustness of metabolic networks: A systems biology review of Escherichia coli metabolism. Systems Microbiology: Current Topics and Applications. ISBN: 978-1-908230-02-7.
- 2011
Aakvik, T., Lale, R., Liles, M. and Valla, S. Metagenomic libraries for functional screening, Ch 22. Handbook of Molecular Microbial Ecology I: Metagenomics and Complementary Approaches. Ed. de Bruijn, F.J.
Lale, R., Brautaset, T.and Valla, S. Broad-host-range plasmid vectors for gene expression in bacteria. Met. Mol. Biol. 765, Part 3, 327-343.
Lale, R., Berg, L., Stüttgen, F., Netzer, R., Stafsnes, M., Brautaset, T., Aune, T.E.V. and Valla. S. Continuous control of the flow in biochemical pathways through 5'-UTR sequence modifications in mRNA expressed from the broad-host-range Pm promoter. Appl. Env. Mircobiol. 77: 2648-2655.
- 2010
Aune, T. E. V., Bakke, I., Drabløs, F., Lale, R., Brautaset, T. and Valla, S. Directed evolution of the transcription factor XylS for development of improved expression systems. Microb. Biotechnol. 3:1, 38–47.
- 2009
Berg, L., Lale, R., Bakke, I., Burroughs, N. and Valla, S. The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA. Microb. Biotechnol. 2(3), 379-389.
Brautaset, T., Lale, R. and Valla, S. Positively regulated bacterial expression systems. Microb. Biotechnol. 2 (1), 15-30.
- 2008
Bar, N. S. and Lale, R. Modeling and control of the protein synthesis process in eukaryotic cells. 47th IEEE Proceedings: Conference on Decision and Control (CDC) 179-184.
Competencies
Research
Publications
2023
-
Dahiya, Gurvinder;
Baken, Thea Isabel;
Fages-Lartaud, Maxime René;
Lale, Rahmi.
(2023)
From Context to Code: Rational De Novo DNA Design and Predicting Cross-Species DNA Functionality Using Deep Learning Transformer Models.
bioRxiv
Academic article
-
Dannert, Corinna;
Mardal, Ingrid;
Lale, Rahmi;
Stokke, Bjørn Torger;
Dias, Rita.
(2023)
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers. Influence of Peptide Charge.
ACS Omega
Academic article
2022
-
Tietze, Lisa;
Mangold, Antonia;
Hoff, Maria Wilhelmsen;
Lale, Rahmi.
(2022)
Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Fages-Lartaud, Maxime René;
Tietze, Lisa;
Elie, Florence;
Lale, Rahmi;
Hohmann-Marriott, Martin Frank.
(2022)
mCherry contains a fluorescent protein isoform that interferes with its reporter function.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Lale, Rahmi;
Tietze, Lisa;
Fages-Lartaud, Maxime René;
Nesje, Jenny;
Onsager, Ingerid;
Engelhardt, Kerstin.
(2022)
A universal approach to gene expression engineering.
Synthetic Biology
Academic article
2021
-
Wong, Che Fai Alex;
van Vliet, Liisa;
Bhujbal, Swapnil Vilas;
Guo, Chengzhi;
Sletmoen, Marit;
Stokke, Bjørn Torger.
(2021)
A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalised Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution.
ACS Synthetic Biology
Academic article
-
Tietze, Lisa;
Lale, Rahmi.
(2021)
Importance of the 5′ regulatory region to bacterial synthetic biology applications.
Microbial Biotechnology
Academic literature review
-
Oakes, kelly;
Lale, Rahmi.
(2021)
A new way to get cells to spill their secrets .
Norwegian SciTech News
Popular scientific article
2020
-
Bhujbal, Swapnil Vilas;
Dekov, Maren;
Ottesen, Vegar;
Dunker, Karen;
Lale, Rahmi;
Sletmoen, Marit.
(2020)
Effect of design geometry, exposure energy, cytophilic molecules, cell type and load in fabrication of single-cell arrays using micro-contact printing.
Scientific Reports
Academic article
-
Le, Simone Balzer;
Onsager, Ingerid;
Lorentzen, Jon Andreas;
Lale, Rahmi.
(2020)
Dual UTR-A novel 5′ untranslated region design for synthetic biology applications.
Synthetic Biology
Academic article
2019
-
Lale, Rahmi;
Tietze, Lisa;
Nesje, Jenny;
Onsager, Ingerid;
Engelhardt, Kerstin;
Wong, Che Fai Alex.
(2019)
A universal method for gene expression engineering.
bioRxiv
Academic article
-
Lale, Rahmi;
Wentzel, Alexander.
(2019)
Functional Metagenomics 2019
http://www.fmg2019.net/.
Website (informational material)
-
Halsne, Ruth;
Lale, Rahmi.
(2019)
Bakterier med syntetisk genom.
Tidsskrift for Den norske legeforening
Popular scientific article
2018
-
Schneider, Olha;
Simic, Nebojsa;
Aachmann, Finn Lillelund;
Rückert, Christian;
Kristiansen, Kåre Andre;
Kalinowski, Jörn.
(2018)
Genome Mining of Streptomyces sp. YIM 130001 Isolated From Lichen Affords New Thiopeptide Antibiotic.
Frontiers in Microbiology
Academic article
-
Lale, Rahmi.
(2018)
Kavliprisen i nanovitenskap.
Fra Fysikkens Verden
Popular scientific article
2017
-
Vogel, Anne Ilse Maria;
Lale, Rahmi;
Hohmann-Marriott, Martin Frank.
(2017)
Streamlining recombination-mediated genetic engineering by validating three neutral integration sites in Synechococcus sp. PCC 7002.
Journal of Biological Engineering
Academic article
-
Ramisetty, Sravani Keerthi;
Langlete, Petter;
Lale, Rahmi;
Dias, Rita de Sousa.
(2017)
In vitro studies of DNA condensation by bridging protein in a crowding environment.
International Journal of Biological Macromolecules
Academic article
2016
-
Beal, J, et al.;
Lale, Rahmi.
(2016)
Reproducibility of fluorescent expression from engineered biological constructs in E. coli.
PLOS ONE
Academic article
-
Shojaei Moghadam, Morteza;
Albersmeier, Andreas;
Winkler, Anika;
Cimmino, Lorenzo;
Rise, Kjersti;
Hohmann-Marriott, Martin Frank.
(2016)
Isolation and genome sequencing of four Arctic marine Psychrobacter strains exhibiting multicopper oxidase activity.
BMC Genomics
Academic article
-
Arnfinnsdottir, Nina Bjørk;
Bjørkøy, Astrid;
Lale, Rahmi;
Sletmoen, Marit.
(2016)
Heterogeneity in GFP expression in isogenic populations of P. putida KT2440 investigated using flow cytometry and bacterial microarrays .
RSC Advances
Academic article
-
Bjerga, Gro Elin Kjæreng;
Lale, Rahmi;
Williamson, Adele Kim.
(2016)
Engineering low-temperature expression systems for heterologous production of cold-adapted enzymes.
Bioengineered
Academic article
2015
-
Arnfinnsdottir, Nina Bjørk;
Ottesen, Vegar;
Lale, Rahmi;
Sletmoen, Marit.
(2015)
The Design of Simple Bacterial Microarrays: Development towards Immobilizing Single Living Bacteria on Predefined Micro-Sized Spots on Patterned Surfaces.
PLOS ONE
Academic article
2014
-
Røkke, Gunvor;
Korvald, Eirin;
Pahr, Jarle;
Øyås, Ove;
Lale, Rahmi.
(2014)
BioBrick Assembly Standards and Techniques and Associated Software Tools.
Humana Press
Academic chapter/article/Conference paper
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
Only two days away from the competition.
Website (informational material)
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
We won the gold medal at the iGEM competiton.
Website (informational material)
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
Competing in Synthetic biology.
Website (informational material)
-
Petrov, Vitaly;
Balasubramaniam, Sasitharan;
Lale, Rahmi;
Moltchanov, Dmitri;
Liò, Pietro;
Koucheryavy, Yevgeni.
(2014)
Forward and Reverse coding for chromosome transfer in bacterial nanonetworks.
Nano Communication Networks
Academic article
-
Valla, Svein;
Lale, Rahmi.
(2014)
DNA Cloning and Assembly Methods.
Humana Press
Methods in molecular biology (1116)
Academic anthology/Conference proceedings
-
Aakvik, Trine;
Lale, Rahmi;
Degnes, Kristin Fløgstad;
Lando, Malin;
Valla, Svein.
(2014)
A new and improved host-independent plasmid system for RK2-based conjugal transfer.
PLOS ONE
Academic article
2013
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2013)
Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pm promoter.
BMC Microbiology
Academic article
-
Balzer, Simone;
Kucharova, Veronika;
Megerle, Judith;
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2013)
A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli.
Microbial Cell Factories
Academic article
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2013)
Combinatorial engineering for heterologous gene expression.
Bioengineered Bugs
Academic article
2012
-
Almaas, Eivind;
Bruheim, Per;
Lale, Rahmi;
Valla, Svein.
(2012)
Dynamics and robustness of metabolic networks: A systems biology review of Escherichia coli metabolism.
Caister Academic Press
Academic chapter/article/Conference paper
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2012)
Strong stimulation of recombinant protein production in Escherichia coli by combining stimulatory control elements in an expression cassette.
Microbial Cell Factories
Academic article
2011
-
Aakvik, Trine;
Lale, Rahmi;
Liles, Mark R.;
Valla, Svein.
(2011)
Metagenomic Libraries for Functional Screening.
Wiley-Blackwell
Academic chapter/article/Conference paper
-
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2011)
Broad-Host-Range Plasmid Vectors for Gene Expression in Bacteria.
Springer Science+Business Media B.V.
Academic chapter/article/Conference paper
-
Lale, Rahmi;
Berg, Laila;
Stuttgen, Friederike;
Netzer, Roman;
Stafsnes, Marit Hallvardsdotter;
Brautaset, Trygve.
(2011)
Continuous Control of the Flow in Biochemical Pathways through 5 ' Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm.
Applied and Environmental Microbiology
Academic article
2010
-
Aune, Trond Erik Vee;
Bakke, Ingrid;
Drabløs, Finn;
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2010)
Directed evolution of the transcription factor XylS for development of improved expression systems.
Microbial Biotechnology
Academic article
2009
-
Brautaset, Trygve;
Lale, Rahmi;
Valla, Svein.
(2009)
Minireview - Positively regulated bacterial expression systems.
Microbial Biotechnology
Academic article
-
Berg, Laila;
Lale, Rahmi;
Bakke, Ingrid;
Burroughs, Nigel;
Valla, Svein.
(2009)
The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA.
Microbial Biotechnology
Academic article
-
Lale, Rahmi.
(2009)
The xylS/Pm expression cassette: New functional insights and application potentials.
Institutt for bioteknologi, NTNU
Doctoral dissertation
2008
-
Bar, Nadav;
Lale, Rahmi.
(2008)
Modeling and Control of the Protein Synthesis process in Eukaryotic cells.
Proceedings of the IEEE Conference on Decision & Control, including the Symposium on Adaptive Processes
Academic article
Journal publications
-
Dahiya, Gurvinder;
Baken, Thea Isabel;
Fages-Lartaud, Maxime René;
Lale, Rahmi.
(2023)
From Context to Code: Rational De Novo DNA Design and Predicting Cross-Species DNA Functionality Using Deep Learning Transformer Models.
bioRxiv
Academic article
-
Dannert, Corinna;
Mardal, Ingrid;
Lale, Rahmi;
Stokke, Bjørn Torger;
Dias, Rita.
(2023)
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers. Influence of Peptide Charge.
ACS Omega
Academic article
-
Tietze, Lisa;
Mangold, Antonia;
Hoff, Maria Wilhelmsen;
Lale, Rahmi.
(2022)
Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Fages-Lartaud, Maxime René;
Tietze, Lisa;
Elie, Florence;
Lale, Rahmi;
Hohmann-Marriott, Martin Frank.
(2022)
mCherry contains a fluorescent protein isoform that interferes with its reporter function.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Lale, Rahmi;
Tietze, Lisa;
Fages-Lartaud, Maxime René;
Nesje, Jenny;
Onsager, Ingerid;
Engelhardt, Kerstin.
(2022)
A universal approach to gene expression engineering.
Synthetic Biology
Academic article
-
Wong, Che Fai Alex;
van Vliet, Liisa;
Bhujbal, Swapnil Vilas;
Guo, Chengzhi;
Sletmoen, Marit;
Stokke, Bjørn Torger.
(2021)
A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalised Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution.
ACS Synthetic Biology
Academic article
-
Tietze, Lisa;
Lale, Rahmi.
(2021)
Importance of the 5′ regulatory region to bacterial synthetic biology applications.
Microbial Biotechnology
Academic literature review
-
Oakes, kelly;
Lale, Rahmi.
(2021)
A new way to get cells to spill their secrets .
Norwegian SciTech News
Popular scientific article
-
Bhujbal, Swapnil Vilas;
Dekov, Maren;
Ottesen, Vegar;
Dunker, Karen;
Lale, Rahmi;
Sletmoen, Marit.
(2020)
Effect of design geometry, exposure energy, cytophilic molecules, cell type and load in fabrication of single-cell arrays using micro-contact printing.
Scientific Reports
Academic article
-
Le, Simone Balzer;
Onsager, Ingerid;
Lorentzen, Jon Andreas;
Lale, Rahmi.
(2020)
Dual UTR-A novel 5′ untranslated region design for synthetic biology applications.
Synthetic Biology
Academic article
-
Lale, Rahmi;
Tietze, Lisa;
Nesje, Jenny;
Onsager, Ingerid;
Engelhardt, Kerstin;
Wong, Che Fai Alex.
(2019)
A universal method for gene expression engineering.
bioRxiv
Academic article
-
Halsne, Ruth;
Lale, Rahmi.
(2019)
Bakterier med syntetisk genom.
Tidsskrift for Den norske legeforening
Popular scientific article
-
Schneider, Olha;
Simic, Nebojsa;
Aachmann, Finn Lillelund;
Rückert, Christian;
Kristiansen, Kåre Andre;
Kalinowski, Jörn.
(2018)
Genome Mining of Streptomyces sp. YIM 130001 Isolated From Lichen Affords New Thiopeptide Antibiotic.
Frontiers in Microbiology
Academic article
-
Lale, Rahmi.
(2018)
Kavliprisen i nanovitenskap.
Fra Fysikkens Verden
Popular scientific article
-
Vogel, Anne Ilse Maria;
Lale, Rahmi;
Hohmann-Marriott, Martin Frank.
(2017)
Streamlining recombination-mediated genetic engineering by validating three neutral integration sites in Synechococcus sp. PCC 7002.
Journal of Biological Engineering
Academic article
-
Ramisetty, Sravani Keerthi;
Langlete, Petter;
Lale, Rahmi;
Dias, Rita de Sousa.
(2017)
In vitro studies of DNA condensation by bridging protein in a crowding environment.
International Journal of Biological Macromolecules
Academic article
-
Beal, J, et al.;
Lale, Rahmi.
(2016)
Reproducibility of fluorescent expression from engineered biological constructs in E. coli.
PLOS ONE
Academic article
-
Shojaei Moghadam, Morteza;
Albersmeier, Andreas;
Winkler, Anika;
Cimmino, Lorenzo;
Rise, Kjersti;
Hohmann-Marriott, Martin Frank.
(2016)
Isolation and genome sequencing of four Arctic marine Psychrobacter strains exhibiting multicopper oxidase activity.
BMC Genomics
Academic article
-
Arnfinnsdottir, Nina Bjørk;
Bjørkøy, Astrid;
Lale, Rahmi;
Sletmoen, Marit.
(2016)
Heterogeneity in GFP expression in isogenic populations of P. putida KT2440 investigated using flow cytometry and bacterial microarrays .
RSC Advances
Academic article
-
Bjerga, Gro Elin Kjæreng;
Lale, Rahmi;
Williamson, Adele Kim.
(2016)
Engineering low-temperature expression systems for heterologous production of cold-adapted enzymes.
Bioengineered
Academic article
-
Arnfinnsdottir, Nina Bjørk;
Ottesen, Vegar;
Lale, Rahmi;
Sletmoen, Marit.
(2015)
The Design of Simple Bacterial Microarrays: Development towards Immobilizing Single Living Bacteria on Predefined Micro-Sized Spots on Patterned Surfaces.
PLOS ONE
Academic article
-
Petrov, Vitaly;
Balasubramaniam, Sasitharan;
Lale, Rahmi;
Moltchanov, Dmitri;
Liò, Pietro;
Koucheryavy, Yevgeni.
(2014)
Forward and Reverse coding for chromosome transfer in bacterial nanonetworks.
Nano Communication Networks
Academic article
-
Aakvik, Trine;
Lale, Rahmi;
Degnes, Kristin Fløgstad;
Lando, Malin;
Valla, Svein.
(2014)
A new and improved host-independent plasmid system for RK2-based conjugal transfer.
PLOS ONE
Academic article
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2013)
Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pm promoter.
BMC Microbiology
Academic article
-
Balzer, Simone;
Kucharova, Veronika;
Megerle, Judith;
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2013)
A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli.
Microbial Cell Factories
Academic article
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2013)
Combinatorial engineering for heterologous gene expression.
Bioengineered Bugs
Academic article
-
Zwick, Friederike;
Lale, Rahmi;
Valla, Svein.
(2012)
Strong stimulation of recombinant protein production in Escherichia coli by combining stimulatory control elements in an expression cassette.
Microbial Cell Factories
Academic article
-
Lale, Rahmi;
Berg, Laila;
Stuttgen, Friederike;
Netzer, Roman;
Stafsnes, Marit Hallvardsdotter;
Brautaset, Trygve.
(2011)
Continuous Control of the Flow in Biochemical Pathways through 5 ' Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm.
Applied and Environmental Microbiology
Academic article
-
Aune, Trond Erik Vee;
Bakke, Ingrid;
Drabløs, Finn;
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2010)
Directed evolution of the transcription factor XylS for development of improved expression systems.
Microbial Biotechnology
Academic article
-
Brautaset, Trygve;
Lale, Rahmi;
Valla, Svein.
(2009)
Minireview - Positively regulated bacterial expression systems.
Microbial Biotechnology
Academic article
-
Berg, Laila;
Lale, Rahmi;
Bakke, Ingrid;
Burroughs, Nigel;
Valla, Svein.
(2009)
The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA.
Microbial Biotechnology
Academic article
-
Bar, Nadav;
Lale, Rahmi.
(2008)
Modeling and Control of the Protein Synthesis process in Eukaryotic cells.
Proceedings of the IEEE Conference on Decision & Control, including the Symposium on Adaptive Processes
Academic article
Books
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Valla, Svein;
Lale, Rahmi.
(2014)
DNA Cloning and Assembly Methods.
Humana Press
Methods in molecular biology (1116)
Academic anthology/Conference proceedings
Part of book/report
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Røkke, Gunvor;
Korvald, Eirin;
Pahr, Jarle;
Øyås, Ove;
Lale, Rahmi.
(2014)
BioBrick Assembly Standards and Techniques and Associated Software Tools.
Humana Press
Academic chapter/article/Conference paper
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Almaas, Eivind;
Bruheim, Per;
Lale, Rahmi;
Valla, Svein.
(2012)
Dynamics and robustness of metabolic networks: A systems biology review of Escherichia coli metabolism.
Caister Academic Press
Academic chapter/article/Conference paper
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Aakvik, Trine;
Lale, Rahmi;
Liles, Mark R.;
Valla, Svein.
(2011)
Metagenomic Libraries for Functional Screening.
Wiley-Blackwell
Academic chapter/article/Conference paper
-
Lale, Rahmi;
Brautaset, Trygve;
Valla, Svein.
(2011)
Broad-Host-Range Plasmid Vectors for Gene Expression in Bacteria.
Springer Science+Business Media B.V.
Academic chapter/article/Conference paper
Report
-
Lale, Rahmi.
(2009)
The xylS/Pm expression cassette: New functional insights and application potentials.
Institutt for bioteknologi, NTNU
Doctoral dissertation
INFORMASJONSMATR
-
Lale, Rahmi;
Wentzel, Alexander.
(2019)
Functional Metagenomics 2019
http://www.fmg2019.net/.
Website (informational material)
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
Only two days away from the competition.
Website (informational material)
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
We won the gold medal at the iGEM competiton.
Website (informational material)
-
Lale, Rahmi;
Drejer, Eivind Bøe;
Hesthammer, Ronja;
Omtvedt, Line;
Lamb, Jacob Joseph;
Røynestad, Pål.
(2014)
Competing in Synthetic biology.
Website (informational material)
Teaching
Courses
Knowledge Transfer
2024
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Academic lectureLale, Rahmi. (2024) High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA aptamers and Deep Sequencing. JCVI, Prof. John Glass 4th Minimal Cell Workshop , Online 2024-09-23 -
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InterviewLale, Rahmi. (2024) Interview with Rahmi Lale, co-founder of the start-up Syngens. https://syntheticcell.eu/interview-with-rahmi-lale-co-founde https://syntheticcell.eu/interview-with-rahmi-lale-co-founde [Internet] 2024-10-21
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Academic lectureLale, Rahmi. (2024) Leveraging AI for Context-Aware and Predictable DNA Design in Synthetic Biology. INSA, Toulouse Biotechnology Institute, Toulouse, France SynCell 2024 - International Conference on Engineering Synthetic Cells and Organelles , Toulouse, France 2024-04-17 - 2024-04-19
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PosterKhan, Essa Ahsan; Lale, Rahmi. (2024) High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA aptamers and Deep Sequencing in Pseudomonas putida. International Biennial Pseudomonas Conference 2024-09-01 - 2024-09-05
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PosterKhan, Essa Ahsan; Rückert-Reed, Christian; Dahiya, Gurvinder Singh; Tietze, Lisa; Fages-Lartaud, Maxime René; Busche, Tobias. (2024) High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA aptamers and Deep Sequencing in Pseudomonas putida. 2024 Synthetic Biology: Engineering, Evolution & Design (SEED) 2024-06-24 - 2024-06-27
2023
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Academic lectureTeigset, Erlend Gløer Stedje; Lale, Rahmi. (2023) Microfluidics and synthetic biology methods for enzyme discovery. Tekna BIOPROSP_23 , Tromsø 2023-03-14 - 2023-03-16
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Academic lectureLale, Rahmi. (2023) An interdisciplinary study of bacterial transcriptional regulation by combining microfluidics, computational and synthetic biology. NBS 58th NBS Contact Meeting , Storefjell, Gol 2023-01-19 - 2023-01-22
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Academic lectureLale, Rahmi. (2023) Leveraging AI for context-aware and predictable DNA design in Synthetic Biology. German Association of Synthetic Biology German Association of Synthetic Biology Conference, 7th. , Freiburg 2023-09-18 - 2023-09-20
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PosterAhmed, Husnain; Khan, Essa Ahsan; Tietze, Lisa; Fages-Lartaud, Maxime; Totlani, Kartik; Bjørkøy, Astrid. (2023) Identification of novel sigma 54 DNA binding sequences using artificial promoters in Pseudomonas putida. NBS Norwegian Biochemical Society (NBS) contact meeting 2023 , Storefjell 2023-01-19 - 2023-01-22
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Academic lectureTotlani, Kartik; Ahmed, Husnain; Ahsan Khan, Essa; Bjørkøy, Astrid; Stokke, Bjørn Torger; Lale, Rahmi. (2023) Droplet-based microfluidics for studying transcriptional regulation in bacteria. SMILS Network SMILS 2023 , Stockholm 2023-05-30 - 2023-05-31
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PosterØvreeide, Ingrid Haga; Szydlak, Renata; Zemla, Joanna; Luty, Marcin; Monaldi, Jessica; Hines, Thomas G.. (2023) Micro- and nanofabrication for biophysics and biomedical research. NTNU Health, NTNU Nano, and NTNU Biotechnology Sensor Day , Trondheim 2023-04-26 - 2023-04-26
2022
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Popular scientific lectureTietze, Lisa; Hoff, Maria Wilhelmsen; Lale, Rahmi. (2022) Using artificial regulatory sequences to express proteins with Vibrio natriegens. NBS Contact meeting 2022-02-10 - 2022-02-13
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Popular scientific lectureLale, Rahmi. (2022) Taking the leap from an AI researcher to an AI founder. NORA NORA.startup event #30: Founding an AI startup as an AI Researcher , Tromsø 2022-04-21 -
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Popular scientific lectureLale, Rahmi. (2022) Lessons learned from commercializing a research driven innovation project. NORA NORA.startup event #30: Founding an AI startup as an AI Researcher , Tromsø 2022-04-21 -
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Programme participationLale, Rahmi. (2022) HSBC Build with Bio – Expert Panel: Can we really „Grow” Everything? Goals and Limits of Synthetic Biology. Online Online [Internet] 2022-03-09
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LectureAhmed, Husnain; Ahsan Khan, Essa; Tietze, Lisa; Fages-Lartaud, Maxime René; Totlani, Kartik; Bjørkøy, Astrid. (2022) Unravelling the sigma factor specific promoter binding in bacterial in-vitro transcription using droplet microfluidics. NTNU TNNN Conference 2022 , Trondheim 2022-11-30 - 2022-12-02
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PosterAhmed, Husnain; Ahsan Khan, Essa; Tietze, Lisa; Fages-Lartaud, Maxime René; Totlani, Kartik; Bjørkøy, Astrid. (2022) Matchmaking inside microdroplets: unravelling the sigma factor specific promoter binding in bacterial in-vitro transcription using droplet microfluidics. EMBL EMBL Microfluidics 2022 , Heidelberg 2022-07-11 - 2022-07-13
2021
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LectureLale, Rahmi. (2021) Gene expression optimisation. ArcticZymes AS Invited lecture , Digital 2021-02-19 -
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LectureLale, Rahmi. (2021) AI and Syngens. Research Council of Norway, NORA.startup, NORA.EU NORA.startup and NORA.EU (EU Network to Horizon Europe on AI) Event , Oslo 2021-10-21 - 2021-10-21
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LectureLale, Rahmi. (2021) Anvendelse av felles europeisk infrastruktur for tungregning. NOKIOS 2021, Plenum 2 . NTNU, Digitaliseringsdirektorat NOKIOS – Norsk konferanse for IKT i offentlig sektor , Trondheim 2021-10-27 - 2021-10-27
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Interview
2020
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Academic lectureLale, Rahmi. (2020) A titratable cell lysis system for intracellular products release from Escherichia coli in microfluidic droplets. Plenary lecture. Kafkas University 9th International Molecular Biology and Biotechnology Congress , Online 2020-12-06 - 2020-12-10
2019
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Academic lectureLale, Rahmi. (2019) Towards rational design of promoters. Invited Presentation. Heinrich Heine University Düsseldorf, Synthetic Microbiology Seminar , Düsseldorf 2019-12-19 - 2019-12-19
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LectureLale, Rahmi. (2019) A novel platform for generating artificial gene expression systems in bacteria and yeast. EMBO EMBO Workshop – Creating is Understanding: Synthetic Biology Masters Complexity , Heidelberg 2019-09-22 - 2019-09-25
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PosterHohmann-Marriott, Martin Frank; Vogel, Anne Ilse Maria; Årstøl, Erland; Lale, Rahmi. (2019) Identification of the siderophore biosynthesis operon of Synechococcus sp. PCC 7002. University of Colorado-Boulder 13thWorkshop on Cyanobacteria , Boulder 2019-06-06 - 2019-06-09
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PosterÅrstøl, Erland; Vogel, Anne Ilse Maria; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2019) Molecular insights into the siderophore biosynthesis of Synechococcus PCC 7002. 14th Nordic photosynthesis Congress 2019-05-24 - 2019-05-27
2018
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PosterBhujbal, Swapnil Vilas; Wong, Che Fai Alex; Sletmoen, Marit; Stokke, Bjørn Torger; Lale, Rahmi. (2018) MetaFluidics: A platform for rapid and cost-effective functional metagenomic screening. Digital Life Norway Digital Life 2018 , Bergen 2018-03-20 - 2018-03-21
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PosterTietze, Lisa; Lale, Rahmi. (2018) The Development of a Universal Synthetic Promoter-5´ UTR Design Platform. Digital Life Norway annual conference 2018-03-20 - 2018-03-21
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PosterVogel, Anne Ilse Maria; Winther-Larsen, Hanne Cecilie; Roos, Norbert; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2018) A novel function of type IV pili in iron uptake in Synechococcus sp. PCC 7002. ISPR ISPR conference on microbial photosynthesis , Vancouver 2018-08-09 - 2018-08-12
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Academic lectureLale, Rahmi. (2018) Expanding the Synthetic Biology Toolbox: An overview of the tools designed at PhotoSynLab. Invited Presentation. University of Bremen Synthetic Biology Conference in Bremen , Bremen 2018-10-11 - 2018-10-12
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PosterVogel, Anne Ilse Maria; Winther-Larsen, Hanne Cecilie; Roos, Norbert; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2018) Function of type IV pili in iron acquisition in Synechococcus sp. PCC 7002. Rui Miao and Michael Cheah ePS-Young meeting , Uppsala 2018-06-24 - 2018-06-25
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Academic lectureVogel, Anne Ilse Maria; Winther-Larsen, Hanne Cecilie; Roos, Norbert; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2018) Function of type IV pili in iron acquisition in Synechococcus sp. PCC 7002. Rui Miao and Michael Cheah ePS-Young meeting , Uppsala 2018-06-24 -
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PosterVogel, Anne Ilse Maria; Winther-Larsen, Hanne Cecilie; Roos, Norbert; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2018) Function of type IV pili in iron acquisition in Synechococcus sp. PCC 7002. ISPR/SPPS ePS-1 , Uppsala 2018-06-25 - 2018-06-28
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PosterVogel, Anne Ilse Maria; Winther-Larsen, Hanne Cecilie; Roos, Norbert; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2018) Conductive Type IV pili play an important role for iron acquisition in the marine cyanobacterium Synechococcus sp. PCC 7002 . International Scientific Committee of the ISPP 16th International Symposium on Phototrophic Prokaryotes , Vancouver 2018-08-05 - 2018-08-09
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Academic lectureLale, Rahmi. (2018) Expanding the Synthetic Biology Toolbox. Prof. Bernhard Ø.Palsson Invited presentation, DTU Biosustainability , DTU, Copenhagen 2018-05-14 -
2017
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PosterVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2017) Streamlining recombination-mediated genetic engineering in Synechococcus sp. PCC 7002 by validating three neutral integration sites. SB 7.0 , Singapore 2017-06-13 - 2017-06-16
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Academic lectureLale, Rahmi; Valla, Svein; Balzer, Simone; Onsager, Ingerid; Lorentzen, Jon Andreas. (2017) DualUTR – A novel 5' UTR design for synthetic biology applications. UK Biochemical Society Synthetic Biology UK 2017 , Manchester 2017-11-27 - 2017-11-28
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Academic lectureLale, Rahmi. (2017) Communicating Science in the Digital Life Age. Senter for Digital Life Digital Life Conference , Oslo 2017-03-20 - 2017-03-21
2016
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PosterVogel, Anne Ilse Maria; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) A novel cost-efficient transformation protocol for Synechococcus sp. PCC 7002. Norwegian Plant Biology 2016, NTNU Gløshaugen Campus, Trondheim, Norway, June 15-17, 2016 2016-06-15 - 2016-06-17
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PosterVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Nanowire-mediated iron acquisition in Synechococcus sp. PCC7002. 12th Workshop on Cyanobacteria, Arizona State University, Tempe campus, May 19-22, 2016 2016-05-19 - 2016-05-22
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PosterLamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Pili-mediated metal acquisition – a physiological probe for protein-mediated electron transport? . Asilomar Bioelectronics Symposium, Asilomar Conference Grounds, Pacific Grove, CA, USA, September 5-8, 2016 2016-09-05 - 2016-09-08
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PosterVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Transformation efficiency for neutral integration sites in Synechococcus sp. PCC 7002. Umeå Renewable Energy Meeting (UREM 2016), Univesity of Umeå – KBC , 23-25 February 2016 2016-02-23 - 2016-02-25
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PosterVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Streamlining recombineering by validating three neutral integration sites in Synechococcus sp. PCC7002. 13th Nordic Photosynthesis Congress , Copenhagen 2016-10-25 - 2016-10-28
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LectureVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Nanowire-mediated iron acquisition in Synechococcus sp. PCC7002 . 13th Nordic Photosynthesis Congress , Copenhagen 2016-10-25 - 2016-10-28
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PosterVogel, Anne Ilse Maria; Lamb, Jacob Joseph; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) Streamlining recombineering by validating three neutral integration sites in Synechococcus sp. PCC7002 . 12th Workshop on Cyanobacteria , Phoenix 2016-05-19 - 2016-05-22
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PosterLamb, Jacob Joseph; Vogel, Anne Ilse Maria; Lale, Rahmi; Hohmann-Marriott, Martin Frank. (2016) The importance of pili-mediated metal acquisition in primary productivity. 2th Workshop on Cyanobacteria, Arizona State University, Tempe campus, May 19-22, 2016 2016-05-19 - 2016-05-22
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Academic lectureLale, Rahmi. (2016) Open Science Notebook. Ana Maria Delgado Aleman Open Tools and Infrastructures for Biology , Newcastle University 2016-01-20 - 2016-01-21
2015
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Interview
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PosterShojaei Moghadam, Morteza; Albersmeier, Andreas; Sharma, Animesh; Winkler, Anika; Cimmino, Lorenzo; Hohmann-Marriott, Martin Frank. (2015) Omics approaches for identification of gene candidate(s) encoding extracellular laccase like multicopper oxidase from Psychrobacter sp. P11F6 Isolated from marine arctic environment . Joint Genome Institute Microbial Genomics & Metagenomics Workshop 2015-09-14 - 2015-09-18
2014
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Academic lectureArnfinnsdottir, Nina Bjørk; Ottesen, Vegar; Lale, Rahmi; Sletmoen, Marit. (2014) Bacterial microarrays obtained by spontaneous adhesion of single bacteria on predefined spots on chemically patterned surfaces. Materials research society (MRS) 2014 MRS Fall Meeting & Exhibit , Boston 2014-11-30 - 2014-12-05
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Programme participationAlmaas, Eivind; Lale, Rahmi; Andersen, Maria; Moghaddam, Shiva; Stormo, Ellen; Adl, Patricia. (2014) Syntetisk biologi. Schrödingers Katt Schrödingers Katt [TV] 2014-03-27
2013
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PosterLale, Rahmi; Ünver, Deniz; Ertesvåg, Helga; Moghadam, Morteza Shojaei; Valla, Svein. (2013) Cold-adapted (psychrophilic) marine bacteria as expression hosts. MABIT Bioprosp_13 , Tromsø 2013-02-20 - 2013-02-22
2012
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PosterBalzer, Simone; Megerle, Judith; Tøndervik, Anne; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2012) The performance of the XylS/Pm expression cassette in relation to the most commonly used systems for bacterial recombinant expression. Cambridge Healthtech Institute Eighth Annual PEGS- 2012 , Boston, MA 2012-04-30 - 2012-05-04
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PosterRøkke, Gunvor; Lale, Rahmi; Stokke, Bjørn Torger; Sletmoen, Marit. (2012) Study of interaction forces between DNA and UNG using optical tweezers. Norwegian Physical Society Biophysics Meeting 2012 , Kongsvold fjellstue 2012-03-15 - 2012-03-17
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Academic lectureRøkke, Gunvor; Lale, Rahmi; Rowe, Alexander D.; Sletmoen, Marit. (2012) A study of G-quadruplex DNA using optical tweezers. Norwegian Research School in Medical Imaging The 4th PhD Conference in Medical Imaging , Trondheim 2012-11-28 - 2012-11-29
2011
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Academic lectureLale, Rahmi; Stuttgen, Friederike; Valla, Svein. (2011) xylS/Pm expression cassette optimisation for chromosomal expression. 6th Conference on Recombinant Protein Production , Vienna 2011-02-16 - 2011-02-19
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PosterJørgensen, Hanne; Lale, Rahmi; Valla, Svein. (2011) Use of the red fluorescent protein mCherry as a reporter gene in Pseudomonas putida to achieve higher levels of expression in the XylS/Pm regulator/promoter system. IV International Conference on Environmental, Industrial and Applied Microbiology-BioMicroWorld2011 , Torremolinos 2011-09-14 - 2011-09-16
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Academic lectureLale, Rahmi. (2011) In-silico design approaches for heterologous expression in bacteria. Bioinformatics for Young Scientists 2011 , Ullensvang, Hardanger 2011-03-16 - 2011-03-18
2010
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Academic lectureSkancke, Jørgen; Lale, Rahmi; Bar, Nadav. (2010) Free Energy Caculations Give Insight Into The Process of Promoter Escape. 11th International Conference on Systems Biology , Edinburgh, Scotland 2010-10-11 - 2010-10-14
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Academic lectureSekurova, Olga; Lale, Rahmi; Jørgensen, Hanne; Valla, Svein; Zotchev, Sergey. (2010) Development of new tools for heterologous expression of secondary metabolite gene clusters. 11th International Symposium on the Genetics of Industrial , Melbourne 2010-06-28 - 2010-07-01
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Academic lectureLale, Rahmi; Finnstun, Elin; Valla, Svein. (2010) Identification of Arctic Bacteria Useful for Expression of Cold-Active Enzymes. NBS Kontakmøtet 2010 , Storefjell 2010-01-14 - 2010-01-17
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Academic lectureLale, Rahmi. (2010) Abortive initiation. 1st NTNU Seminar on Nanobiotechnology and Nanomedicine , St. Olavs/Trondheim/NTNU 2010-02-19 - 2010-02-19
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PosterLale, Rahmi; Valla, Svein. (2010) Broad-host-range cloning/expression vectors. The 4th International Conference on Marine Biotechnology , Tromsø 2010-02-24 - 2010-02-25
2009
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Academic lectureLale, Rahmi; Stuttgen, Friederike; Bakke, Ingrid; Valla, Svein. (2009) A comprehensive combinatorial approach to achieve high-level heterologous protein expression by chromosomal integration of a single gene copy in Escherichia coli. NBS Kontakmøtet 2009 , Røros 2009-01-29 - 2009-02-01
2008
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Academic lectureLale, Rahmi; Berg, Laila; Bakke, Ingrid; Burroughs, N.; Valla, Svein. (2008) 5'-untranslated region’s role in transcription. 5th Congress on Recombinant Protein Production , Sardinia 2008-09-24 - 2008-09-28