Laila Marie Kristoffersen
+4797751601
Øya Helsehus, 7.etg
About
I am an Associate Professor in the Master's program in specialized nursing at ISM.
My primary research interests are pain and stress-reducing interventions for premature and sick newborns.
I am part of three research groups:
- Neonatal Medicine-NTNU Neo
- PEARL (Pain in Early Life)
- Pasientnær klinisk forskning
Field of study:
I defended my PhD project in March 2019, titled "Pain and stress in preterm infants - The impact of early skin-to-skin contact after birth on mother and child and the pain-relieving effect of skin-to-skin and different doses of sucrose," with Håkon Bergseng as the main supervisor and Ragnhild Støen as the co-supervisor. The project consisted of three (four) studies where the first examined the effect of skin-to-skin contact immediately after birth between mothers and moderately preterm infants. Studies two and three were randomized controlled trials (RCT) on pain relief during blood sampling and eye examinations. Study number four was a planned RCT on skin-to-skin contact immediately after birth for very preterm infants, with the protocol published. Several of the studies were multicenter studies with both national and international collaboration.
Until December 2023, I was a postdoctoral researcher on the project "A non-separation approach for very preterm infants in the delivery room: Does it matter for child outcomes and maternal mental health?"
In 2024, I started as the project leader for a multicenter study in Norway and Canada, the PROPER study. The study, initiated by St. Olavs Hospital and NTNU, aims to improve pain management and promote physiological stability in premature infants undergoing screening for retinopathy (ROP screening). The study also aims to better equip parents to actively participate in supporting their child during the eye examination. Despite more than 20 years of research on pain management during this examination, no effective method has yet been found.
Background
- 1991-2021: Nurse/Intensive Care Nurse at Neonatal Intensive Care, St. Olavs Hospital.
- 2001-2002: Specialization in Intensive Care Nursing, NTNU.
- 2003-2013: Research Assistant and Project Leader associated with various research and professional development projects at Neonatal Intensive Care, St. Olavs Hospital.
- 2009: Clinical Specialist in Intensive Care Nursing with a focus on pain.
- 2009-2011: Master in Health Sciences, NTNU.
- 2007-2013: Board Member of the Norwegian Perinatal Medicine Association (NPF).
- 2011-2015: Research Assistant in the project Computer-based Infant Movement Assessment (CIMA).
- 2011-2015: Board Member of the Norwegian Pediatric Pain Association (NBSF).
- 2013-2018: PhD Candidate in Clinical Medicine, IKOM, NTNU.
- 2019-: Associate Professor at ISM, NTNU.
- 2020-2023: Postdoctoral Researcher at IKOM, NTNU (50%) + Associate Professor at ISM, NTNU (50%).
- 2024-: Associate Professor at ISM (100%).
Competencies
Research
Publications
2025
-
McCord, Helen;
Rothfus, Melissa;
Disher, Tim;
Norris, Nadeana;
Jones, Karlee;
Kristoffersen, Laila Marie.
(2025)
Effectiveness and safety of intranasal fentanyl for pain management in infants aged 0–6 months: a systematic review protocol.
JBI Evidence Synthesis
Academic literature review
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Flottorp, Silje Tjøm;
Magerøy, Grete;
Hermansen Grunewaldt, Kristine.
(2025)
Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment: A Randomized Clinical Trial.
JAMA Network Open
Academic article
2024
-
Arribas, Cristina;
Cavallaro, Giacomo;
Gonzalez, Juan-Luis;
Lagares, Carolina;
Raffaeli, Genny;
Smits, Anne.
(2024)
Global cross-sectional survey on neonatal pharmacologic sedation and analgesia practices and pain assessment tools: impact of the sociodemographic index (SDI).
Pediatric Research
Academic article
2023
-
Kristoffersen, Laila Marie;
Bergseng, Håkon;
Engesland, Helene;
Bagstevold, Anne;
Aker, Karoline;
Støen, Ragnhild.
(2023)
Skin-to-skin contact in the delivery room for very preterm infants: a randomised clinical trial.
BMJ Paediatrics Open
Academic article
-
Føreland, Anne Marit;
Engesland, Helene;
Kristoffersen, Laila Marie;
Fegran, Liv.
(2023)
Tidlig hudkontakt er viktig også ved svært premature fødsler.
Tidsskriftet sykepleien
Article in business/trade/industry journal
2022
-
Føreland, Anne Marit;
Engesland, Helene;
Kristoffersen, Laila;
Fegran, Liv.
(2022)
Postpartum Experiences of Early Skin-to-Skin Contact and the Traditional Separation Approach After a Very Preterm Birth: A Qualitative Study Among Mothers.
Global Qualitative Nursing Research
Academic article
2019
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Follestad, Turid;
Theodorsson, Elvar;
Vederhus, Bente Johanne.
(2019)
Skin-to-skin contact during eye examination did not reduce pain compared to standard care with parental support in preterm infants.
Acta Paediatrica
Academic article
2018
-
Kristoffersen, Laila;
Malahleha, Moelo;
Duze, Zama;
Tegnander, Eva;
Kapongo, Ndaye;
Støen, Ragnhild.
(2018)
Randomised controlled trial showed that neonates received better pain relief from a higher dose of sucrose during venepuncture.
Acta Paediatrica
Academic article
-
Dahlø, Raija H. T.;
Gulla, Kari;
Saga, Susan;
Kristoffersen, Laila;
Eilertsen, Mary-Elizabeth B.
(2018)
Sacred hours: Mothers´ Experiences of Skin-to-skin Contact with Their Infants Immediately After Preterm Birth.
International Journal of Pediatrics & Neonatal Care
Academic article
2016
-
Kristoffersen, Laila;
Støen, Ragnhild;
Frances Hansen, Linda;
Wilhelmsen, Janne Elisabeth;
Bergseng, Håkon.
(2016)
Skin-to-Skin Care After Birth for Moderately Preterm Infants.
Journal of Obstetric, Gynecologic and Neonatal Nursing
Academic article
-
Kristoffersen, Laila;
Støen, Ragnhild;
Rygh, Hilde;
Sognnæs, Margunn;
Follestad, Turid;
Mohn, Hilde Stuedahl.
(2016)
Early skin-to-skin contact or incubatorfor very preterm infants: study protocol
for a randomized controlled trial.
Trials
Academic article
2015
-
Kristoffersen, Laila.
(2015)
Synliggjør forskjeller.
Sykepleien Forskning
Reader opinion piece
2011
-
Kristoffersen, Laila Marie;
Skogvoll, Eirik;
Hafstrøm, Maria Cecilia.
(2011)
Pain Reduction on Insertion of a Feeding Tube in Preterm Infants: A Randomized Controlled Trial.
Pediatrics
Academic article
2008
-
Hafström, Maria;
Kristoffersen, Laila;
Grunewaldt, Kristina Hermansen;
Rygg, Marite.
(2008)
Non-nutritive sucking in preterm infant with cerebral pathology.
Archives of Disease in Childhood
Abstract
Journal publications
-
McCord, Helen;
Rothfus, Melissa;
Disher, Tim;
Norris, Nadeana;
Jones, Karlee;
Kristoffersen, Laila Marie.
(2025)
Effectiveness and safety of intranasal fentanyl for pain management in infants aged 0–6 months: a systematic review protocol.
JBI Evidence Synthesis
Academic literature review
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Flottorp, Silje Tjøm;
Magerøy, Grete;
Hermansen Grunewaldt, Kristine.
(2025)
Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment: A Randomized Clinical Trial.
JAMA Network Open
Academic article
-
Arribas, Cristina;
Cavallaro, Giacomo;
Gonzalez, Juan-Luis;
Lagares, Carolina;
Raffaeli, Genny;
Smits, Anne.
(2024)
Global cross-sectional survey on neonatal pharmacologic sedation and analgesia practices and pain assessment tools: impact of the sociodemographic index (SDI).
Pediatric Research
Academic article
-
Kristoffersen, Laila Marie;
Bergseng, Håkon;
Engesland, Helene;
Bagstevold, Anne;
Aker, Karoline;
Støen, Ragnhild.
(2023)
Skin-to-skin contact in the delivery room for very preterm infants: a randomised clinical trial.
BMJ Paediatrics Open
Academic article
-
Føreland, Anne Marit;
Engesland, Helene;
Kristoffersen, Laila Marie;
Fegran, Liv.
(2023)
Tidlig hudkontakt er viktig også ved svært premature fødsler.
Tidsskriftet sykepleien
Article in business/trade/industry journal
-
Føreland, Anne Marit;
Engesland, Helene;
Kristoffersen, Laila;
Fegran, Liv.
(2022)
Postpartum Experiences of Early Skin-to-Skin Contact and the Traditional Separation Approach After a Very Preterm Birth: A Qualitative Study Among Mothers.
Global Qualitative Nursing Research
Academic article
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Follestad, Turid;
Theodorsson, Elvar;
Vederhus, Bente Johanne.
(2019)
Skin-to-skin contact during eye examination did not reduce pain compared to standard care with parental support in preterm infants.
Acta Paediatrica
Academic article
-
Kristoffersen, Laila;
Malahleha, Moelo;
Duze, Zama;
Tegnander, Eva;
Kapongo, Ndaye;
Støen, Ragnhild.
(2018)
Randomised controlled trial showed that neonates received better pain relief from a higher dose of sucrose during venepuncture.
Acta Paediatrica
Academic article
-
Dahlø, Raija H. T.;
Gulla, Kari;
Saga, Susan;
Kristoffersen, Laila;
Eilertsen, Mary-Elizabeth B.
(2018)
Sacred hours: Mothers´ Experiences of Skin-to-skin Contact with Their Infants Immediately After Preterm Birth.
International Journal of Pediatrics & Neonatal Care
Academic article
-
Kristoffersen, Laila;
Støen, Ragnhild;
Frances Hansen, Linda;
Wilhelmsen, Janne Elisabeth;
Bergseng, Håkon.
(2016)
Skin-to-Skin Care After Birth for Moderately Preterm Infants.
Journal of Obstetric, Gynecologic and Neonatal Nursing
Academic article
-
Kristoffersen, Laila;
Støen, Ragnhild;
Rygh, Hilde;
Sognnæs, Margunn;
Follestad, Turid;
Mohn, Hilde Stuedahl.
(2016)
Early skin-to-skin contact or incubatorfor very preterm infants: study protocol
for a randomized controlled trial.
Trials
Academic article
-
Kristoffersen, Laila.
(2015)
Synliggjør forskjeller.
Sykepleien Forskning
Reader opinion piece
-
Kristoffersen, Laila Marie;
Skogvoll, Eirik;
Hafstrøm, Maria Cecilia.
(2011)
Pain Reduction on Insertion of a Feeding Tube in Preterm Infants: A Randomized Controlled Trial.
Pediatrics
Academic article
-
Hafström, Maria;
Kristoffersen, Laila;
Grunewaldt, Kristina Hermansen;
Rygg, Marite.
(2008)
Non-nutritive sucking in preterm infant with cerebral pathology.
Archives of Disease in Childhood
Abstract
Teaching
Courses
- SYT3100 - Project Plan
- SYT3530 - Intensive care nursing 1
- SYT3531 - Intensive care nursing 2
- SYT3537 - Competent Practitioner of Intensiv care nursing
- SYT3500 - Project plan, theory of science and research ethics
- SYT3535 - Basic Critical Care Nursing, Clinical studies
- SYT3536 - Shared Responsibility of Critical Care Nursing
- SYT3107 - Project Plan
Supervision
Main supervisor and co-supervisor for master's students in specialized nursing at NTNU.
Main supervisor for a PhD candidate associated with The PROPER study.
Outreach
2022
-
Academic lectureKristoffersen, Laila Marie. (2022) Immediate KMC -Experience in Norway. Steering Committee of International Network of KMC XIII International Conference on Kangaroo Mother Care , Madrid, November 2022 2022-11-21 - 2022-11-24
2017
-
PosterKristoffersen, Laila; Malahleha, Moelo; Duze, Zama; Tegnander, Eva; Kapongo, Ndaye; Støen, Ragnhild. (2017) Sucrose as pain relief in preterm and full term infants: A randomized controlled study of two different doses. Priorities in Perinatal Care Association 36th conference on priorities in perinatal care in Southern Africa , Mpekweni, South Africa 2017-03-07 - 2017-03-10
-
PosterKristoffersen, Laila; Malahleha, Moelo; Duze, Zama; Tegnander, Eva; Kapongo, Ndaye; Støen, Ragnhild. (2017) Hvor mye sukker er nok som smertelindring? En samarbeidsstudie mellom Norge og Sør-Afrika. Norsk Perinatalmedisinsk Forening De 30. norske Perinataldager , Ålesund 2017-11-15 - 2017-11-17
2015
-
InterviewKristoffersen, Laila. (2015) Dataprogram ser smerte hos nyfødte. forskning.no forskning.no [Internet] 2015-02-04
-
Academic lectureKristoffersen, Laila; Støen, Ragnhild; Bergseng, Håkon. (2015) SKIN-TO-SKIN IN DELIVERY ROOM FOR PRETERM INFANTS 28-31 WEEKS. Helse Midt-Norge RHF Regional forskningskonferanse , Stjørdal 2015-06-09 - 2015-06-10
-
PosterKristoffersen, Laila; Støen, Ragnhild; Hansen, Linda; Williamsen, Janne; Bergseng, Håkon. (2015) Skin-to-skin contact versus incubator in delivery room for preterm infants with gestational age 32-34 weeks . Pediatric Academic Societies PAS , San Diego 2015-04-25 - 2015-05-28
-
Academic lectureKristoffersen, Laila; Støen, Ragnhild; Bergseng, Håkon. (2015) Hud-mot-hud eller standardbehandling rett etter fødsel? . Norsk Perinatalmedisinsk forening Perinataldagene , Bergen 2015-11-04 - 2015-11-06
2014
-
PosterKristoffersen, Laila Marie; Støen, Ragnhild; Bergseng, Håkon; Dahlø, Raija Helena Tolonen; Gulla, Kari. (2014) Skin-to-skin versus incubator for preterm infants. International Confederation of Midwives ICM 30th Triennal Congress , Praha 2014-06-01 - 2014-06-05
-
InterviewKristoffersen, Laila. (2014) Forsker på hud-mot-hud-kontakt for for tidlig fødte barn . moss avis moss avis [Newspaper] 2014-08-09
2013
-
PosterFjørtoft, Toril Synnøve Larsso; Støen, Ragnhild; Vågen, Randi; Øberg, Gunn Kristin; Labori, Cathrine; Songstad, Nils Thomas. (2013) Abnormal motor repertoire is common in extremely preterm born infants presenting normal fidgety movements. Pediatric Academic Societies 2013-05-04 - 2013-05-07
2008
-
PosterKristoffersen, Laila; Skogvoll, Eirik; Hafström, Maria. (2008) Reducing pain from feeding tube insertion in preterm infants. European Academy of Paediatrics, The 2nd Congress of the European Academy of Paediatrics 2008-10-24 - 2008-10-28
2007
-
PosterHafström, Maria; Kristoffersen, Laila; Grunewaldt, Kristine Hermansen; Rygg, Marite. (2007) Non-nutritive sucking in the high-risk preterm infant. The European Pediatric Neurology Society 7th European Congress of the European Pediatric Neurology Society and the 9th Congress of the Turkish Child Neurology Society , Kusadasi 2007-09-26 - 2007-09-29