Hans Einar Krokan
Publications
2023
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Lefol, Yohan Pierre;
Korfage, Tom;
Mjelle, Robin;
Prebensen, Christian Haugland;
Lüders, Torben;
Müller, Bruno.
(2023)
TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data.
NAR Genomics and Bioinformatics
Academic article
2022
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Bonagas, Nadilly;
Gustafsson, Nina M. S.;
Henriksson, Martin;
Marttila, Petra;
Gustafsson, Robert;
Wiita, Elisée.
(2022)
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Nature Cancer
Academic article
2021
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Olinski, Ryszard;
Slupphaug, Geir;
Foksinski, Marek;
Krokan, Hans Einar.
(2021)
Genomic Uracil and Aberrant Profile of Demethylation Intermediates in Epigenetics and Hematologic Malignancies.
International Journal of Molecular Sciences
Academic article
2020
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Visnes, Torkild;
Benitez-Buelga, Carlos;
Cázares-Körner, Armando;
Sanjiv, Kumar;
Hanna, Bishoy M F;
Mortusewicz, Oliver.
(2020)
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Research (NAR)
Academic article
-
Boeckemeier, L;
Kraehenbuehl, R;
Keszthelyi, A;
Gasasira, MU;
Vernon, EG;
Beardmore, R.
(2020)
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Science Advances
Academic article
-
Kavli, Bodil Merete;
Slupphaug, Geir;
Krokan, Hans Einar.
(2020)
Genomic Uracil in Biology, Immunity and Cancer.
Royal Society of Chemistry (RSC) Publishing
Academic chapter/article/Conference paper
2019
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Sarno, Antonio;
Lundbæk, Marie Benner;
Liabakk, Nina-Beate;
Aas, Per Arne;
Mjelle, Robin;
Hagen, Lars.
(2019)
Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.
Nucleic Acids Research (NAR)
Academic article
2018
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Slupphaug, Geir;
Krokan, Hans Einar.
(2018)
Genomic Uracil – Valuable Tool in Molecular Biology but Inherent Problem in Sequencing of Ancient DNA.
World Scientific
Chapter
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Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Viral Uracil - Uracil DNA glycosylases and dUTPases.
World Scientific
Chapter
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Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2018)
Routes to Uracil in DNA.
World Scientific
Chapter
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Slupphaug, Geir;
Krokan, Hans Einar.
(2018)
Genomic Uracil - Evolution, Biology, Immunology and Disease.
World Scientific
World Scientific
Non-fiction book
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Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
DNA Repair is Integrated with Many Cellular Processes.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Sarno, Antonio;
Slupphaug, Geir.
(2018)
Enzymology of Genomic Uracil Repair.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir;
Drabløs, Finn.
(2018)
The Earth, Life and Genomic Uracil.
World Scientific
Chapter
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Visnes, Torkild;
Armando, Cazares-Körner;
Wenjing, Hao;
Wallner, Olov;
Masuyer, Geoffrey;
Loseva, Olga.
(2018)
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science
Academic article
2017
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Wang, Yufei;
McKay, James D.;
Rafnar, Thorunn;
Wang, Zhaoming;
Timofeeva, Maria N.;
Broderick, Peter.
(2017)
Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (Nature Genetics (2014) 46 (736-741)).
Nature Genetics
Errata
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Krokan, Hans Einar;
Slupphaug, Geir;
Kavli, Bodil Merete.
(2017)
Genomic Uracil-Dangers and Benefits in processing.
Academic chapter/article/Conference paper
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Alsøe, Lene;
Sarno, Antonio;
Carracedo Huroz, Sergio;
Domanska, Diana Ewa;
Dingler, Felix;
Lirussi, Lisa.
(2017)
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Scientific Reports
Academic article
2016
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Rasmussen, Erik;
Vågbø, Cathrine Broberg;
Münch, Daniel;
Krokan, Hans Einar;
Klungland, Arne;
Amdam, Gro Vang.
(2016)
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates.
Biochemistry and Biophysics Reports
Academic article
-
Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Academic article
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Xue, JH;
Xu, GF;
Gu, TP;
Chen, GD;
Han, BB;
Xu, ZM.
(2016)
Uracil-DNA glycosylase UNG promotes tet-mediated DNA demethylation.
Journal of Biological Chemistry
Academic article
-
Helander, Linda;
Sharma, Animesh;
Krokan, Hans Einar;
Plaetzer, Kristjan;
Krammer, Barbara;
Tortik, Nicole.
(2016)
Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins.
Molecular Biosystems
Academic article
2015
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Helander, Linda;
Krokan, Hans Einar;
Gederaas, Odrun Arna;
Johnsson, Anders Carl G.;
Chen, Duan.
(2015)
Hexylaminolevulinate Photodynamic Treatment of Cancer Cell Lines. PhD Thesis.
Tapir Akademisk Forlag
Tapir Akademisk Forlag
Doctoral dissertation
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Academic article
-
Brenner, Darren. R.;
Amos, Christopher I.;
Brhane, Yonathan;
Timofeeva, Maria N.;
Caporaso, Neil;
Wang, Yufei.
(2015)
Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.
Carcinogenesis
Academic article
-
Mjelle, Robin;
Hegre, Siv Anita;
Aas, Per Arne;
Slupphaug, Geir;
Drabløs, Finn;
Sætrom, Pål.
(2015)
Cell cycle regulation of human DNA repair and chromatin remodeling genes.
DNA Repair
Academic article
2014
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Wang, Yufei;
McKay, JD;
Rafnar, T;
Wang, Z;
Timofeeva, MN;
Broderick, P.
(2014)
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
Nature Genetics
Academic article
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Academic article
-
Hu, Yi;
Ericsson, Ida;
Doseth, Berit;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2014)
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors.
Experimental Cell Research
Academic article
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Wallenius, Anders;
Hauser, Jannek;
Aas, Per Arne;
Sarno, Antonio;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2014)
Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification.
Molecular Immunology
Academic article
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Zdzalik, Daria;
Vågbø, Cathrine Broberg;
Kirpekar, F;
Davydova, Erna;
Puścian, Alicja;
Maciejewska, Agnieszka M..
(2014)
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities.
PLOS ONE
Academic article
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Helander, Linda;
Krokan, Hans Einar;
Johnsson, Anders Carl G.;
Gederaas, Odrun Arna;
Plaetzer, Kristjan.
(2014)
Red versus blue light illumination in hexyl 5-aminolevulinate photodynamic therapy: the influence of light color and irradiance on the treatment outcome in vitro.
Journal of Biomedical Optics
Academic article
2013
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Bjørngaard, Johan Håkon;
Gunnell, David;
Gabrielsen, Maiken Elvestad;
Davey Smith, George;
Skorpen, Frank;
Krokan, Hans Einar.
(2013)
The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study.
Psychological Medicine
Academic article
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Overland, Hilde Bremseth;
Schønberg, Svanhild Margrethe Arentz;
Krokan, Hans Einar.
(2013)
ER stress, reactive oxygen species and autophagy in colon cancer cells treated with polyunsaturated marine fatty acids.
Doktoravhandlinger ved NTNU (1)
Doctoral dissertation
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Ericsson, Ida;
Galashevskaya, Anastasia;
Sarno, Antonio;
Aas, Per Arne.
(2013)
Genomic uracil - potent mutagen but normal intermediate in adaptive immunity.
The FEBS Journal
Abstract
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Hu, Yi;
Ericsson, Ida;
Torseth, Kathrin;
Methot, Stephen;
Sundheim, Ottar;
Liabakk, Nina-Beate.
(2013)
A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
Journal of Molecular Biology (JMB)
Academic article
-
Zheng, Guanqun;
Dahl, John Arne;
Niu, Yamei;
Fedorcsak, Peter;
Huang, Chun-Min;
Li, Charles J..
(2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.
Molecular Cell
Academic article
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Vågbø, Cathrine Broberg;
Svaasand, Eva Kathrine;
Aas, Per Arne;
Krokan, Hans Einar.
(2013)
Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Bjørås, Magnar.
(2013)
Base Excision Repair.
Cold Spring Harbor Perspectives in Biology
Academic article
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Galashevskaya, Anastasia;
Sarno, Antonio;
Vågbø, Cathrine Broberg;
Aas, Per Arne;
Hagen, Lars;
Slupphaug, Geir.
(2013)
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.
DNA Repair
Academic article
-
Hegre, Siv Anita;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Otterlei, Marit;
Krokan, Hans Einar.
(2013)
Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase.
DNA Repair
Academic article
-
Diaz, Javier Pena;
Hegre, Siv Anita;
Anderssen, Endre;
Aas, Per Arne;
Mjelle, Robin;
Gilfillan, Gregor Duncan.
(2013)
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.
Nucleic Acids Research (NAR)
Academic article
-
Gabrielsen, Maiken Elvestad;
Romundstad, Pål Richard;
Langhammer, Arnulf;
Krokan, Hans Einar;
Skorpen, Frank.
(2013)
Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56 307 individuals from the HUNT study in Norway.
European Journal of Human Genetics
Academic article
2012
-
Krokan, Hans Einar.
(2012)
A life in DNA repair-And beyond.
DNA Repair
Editorial
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Torseth, Kathrin;
Doseth, Berit;
Hagen, Lars;
Olaisen, Camilla;
Liabakk, Nina-Beate;
Græsmann, Heidi.
(2012)
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.
DNA Repair
Academic article
-
Doseth, Berit;
Ekre, Cecilie;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2012)
Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
DNA Repair
Academic article
-
Krokan, Hans Einar.
(2012)
To Repair and Protect.
International Innovation
Popular scientific article
-
Krokan, Hans Einar.
(2012)
Stable Genomes and DNA Repair.
International Innovation
Popular scientific article
-
Krokan, Hans Einar.
(2012)
The Essentials of DNA Repair.
Public Service Review: European Union
Popular scientific article
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Timofeeva, MN;
Hung, RJ;
Rafnar, T;
Christiani, DC;
Field, JK;
Bickeboller, H.
(2012)
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
Human Molecular Genetics
Academic article
-
Meza, Trine Johansen;
Moen, Marivi;
Vågbø, Cathrine Broberg;
Krokan, Hans Einar;
Klungland, Arne;
Grini, Paul Eivind.
(2012)
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.
Nucleic Acids Research (NAR)
Academic article
-
Akbari, Mansour;
Krokan, Hans Einar.
(2012)
Base excision repair efficiency and mechanism in nuclear extracts are influenced by the ratio between volume of nuclear extraction buffer and nuclei-Implications for comparative studies.
Mutation research
Academic article
-
Kazma, R;
Babron, MC;
Gaborieau, Valerie;
Génin, E;
Brennan, P;
Hung, Rayjean J..
(2012)
Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium.
Carcinogenesis
Academic article
-
Johnson, Matthew P;
Brennecke, Shaun P.;
Iversen, Ann-Charlotte;
East, Christine;
Olsen, Guro Dalheim;
Kent, Jack W.
(2012)
Genome-wide association scans identify novel maternal susceptibility loci for preeclampsia.
Pregnancy Hypertension
Abstract
2011
-
Robertson, Adam Brian;
Dahl, John Arne;
Vågbø, Cathrine Broberg;
Tripathi, P;
Krokan, Hans Einar;
Klungland, Arne.
(2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Research (NAR)
Academic article
-
Arum, Carl-Jørgen;
Gederaas, Odrun Arna;
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Hjelde, Astrid;
Krokan, Hans Einar.
(2011)
Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action.
Journal of Biomedical Optics
Academic article
-
Leihne, VIbeke;
Kirpekar, F;
Vågbø, Cathrine Broberg;
Van den Born, Erwin;
Krokan, Hans Einar;
Grini, Paul Eivind.
(2011)
Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.
Nucleic Acids Research (NAR)
Academic article
-
Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR)
Academic article
-
Hanssen-Bauer, Audun;
Solvang-Garten, Karin;
Sundheim, Ottar;
Diaz, Javier Pena;
Andersen, Sonja Benedikte;
Slupphaug, Geir.
(2011)
XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage.
Environmental and Molecular Mutagenesis
Academic article
-
Sletta, Håvard;
Klinkenberg, Geir;
Winnberg, Asgeir;
Kvitvang, Hans Fredrik Nyvold;
Nilsen, Marianne Bakke;
Krokan, Hans Einar.
(2011)
A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants.
Journal of Microbiological Methods
Academic article
-
Doseth, Berit;
Visnes, Torkild;
Wallenius, Anders;
Ericsson, Ida;
Sarno, Antonio;
Pettersen, Henrik Sahlin.
(2011)
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE.
Journal of Biological Chemistry
Academic article
-
Van den Born, Erwin;
Vågbø, Cathrine Broberg;
Songe-Møller, Lene;
Leihne, VIbeke;
Lien, Guro Flor;
Leszczynska, G.
(2011)
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.
Nature Communications
Academic article
-
Baglo, Yan;
Sousa, Mirta;
Slupphaug, Geir;
Hagen, Lars;
Håvåg, Sissel;
Helander, Linda.
(2011)
Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways.
Photochemical and Photobiological Sciences
Academic article
2010
-
Monsen, Vivi A Talstad;
Sundheim, Ottar;
Aas, Per Arne;
Westbye, Marianne Pedersen;
Sousa, Mirta;
Slupphaug, Geir.
(2010)
Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar.
(2010)
Advarer mot biodiesel i fossilt diesel: Svært mange kan bli syke.
Teknisk Ukeblad
Interview Journal
-
Monsen, Vivi A Talstad;
Krokan, Hans Einar;
Aas, Per Arne.
(2010)
Mechanisms of alkylation damage repair by human AlkB homologues.
NTNU
Doctoral dissertation
-
Songe-Møller, Lene;
Van den Born, Erwin;
Leihne, V;
Vågbø, Cathrine Broberg;
Kristoffersen, T;
Krokan, Hans Einar.
(2010)
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding.
Molecular and Cellular Biology
Academic article
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Størvold, Gro Leite;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2010)
DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells.
Nutrition and Cancer
Academic article
-
Akbari, Mansour;
Solvang-Garten, Karin;
Hanssen-Bauer, Audun;
Lieske, Nora V.;
Pettersen, Henrik P Sahlin;
Pettersen, Grete Klippenvåg.
(2010)
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Otterlei, Marit;
Akbari, M.;
Slupphaug, Geir;
Aas, Per Arne.
(2010)
DNA repair and cancer.
European Journal of Cancer
Abstract
2009
-
Visnes, Torkild;
Doseth, Berit;
Pettersen, Henrik Sahlin;
Hagen, Lars;
Sousa, Mirta;
Akbari, Mansour.
(2009)
Uracil in DNA and its processing by different DNA glycosylases.
Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic literature review
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2009)
The Antiproliferative Effect of EPA in HL60 Cells is Mediated by Alterations in Calcium Homeostasis.
Lipids
Academic article
-
Størvold, Gro Leite;
Fleten, Karianne Giller;
Olsen, Cathrine Goberg;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2009)
Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells.
Lipids
Academic article
-
Gilljam, Karin Margaretha;
Feyzi, Emadoldin;
Aas, Per Arne;
Sousa, Mirta;
Müller, Rebekka;
Vågbø, Cathrine Broberg.
(2009)
Identification of a novel, widespread, and functionally important PCNA-binding motif.
Journal of Cell Biology
Academic article
-
Akbari, Mansour;
Diaz, Javier Pena;
Andersen, Sonja Benedikte;
Liabakk, Nina-Beate;
Otterlei, Marit;
Krokan, Hans Einar.
(2009)
Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity.
DNA Repair
Academic article
-
Aas, Per Arne;
Diaz, Javier Pena;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Skorpen, Frank.
(2009)
Overexpression of transcription factor AP-2 stimulates the P-A promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Visnes, Torkild.
(2009)
DNA Excision repair of uracil and 5-fluorouracil in human cancer cell lines.
Det medisinske fakultet, NTNU
Doctoral dissertation
-
Landi, MT;
Chatterjee, N;
Yu, K;
Goldin, LR;
Goldstein, AM;
Rotunno, M.
(2009)
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.
American Journal of Human Genetics
Academic article
2008
-
Hung, RJ;
Mckay, J;
Gaborieau, V;
Boffetta, P;
Chu, C;
Field, JK.
(2008)
Detecting new genes for tobacco-related cancers - genomewide association study of lung cancer.
European Journal of Cancer
Abstract
-
Akbari, Mansour;
Krokan, Hans Einar.
(2008)
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging.
Mechanisms of Ageing and Development
Academic literature review
-
Andersen, Sonja Benedikte;
Krokan, Hans Einar;
Baar, Cecilie Christensen;
Rakvag, Trude Teoline;
Laugsand, Eivor Alette;
Kvam, Tor-Morten.
(2008)
Identification of an alternative, putative promoter and new alternatively spliced transcripts from the human µ opioid receptor gene, OPRM1.
Palliative Medicine
Abstract
-
Heath, SC;
Gut, IG;
Brennan, P;
Mckay, JD;
Bencko, V;
Fabianova, E.
(2008)
Investigation of the fine structure of European populations with applications to disease association studies.
European Journal of Human Genetics
Academic article
-
McKay, JD;
Mckay, JD;
Hung, RJ;
Gaborieau, V;
Boffetta, Paolo;
Chabrier, Amelie.
(2008)
Lung cancer susceptibility locus at 5p15.33.
Nature Genetics
Academic article
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2008)
The antiproliferative effect of EPA in HL60 cells is mediated by alterations in calcium homeostasis.
Lipids
Academic article
-
Hung, RJ;
Mckay, JD;
Gaborieau, V;
Boffetta, P;
Hashibe, M;
Zaridze, D.
(2008)
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
Nature
Academic article
-
Bathen, Tone Frost;
Holmgren, Kristin;
Lundemo, Anne Gøril;
Hjelstuen, Mari H;
Krokan, Hans Einar;
Gribbestad, Ingrid S.
(2008)
Omega-3 Fatty Acids Supress Growth of SW620 Human Colon Cancer Xenografts in Nude Mice.
Anticancer Research
Academic article
-
Akbari, Mansour;
Visnes, Torkild;
Krokan, Hans Einar;
Otterlei, Marit.
(2008)
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis.
DNA Repair
Academic article
-
Sundheim, Ottar;
Talstad, Vivi A;
Vågbø, Cathrine Broberg;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
AlkB demethylases flip out in different ways.
DNA Repair
Academic article
-
Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry
Academic article
-
Visnes, Torkild;
Akbari, Mansour;
Hagen, Lars;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
The rate of base excision repair of uracil is controlled by the initiating glycosylase.
DNA Repair
Academic article
-
Krokan, Hans Einar.
(2008)
NBS 40 år.
NBS-nytt
Popular scientific article
-
Hagen, Lars;
Kavli, Bodil Merete;
Sousa, Mirta;
Torseth, Kathrin;
Liabakk, Nina-Beate;
Sundheim, Ottar.
(2008)
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
EMBO Journal
Academic article
-
Jakobsen, CH;
Pettersen, Caroline Hild;
Størvold, Gro Leite;
Bremseth, Hilde;
Follestad, Turid;
Sand, Kristin.
(2008)
DHA induces ER stress and growth arrest in human colon cancer cells: association with cholesterol and calcium homeostasis.
Journal of Lipid Research
Academic article
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Arum, Carl-Jørgen;
Hjelde, Astrid;
Zhao, Chun-Mei.
(2008)
Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy.
Journal of Biomedical Optics
Academic article
2007
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
Repair of small base lesions in DNA - From molecular biology to phenotype - Preface.
DNA Repair
Editorial
-
Sousa, Mirta;
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
DNA-uracil and human pathology.
Molecular Aspects of Medicine
Academic literature review
-
Feyzi, Emadoldin;
Aas, Per Arne;
Sundheim, Ottar;
Westbye, Marianne;
Vågbø, Cathrine Broberg;
Otterlei, Marit.
(2007)
RNA Base Damage and Repair.
Current Pharmaceutical Biotechnology
Academic literature review
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
Repair of small base lesions in DNA- from molecular biology to phenotype.
DNA Repair
Abstract
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Akbari, Mansour;
Visnes, Torkild;
Pettersen, Henrik P Sahlin;
Sundheim, Ottar.
(2007)
Repair og uracil in DNA by UNG2 and SMUG1 - an update.
DNA Repair
Abstract
-
Pettersen, Henrik P Sahlin;
Sundheim, Ottar;
Gilljam, Karin Margaretha;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2007)
Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.
Nucleic Acids Research (NAR)
Academic article
-
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
Uracil in DNA - General mutagen, but normal intermediate in acquired immunity.
DNA Repair
Academic article
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Krokan, Hans Einar;
Hjelme, Dag Roar;
Svaasand, Lars O..
(2007)
In vitro study on methemoglobin formation in erythrocytes following hexyl-aminolevulinate induced photodynamic therapy.
SPIE - The International Society for Optics and Photonics
Academic chapter/article/Conference paper
-
Akbari, Mansour;
Otterlei, Marit;
Pena-Diaz, J;
Krokan, Hans Einar.
(2007)
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress.
Neuroscience
Academic article
2006
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Arum, Carl-Jørgen;
Krokan, Hans Einar;
Chen, Duan.
(2006)
Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy.
Lasers in Surgery and Medicine
Abstract
-
Hagen, Lars;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2006)
Genomic uracil and human disease.
Experimental Cell Research
Academic literature review
-
Krokan, Hans Einar;
Akbari, Mansour;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Ericsson, Madelene.
(2006)
Base excision repair proteins in cancer prevention and acquired immune responses.
The FEBS Journal
Abstract
-
Ringvoll, Jeanette;
Ringvoll, Jeanette;
Nordstrand, Line M.;
Vågbø, Cathrine Broberg;
Vagbo, CB;
Talstad, Vivi.
(2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
EMBO Journal
Academic article
-
Sundheim, Ottar;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Mittelstedt, L.Mirta;
Talstad, Vivi;
Aas, Per Arne.
(2006)
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
EMBO Journal
Academic article
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Krokan, Hans Einar.
(2006)
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress.
Neuroscience
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2006)
Preface.
DNA Repair
Academic article
-
Schønberg, Svanhild Margrethe Arentz;
Lundemo, Anne Gøril;
Fladvad, Torill;
Holmgren, Kristin;
Bremseth, Hilde;
Nilsen, Asbjørn Magne.
(2006)
Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory element-binding protein 1.
The FEBS Journal
Academic article
2005
-
Hjelde, Astrid;
Gederaas, Odrun Arna;
Krokan, Hans Einar;
Brubakk, Alf O.
(2005)
Lack of effect of hyperoxia on photodynamic therapy and lipid peroxidation in three different cancer cell lines.
Medical Science Monitor
Academic article
-
Kavli, Bodil Merete;
Andersen, Sonja Benedikte;
Otterlei, Marit;
Liabakk, Nina-Beate;
Imai, K;
Fischer, A.
(2005)
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
Journal of Experimental Medicine (JEM)
Academic article
-
Gederaas, Odrun Arna;
Schønberg, Svanhild Margrethe Arentz;
Ramstad, Ståle;
Berg, Kristian;
Johnsson, Anders Carl G.;
Krokan, Hans Einar.
(2005)
Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization.
Photochemical and Photobiological Sciences
Academic article
-
Andersen, Sonja Benedikte;
Heine, T;
Sneve, Ragnhild;
Kønig, Imbritt;
Krokan, Hans Einar;
Epe, B.
(2005)
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.
Carcinogenesis
Academic article
-
Andersen, Sonja Benedikte;
Ericsson, Maria Elisabeth Madelene;
Dai, HY;
Diaz, Javier Pena;
Slupphaug, Geir;
Nilsen, H.
(2005)
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
DNA Repair
Academic article
-
Auerbach, Paul;
Bennett, Richard A.O.;
Bailey, Elisabeth A.;
Krokan, Hans Einar;
Demple, Bruce.
(2005)
Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Schønberg, Svanhild Margrethe Arentz;
Jakobsen, Caroline Hild;
Bremseth, Hilde;
Olsen, Karina Standahl;
Lundemo, Anne Gøril;
Follestad, Turid.
(2005)
Endoplasmic reticulum stress induced by DHA leads to growth arrest of human colon cancer cells.
Chemistry and Physics of Lipids
Academic article
-
Akbari, Mansour;
Hansen, Marianne Dore;
Halgunset, Jostein;
Skorpen, Frank;
Krokan, Hans Einar.
(2005)
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.
Journal of Molecular Diagnostics
Academic article
-
Rakvag, Trude Teoline;
Klepstad, Pål;
Baar, Cecilie Christensen;
Kvam, Tor-Morten;
Dale, Ola;
Kaasa, Stein.
(2005)
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Pain
Academic article
-
Andersen, S;
Heine, T;
Sneve, Ragnhild;
Konig, I;
Krokan, HE;
Epe, B.
(2005)
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.
Carcinogenesis
Academic article
-
Andersen, S;
Ericsson, M;
DAI, H;
Peña-Diaz, J;
Slupphaug, G;
Nilsen, Hilde.
(2005)
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
DNA Repair
Academic article
2004
-
Krokan, Hans Einar.
(2004)
Molecular and functional interactions in macromolecular repair.
European Journal of Biochemistry (EJB)
Abstract
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2004)
Novel aspects of macromolecular repair and relationship to human disease.
Journal of Molecular Medicine
Academic literature review
-
Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair
Academic literature review
-
Kvam, TM;
Baar, Cecilie Christensen;
Raakvag, Trude Teoline;
Kaasa, Stein;
Krokan, Hans Einar;
Skorpen, Frank.
(2004)
Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing.
Journal of Molecular Medicine
Academic article
-
Klepstad, Pål;
Rakvag, TT;
Kaasa, Stein;
Holthe, Monica;
Dale, Ola;
Borchgrevink, Petter Chr..
(2004)
The 118 A>G polymorphism in the human mu-opioid receptor gene may increase morphins requirements in patients with pain caused by malignant disease.
Acta Anaesthesiologica Scandinavica
Academic article
-
Akbari, Mansour;
Skjelbred, C;
Folling, I;
Sagen, J;
Krokan, Hans Einar.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
-
Diaz, Javier Pena;
Akbari, Mansour;
Sundheim, Ottar;
Farez-Vidal, ME;
Andersen, S;
Sneve, R.
(2004)
Trypanosoma cruzi contains a single detectable uracil-DNA glycosylase and repairs uracil exclusively via short patch base excision repair.
Journal of Molecular Biology (JMB)
Academic article
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Aas, Per Arne;
Kavli, Bodil;
Liabakk, Nina-Beate.
(2004)
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.
Nucleic Acids Research (NAR)
Academic article
-
Akbari, M;
Skjelbred, C;
Folling, I;
Sagen, Jørn V.;
Krokan, HE.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA (Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
-
Klepstad, Pål;
Rakvag, Trude Teoline;
Kaasa, Stein;
Holthe, Monica;
Dale, Ola;
Borchgrevink, Petter Chr..
(2004)
The 118 A>G polymorphism in the human µ-opioidreceptor gene may increase morphine requrements in patients with pain caused by malignant disease.
Acta Anaesthesiologica Scandinavica
Academic article
-
Akbari, M;
Skjelbred, C;
Følling, Ivar;
Sagen, J;
Krokan, H E.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA Leu (UUR)) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
2003
-
Holthe, M.;
Rakvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2003)
Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.
The Pharmacogenomics Journal
Academic article
-
Slupphaug, Geir;
Kavli, Bodil;
Krokan, Hans Einar.
(2003)
Interacting pathways that prevent and repair oxidative DNA damage.
Mutation Research (DNA Repair)
Academic article
-
Nilsen, Hilde;
Stamp, G;
Andersen, Sonja;
Hrivnak, G;
Krokan, Hans Einar;
Lindahl, T.
(2003)
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.
Oncogene
Academic article
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature
Academic article
-
Imai, K;
Slupphaug, Geir;
Lee, W-I;
Revy, P;
Nonoyama, S;
Catalan, N.
(2003)
Uracil-DNA glycosylase deficiency profoundly impairs immunoglobulin class switch.
Nature Immunology
Academic article
-
Holthe, Monica;
Råkvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2003)
Identification of 10 novel single nucleotide polymorphisms and analysis of their relevance to morphine glucuronidation.
The Pharmacogenomics Journal
Academic article
2002
-
Holthe, Monica;
Klepstad, Pål;
Zahlsen, Kolbjørn;
Borchgrevink, Petter Chr.;
Hagen, Lars;
Dale, Ola.
(2002)
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1a1*28 polymorphisms in cancer patients on chronic morphine therapy.
European Journal of Clinical Pharmacology
Academic article
-
Krokan, Hans Einar;
Drabløs, Finn;
Slupphaug, Geir.
(2002)
Uracil in DNA, occurrence, consequences and repair.
Oncogene
Academic article
-
Kavli, Bodil;
Sundheim, Ottar;
Akbari, Mansour;
Otterlei, Marit;
Nilsen, Hilde;
Skorpen, Frank.
(2002)
hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup.
Journal of Biological Chemistry
Academic article
-
Krokan, Hans Einar.
(2002)
Fromprotein folding to new enzymes.
Tidsskrift for Den norske legeforening
Academic article
-
Holthe, Monica;
Råkvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2002)
Sequence variationin the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphins (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.
The Pharmacogenomics Journal
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2002)
Damage and repair of DNA in mammalian cells-emphasis on oxidative damage. Proceedings from International Symposium "Natural Ionising Radiation and Health".
Det Norske Videnskaps-Akademi : proceedings
Academic article
-
Grøsvik, K;
Slupphaug, Geir;
Krokan, Hans Einar.
(2002)
"Characterisation of uracil-exising enzyme activities in organ extracts from UNG knockout and wild-type mice.".
NTNU
Thesis at a second degree level
-
Nygård, M;
Nilsen, M;
Remseth, V;
Slupphaug, Geir;
Krokan, Hans Einar.
(2002)
Uttrykk av det membran-modifiserende enzymet UDPDG i E.coli som funksjon av dyrkningsbetingelser og induksjon av DNA-skader.
[Mangler utgivernavn]
Thesis at a second degree level
2001
-
Krokan, Hans Einar;
Nilsen, Hilde.
(2001)
Base excision repair in a network of defence and tolerance.
Carcinogenesis
Academic article
-
Rudra, Parveen;
Krokan, Hans Einar.
(2001)
Cell-specific enhancement of doxorubicin toxicity in human tumour cells by docosahexaenoic acid.
Anticancer Research
Academic article
-
Krokan, Hans Einar;
Prydz, H..
(2001)
Genoverføring - administrasjonsmåter, fordeler, mulige ulemper og farer.
Tidsskrift for Den norske legeforening
Academic article
-
Krokan, Hans Einar;
Otterlei, Marit;
Nilsen, Hilde;
Kavli, Bodil;
Skorpen, Frank;
Andersen, Sonja.
(2001)
Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene.
Progress in Nucleic Acid Research and Molecular Biology
Academic article
-
Dusseau, C.;
Murray, GI;
Keenan, RA;
OKelly, T.;
Krokan, Hans Einar;
McLeod, HL.
(2001)
Analysis of uracil DNA glycosylase in human colorectal cancer.
International Journal of Oncology
Academic article
-
Kvaløy, Kirsti;
Nilsen, H.;
Steinsbekk, Kristin;
Nedal, Aina;
Monterotti, Bruno;
Akbari, Mansour.
(2001)
Sequence variation in the human uracil-DNA glycosylase (UNG) gene.
Mutation Research (DNA Repair)
Academic article
-
Krokan, Hans Einar;
Prydz, H..
(2001)
Genoverføring - administrasjonsmåter, fordeler, mulige ulemper og farer.
Tidsskrift for Den norske legeforening
Academic article
-
Prydz, Hans Peter B;
Krokan, Hans E..
(2001)
Genoverføring - Administrasjonsmåter, fordeler, mulige ulemper og farer.
TDNLF
Academic article
-
Krokan, Hans Einar.
(2001)
Kong Olav V's kreftforskningspris til Erling Seeberg.
NBS-nytt
Popular scientific article
-
Krokan, Hans Einar.
(2001)
Biologiens århundre er nå.
Fondsfinans Farmasi - Bioteknologi, Årsrapport 2000
Popular scientific article
2000
-
Nilsen, Hilde;
Steinsbekk, Kristin;
Otterlei, Marit;
Slupphaug, Geir;
Aas, Per Arne;
Krokan, Hans Einar.
(2000)
Analysis of uracil-DNA glycosylases from the murine UNG gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, Sudip S.;
Walcher, Gunter;
Jones, Garry D.;
Slupphaug, Geir;
Krokan, Hans Einar;
Blackburn, G.Michael.
(2000)
Uracil-DNA glycosylase-DNA substrate and product structures:Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Krokan, Hans Einar;
Nilsen, Hilde;
Skorpen, Frank;
Otterlei, Marit;
Slupphaug, Geir.
(2000)
Base excision repair of DNA in mammalian cells.
FEBS Letters
Academic article
-
Nilsen, Hilde;
Rosewell, Ian;
Robins, Peter;
Skjelbred, Camilla;
Andersen, Sonja;
Slupphaug, Geir.
(2000)
URACIL-DNA Glycosylase (UNG)-Deficient Mice Reveal a Primary Role of the Enzyme during DNA Replication.
Molecular Cell
Academic article
-
Krokan, Hans Einar;
Nilsen, H.;
Skorpen, Frank;
Otterlei, Marit;
Slupphaug, Geir.
(2000)
Base excision repair in mammalian cells.
FEBS Letters
Academic article
-
Otterlei, Marit;
Kavli, B;
Standal, R;
Skjelbred, Camilla;
Bharati, S;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Nilsen, Hilde;
Steinsbekk, Kristin;
Otterlei, Marit;
Slupphaug, Geir;
Aas, Per Arne;
Krokan, Hans Einar.
(2000)
Analysis of uracil-DNA glycosylases from the murine Ung-gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, S;
Walcher, G;
Jones, G.D;
Slupphaug, Geir;
Krokan, Hans Einar;
Blackburn, G.M.
(2000)
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Nilsen, Hilde;
Rosewell, I.;
Robins, P.;
Skjelbred, Camilla;
Andersen, Sonja;
Slupphaug, Geir.
(2000)
) Ung-deficient mice reveal a primary role of the uracil-DNA glycosylase enzyme during DNA replication.
Molecular Cell
Academic article
-
Otterlei, Marit;
Kavli, Bodil;
Standal, Rune;
Skjelbred, Camilla;
Bharati, Sangeeta;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Smeland, Erlend;
Prydz, Hans;
Ørstadvik, Karen Helene;
Frøland, Stig;
Aamdal, Steinar;
Myklebost, Ola.
(2000)
Genterapi Status og fremtidige muligheter innen klinisk medisin.
Lobo Grafisk AS
Non-fiction book
-
Smeland, Erlend B;
Prydz, Hans Peter B;
Ørstavik, Karen Helene;
Frøland, Stig Sophus;
Aamdal, Steinar;
Myklebost, Ola.
(2000)
Genterapi. Status og fremtidige muligheter innen klinisk medisin.
Academic chapter/article/Conference paper
1999
-
Krokan, Hans Einar;
Schønberg, Svanhild.
(1999)
Norsk studie visar att fettsyror från fisk kan døda cancerceller.
Landstidningen, Sverige
Feature article
-
Krokan, Hans Einar;
Schønberg, Svanhild.
(1999)
Omega 3 fettsyrer.
Østersundsposten
Feature article
-
Schønberg, Svanhild;
Krokan, Hans Einar.
(1999)
Fisk tar knekken på kreftceller.
Adresseavisen
Feature article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, Sture Emil.
(1999)
The origin of gut and pancreatic neuroendocrine (APUD) cells - the last word?.
Journal of Pathology
Feature article
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bhariti, Sangeeta;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1999)
Human uracil-DNA glycosylase.
NATO Advances Study Institute series. Series A, Life sciences
Academic article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, S.
(1999)
Re. Editorial entitled "The origin of gut and pancreatic neuroendocrine (APUD) cells-the last word?".
Journal of Pathology
Academic article
-
Rudra, Parveen K.;
Krokan, Hans Einar.
(1999)
Acrolein cytotoxicity and glutathione depletion in n-3 fatty acid sensitive- and resistant human tumor cells.
Anticancer Research
Academic article
-
Otterlei, Marit;
Warbrick, Emma;
Nagelhus, Toril;
Haug, Terje;
Slupphaug, Geir;
Akbari, Mansour.
(1999)
Post-replicative base excision repair in replication foci.
EMBO Journal
Academic article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar.
(1999)
The origin of gut and pancreatic neuroendocrine cells - the last word?.
Journal of Pathology
Academic article
-
Waldum, Helge;
Sandvik, Arne Kristian;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, Sture Emil.
(1999)
Letter to the Editor: Re. Editorial entitled "The origin of gut and pancreatic neuroendocrine (APUD) cells - the last word?".
Journal of Pathology
Academic article
-
Schønberg, Svanhild;
Krokan, Hans Einar.
(1999)
Fisk tar knekken på kreftceller.
Aftenposten (morgenutg. : trykt utg.)
Popular scientific article
-
Krokan, Hans Einar;
Schønberg, Svanhild;
Rudra, Parveen Kumar.
(1999)
Dreper kreft : sporet etter de krefthemmende mekanismene i Omega-3 (n-3fettsyrer) er blitt sterkere.
Teknisk Ukeblad
Popular scientific article
-
Krokan, Hans Einar.
(1999)
Kapittel 16: Vann og elektrolytter.
Cappelen Damm Høyskoleforlaget
Academic chapter/article/Conference paper
1998
-
Skorpen, Frank;
Alm, B.;
Skjelbred, Camilla;
Aas, P.A.;
Krokan, Hans Einar.
(1998)
Paracetamol increases sensitivity to ultraviolet (UV) irradiation, delays repair of the UNG-gene and recovery of RNA synthesis in HaCaT cells.
Chemico-Biological Interactions
Academic article
-
Haug, T.;
Skorpen, Frank;
Aas, P.A.;
Malm, V;
Skjelbred, Camilla;
Krokan, Hans Einar.
(1998)
Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Bharati, S.;
Krokan, Hans Einar;
Kristiansen, L;
Otterlei, Marit;
Slupphaug, Geir.
(1998)
Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar;
Parikh, S.S.;
Slupphaug, Geir;
Bharati, S;
Trainer, J.A..
(1998)
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
EMBO Journal
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(1998)
DNA-reparasjonsenzymer og deres gener.
Tidsskrift for Den norske legeforening
Academic article
-
Otterlei, Marit;
Haug, T.;
Nagelhus, T.A;
Slupphaug, Geir;
Lindmo, T.;
Krokan, Hans Einar.
(1998)
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localization signal and a strong classical mitochondrial localizations signal, respectively.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, S. Sudip;
Mol, Clifford D.;
Slupphaug, Geir;
Bharati, Sangeta;
Krokan, Hans Einar;
Yainer, John A..
(1998)
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Skorpen, Frank;
Skjelbred, Camilla;
Aas, P.A.;
Alm, B.;
Schønberg, S.A.;
Krokan, Hans Einar.
(1998)
Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus.
Mutation Research (DNA Repair)
Academic article
-
Nøding, R.;
Schønberg, S.A.;
Krokan, Hans Einar;
Bjerve, K.S..
(1998)
Effects of polyunsaturated fatty acids and their n-6 hydroperoxides on growth of five malignant cell lines and the significance of culture media.
Lipids
Academic article
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bharati, S;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1998)
Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis.
DNA damage and repair: Oxygen Radical Effects, Cellular Prote ction and Biological Consequences.
Non-fiction book
1997
-
Nilsen, H.;
Otterlei, Marit;
Haug, T.;
Solum, K.;
Nagelhus, T.A;
Skorpen, Frank.
(1997)
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.
Nucleic Acids Research (NAR)
Academic article
-
Nagelhus, T.;
Haug, T.;
Singh, K.K.;
Keshav, K.F.;
Skorpen, Frank;
Bharati, S..
(1997)
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit o replication protein A.
Journal of Biological Chemistry
Academic article
-
Schønberg, S.M.;
Rudra, P.K.;
Nøding, R.;
Bjerve, K.S;
Krokan, Hans Einar.
(1997)
Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids.
Carcinogenesis
Academic article
-
Schønberg, Svanhild A.;
Rudra, Parveen K.;
Nøding, Randi;
Skorpen, Frank;
Bjerve, Kristian S;
Krokan, Hans Einar.
(1997)
Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids.
Carcinogenesis
Academic article
-
Krokan, Hans Einar;
Standal, Rune;
Slupphaug, Geir.
(1997)
DNA glycosylase in the base excision repair of DNA.
Biochemical Journal
Academic article
-
Krokan, Hans Einar;
Standal, Rune;
Bharati, Sangeeta;
Otterlei, Marit;
Haug, Terje;
Slupphaug, Geir.
(1997)
Uracil in DNA and the family of concerved uracil DNA glycosylases.
Academic chapter/article/Conference paper
1996
-
Dizdaroglu, M.;
Karakaya, A.;
Jaruga, P.;
Slupphaug, Geir;
Krokan, Hans Einar.
(1996)
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage.
Nucleic Acids Research (NAR)
Academic article
-
Slupphaug, Geir;
Kavli, B.;
Mol, C.D.;
Arvai, A.;
Krokan, Hans Einar;
Tainer, J.A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Kavli, B.;
Slupphaug, Geir;
Mol, C.D.;
Arvai, A.S.;
Petersen, S.B.;
Tainer, J.A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Kavli, Bodil;
Slupphaug, Geir;
Mol, Clifford D.;
Arvai, Andrew S.;
Petersen, Steffen B.;
Tainer, John A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Haug, Terje;
Skorpen, Frank;
Kvaløy, Kirsti;
Eftedal, Ingrid;
Lund, Henning;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene : sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Genomics
Academic article
-
Lund, Henning;
Eftedal, Ingrid;
Haug, Terje;
Krokan, Hans Einar.
(1996)
Pseudogenes for the human uracil-DNA glycosylase on chromosomes 14 and 16.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Slupphaug, Geir;
Mol, Clifford D.;
Kavli, Bodil;
Arvai, Andrew S.;
Krokan, Hans Einar;
Tainer, John A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Dizdaroglu, Miral;
Karakaya, Asuman;
Jaruga, Pawel;
Slupphaug, Geir;
Krokan, Hans Einar.
(1996)
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage.
Nucleic Acids Research (NAR)
Academic article
-
Lehmann, A.R.;
Bridges, B.A.;
Hanawalt, P.C.;
Johnson, R.T.;
Kanaar, R.;
Krokan, Hans E..
(1996)
Workshop on processing of DNA damage.
Mutation research
Academic article
-
Lund, H.;
Eftedal, I.;
Haug, T.;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Nagelhus, T.;
Slupphaug, Geir;
Krokan, Hans Einar;
Lindmo, T..
(1996)
Fading correction for fluorescence quantitation in confocal microscopy.
Cytometry
Academic article
-
Haug, T.;
Skorpen, Frank;
Lund, H.;
Eftedal, I.;
Kvaløy, K.;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Genomics, Society and Policy
Academic article
1995
-
Slupphaug, Geir;
Eftedal, Ingrid;
Kavli, Bodil;
Bharati, Sangeeta;
Helle, Nils M;
Haug, Terje.
(1995)
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase.
Biochemistry
Academic article
-
Nilsen, Hilde;
Yazdankhah, Siamak Pour;
Eftedal, Ingrid;
Krokan, Hans Einar.
(1995)
Sequence specificity for removal of uracil from U.A pairs and U.G mismatches by uracil-DNA glycosylase from Escherichia coli, and correlation with mutational hotspots.
FEBS Letters
Academic article
1993
-
Slupphaug, Geir;
Alseth, Ingrun;
Eftedal, Ingrid;
Volden, Gunnar;
Krokan, Hans Einar.
(1993)
Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplification.
Analytical Biochemistry
Academic article
-
Slupphaug, G.;
Markussen, F.-H.;
Olsen, Lisbeth Charlotte;
Aasland, Rein;
Aarsæther, Niels;
Bakke, O..
(1993)
Human Uracil-DNA glycosylase is shared by the nucleus and the mitochondria.
Nucleic Acid Res
Academic article
-
Eftedal, Ingrid;
Guddal, Per Henrik;
Slupphaug, Geir;
Volden, Gunnar;
Krokan, Hans Einar.
(1993)
Consensus sequences for good and poor removal of uracil from double stranded DNA by uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar.
(1993)
Omega-3 fatty acids : metabolism and biological effects.
Advances in Life Sciences
Non-fiction book
-
Krokan, Hans Einar;
Valla, Svein;
Bones, Atle.
(1993)
Markørgener - sikkerhet for helse og miljø.
Direktoratet for naturforvaltning
Non-fiction book
-
Krokan, Hans Einar;
Bjerve, Kristian S;
Mørk, E..
(1993)
The enteral bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro.
Biochimica et Biophysica Acta
Academic article
1992
-
Krokan, Hans Einar.
(1992)
Expression of O(6)-methylguanine - DNA methyltransferase and uracilDNA lycosylase in human placentae from smokers and non-smokers.
Carcinogenesis
Academic article
-
Olsen, Lisbeth Charlotte;
Aasland, Rein;
Krokan, H. E.;
Helland, Dag Emil.
(1992)
Human uracil DNA glycosylase cDNA complements E.coli ung mutants.
Nucleic Acid Res
Academic article
1991
-
Slupphaug, G.;
Olsen, Lisbeth Charlotte;
Helland, Dag Emil;
Aasland, Rein;
Krokan, H. E..
(1991)
Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil- DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
1990
-
Aasland, Rein;
Olsen, Lisbeth Charlotte;
Spurr, N. K.;
Krokan, H. E.;
Helland, Dag Emil.
(1990)
Chromosomal assignment of Human Uracil-DNA Glycosylase to Chromosome 12.
Genomics
Academic article
1978
-
Wist, Erik;
Krokan, Hans E..
(1978)
Preservation by glycerol of DNA synthetic capacity of isolated HeLa cell nuclei during long term storage at low temperature.
Experimental Cell Research
Academic article
-
Wist, Erik;
Undhjem, O;
Krokan, Hans E..
(1978)
Accumulation of small fragments of DNA in isolated HeLa cell nuclei due to transient incorporation of dUMP.
Biochimica et Biophysica Acta
Academic article
1977
-
Krokan, Hans E.;
Wist, Erik;
Prydz, Hans Peter B.
(1977)
DNA replication intermediates in whole HeLa cells and isolated nuclei.
Biochimica et Biophysica Acta
Academic article
-
Krokan, Hans E.;
Wist, Erik;
Prydz, Hans Peter B.
(1977)
Effect of cytosol on DNA synthesis in isolated nuclei.
Biochemical and Biophysical Research Communications - BBRC
Academic article
1976
-
Wist, Erik;
Krokan, Hans E.;
Prydz, Hans Peter B.
(1976)
Effect of 1-beta-D-arabionsyl-cytosine-triphosphate on DNA synthesis in HeLa cell nuclei.
Biochemistry
Academic article
Journal publications
-
Lefol, Yohan Pierre;
Korfage, Tom;
Mjelle, Robin;
Prebensen, Christian Haugland;
Lüders, Torben;
Müller, Bruno.
(2023)
TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data.
NAR Genomics and Bioinformatics
Academic article
-
Bonagas, Nadilly;
Gustafsson, Nina M. S.;
Henriksson, Martin;
Marttila, Petra;
Gustafsson, Robert;
Wiita, Elisée.
(2022)
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Nature Cancer
Academic article
-
Olinski, Ryszard;
Slupphaug, Geir;
Foksinski, Marek;
Krokan, Hans Einar.
(2021)
Genomic Uracil and Aberrant Profile of Demethylation Intermediates in Epigenetics and Hematologic Malignancies.
International Journal of Molecular Sciences
Academic article
-
Visnes, Torkild;
Benitez-Buelga, Carlos;
Cázares-Körner, Armando;
Sanjiv, Kumar;
Hanna, Bishoy M F;
Mortusewicz, Oliver.
(2020)
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Research (NAR)
Academic article
-
Boeckemeier, L;
Kraehenbuehl, R;
Keszthelyi, A;
Gasasira, MU;
Vernon, EG;
Beardmore, R.
(2020)
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Science Advances
Academic article
-
Sarno, Antonio;
Lundbæk, Marie Benner;
Liabakk, Nina-Beate;
Aas, Per Arne;
Mjelle, Robin;
Hagen, Lars.
(2019)
Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.
Nucleic Acids Research (NAR)
Academic article
-
Visnes, Torkild;
Armando, Cazares-Körner;
Wenjing, Hao;
Wallner, Olov;
Masuyer, Geoffrey;
Loseva, Olga.
(2018)
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science
Academic article
-
Wang, Yufei;
McKay, James D.;
Rafnar, Thorunn;
Wang, Zhaoming;
Timofeeva, Maria N.;
Broderick, Peter.
(2017)
Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (Nature Genetics (2014) 46 (736-741)).
Nature Genetics
Errata
-
Alsøe, Lene;
Sarno, Antonio;
Carracedo Huroz, Sergio;
Domanska, Diana Ewa;
Dingler, Felix;
Lirussi, Lisa.
(2017)
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Scientific Reports
Academic article
-
Rasmussen, Erik;
Vågbø, Cathrine Broberg;
Münch, Daniel;
Krokan, Hans Einar;
Klungland, Arne;
Amdam, Gro Vang.
(2016)
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates.
Biochemistry and Biophysics Reports
Academic article
-
Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Academic article
-
Xue, JH;
Xu, GF;
Gu, TP;
Chen, GD;
Han, BB;
Xu, ZM.
(2016)
Uracil-DNA glycosylase UNG promotes tet-mediated DNA demethylation.
Journal of Biological Chemistry
Academic article
-
Helander, Linda;
Sharma, Animesh;
Krokan, Hans Einar;
Plaetzer, Kristjan;
Krammer, Barbara;
Tortik, Nicole.
(2016)
Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins.
Molecular Biosystems
Academic article
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Academic article
-
Brenner, Darren. R.;
Amos, Christopher I.;
Brhane, Yonathan;
Timofeeva, Maria N.;
Caporaso, Neil;
Wang, Yufei.
(2015)
Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.
Carcinogenesis
Academic article
-
Mjelle, Robin;
Hegre, Siv Anita;
Aas, Per Arne;
Slupphaug, Geir;
Drabløs, Finn;
Sætrom, Pål.
(2015)
Cell cycle regulation of human DNA repair and chromatin remodeling genes.
DNA Repair
Academic article
-
Wang, Yufei;
McKay, JD;
Rafnar, T;
Wang, Z;
Timofeeva, MN;
Broderick, P.
(2014)
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
Nature Genetics
Academic article
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Academic article
-
Hu, Yi;
Ericsson, Ida;
Doseth, Berit;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2014)
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors.
Experimental Cell Research
Academic article
-
Wallenius, Anders;
Hauser, Jannek;
Aas, Per Arne;
Sarno, Antonio;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2014)
Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification.
Molecular Immunology
Academic article
-
Zdzalik, Daria;
Vågbø, Cathrine Broberg;
Kirpekar, F;
Davydova, Erna;
Puścian, Alicja;
Maciejewska, Agnieszka M..
(2014)
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities.
PLOS ONE
Academic article
-
Helander, Linda;
Krokan, Hans Einar;
Johnsson, Anders Carl G.;
Gederaas, Odrun Arna;
Plaetzer, Kristjan.
(2014)
Red versus blue light illumination in hexyl 5-aminolevulinate photodynamic therapy: the influence of light color and irradiance on the treatment outcome in vitro.
Journal of Biomedical Optics
Academic article
-
Bjørngaard, Johan Håkon;
Gunnell, David;
Gabrielsen, Maiken Elvestad;
Davey Smith, George;
Skorpen, Frank;
Krokan, Hans Einar.
(2013)
The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study.
Psychological Medicine
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Ericsson, Ida;
Galashevskaya, Anastasia;
Sarno, Antonio;
Aas, Per Arne.
(2013)
Genomic uracil - potent mutagen but normal intermediate in adaptive immunity.
The FEBS Journal
Abstract
-
Hu, Yi;
Ericsson, Ida;
Torseth, Kathrin;
Methot, Stephen;
Sundheim, Ottar;
Liabakk, Nina-Beate.
(2013)
A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
Journal of Molecular Biology (JMB)
Academic article
-
Zheng, Guanqun;
Dahl, John Arne;
Niu, Yamei;
Fedorcsak, Peter;
Huang, Chun-Min;
Li, Charles J..
(2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.
Molecular Cell
Academic article
-
Vågbø, Cathrine Broberg;
Svaasand, Eva Kathrine;
Aas, Per Arne;
Krokan, Hans Einar.
(2013)
Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Bjørås, Magnar.
(2013)
Base Excision Repair.
Cold Spring Harbor Perspectives in Biology
Academic article
-
Galashevskaya, Anastasia;
Sarno, Antonio;
Vågbø, Cathrine Broberg;
Aas, Per Arne;
Hagen, Lars;
Slupphaug, Geir.
(2013)
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.
DNA Repair
Academic article
-
Hegre, Siv Anita;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Otterlei, Marit;
Krokan, Hans Einar.
(2013)
Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase.
DNA Repair
Academic article
-
Diaz, Javier Pena;
Hegre, Siv Anita;
Anderssen, Endre;
Aas, Per Arne;
Mjelle, Robin;
Gilfillan, Gregor Duncan.
(2013)
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.
Nucleic Acids Research (NAR)
Academic article
-
Gabrielsen, Maiken Elvestad;
Romundstad, Pål Richard;
Langhammer, Arnulf;
Krokan, Hans Einar;
Skorpen, Frank.
(2013)
Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56 307 individuals from the HUNT study in Norway.
European Journal of Human Genetics
Academic article
-
Krokan, Hans Einar.
(2012)
A life in DNA repair-And beyond.
DNA Repair
Editorial
-
Torseth, Kathrin;
Doseth, Berit;
Hagen, Lars;
Olaisen, Camilla;
Liabakk, Nina-Beate;
Græsmann, Heidi.
(2012)
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.
DNA Repair
Academic article
-
Doseth, Berit;
Ekre, Cecilie;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2012)
Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
DNA Repair
Academic article
-
Krokan, Hans Einar.
(2012)
To Repair and Protect.
International Innovation
Popular scientific article
-
Krokan, Hans Einar.
(2012)
Stable Genomes and DNA Repair.
International Innovation
Popular scientific article
-
Krokan, Hans Einar.
(2012)
The Essentials of DNA Repair.
Public Service Review: European Union
Popular scientific article
-
Timofeeva, MN;
Hung, RJ;
Rafnar, T;
Christiani, DC;
Field, JK;
Bickeboller, H.
(2012)
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
Human Molecular Genetics
Academic article
-
Meza, Trine Johansen;
Moen, Marivi;
Vågbø, Cathrine Broberg;
Krokan, Hans Einar;
Klungland, Arne;
Grini, Paul Eivind.
(2012)
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.
Nucleic Acids Research (NAR)
Academic article
-
Akbari, Mansour;
Krokan, Hans Einar.
(2012)
Base excision repair efficiency and mechanism in nuclear extracts are influenced by the ratio between volume of nuclear extraction buffer and nuclei-Implications for comparative studies.
Mutation research
Academic article
-
Kazma, R;
Babron, MC;
Gaborieau, Valerie;
Génin, E;
Brennan, P;
Hung, Rayjean J..
(2012)
Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium.
Carcinogenesis
Academic article
-
Johnson, Matthew P;
Brennecke, Shaun P.;
Iversen, Ann-Charlotte;
East, Christine;
Olsen, Guro Dalheim;
Kent, Jack W.
(2012)
Genome-wide association scans identify novel maternal susceptibility loci for preeclampsia.
Pregnancy Hypertension
Abstract
-
Robertson, Adam Brian;
Dahl, John Arne;
Vågbø, Cathrine Broberg;
Tripathi, P;
Krokan, Hans Einar;
Klungland, Arne.
(2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Research (NAR)
Academic article
-
Arum, Carl-Jørgen;
Gederaas, Odrun Arna;
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Hjelde, Astrid;
Krokan, Hans Einar.
(2011)
Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action.
Journal of Biomedical Optics
Academic article
-
Leihne, VIbeke;
Kirpekar, F;
Vågbø, Cathrine Broberg;
Van den Born, Erwin;
Krokan, Hans Einar;
Grini, Paul Eivind.
(2011)
Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.
Nucleic Acids Research (NAR)
Academic article
-
Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR)
Academic article
-
Hanssen-Bauer, Audun;
Solvang-Garten, Karin;
Sundheim, Ottar;
Diaz, Javier Pena;
Andersen, Sonja Benedikte;
Slupphaug, Geir.
(2011)
XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage.
Environmental and Molecular Mutagenesis
Academic article
-
Sletta, Håvard;
Klinkenberg, Geir;
Winnberg, Asgeir;
Kvitvang, Hans Fredrik Nyvold;
Nilsen, Marianne Bakke;
Krokan, Hans Einar.
(2011)
A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants.
Journal of Microbiological Methods
Academic article
-
Doseth, Berit;
Visnes, Torkild;
Wallenius, Anders;
Ericsson, Ida;
Sarno, Antonio;
Pettersen, Henrik Sahlin.
(2011)
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE.
Journal of Biological Chemistry
Academic article
-
Van den Born, Erwin;
Vågbø, Cathrine Broberg;
Songe-Møller, Lene;
Leihne, VIbeke;
Lien, Guro Flor;
Leszczynska, G.
(2011)
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.
Nature Communications
Academic article
-
Baglo, Yan;
Sousa, Mirta;
Slupphaug, Geir;
Hagen, Lars;
Håvåg, Sissel;
Helander, Linda.
(2011)
Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways.
Photochemical and Photobiological Sciences
Academic article
-
Monsen, Vivi A Talstad;
Sundheim, Ottar;
Aas, Per Arne;
Westbye, Marianne Pedersen;
Sousa, Mirta;
Slupphaug, Geir.
(2010)
Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar.
(2010)
Advarer mot biodiesel i fossilt diesel: Svært mange kan bli syke.
Teknisk Ukeblad
Interview Journal
-
Songe-Møller, Lene;
Van den Born, Erwin;
Leihne, V;
Vågbø, Cathrine Broberg;
Kristoffersen, T;
Krokan, Hans Einar.
(2010)
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding.
Molecular and Cellular Biology
Academic article
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Størvold, Gro Leite;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2010)
DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells.
Nutrition and Cancer
Academic article
-
Akbari, Mansour;
Solvang-Garten, Karin;
Hanssen-Bauer, Audun;
Lieske, Nora V.;
Pettersen, Henrik P Sahlin;
Pettersen, Grete Klippenvåg.
(2010)
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Otterlei, Marit;
Akbari, M.;
Slupphaug, Geir;
Aas, Per Arne.
(2010)
DNA repair and cancer.
European Journal of Cancer
Abstract
-
Visnes, Torkild;
Doseth, Berit;
Pettersen, Henrik Sahlin;
Hagen, Lars;
Sousa, Mirta;
Akbari, Mansour.
(2009)
Uracil in DNA and its processing by different DNA glycosylases.
Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic literature review
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2009)
The Antiproliferative Effect of EPA in HL60 Cells is Mediated by Alterations in Calcium Homeostasis.
Lipids
Academic article
-
Størvold, Gro Leite;
Fleten, Karianne Giller;
Olsen, Cathrine Goberg;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2009)
Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells.
Lipids
Academic article
-
Gilljam, Karin Margaretha;
Feyzi, Emadoldin;
Aas, Per Arne;
Sousa, Mirta;
Müller, Rebekka;
Vågbø, Cathrine Broberg.
(2009)
Identification of a novel, widespread, and functionally important PCNA-binding motif.
Journal of Cell Biology
Academic article
-
Akbari, Mansour;
Diaz, Javier Pena;
Andersen, Sonja Benedikte;
Liabakk, Nina-Beate;
Otterlei, Marit;
Krokan, Hans Einar.
(2009)
Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity.
DNA Repair
Academic article
-
Aas, Per Arne;
Diaz, Javier Pena;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Skorpen, Frank.
(2009)
Overexpression of transcription factor AP-2 stimulates the P-A promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression.
DNA Repair
Academic article
-
Landi, MT;
Chatterjee, N;
Yu, K;
Goldin, LR;
Goldstein, AM;
Rotunno, M.
(2009)
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.
American Journal of Human Genetics
Academic article
-
Hung, RJ;
Mckay, J;
Gaborieau, V;
Boffetta, P;
Chu, C;
Field, JK.
(2008)
Detecting new genes for tobacco-related cancers - genomewide association study of lung cancer.
European Journal of Cancer
Abstract
-
Akbari, Mansour;
Krokan, Hans Einar.
(2008)
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging.
Mechanisms of Ageing and Development
Academic literature review
-
Andersen, Sonja Benedikte;
Krokan, Hans Einar;
Baar, Cecilie Christensen;
Rakvag, Trude Teoline;
Laugsand, Eivor Alette;
Kvam, Tor-Morten.
(2008)
Identification of an alternative, putative promoter and new alternatively spliced transcripts from the human µ opioid receptor gene, OPRM1.
Palliative Medicine
Abstract
-
Heath, SC;
Gut, IG;
Brennan, P;
Mckay, JD;
Bencko, V;
Fabianova, E.
(2008)
Investigation of the fine structure of European populations with applications to disease association studies.
European Journal of Human Genetics
Academic article
-
McKay, JD;
Mckay, JD;
Hung, RJ;
Gaborieau, V;
Boffetta, Paolo;
Chabrier, Amelie.
(2008)
Lung cancer susceptibility locus at 5p15.33.
Nature Genetics
Academic article
-
Slagsvold, Jens Erik;
Pettersen, Caroline Hild;
Follestad, Turid;
Krokan, Hans Einar;
Schønberg, Svanhild Margrethe Arentz.
(2008)
The antiproliferative effect of EPA in HL60 cells is mediated by alterations in calcium homeostasis.
Lipids
Academic article
-
Hung, RJ;
Mckay, JD;
Gaborieau, V;
Boffetta, P;
Hashibe, M;
Zaridze, D.
(2008)
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
Nature
Academic article
-
Bathen, Tone Frost;
Holmgren, Kristin;
Lundemo, Anne Gøril;
Hjelstuen, Mari H;
Krokan, Hans Einar;
Gribbestad, Ingrid S.
(2008)
Omega-3 Fatty Acids Supress Growth of SW620 Human Colon Cancer Xenografts in Nude Mice.
Anticancer Research
Academic article
-
Akbari, Mansour;
Visnes, Torkild;
Krokan, Hans Einar;
Otterlei, Marit.
(2008)
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis.
DNA Repair
Academic article
-
Sundheim, Ottar;
Talstad, Vivi A;
Vågbø, Cathrine Broberg;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
AlkB demethylases flip out in different ways.
DNA Repair
Academic article
-
Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry
Academic article
-
Visnes, Torkild;
Akbari, Mansour;
Hagen, Lars;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
The rate of base excision repair of uracil is controlled by the initiating glycosylase.
DNA Repair
Academic article
-
Krokan, Hans Einar.
(2008)
NBS 40 år.
NBS-nytt
Popular scientific article
-
Hagen, Lars;
Kavli, Bodil Merete;
Sousa, Mirta;
Torseth, Kathrin;
Liabakk, Nina-Beate;
Sundheim, Ottar.
(2008)
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
EMBO Journal
Academic article
-
Jakobsen, CH;
Pettersen, Caroline Hild;
Størvold, Gro Leite;
Bremseth, Hilde;
Follestad, Turid;
Sand, Kristin.
(2008)
DHA induces ER stress and growth arrest in human colon cancer cells: association with cholesterol and calcium homeostasis.
Journal of Lipid Research
Academic article
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Arum, Carl-Jørgen;
Hjelde, Astrid;
Zhao, Chun-Mei.
(2008)
Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy.
Journal of Biomedical Optics
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
Repair of small base lesions in DNA - From molecular biology to phenotype - Preface.
DNA Repair
Editorial
-
Sousa, Mirta;
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
DNA-uracil and human pathology.
Molecular Aspects of Medicine
Academic literature review
-
Feyzi, Emadoldin;
Aas, Per Arne;
Sundheim, Ottar;
Westbye, Marianne;
Vågbø, Cathrine Broberg;
Otterlei, Marit.
(2007)
RNA Base Damage and Repair.
Current Pharmaceutical Biotechnology
Academic literature review
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2007)
Repair of small base lesions in DNA- from molecular biology to phenotype.
DNA Repair
Abstract
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Akbari, Mansour;
Visnes, Torkild;
Pettersen, Henrik P Sahlin;
Sundheim, Ottar.
(2007)
Repair og uracil in DNA by UNG2 and SMUG1 - an update.
DNA Repair
Abstract
-
Pettersen, Henrik P Sahlin;
Sundheim, Ottar;
Gilljam, Karin Margaretha;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2007)
Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.
Nucleic Acids Research (NAR)
Academic article
-
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
Uracil in DNA - General mutagen, but normal intermediate in acquired immunity.
DNA Repair
Academic article
-
Akbari, Mansour;
Otterlei, Marit;
Pena-Diaz, J;
Krokan, Hans Einar.
(2007)
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress.
Neuroscience
Academic article
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Arum, Carl-Jørgen;
Krokan, Hans Einar;
Chen, Duan.
(2006)
Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy.
Lasers in Surgery and Medicine
Abstract
-
Hagen, Lars;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2006)
Genomic uracil and human disease.
Experimental Cell Research
Academic literature review
-
Krokan, Hans Einar;
Akbari, Mansour;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Ericsson, Madelene.
(2006)
Base excision repair proteins in cancer prevention and acquired immune responses.
The FEBS Journal
Abstract
-
Ringvoll, Jeanette;
Ringvoll, Jeanette;
Nordstrand, Line M.;
Vågbø, Cathrine Broberg;
Vagbo, CB;
Talstad, Vivi.
(2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
EMBO Journal
Academic article
-
Sundheim, Ottar;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Mittelstedt, L.Mirta;
Talstad, Vivi;
Aas, Per Arne.
(2006)
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
EMBO Journal
Academic article
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Krokan, Hans Einar.
(2006)
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress.
Neuroscience
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2006)
Preface.
DNA Repair
Academic article
-
Schønberg, Svanhild Margrethe Arentz;
Lundemo, Anne Gøril;
Fladvad, Torill;
Holmgren, Kristin;
Bremseth, Hilde;
Nilsen, Asbjørn Magne.
(2006)
Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory element-binding protein 1.
The FEBS Journal
Academic article
-
Hjelde, Astrid;
Gederaas, Odrun Arna;
Krokan, Hans Einar;
Brubakk, Alf O.
(2005)
Lack of effect of hyperoxia on photodynamic therapy and lipid peroxidation in three different cancer cell lines.
Medical Science Monitor
Academic article
-
Kavli, Bodil Merete;
Andersen, Sonja Benedikte;
Otterlei, Marit;
Liabakk, Nina-Beate;
Imai, K;
Fischer, A.
(2005)
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
Journal of Experimental Medicine (JEM)
Academic article
-
Gederaas, Odrun Arna;
Schønberg, Svanhild Margrethe Arentz;
Ramstad, Ståle;
Berg, Kristian;
Johnsson, Anders Carl G.;
Krokan, Hans Einar.
(2005)
Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization.
Photochemical and Photobiological Sciences
Academic article
-
Andersen, Sonja Benedikte;
Heine, T;
Sneve, Ragnhild;
Kønig, Imbritt;
Krokan, Hans Einar;
Epe, B.
(2005)
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.
Carcinogenesis
Academic article
-
Andersen, Sonja Benedikte;
Ericsson, Maria Elisabeth Madelene;
Dai, HY;
Diaz, Javier Pena;
Slupphaug, Geir;
Nilsen, H.
(2005)
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
DNA Repair
Academic article
-
Auerbach, Paul;
Bennett, Richard A.O.;
Bailey, Elisabeth A.;
Krokan, Hans Einar;
Demple, Bruce.
(2005)
Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Schønberg, Svanhild Margrethe Arentz;
Jakobsen, Caroline Hild;
Bremseth, Hilde;
Olsen, Karina Standahl;
Lundemo, Anne Gøril;
Follestad, Turid.
(2005)
Endoplasmic reticulum stress induced by DHA leads to growth arrest of human colon cancer cells.
Chemistry and Physics of Lipids
Academic article
-
Akbari, Mansour;
Hansen, Marianne Dore;
Halgunset, Jostein;
Skorpen, Frank;
Krokan, Hans Einar.
(2005)
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.
Journal of Molecular Diagnostics
Academic article
-
Rakvag, Trude Teoline;
Klepstad, Pål;
Baar, Cecilie Christensen;
Kvam, Tor-Morten;
Dale, Ola;
Kaasa, Stein.
(2005)
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Pain
Academic article
-
Andersen, S;
Heine, T;
Sneve, Ragnhild;
Konig, I;
Krokan, HE;
Epe, B.
(2005)
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.
Carcinogenesis
Academic article
-
Andersen, S;
Ericsson, M;
DAI, H;
Peña-Diaz, J;
Slupphaug, G;
Nilsen, Hilde.
(2005)
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
DNA Repair
Academic article
-
Krokan, Hans Einar.
(2004)
Molecular and functional interactions in macromolecular repair.
European Journal of Biochemistry (EJB)
Abstract
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2004)
Novel aspects of macromolecular repair and relationship to human disease.
Journal of Molecular Medicine
Academic literature review
-
Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair
Academic literature review
-
Kvam, TM;
Baar, Cecilie Christensen;
Raakvag, Trude Teoline;
Kaasa, Stein;
Krokan, Hans Einar;
Skorpen, Frank.
(2004)
Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing.
Journal of Molecular Medicine
Academic article
-
Klepstad, Pål;
Rakvag, TT;
Kaasa, Stein;
Holthe, Monica;
Dale, Ola;
Borchgrevink, Petter Chr..
(2004)
The 118 A>G polymorphism in the human mu-opioid receptor gene may increase morphins requirements in patients with pain caused by malignant disease.
Acta Anaesthesiologica Scandinavica
Academic article
-
Akbari, Mansour;
Skjelbred, C;
Folling, I;
Sagen, J;
Krokan, Hans Einar.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
-
Diaz, Javier Pena;
Akbari, Mansour;
Sundheim, Ottar;
Farez-Vidal, ME;
Andersen, S;
Sneve, R.
(2004)
Trypanosoma cruzi contains a single detectable uracil-DNA glycosylase and repairs uracil exclusively via short patch base excision repair.
Journal of Molecular Biology (JMB)
Academic article
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Aas, Per Arne;
Kavli, Bodil;
Liabakk, Nina-Beate.
(2004)
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.
Nucleic Acids Research (NAR)
Academic article
-
Akbari, M;
Skjelbred, C;
Folling, I;
Sagen, Jørn V.;
Krokan, HE.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA (Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
-
Klepstad, Pål;
Rakvag, Trude Teoline;
Kaasa, Stein;
Holthe, Monica;
Dale, Ola;
Borchgrevink, Petter Chr..
(2004)
The 118 A>G polymorphism in the human µ-opioidreceptor gene may increase morphine requrements in patients with pain caused by malignant disease.
Acta Anaesthesiologica Scandinavica
Academic article
-
Akbari, M;
Skjelbred, C;
Følling, Ivar;
Sagen, J;
Krokan, H E.
(2004)
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA Leu (UUR)) applied to a Norwegian family with diabetes mellitus and hearing loss.
Scandinavian Journal of Clinical and Laboratory Investigation
Academic article
-
Holthe, M.;
Rakvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2003)
Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.
The Pharmacogenomics Journal
Academic article
-
Slupphaug, Geir;
Kavli, Bodil;
Krokan, Hans Einar.
(2003)
Interacting pathways that prevent and repair oxidative DNA damage.
Mutation Research (DNA Repair)
Academic article
-
Nilsen, Hilde;
Stamp, G;
Andersen, Sonja;
Hrivnak, G;
Krokan, Hans Einar;
Lindahl, T.
(2003)
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.
Oncogene
Academic article
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature
Academic article
-
Imai, K;
Slupphaug, Geir;
Lee, W-I;
Revy, P;
Nonoyama, S;
Catalan, N.
(2003)
Uracil-DNA glycosylase deficiency profoundly impairs immunoglobulin class switch.
Nature Immunology
Academic article
-
Holthe, Monica;
Råkvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2003)
Identification of 10 novel single nucleotide polymorphisms and analysis of their relevance to morphine glucuronidation.
The Pharmacogenomics Journal
Academic article
-
Holthe, Monica;
Klepstad, Pål;
Zahlsen, Kolbjørn;
Borchgrevink, Petter Chr.;
Hagen, Lars;
Dale, Ola.
(2002)
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1a1*28 polymorphisms in cancer patients on chronic morphine therapy.
European Journal of Clinical Pharmacology
Academic article
-
Krokan, Hans Einar;
Drabløs, Finn;
Slupphaug, Geir.
(2002)
Uracil in DNA, occurrence, consequences and repair.
Oncogene
Academic article
-
Kavli, Bodil;
Sundheim, Ottar;
Akbari, Mansour;
Otterlei, Marit;
Nilsen, Hilde;
Skorpen, Frank.
(2002)
hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup.
Journal of Biological Chemistry
Academic article
-
Krokan, Hans Einar.
(2002)
Fromprotein folding to new enzymes.
Tidsskrift for Den norske legeforening
Academic article
-
Holthe, Monica;
Råkvåg, Trude Teoline;
Klepstad, Pål;
Idle, Jefrrey R.;
Kaasa, Stein;
Krokan, Hans Einar.
(2002)
Sequence variationin the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphins (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.
The Pharmacogenomics Journal
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(2002)
Damage and repair of DNA in mammalian cells-emphasis on oxidative damage. Proceedings from International Symposium "Natural Ionising Radiation and Health".
Det Norske Videnskaps-Akademi : proceedings
Academic article
-
Krokan, Hans Einar;
Nilsen, Hilde.
(2001)
Base excision repair in a network of defence and tolerance.
Carcinogenesis
Academic article
-
Rudra, Parveen;
Krokan, Hans Einar.
(2001)
Cell-specific enhancement of doxorubicin toxicity in human tumour cells by docosahexaenoic acid.
Anticancer Research
Academic article
-
Krokan, Hans Einar;
Prydz, H..
(2001)
Genoverføring - administrasjonsmåter, fordeler, mulige ulemper og farer.
Tidsskrift for Den norske legeforening
Academic article
-
Krokan, Hans Einar;
Otterlei, Marit;
Nilsen, Hilde;
Kavli, Bodil;
Skorpen, Frank;
Andersen, Sonja.
(2001)
Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene.
Progress in Nucleic Acid Research and Molecular Biology
Academic article
-
Dusseau, C.;
Murray, GI;
Keenan, RA;
OKelly, T.;
Krokan, Hans Einar;
McLeod, HL.
(2001)
Analysis of uracil DNA glycosylase in human colorectal cancer.
International Journal of Oncology
Academic article
-
Kvaløy, Kirsti;
Nilsen, H.;
Steinsbekk, Kristin;
Nedal, Aina;
Monterotti, Bruno;
Akbari, Mansour.
(2001)
Sequence variation in the human uracil-DNA glycosylase (UNG) gene.
Mutation Research (DNA Repair)
Academic article
-
Krokan, Hans Einar;
Prydz, H..
(2001)
Genoverføring - administrasjonsmåter, fordeler, mulige ulemper og farer.
Tidsskrift for Den norske legeforening
Academic article
-
Prydz, Hans Peter B;
Krokan, Hans E..
(2001)
Genoverføring - Administrasjonsmåter, fordeler, mulige ulemper og farer.
TDNLF
Academic article
-
Krokan, Hans Einar.
(2001)
Kong Olav V's kreftforskningspris til Erling Seeberg.
NBS-nytt
Popular scientific article
-
Krokan, Hans Einar.
(2001)
Biologiens århundre er nå.
Fondsfinans Farmasi - Bioteknologi, Årsrapport 2000
Popular scientific article
-
Nilsen, Hilde;
Steinsbekk, Kristin;
Otterlei, Marit;
Slupphaug, Geir;
Aas, Per Arne;
Krokan, Hans Einar.
(2000)
Analysis of uracil-DNA glycosylases from the murine UNG gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, Sudip S.;
Walcher, Gunter;
Jones, Garry D.;
Slupphaug, Geir;
Krokan, Hans Einar;
Blackburn, G.Michael.
(2000)
Uracil-DNA glycosylase-DNA substrate and product structures:Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Krokan, Hans Einar;
Nilsen, Hilde;
Skorpen, Frank;
Otterlei, Marit;
Slupphaug, Geir.
(2000)
Base excision repair of DNA in mammalian cells.
FEBS Letters
Academic article
-
Nilsen, Hilde;
Rosewell, Ian;
Robins, Peter;
Skjelbred, Camilla;
Andersen, Sonja;
Slupphaug, Geir.
(2000)
URACIL-DNA Glycosylase (UNG)-Deficient Mice Reveal a Primary Role of the Enzyme during DNA Replication.
Molecular Cell
Academic article
-
Krokan, Hans Einar;
Nilsen, H.;
Skorpen, Frank;
Otterlei, Marit;
Slupphaug, Geir.
(2000)
Base excision repair in mammalian cells.
FEBS Letters
Academic article
-
Otterlei, Marit;
Kavli, B;
Standal, R;
Skjelbred, Camilla;
Bharati, S;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Nilsen, Hilde;
Steinsbekk, Kristin;
Otterlei, Marit;
Slupphaug, Geir;
Aas, Per Arne;
Krokan, Hans Einar.
(2000)
Analysis of uracil-DNA glycosylases from the murine Ung-gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, S;
Walcher, G;
Jones, G.D;
Slupphaug, Geir;
Krokan, Hans Einar;
Blackburn, G.M.
(2000)
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Nilsen, Hilde;
Rosewell, I.;
Robins, P.;
Skjelbred, Camilla;
Andersen, Sonja;
Slupphaug, Geir.
(2000)
) Ung-deficient mice reveal a primary role of the uracil-DNA glycosylase enzyme during DNA replication.
Molecular Cell
Academic article
-
Otterlei, Marit;
Kavli, Bodil;
Standal, Rune;
Skjelbred, Camilla;
Bharati, Sangeeta;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Krokan, Hans Einar;
Schønberg, Svanhild.
(1999)
Norsk studie visar att fettsyror från fisk kan døda cancerceller.
Landstidningen, Sverige
Feature article
-
Krokan, Hans Einar;
Schønberg, Svanhild.
(1999)
Omega 3 fettsyrer.
Østersundsposten
Feature article
-
Schønberg, Svanhild;
Krokan, Hans Einar.
(1999)
Fisk tar knekken på kreftceller.
Adresseavisen
Feature article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, Sture Emil.
(1999)
The origin of gut and pancreatic neuroendocrine (APUD) cells - the last word?.
Journal of Pathology
Feature article
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bhariti, Sangeeta;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1999)
Human uracil-DNA glycosylase.
NATO Advances Study Institute series. Series A, Life sciences
Academic article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, S.
(1999)
Re. Editorial entitled "The origin of gut and pancreatic neuroendocrine (APUD) cells-the last word?".
Journal of Pathology
Academic article
-
Rudra, Parveen K.;
Krokan, Hans Einar.
(1999)
Acrolein cytotoxicity and glutathione depletion in n-3 fatty acid sensitive- and resistant human tumor cells.
Anticancer Research
Academic article
-
Otterlei, Marit;
Warbrick, Emma;
Nagelhus, Toril;
Haug, Terje;
Slupphaug, Geir;
Akbari, Mansour.
(1999)
Post-replicative base excision repair in replication foci.
EMBO Journal
Academic article
-
Waldum, Helge;
Sandvik, AK;
Angelsen, Anders;
Krokan, Hans Einar.
(1999)
The origin of gut and pancreatic neuroendocrine cells - the last word?.
Journal of Pathology
Academic article
-
Waldum, Helge;
Sandvik, Arne Kristian;
Angelsen, Anders;
Krokan, Hans Einar;
Falkmer, Sture Emil.
(1999)
Letter to the Editor: Re. Editorial entitled "The origin of gut and pancreatic neuroendocrine (APUD) cells - the last word?".
Journal of Pathology
Academic article
-
Schønberg, Svanhild;
Krokan, Hans Einar.
(1999)
Fisk tar knekken på kreftceller.
Aftenposten (morgenutg. : trykt utg.)
Popular scientific article
-
Krokan, Hans Einar;
Schønberg, Svanhild;
Rudra, Parveen Kumar.
(1999)
Dreper kreft : sporet etter de krefthemmende mekanismene i Omega-3 (n-3fettsyrer) er blitt sterkere.
Teknisk Ukeblad
Popular scientific article
-
Skorpen, Frank;
Alm, B.;
Skjelbred, Camilla;
Aas, P.A.;
Krokan, Hans Einar.
(1998)
Paracetamol increases sensitivity to ultraviolet (UV) irradiation, delays repair of the UNG-gene and recovery of RNA synthesis in HaCaT cells.
Chemico-Biological Interactions
Academic article
-
Haug, T.;
Skorpen, Frank;
Aas, P.A.;
Malm, V;
Skjelbred, Camilla;
Krokan, Hans Einar.
(1998)
Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Bharati, S.;
Krokan, Hans Einar;
Kristiansen, L;
Otterlei, Marit;
Slupphaug, Geir.
(1998)
Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar;
Parikh, S.S.;
Slupphaug, Geir;
Bharati, S;
Trainer, J.A..
(1998)
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
EMBO Journal
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir.
(1998)
DNA-reparasjonsenzymer og deres gener.
Tidsskrift for Den norske legeforening
Academic article
-
Otterlei, Marit;
Haug, T.;
Nagelhus, T.A;
Slupphaug, Geir;
Lindmo, T.;
Krokan, Hans Einar.
(1998)
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localization signal and a strong classical mitochondrial localizations signal, respectively.
Nucleic Acids Research (NAR)
Academic article
-
Parikh, S. Sudip;
Mol, Clifford D.;
Slupphaug, Geir;
Bharati, Sangeta;
Krokan, Hans Einar;
Yainer, John A..
(1998)
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Skorpen, Frank;
Skjelbred, Camilla;
Aas, P.A.;
Alm, B.;
Schønberg, S.A.;
Krokan, Hans Einar.
(1998)
Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus.
Mutation Research (DNA Repair)
Academic article
-
Nøding, R.;
Schønberg, S.A.;
Krokan, Hans Einar;
Bjerve, K.S..
(1998)
Effects of polyunsaturated fatty acids and their n-6 hydroperoxides on growth of five malignant cell lines and the significance of culture media.
Lipids
Academic article
-
Nilsen, H.;
Otterlei, Marit;
Haug, T.;
Solum, K.;
Nagelhus, T.A;
Skorpen, Frank.
(1997)
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.
Nucleic Acids Research (NAR)
Academic article
-
Nagelhus, T.;
Haug, T.;
Singh, K.K.;
Keshav, K.F.;
Skorpen, Frank;
Bharati, S..
(1997)
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit o replication protein A.
Journal of Biological Chemistry
Academic article
-
Schønberg, S.M.;
Rudra, P.K.;
Nøding, R.;
Bjerve, K.S;
Krokan, Hans Einar.
(1997)
Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids.
Carcinogenesis
Academic article
-
Schønberg, Svanhild A.;
Rudra, Parveen K.;
Nøding, Randi;
Skorpen, Frank;
Bjerve, Kristian S;
Krokan, Hans Einar.
(1997)
Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids.
Carcinogenesis
Academic article
-
Krokan, Hans Einar;
Standal, Rune;
Slupphaug, Geir.
(1997)
DNA glycosylase in the base excision repair of DNA.
Biochemical Journal
Academic article
-
Dizdaroglu, M.;
Karakaya, A.;
Jaruga, P.;
Slupphaug, Geir;
Krokan, Hans Einar.
(1996)
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage.
Nucleic Acids Research (NAR)
Academic article
-
Slupphaug, Geir;
Kavli, B.;
Mol, C.D.;
Arvai, A.;
Krokan, Hans Einar;
Tainer, J.A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Kavli, B.;
Slupphaug, Geir;
Mol, C.D.;
Arvai, A.S.;
Petersen, S.B.;
Tainer, J.A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Kavli, Bodil;
Slupphaug, Geir;
Mol, Clifford D.;
Arvai, Andrew S.;
Petersen, Steffen B.;
Tainer, John A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Haug, Terje;
Skorpen, Frank;
Kvaløy, Kirsti;
Eftedal, Ingrid;
Lund, Henning;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene : sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Genomics
Academic article
-
Lund, Henning;
Eftedal, Ingrid;
Haug, Terje;
Krokan, Hans Einar.
(1996)
Pseudogenes for the human uracil-DNA glycosylase on chromosomes 14 and 16.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Slupphaug, Geir;
Mol, Clifford D.;
Kavli, Bodil;
Arvai, Andrew S.;
Krokan, Hans Einar;
Tainer, John A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Dizdaroglu, Miral;
Karakaya, Asuman;
Jaruga, Pawel;
Slupphaug, Geir;
Krokan, Hans Einar.
(1996)
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage.
Nucleic Acids Research (NAR)
Academic article
-
Lehmann, A.R.;
Bridges, B.A.;
Hanawalt, P.C.;
Johnson, R.T.;
Kanaar, R.;
Krokan, Hans E..
(1996)
Workshop on processing of DNA damage.
Mutation research
Academic article
-
Lund, H.;
Eftedal, I.;
Haug, T.;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Nagelhus, T.;
Slupphaug, Geir;
Krokan, Hans Einar;
Lindmo, T..
(1996)
Fading correction for fluorescence quantitation in confocal microscopy.
Cytometry
Academic article
-
Haug, T.;
Skorpen, Frank;
Lund, H.;
Eftedal, I.;
Kvaløy, K.;
Krokan, Hans Einar.
(1996)
Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Genomics, Society and Policy
Academic article
-
Slupphaug, Geir;
Eftedal, Ingrid;
Kavli, Bodil;
Bharati, Sangeeta;
Helle, Nils M;
Haug, Terje.
(1995)
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase.
Biochemistry
Academic article
-
Nilsen, Hilde;
Yazdankhah, Siamak Pour;
Eftedal, Ingrid;
Krokan, Hans Einar.
(1995)
Sequence specificity for removal of uracil from U.A pairs and U.G mismatches by uracil-DNA glycosylase from Escherichia coli, and correlation with mutational hotspots.
FEBS Letters
Academic article
-
Slupphaug, Geir;
Alseth, Ingrun;
Eftedal, Ingrid;
Volden, Gunnar;
Krokan, Hans Einar.
(1993)
Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplification.
Analytical Biochemistry
Academic article
-
Slupphaug, G.;
Markussen, F.-H.;
Olsen, Lisbeth Charlotte;
Aasland, Rein;
Aarsæther, Niels;
Bakke, O..
(1993)
Human Uracil-DNA glycosylase is shared by the nucleus and the mitochondria.
Nucleic Acid Res
Academic article
-
Eftedal, Ingrid;
Guddal, Per Henrik;
Slupphaug, Geir;
Volden, Gunnar;
Krokan, Hans Einar.
(1993)
Consensus sequences for good and poor removal of uracil from double stranded DNA by uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Krokan, Hans Einar;
Bjerve, Kristian S;
Mørk, E..
(1993)
The enteral bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro.
Biochimica et Biophysica Acta
Academic article
-
Krokan, Hans Einar.
(1992)
Expression of O(6)-methylguanine - DNA methyltransferase and uracilDNA lycosylase in human placentae from smokers and non-smokers.
Carcinogenesis
Academic article
-
Olsen, Lisbeth Charlotte;
Aasland, Rein;
Krokan, H. E.;
Helland, Dag Emil.
(1992)
Human uracil DNA glycosylase cDNA complements E.coli ung mutants.
Nucleic Acid Res
Academic article
-
Slupphaug, G.;
Olsen, Lisbeth Charlotte;
Helland, Dag Emil;
Aasland, Rein;
Krokan, H. E..
(1991)
Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil- DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Aasland, Rein;
Olsen, Lisbeth Charlotte;
Spurr, N. K.;
Krokan, H. E.;
Helland, Dag Emil.
(1990)
Chromosomal assignment of Human Uracil-DNA Glycosylase to Chromosome 12.
Genomics
Academic article
-
Wist, Erik;
Krokan, Hans E..
(1978)
Preservation by glycerol of DNA synthetic capacity of isolated HeLa cell nuclei during long term storage at low temperature.
Experimental Cell Research
Academic article
-
Wist, Erik;
Undhjem, O;
Krokan, Hans E..
(1978)
Accumulation of small fragments of DNA in isolated HeLa cell nuclei due to transient incorporation of dUMP.
Biochimica et Biophysica Acta
Academic article
-
Krokan, Hans E.;
Wist, Erik;
Prydz, Hans Peter B.
(1977)
DNA replication intermediates in whole HeLa cells and isolated nuclei.
Biochimica et Biophysica Acta
Academic article
-
Krokan, Hans E.;
Wist, Erik;
Prydz, Hans Peter B.
(1977)
Effect of cytosol on DNA synthesis in isolated nuclei.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Wist, Erik;
Krokan, Hans E.;
Prydz, Hans Peter B.
(1976)
Effect of 1-beta-D-arabionsyl-cytosine-triphosphate on DNA synthesis in HeLa cell nuclei.
Biochemistry
Academic article
Books
-
Slupphaug, Geir;
Krokan, Hans Einar.
(2018)
Genomic Uracil - Evolution, Biology, Immunology and Disease.
World Scientific
World Scientific
Non-fiction book
-
Smeland, Erlend;
Prydz, Hans;
Ørstadvik, Karen Helene;
Frøland, Stig;
Aamdal, Steinar;
Myklebost, Ola.
(2000)
Genterapi Status og fremtidige muligheter innen klinisk medisin.
Lobo Grafisk AS
Non-fiction book
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bharati, S;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1998)
Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis.
DNA damage and repair: Oxygen Radical Effects, Cellular Prote ction and Biological Consequences.
Non-fiction book
-
Krokan, Hans Einar.
(1993)
Omega-3 fatty acids : metabolism and biological effects.
Advances in Life Sciences
Non-fiction book
-
Krokan, Hans Einar;
Valla, Svein;
Bones, Atle.
(1993)
Markørgener - sikkerhet for helse og miljø.
Direktoratet for naturforvaltning
Non-fiction book
Part of book/report
-
Kavli, Bodil Merete;
Slupphaug, Geir;
Krokan, Hans Einar.
(2020)
Genomic Uracil in Biology, Immunity and Cancer.
Royal Society of Chemistry (RSC) Publishing
Academic chapter/article/Conference paper
-
Slupphaug, Geir;
Krokan, Hans Einar.
(2018)
Genomic Uracil – Valuable Tool in Molecular Biology but Inherent Problem in Sequencing of Ancient DNA.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Viral Uracil - Uracil DNA glycosylases and dUTPases.
World Scientific
Chapter
-
Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2018)
Routes to Uracil in DNA.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
DNA Repair is Integrated with Many Cellular Processes.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Sarno, Antonio;
Slupphaug, Geir.
(2018)
Enzymology of Genomic Uracil Repair.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir;
Drabløs, Finn.
(2018)
The Earth, Life and Genomic Uracil.
World Scientific
Chapter
-
Krokan, Hans Einar;
Slupphaug, Geir;
Kavli, Bodil Merete.
(2017)
Genomic Uracil-Dangers and Benefits in processing.
Academic chapter/article/Conference paper
-
Larsen, Eivind La Puebla;
Randeberg, Lise Lyngsnes;
Gederaas, Odrun Arna;
Krokan, Hans Einar;
Hjelme, Dag Roar;
Svaasand, Lars O..
(2007)
In vitro study on methemoglobin formation in erythrocytes following hexyl-aminolevulinate induced photodynamic therapy.
SPIE - The International Society for Optics and Photonics
Academic chapter/article/Conference paper
-
Smeland, Erlend B;
Prydz, Hans Peter B;
Ørstavik, Karen Helene;
Frøland, Stig Sophus;
Aamdal, Steinar;
Myklebost, Ola.
(2000)
Genterapi. Status og fremtidige muligheter innen klinisk medisin.
Academic chapter/article/Conference paper
-
Krokan, Hans Einar.
(1999)
Kapittel 16: Vann og elektrolytter.
Cappelen Damm Høyskoleforlaget
Academic chapter/article/Conference paper
-
Krokan, Hans Einar;
Standal, Rune;
Bharati, Sangeeta;
Otterlei, Marit;
Haug, Terje;
Slupphaug, Geir.
(1997)
Uracil in DNA and the family of concerved uracil DNA glycosylases.
Academic chapter/article/Conference paper
Report
-
Helander, Linda;
Krokan, Hans Einar;
Gederaas, Odrun Arna;
Johnsson, Anders Carl G.;
Chen, Duan.
(2015)
Hexylaminolevulinate Photodynamic Treatment of Cancer Cell Lines. PhD Thesis.
Tapir Akademisk Forlag
Tapir Akademisk Forlag
Doctoral dissertation
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Overland, Hilde Bremseth;
Schønberg, Svanhild Margrethe Arentz;
Krokan, Hans Einar.
(2013)
ER stress, reactive oxygen species and autophagy in colon cancer cells treated with polyunsaturated marine fatty acids.
Doktoravhandlinger ved NTNU (1)
Doctoral dissertation
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Monsen, Vivi A Talstad;
Krokan, Hans Einar;
Aas, Per Arne.
(2010)
Mechanisms of alkylation damage repair by human AlkB homologues.
NTNU
Doctoral dissertation
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Krokan, Hans Einar;
Visnes, Torkild.
(2009)
DNA Excision repair of uracil and 5-fluorouracil in human cancer cell lines.
Det medisinske fakultet, NTNU
Doctoral dissertation
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Grøsvik, K;
Slupphaug, Geir;
Krokan, Hans Einar.
(2002)
"Characterisation of uracil-exising enzyme activities in organ extracts from UNG knockout and wild-type mice.".
NTNU
Thesis at a second degree level
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Nygård, M;
Nilsen, M;
Remseth, V;
Slupphaug, Geir;
Krokan, Hans Einar.
(2002)
Uttrykk av det membran-modifiserende enzymet UDPDG i E.coli som funksjon av dyrkningsbetingelser og induksjon av DNA-skader.
[Mangler utgivernavn]
Thesis at a second degree level
Knowledge Transfer
2017
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PosterLundbæk, Marie Benner; Sarno, Antonio; Liabakk, Nina-Beate; Aas, Per Arne; Krokan, Hans Einar; Kavli, Bodil Merete. (2017) Mitochondrial uracil-DNA glycosylase UNG1 supports class switch recombination and genomic uracil processing in mouse B-cell. Keystone B-cells and T Follicular Helper cells: Controling Long-Lived Immunity , Whistler 2017-04-23 - 2017-04-27
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PosterAlsøe, Lene; Sarno, Antonio; Carracedo Huroz, Sergio; Domanska, Diana Ewa; Dingler, Felix; Lirussi, Lisa. (2017) Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1 . 6th EU-US Conference on Repair of endogenous DNA damage 2017-09-24 - 2017-09-28
2016
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Academic lectureKrokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan , Matsue 2016-11-13 - 2016-11-17
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Academic lectureKavli, Bodil Merete; Pettersen, Henrik Sahlin; Ericsson, Ida; Hu, Yi; Krokan, Hans Einar. (2016) AID og genomisk uracil; kilde til mutasjoner og utvikling av B-celle lymphom. Onkologisk forum Onkologisk forum 2016 , Scandic hotel- Lerkendal, Trondheim 2016-11-17 - 2016-11-18
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Academic lectureLundbæk, Marie Benner; Sarno, Antonio; Liabakk, Nina-Beate; Krokan, Hans Einar; Kavli, Bodil Merete. (2016) Mitochondrial UNG1 supports class switch recombination in mouse B-cells. 10th 3R Symposium Organzing Committee 10th 3R International Symposium , Matsue 2016-11-13 - 2016-11-17
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Academic lectureKrokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. Russian Academy of Sciences, Siberian branch 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology , Akademorodok, Novosibirsk 2016-08-29 - 2016-09-03
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Academic lectureNilsen, Hilde; Kroustallaki, Pinelopi; Alsøe, Lene; Huroz, Sergio C; Sarno, Antonio; Esbensen, Ying. (2016) Telomere maintenance defects in mice deficient in SMUG1 uracil-DNA glycosylase. 10th 3R International Symposium Organizing Committee 10th 3R International Symposium , Matsue 2016-11-13 - 2016-11-17
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Academic lectureSarno, Antonio; Alsøe, Lene; Carracedo, Sergio; Tekin, Nuriya Basdag; Gupta, Tanima Sen; Jobert, Laure. (2016) UNG and SMUG1 complement each other in DNA uracil excision and DNA 5-hydroxymethyluracil originates from 5-hydroxymethylcytosine deamination in mice. 10th 3R International Symposium Organizing Committee 10th 3R International Symposium , Matsue 2016-11-13 - 2016-11-17
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LectureKrokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Turkish Society of Toxicology. Eurotox 2016 , Sivilla 2016-09-04 -
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Academic lectureKrokan, Hans Einar; Kavli, Bodil Merete; Slupphaug, Geir. (2016) DNA Repair in diagnosis and therapy of cancer - opportunities and problems. NTNU 1st International NTNU Symposium on Clinical Biomarkers of Cancer , Trondheim 2016-06-16 - 2016-06-17
2015
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Academic lectureKrokan, Hans Einar. (2015) All the things U are. Uiniversitetet i Oslo Tomas Lindahl Conference on DNA Repair , Oslo 2015-06-17 - 2015-06-21
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LectureKrokan, Hans Einar. (2015) Nobelprisen i kjemi for 2015 til forskere innen DNA reparasjon . Gløshaugen Akademiske Klubb, NTNU Gløshaugen Akademiske Klubb , Trondheim 2015-12-03 -
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InterviewKrokan, Hans Einar. (2015) Denne har funne oppskrifta på langt liv. nrk.no nrk.no [Internet] 2015-01-06
2014
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PosterRasmussen, Erik; Vågbø, Cathrine Broberg; Dahl, John Arne; Münch, Daniel; Krokan, Hans Einar; Klungland, Arne. (2014) Epigenetically modified cytosines in the honey bee genome. The Ecology of Food Perception Unconventional Model Animals in Food & Health , Oslo 2014-03-20 - 2014-03-21
2013
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InterviewKrokan, Hans Einar. (2013) Milepælstudie avslører kreftmutasjoner. forskning.no forskning.no [Internet] 2013-08-18
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PosterFonseca, Davi de Miranda; Baar, Cecilie Christensen; Assefa, Netsanet Gizaw; Moe, Elin; Liabakk, Nina-Beate; Leiros, Hanna-Kirsti S.. (2013) Thermo-sensitive human UNG-mutants. The Structural Cell Biology of DNA Repair Machines effort XII Annual SBDR Program Project Workshop , Berkeley, CA 2013-04-11 - 2013-04-13
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PosterRasmussen, Erik; Vågbø, Cathrine Broberg; Dahl, John Arne; Münch, Daniel; Krokan, Hans Einar; Klungland, Arne. (2013) Presence of modified cytosines in the honey bee genome. Insect Nutritional Homeostasis , Bonn 2013-05-01 - 2013-05-04
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InterviewKrokan, Hans Einar. (2013) 4-tråda DNA funne i menneskeceller. NRK.no/viten NRK.no/viten [Internet] 2013-01-21
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PosterPena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Norwegian Biochemical Society Contact Meeting , Lillehammer 2013-01-31 - 2013-02-03
2012
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Academic lectureKrokan, Hans Einar. (2012) Genomic Uracil-A Potent Mutagen, But Normal Intermediate in Adaptive Immunity. University of Texas Southwestern Medical Center Pathology Seminar Series – Special Lecture , Dallas 2012-10-05 - 2012-10-06
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Academic lectureKrokan, Hans Einar. (2012) Uracil in DNA – Generation and Processing. L.H. Bergersen, V. A. Bohr, K W. Caldecott, A. et. al. 4th Genome Dynamics in Neuroscience, Genome Instability in Aging and Brain Disease 2012-09-19 - 2012-09-22
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Popular scientific lectureKrokan, Hans Einar. (2012) Hvordan klarer organismer å vedlikeholde arvematerialet?. Sør-Trøndelag fylkeskommune Nettverkssamling i biologi/kjemi Sør-Trøndelag Fylkeskommune , Trondheim 2012-11-01 - 2012-11-01
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Academic lectureKrokan, Hans Einar. (2012) Genomic uracil - general mutagen, but normal intermediate in adaptive immunity. European Environmental Mutagenesis Society 42nd EEMS Annual Conference , Warsaw 2012-09-16 - 2012-09-20
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Academic lectureKrokan, Hans Einar. (2012) Genomic uracil – Friend and foe. Gene Center - University of Munich Gene Center/SFB 646 Seminar Series , München 2012-10-29 - 2012-10-29
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PosterFonseca, Davi de Miranda; Moe, Elin; Liabakk, Nina-Beate; Baar, Cecilie Christensen; Skorpen, Frank; Krokan, Hans Einar. (2012) Thermo-sensitive mutants of UNG protein studied by structural experiments – Perspectives. The 3rd Erling Seeberg Symposium on DNA Repair , Trondheim and Ørland 2012-06-19 - 2012-06-24
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Academic lectureJohnson, Matthew P; Brennecke, Shaun P.; Iversen, Ann-Charlotte; East, C; Olsen, Guro Dalheim; Kent, J. (2012) Genome-wide association scans identify novel maternal susceptibility loci for preeclampsia. ISSHP The XVIII ISSHP World Congress , Geneva 2012-07-09 - 2012-07-12
2011
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Academic lectureMunyeshyaka, Aloys; Helander, Linda; Plaetzer, Kristjan; Krokan, Hans Einar; Gederaas, Odrun Arna. (2011) Comparison of light intensities Hexylaminolevulinate mediated photodynamic therapy. Noffof Årsmøte til Noffof , Radiumhospitalet, Oslo 2011-11-18 - 2011-11-18
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PosterMunyeshyaka, Aloys; Helander, Linda; Plaetzer, Kristjan; Krokan, Hans Einar; Gederaas, Odrun Arna. (2011) Hexylaminolevulinate mediated photodynamic therapy with blue light on five cancer cell lines- a cytotoxicity study. BioStruct BioStruct , Jægtvollen 2011-10-01 - 2011-10-04
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InterviewKrokan, Hans Einar. (2011) Intervju om HeLa cellene fra kreftpasienten Henrietta Lacks. NRK P3 NRK P3 [Radio] 2011-11-30
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Academic lectureKrokan, Hans Einar. (2011) Functions of different uracil-DNA glycosylases and importance of tight cell cycle regulation. Leiden University Medical Center Responses to DNA damage: from molecular mechanism to human disease , Egmond aan Zee 2011-04-03 - 2011-04-08
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Popular scientific lectureKrokan, Hans Einar. (2011) Idédugnad om Menneskekroppen: ”Flaks og uflaks med gener”. Universitetet i Oslo 200-års jubiléet for Universitetet i Oslo , Oslo, Blindern 2011-10-15 - 2011-10-15
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PosterBaglo, Yan; Sousa, Mirta; Slupphaug, Geir; Hagen, Lars; Håvåg, Sissel; Helander, Linda. (2011) Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways. University of Dublin Cancer Proteomics 2011, European Molecular Biology Organization , The Burlington Hotel, Dublin 2011-06-20 - 2011-06-23
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PosterPettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir. (2011) UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. UiO 4th EU-USA conference on DNA base damage and repair , Holmenkollen Park Hotell 2011-05-18 - 2011-05-22
2010
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Academic lectureKrokan, Hans Einar. (2010) DNA Repair and Cancer. European Association for Cancer Research 21st Meeting of the European Association for Cancer Research , Oslo 2010-06-26 - 2010-06-29
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Programme participationKrokan, Hans Einar. (2010) Intervju vedrørende mulig økt karsinogenisitet pga. økt opptak av PAH forbindelser. NRK, Schrødingers katt NRK, Schrødingers katt [TV] 2010-11-25
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Academic lectureKrokan, Hans Einar. (2010) DNA Repair Proteins in prevention and induction of mutations. European Environmental Mutagen Society Joint Meeting of European Environmental Mutagen Society (EEMS) and the Society for Free Radical Research (SFFR). , Oslo 2010-09-12 - 2010-09-18
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Programme participationKrokan, Hans Einar. (2010) Intervju om ”Syntetisk liv (etter publikasjon om syntetisk bakterie, Craig Venter), samt samtale om vår forskning på reparasjon av gener ved NTNU. NRK Trønder-radioen 21.05.2010 NRK Trønder-radioen 21.05.2010 [Radio] 2010-05-21
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Academic lectureGilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Müller, rebecca; Catterall, Tara C. (2010) Identification of a new and widespread and functionally important PCNA-binding motif. NTNU 6th Norwegian National Proteomics Meeting , trondheim 2010-12-09 - 2010-12-10
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Popular scientific lectureKrokan, Hans Einar. (2010) Hvordan vedlikeholder vi vårt arvemateriale?. Gløshaugen Akademiske Klubb Seminarserie , Trondheim 2010-11-18 - 2010-11-18
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Academic lectureMeza, Trine Johansen; Moen, Marivi N.; Vågbø, Cathrine B.; Ulleland, Marius; Krokan, Hans Einar; Arne, Klungland. (2010) The DNA dioxygenase AtALKBH2 protects Arabidopsis thaliana against methylation damage. 9th Norwegian Arabidopsis Meeting , Oslo 2010-11-11 - 2010-11-11
2009
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Programme participationKrokan, Hans Einar. (2009) TV program, NRK1, Schrødingers katt - Forskningspolitikk. NRK1 TV NRK1 TV [TV] 2009-01-22
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Academic lectureSlupphaug, Geir; Doseth, Berit; Kavli, Bodil Merete; Visnes, Torkild; Hagen, Lars; Torseth, Kathrin. (2009) Genomic uracil processing in mice and men. 2.nd Erling Seeberg symposium on DNA repair , Ålesund/Geiranger 2009-06-20 - 2009-06-25
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Academic lectureAas, Per Arne; Diaz, Javier Pena; Liabakk, Nina-Beate; Krokan, Hans Einar; Skorpen, Frank. (2009) Overexpression of transcription factor AP-2 stimulates the P(A) promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression. IKM Tirdagsforedrag-IKM , Medisinsk Teknisk Forskningssenter 2009-05-18 - 2009-05-18
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Academic lectureKrokan, Hans Einar. (2009) Genome wide association studies on gene variants predisposing to lung cancer. St. Olavs Hospital og NTNU Seminar i molekylærmedisin , Trondheim 2009-01-28 - 2009-01-28
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Academic lectureKrokan, Hans Einar. (2009) Mechanism and fidelity of processing of uracil in DNA. Integrated Project in DNA Repair (EU) International symposium: DNA Damage response and repair mechanisms , Heraklion, Crete, Greece 2009-04-20 - 2009-04-23
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Academic lectureGilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Westbye, Marianne; Sousa, Mirta; Müller, Rebekka. (2009) The human AlkB homologs 1,2 and 3, localisation and tentative functions. Rikshospitalet-Radiumhospitalet og Universitetet i Oslo 2nd Erling Seeberg Symposium on DNA Repair 2009-06-20 - 2009-06-25
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Academic lectureKrokan, Hans Einar. (2009) Genvarianter som predisponerer for lungekreft. NTNU Seminar i Molekylærmedisin, 28.01.2009, Trondheim; , Trondheim 2009-01-28 - 2009-01-28
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Academic lectureKrokan, Hans Einar. (2009) Genetic predisposition to lung cancer – common SNPs important cause. Det Norske Vitenskaps-Akademi Sigurd K. Thoresen Foundation Workshop - HUMAN GENOMIC VARIATION AND DISEASE , Oslo 2009-10-06 - 2009-10-06
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Academic lectureKrokan, Hans Einar. (2009) DNA-interacting proteins as molecular machines. NTNU 4th NTNU NanoLab User Meeting , Trondheim 2009-05-13 - 2009-05-13
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Academic lectureKrokan, Hans Einar. (2009) Nobelpriser i medisin og fysiologi og i kjemi 2009. NTVA Møte i NTVA , Trondheim 2009-11-10 - 2009-11-10
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Academic lectureKrokan, Hans Einar; Visnes, Torkild; Doseth, Berit; Akbari, Mansour; Otterlei, Marit; Kavli, Bodil Merete. (2009) Uracil in DNA and its processing. E. Dogliotti, H. Krokan, T. Stevnsner, S. Mitra, S.H. Wilson 3rd US-EU Conference- Repair of Endogenous Genome Damage , Moody Gardens Hotel, Galveston, Texas 2009-02-21 - 2009-02-25
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Academic lectureHelander, Linda; Plaetzer, Kristjan; Krammer, Barbara; Krokan, Hans Einar; Gederaas, Odrun Arna. (2009) Reactive oxygen species and cytotoxicity in rat bladder cancer cells (AY-27) after hexyl 5-aminolevulinate-induced photodynamic therapy. European Society for Photobiology 13th Congress od European Society for Photobiology , Wroclaw 2009-09-05 - 2009-09-10
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Academic lectureGederaas, Odrun Arna; Husebye, Harald; Hjelde, Astrid; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Helander, Linda. (2009) In vivo and in vitro detection of PpIX after treatment with hexyl 5-aminolevulinate and light. European platform for Photodynamic medicine european society for Photobiology , Wroclaw 2009-09-05 - 2009-09-10
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Academic lectureGederaas, Odrun Arna; Hjelde, Astrid; Randeberg, Lise Lyngsnes; Halaas, Øyvind; Høgset, Anders; Krokan, Hans Einar. (2009) Photochemical Internalisation (PCI). IKM, NTNU Prosjektmøte, NTNU , IKM, NTNU 2009-03-09 - 2009-03-09
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PosterPsonka-Antonczyk, Katarzyna Maria; Akbari, Mansour; Otterlei, Marit; Krokan, Hans Einar; Stokke, Bjørn Torger. (2009) Uracil-DNA glycosylase (UNG) interacting with mismatched DNA – a single molecule approach. European Biophysical Societies' Association European Biophysics Congress , Genoa 2009-07-11 - 2009-07-15
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PosterHenrik Sahlin, Pettersen; Visnes, Torkild; Vågbø, Cathrine Broberg; Kavli, Bodil Merete; Krokan, Hans Einar. (2009) Cytotoxicity of 5-fluorouracil is mainly due to RNA effects and thymidylate synthase inhibition, not excessive DNA repair. Rikshospitalet-Radiumhospitalet og Universitetet i Oslo 2nd Erling Seeberg Symposium on DNA Repair , Ålesund og Geiranger 2009-06-20 - 2009-06-25
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PosterTalstad, Vivi A; Sundheim, Ottar; Aas, Per Arne; Krokan, Hans Einar. (2009) Structural basis for substrate specificity of human AlkB homologues 2 and 3. International symposium: DNA Damage Response and Repair Mechanisms , Heraklion, Crete 2009-04-20 - 2009-04-23
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PosterHegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. Keystone Symposia MicroRNA and Cancer Conference , Keystone, Colorado 2009-06-10 - 2009-06-15
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PosterBruheim, Per; Sletta, Håvard; Klinkenberg, Geir; Ellingsen, Trond Erling; Krokan, Hans Einar; Otterlei, Marit. (2009) Systems biology and high resolution genome-wide phenotyping of yeast used for identification of cellular and molecular effects of DNA damaging agents. 3rd US-EU Workshop "Systems level understanding of DNA damage responses" , Egmond aan Zee 2009-03-30 - 2009-04-01
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Popular scientific lectureKrokan, Hans Einar. (2009) Hva kreves for å få professor kompetanse?. SOMA - Linjeforening for alle masterstudenter på DMF ved NTN Møte , Trondheim 2009-10-28 - 2009-10-28
2008
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Academic lectureGederaas, Odrun Arna; Hjelde, Astrid; Husebye, Harald; Helander, Linda; Sæterbø, Kristin Grendstad; Krokan, Hans Einar. (2008) Effects of hexyl 5-aminolevulinate and light in rat bladder cancer cells. Ruder Boskovic Institute, Zagreb, Croatia Photodiagnosis and Photodynamic therapy, EMMP, Dubrovnik , Dubrovnic 2008-03-24 - 2008-03-28
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Academic lectureHelander, Linda; Gederaas, Odrun Arna; Hjelde, Astrid; Johnsson, Anders; Krokan, Hans Einar; Melø, Thor Bernt. (2008) Effects of hexyl 5-aminolevulinate and light in rat bladder cancer cells. Noffof Årsmøte i NOFFOF, Norsk Forening for Fotobiologi og Fotomedisin, Blindern, Oslo, Norge , Blindern, Oslo 2008-11-07 - 2008-11-07
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Academic lectureBaas, Nils Andreas; Børresen-Dale, Anne-Lise; Krokan, Hans Einar; Levine, Arnold. (2008) Conference on systems biology and disease. Konferanse 2008-08-18 - 2008-08-19
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Academic lectureKrokan, Hans Einar. (2008) Genetic variability and lung cancer. Norsk Biokjemisk Selskap, UMB Seminar Norsk Biokjemisk Selskap , Ås 2008-12-11 - 2008-12-11
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Academic lectureKrokan, Hans Einar. (2008) Researcher initiative as creative force in shaping of university strategy - some personal experiences. Institutt for bioteknologi, NTNU Minisymposium on Microbial Biotechnology 2008-11-17 - 2008-11-17
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Academic lectureKrokan, Hans Einar. (2008) DNA Repair, genetic variability and human cancer. Onkologisk forum Onkologisk forum 2008 2008-12-19 - 2008-12-21
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Academic lectureKrokan, Hans Einar. (2008) DNA Repair and Human Disease. Den svenske patologiförening Patologiföreningens Vårmöte 22.-25. mai, , Uppsala 2008-05-22 - 2008-05-24
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Academic lectureKrokan, Hans Einar. (2008) DNA Repair population studies. Consortium EU Integrated Project DNA Damage Response and Repair Mechanisms Annual Meeting , Rotterdam 2008-04-16 - 2008-04-19
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Academic lectureKrokan, Hans Einar. (2008) Genetiske polymorfismer ved lungekreft - en multisenterstudie. HUNT Biobank Inforamsjonsmøte om biobankplattformen i FUGE , Trondheim 2008-06-05 - 2008-06-05
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Academic lectureKrokan, Hans Einar. (2008) Genome-wide scans for SNPs predisposing to cancer. Universitetet i Tromsø Seminar during "Tromsø Cancer Course" , Tromsø 2008-04-23 - 2008-04-23
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Academic lectureKrokan, Hans Einar. (2008) DNA Repair - from Structure to Population Studies and Human Disease. Danish Centre for Molecular Gerontology Aging - from molecules to population , Helsingør 2008-05-12 - 2008-05-14
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Academic lectureKrokan, Hans Einar. (2008) Uracil in DNA and its processing by different DNA glycosylases. Royal Society Royal Society Discussion Meeting , London 2008-06-09 - 2008-06-10
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Academic lectureSlupphaug, Geir; Westbye, Marianne P.; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi. (2008) Human ABH1 is a predominantly mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Ist Russian-EU meeting in Genomic maintenance , St. Petersburg 2008-06-24 - 2008-06-26
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InterviewSkorpen, Frank; Krokan, Hans Einar. (2008) NTNU-forskere fant lungekreftgen. Adresseavisen Adresseavisen [Newspaper] 2008-04-04
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PosterTalstad, Vivi A; Sundheim, Ottar; Aas, Per Arne; Krokan, Hans Einar. (2008) Identification of the motif that determines double strand substrate preference of hABH2 by domain swapping between hABH3 and hABH2. DNA Repair EU Integrated Project DNA repair annual meeting 2008 , Rotterdam 2008-04-16 - 2008-04-18
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PosterHelander, Linda; Gederaas, Odrun Arna; Hjelde, Astrid; Johnsson, Anders; Krokan, Hans Einar; Melø, Thor Bernt. (2008) Effects of hexyl 5-aminolevulinate and light in rat bladder cancer cells. 7th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice, Brixen/Bressanone, Italia , Bressanone/Brixen 2008-10-07 - 2008-10-11
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Popular scientific lectureKrokan, Hans Einar. (2008) Tale ved mottakelse av Kong Olav V. kreftforskningspris for 2008. Den Norske Kreftforening Utdeling av Kong Olav V. Kreftforskningspris for 2008 , Oslo 2008-06-11 - 2008-06-11
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Popular scientific lectureKrokan, Hans Einar. (2008) Utsikt fra elfenbenstårnet. FUGE Midt-Norge Juleseminar FUGE Midt-Norge , Trondheim 2008-12-09 - 2008-12-09
2007
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Academic lectureJakobsen, Caroline Hild; Bremseth, Hilde; Størvold, Gro Leite; Olsen, Karina Standahl; Follestad, Turid; Lundemo, Anne Gøril. (2007) DHA-induced growth inhibition of cancer cells is associated with disturbances in cholesterol metabolism, calcium homeostasis and induction of ER stress. Mikromatriseplattformen Foredrag i MOL8003 , Trondheim, NTNU 2007-03-27 - 2007-03-27
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Academic lectureGederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei. (2007) 5-ALA-based photodynamic therapy in an experimental bladder tumour model. Universitetet i Lund Forskningsseminar, Lunds Universitets Medisinska Lasercentrum , Lund 2007-02-20 - 2007-02-20
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Academic lectureGederaas, Odrun Arna; Randeberg, Lise Lyngsnes; Larsen, Eivind La Puebla; Hjelde, Astrid; Arum, Carl-Jørgen; Brunsvik, Anders. (2007) Effects of hexyl 5-aminolevulinate and light in a rat bladder cancer model. ESP 12 th Congress, European Society for Photobiology, Bath , Bath 2007-09-01 - 2007-09-06
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Academic lectureKrokan, Hans Einar. (2007) MØTE PÅ STIKLESTAD 937 ÅR ETTER. Institutt-dag, Stiklestad 2007-06-18 - 2007-06-18
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Academic lectureKrokan, Hans Einar. (2007) Review of selected topics from 3rd Japan - US DNA Repair Meeting, Akiu, Sendai, Japan, May 7-11, 2007. Laboratoriesenteret 2007-06-04 - 2007-06-04
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Academic lectureKrokan, Hans Einar. (2007) Tirsdagsmøte 16.januar 2007 "INSTITUTT FOR KREFTFORSKNING OG MOLEKYLÆR MEDISIN: Hva skal vi gjøre når vi blir stor?". Laboratoriesenteret 2007-01-16 - 2007-01-16
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Academic lectureVisnes, Torkild; Kavli, Bodil Merete; Pettersen, Henrik P Sahlin; Krokan, Hans Einar. (2007) Efficient repair of 5-fluorouracil from DNA by base excision repair: roles of UNG2 and SMUG1. EU EU - IP DNA Repair workshop for young scientists , Gent 2007-05-13 - 2007-05-16
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Academic lectureKrokan, Hans Einar. (2007) Repair of damaged bases by bases excision and direct repair. 3rd Japan - US DNA Repair Meeting , Akiu, Sendai 2007-05-07 - 2007-05-11
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Academic lectureKrokan, Hans Einar. (2007) Repair of base lesions in DNA - mechanisms and significance. Norsk Biokjemisk Selskap, Avdeling Oslo 2007-08-30 - 2007-08-30
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Academic lecture
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PosterJakobsen, Caroline Hild; Størvold, Gro Leite; Bremseth, Hilde; Krokan, Hans Einar; Schønberg, Svanhild Margrethe Arentz. (2007) DHA induces ER stress, cell cycle arrest and disturbance in cholesterol homeostasis in colon cancer cells. Cell Stress Society Internatinal WORLD CONFERENCE OF STRESS , Budapest 2007-08-23 - 2007-08-26
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PosterKrokan, Hans Einar. (2007) DNA REPAIR MECHANISMS AND HUMAN DISEASE. Universitetet i Tromsø Institutt for medisinsk biologi 2007-04-25 - 2007-04-25
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PosterBremseth, Hilde; Jakobsen, Caroline Hild; Lundemo, Anne Gøril; Størvold, Gro Leite; Krokan, Hans Einar; Schønberg, Svanhild Margrethe Arentz. (2007) Stress protein activation by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. International cell stress society 2nd World conference of stress , Budapest 2007-08-23 - 2007-08-26
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PosterLarsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Krokan, Hans Einar; Hjelme, Dag Roar; Svaasand, Lars O.. (2007) In vitro study on methemoglobin formation in erythrocytes following hexyl-aminolevulinate induced photodynamic therapy. SPIE SPIE Photonics West 2007: Biomedical Optics (BiOS) , San Jose 2007-01-20 - 2007-01-25
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Popular scientific lectureKrokan, Hans Einar. (2007) DNA Reparasjon og genomikk i helse og sykdom. Eldre legers klubb Faglig møte , Trondheim 2007-12-06 - 2007-12-06
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Popular scientific lectureKrokan, Hans Einar. (2007) "Utfordringer sett fra instituttleders ståsted". Ledermøte ved Det medisinske fakultet , Baardshaug, Orkanger 2007-09-26 - 2007-09-26
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PosterHjelde, Astrid; Gederaas, Odrun Arna; Krokan, Hans Einar; Brubakk, Alf O. (2007) The effects of increasing oxygen concentrations in PDT on cell survival and lipid peroxidation in different cancer cell lines. 12th Congress of the European Society for Photobiology , Bath 2007-09-01 - 2007-09-06
2006
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Academic lectureGederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Arum, Carl-Jørgen; Brunsvik, Anders; Hjelde, Astrid. (2006) In vivo and in vitro detection of PpIX after treatment with hexyl 5-aminolevulinate and light in a rat bladder cancer model. University of Buenos Aires 5th international workshop on photodynamic theraphy and photodetection with porphyrin precursors , Buenos Aires 2006-06-22 -
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Academic lectureLarsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Krokan, Hans Einar; Hjelme, Dag Roar. (2006) Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy. American Society for Laser Medicine and Surgery Twenty-Sixth Annual Meeting , Boston, Massachusetts 2006-04-05 - 2006-04-09
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Academic lectureKrokan, Hans Einar. (2006) Functions of uracil-DNA glycosylase in B-cells: Cells, mice and man. EU Integrated Project on DNA Repair Introductory Course for Young Scientists , Noordwijkerhout 2006-04-01 - 2006-04-01
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Academic lectureKrokan, Hans Einar. (2006) Uracil in DNA - Impact and Repair. Center of Molecular Biology and Neuroscience First Genome Dynamics in Neuroscience Meeting , Oslo 2006-04-27 - 2006-04-29
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Academic lectureKrokan, Hans Einar. (2006) Base excision repair proteins in cancer prevention and acquired immune responses. Federation of European Biochemical Society 31st FEBS Congress , Istanbul 2006-06-24 - 2006-06-29
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Academic lectureKrokan, Hans Einar. (2006) DNA Repair Proteins and Acquired Immunity. European Mutagenesis Society European Mutagenesis Society Meeting , Prague 2006-07-02 - 2006-07-06
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Academic lectureKrokan, Hans Einar. (2006) Comments on the history of DNA repair and molecular biology in Norway. UiO og NTNU 1st international Erling Seeberg Conference , Bodø/Henningsvær 2006-05-28 - 2006-06-02
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Academic lectureKrokan, Hans Einar. (2006) BER and direct repair - uracil and methylations. EU Integrated Project on DNA Repair DNA Repair: from Molecular Mechanism to Human Disease , Noordwijkerhout 2006-04-02 - 2006-04-07
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Academic lectureGederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Arum, Carl-Jørgen; Brunsvik, Anders; Hjelde, Astrid. (2006) In vivo and in vitro detection of PpIX after treatment with 5-aminolevulinate and light. University of Padova 6th International symposium on photodynamic diagnosis and therapy in clinical practice , Brixen 2006-10-10 - 2006-10-14
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PosterHagen, Lars; Kavli, Bodil Merete; Sundheim, Ottar; Sousa, Mirta; Otterlei, Marit; Liabakk, Nina-Beate. (2006) Regulation of uracil base excision repair by post-translational modifications. Erling Seeberg Symposium on DNA Repair 2006-05-28 - 2006-06-02
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Talstad, Vivi; Aas, Per Arne. (2006) Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. Erling Seeberg Symposium on DNA Repair 2006-05-28 - 2006-06-02
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PosterVågbø, Cathrine Broberg; Talstad, Vivi; Aas, Per Arne; Krokan, Hans Einar. (2006) The in vivo role of mABH2 and mABH3 assessed through a highly sensitive and specific LC-MS/MS method for quantifying methyl lesions in DNA. EU Integrated Project “DNA Damage Response and Rep. Mech." DNA Repair: from Molecular Mechanism to Human Disease , Noordwijkerhout 2006-04-02 - 2006-04-07
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Aas, Per Arne; Drabløs, Finn. (2006) Crystal structure of hABH3 DNA/RNA demethylase reveals a novel active-site leucine oxidation. Norwegian Biochemical Society (NBS) The Norwegian Biochemical Society 42. Contact Meeting , Storefjell, Storefjell Hotell 2006-01-19 - 2006-01-22
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PosterHanssen-Bauer, Audun; Solvang-Garten, Karin; Akbari, Mansour; Krokan, Hans Einar; Otterlei, Marit. (2006) Functional analysis of XRCC1 associated repair complexes containing the XRCC1 polymorphisms Arg194Trp, Arg280His, and Arg399Gln. EU IP "DNA Damage Response and Repair Mechanisms" DNA repair: from Molecular Mechanism to Human Disease , Noordwijkerhout 2006-04-02 - 2006-04-07
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PosterVågbø, Cathrine Broberg; Talstad, Vivi; Aas, Per Arne; Krokan, Hans Einar. (2006) The in vivo role of mABH2 and mABH3 assessed through a highly sensitive and specific LC-MS/MS method for quantifying methyl lesions in DNA. Universitet i Oslo Erling Seeberg Symposium on DNA repair , Henningsvær, Lofoten 2006-05-28 - 2006-06-02
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Popular scientific lectureKrokan, Hans Einar. (2006) Hvordan virker genene våre?. NTNU Lørdagsuniversitetet, NTNU , Suhm-huset, Trondheim 2006-09-30 - 2006-09-30
2005
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Academic lectureGederaas, Odrun Arna; Schønberg, Svanhild Margrethe Arentz; Ramstad, Ståle; Berg, Kristian; Johnsson, Anders Carl G.; Krokan, Hans Einar. (2005) Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization. International Congress in Photobiology , Aix-les-Bains 2005-09-03 - 2005-09-08
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Aas, Per Arne; Drabløs, Finn. (2005) Structure of the hABH3 DNA demethylase implicates an oxidized leucine residue in catalysis. 2nd ESF Functional Genomics and disease 2005-09-06 -
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PosterDiaz, Javier Pena; Hegre, Siv Anita; Akbari, Mansour; Sousa, Mirta; Sundheim, Ottar; Hanssen-Bauer, Audun. (2005) Recruitment of the chaperone Hsp70 to Base Excision Repair complexes. 2nd EU-US DNA RepairMeeting 2005-11-29 - 2005-12-03
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PosterKavli, Bodil Merete; Diaz, Javier Pena; Otterlei, Marit; Liabakk, Nina-Beate; Giljam, Karin Margaretha; Krokan, Hans Einar. (2005) The enzymatic activity of human uracil-DNA glycosylase UNG2 is regulated by N-terminal phosphorylation during cell cycle. Instituto Superiore di Sanita/EMBO 2nd EU-US DNA Repair Meeting: Endogeneous Stress, Base excision repair and related processes , Erice, Sicily 2005-11-28 - 2005-12-03
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PosterGederaas, Odrun Arna; Schønberg, Svanhild Margrethe Arentz; Ramstad, Ståle; Berg, Kristian; Johnsson, Anders Carl G.; Krokan, Hans Einar. (2005) Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization. International World Congress , Munchen 2005-06-21 - 2005-06-24
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PosterOtterlei, Marit; Akbari, Mansour; Hanssen-Bauer, Audun; Garten, Karin; Wilson III, David; Andersen, Sonja Benedikte. (2005) Base Excision Repair and Single Strand Break Repair proficient XRCC1 complexes. DNA repair meeting , Sicily 2005-11-28 - 2005-12-03
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Academic lectureSchønberg, Svanhild Margrethe; Follestad, Turid; Krokan, Hans Einar; Bremseth, Hilde; Lundemo, Anne Gøril; Jakobsen, Caroline Hild. (2005) Endoplasmic reticulum stress induced by DHA leads to growth arrest of human colon cancer cells. ICBL 46th International Conference on the Bioscience of Lipids , Ajaccio, Corsica 2005-09-20 - 2005-09-24
2004
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PosterSundheim, Ottar; Parikh, Sudip S; Lund, Terje; Krokan, Hans Einar; Slupphaug, Geir; Tainer, John A. (2004) Structural and biochemical analysis of the minor-groove recognition loop (MGRL) motif in UDG. American Society for Microbiology DNA repair and mutagenesis: From molecular structure to biological consequences , Southampton 2004-11-14 - 2004-11-20
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Academic lectureGederaas, Odrun Arna; Schønberg, S; Ramstad, S.; Johnsson, Anders Carl G.; Krokan, Hans Einar. (2004) Effects of Polyunsaturated Fatty Acids on 5-Aminolevulinic Acid based Photosensitisation in four different human cancer cell lines. Photodynamic therapy and clinical medicine. International workshop , Trondheim 2004-11-11 -
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Academic lectureKrokan, Hans Einar. (2004) Molecular and functional interactions in macromolecular repair. 29th meeting of the federation of the European Biochemical Societies , Warsaw 2004-06-26 - 2004-07-01
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Academic lectureKrokan, Hans Einar. (2004) Repair as part of a complex cellular defence system. Domus medicus Jahre forelesning , Oslo 2004-10-08 -
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Academic lectureHjelde, Astrid; Gederaas, Odrun Arna; Krokan, Hans Einar; Brubakk, Alf O. (2004) The effect of hyperoxia in photodynamic therapy in 3 different cell lines. EUBS 2004 , Ajaccio 2004-09-15 - 2004-09-19
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PosterKavli, Bodil; Otterlei, Marit; Liabakk, Nina-Beate; Krokan, Hans Einar; Slupphaug, Geir. (2004) The mutant UNG2-F-25 1S associated with HIGM syndrome is abnormally translocated and degraded, and results in impaired nuclear uracil excision and accumulation of genomic uracil. ASM Conference on DNA Repair and Mutagenesis , Bermuda 2004-11-14 - 2004-11-20
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PosterSundheim, Ottar; Krokan, Hans Einar; Slupphaug, Geir. (2004) Structural anc biochemical analysis of the major groove recognition loop (MGRL). Gordon Conference on Mutagenesis , Oxford, England 2004-09-12 - 2004-09-17
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PosterAkbari, Mansour; Monterotti, Bruno; Krokan, Hans Einar; Otterlei, Marit. (2004) XRCC1-Associated repair complexes (ARC). DNA-repair and mutagenesis: From molecular structure to biological consequences 2004-11-14 - 2004-11-20
2003
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Academic lectureKrokan, Hans Einar. (2003) Novel aspects of macromolecular repair and interactions with the immune system. Danich Center for Molecular Gerontology , Aarhus 2003-10-28 -
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Academic lectureGederaas, Odrun; Schønberg, Svanhild; Ramstad, Ståle; Johnsson, Anders Carl G.; Krokan, Hans Einar. (2003) Effects of Polyunsaturated Fatty Acids on 5-Aminolevulinic Acid based Photosensitisation in four Different Human Cancer Cell Lines. ESP 2003, 10th Congress of the European Society for Photobiology. , General Hospital Vienna, Austria 2003-09-11 -
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Academic lectureKrokan, Hans Einar. (2003) "DNA-dobbeltspiralen i 50 år". Foredrag i Det Kongelig Norske Videnskapers Selskap , Oslo 2003-12-15 -
2002
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Interview
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Interview
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Interview
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Interview
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Interview
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Interview
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InterviewSundan, Anders; Otterlei, Marit; Krokan, Hans Einar. (2002) Det gode liv på Øya: Rapport fra et vinnermiljø. [Newspaper] 2002-06-13
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PosterAndersen, Sonja; Nilsen, Hilde; Grøsvik, K; Kønig, I; Sneve, R; Slupphaug, Geir. (2002) "URACIL-DNAGLYCOSYLASE KNOCKOUT MICE-effects on lifespan and health. Characterisation of uracil removing activities in wild type and Ung deficient mice.". Meeting on DNA repair , Warsaw 2002-09-07 -
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Academic lectureKrokan, Hans Einar. (2002) Genteknologi-betydning og trender. Foredrag i Den Norske Lægeforening , Oslo 2002-12-17 -
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Academic lectureKrokan, Hans Einar. (2002) Molecular and Cellular Mechanisms of Carcinogenesis and Cancer Chemotherapy. 9th International Charles Heidelberger Symphosium , Bergen 2002-07-08 -
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Academic lectureKrokan, Hans Einar. (2002) Union International Contre Cancer (UICC). Union International Contre Cancer , Oslo 2002-07-05 -
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Academic lectureSchønberg, Svanhild; Nilsen, Asbjørn; Gederaas, Odrun; Lundemo, Anne Gøril; Talstad, Vivi; Krokan, Hans Einar. (2002) Effects of polyunsaturated fatty acids on human tumor cell growth. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
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Academic lectureAas, Per Arne; Otterlei, Marit; Skorpen, Frank; Akbari, Mansour; Slupphaug, Geir; Krokan, Hans Einar. (2002) Repair of alkylated single-stranded DNA and RNA in living cells. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
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Academic lectureKrokan, Hans Einar. (2002) "DNA Damage and Repair-Fundamental Aspects and Contribution to Human Disorders.". 32nd Annual Meeting of the European Environmental Mutagen Society. , Warsaw 2002-09-10 -
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Academic lectureKrokan, Hans Einar. (2002) "Receptor-Ligand Interactions. Molecular, Physiological and Pharmacological Aspects.". 7th IUBMB Conference , Bergen 2002-05-08 -
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Academic lectureKrokan, Hans Einar. (2002) Repair of uracil in DNA requires many different uracil-DNA glycosylases. 28th Meeting of the Federation of European Biochemical Sosieties , Istanbul, Turkey 2002-10-25 -
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Academic lectureBirkeland, O.R; Fjeldstad, S.H; Humberset, H; Nedland, M; Snøve, O; Svingen, B. (2002) A new method for unbiased and automatic data analysis and hypothesis generation. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
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PosterKavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Aas, Per Arne; Otterlei, Marit; Skorpen, Frank. (2002) Biochemical and kinetic analysis of human UNG2 and SMUG1 indicate overlapping functions in DNA-uracil repair in the nucleus. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life , Quality Hotel Røros 2002-01-20 -
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PosterAndersen, Sonja; Nilsen, Hilde; Grøsvik, K; Kønig, I; Sneve, R; Slupphaug, Geir. (2002) Uracil-DNA glycosylase knockout mice. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life , Røros, Norge 2002-01-20 -
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PosterHolthe, Margareth; Rakvåg, Trude Teoline; Klepstad, Pål; Borchgrevink, Petter Chr.; Zahlsen, Kolbjørn; Dale, Ola. (2002) UGT2B7 and u-opioid receptor (OPRM) gene variants: implikacations for morphine metabolism and analgesia in cancer patients. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
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PosterKavli, Bodil; Otterlei, Marit; Sundheim, Ottar; Akbari, Mansour; Aas, Per Arne; Krokan, Hans Einar. (2002) Biochemical and kinetic analysis of human UNG2 and SMUG1 indicate overlapping functions in uracil-DNA repair in the nucleus. Mutagenesis and Carcinogenesis, Gordon Research Conference , Ventura, California, USA 2002-03-08 -
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PosterVisnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar. (2002) To BER or not to BER - is that the question?. Norsk Biokjemisk Selskaps Vintermøte , Røros, Norge 2002-01-20 -
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PosterPena-Diaz, Javier; Farez-Vidal, M.E; Sundheim, Ottar; Leal-Cortijo, I; Gonzales-Pacanowska, D; Krokan, Hans Einar. (2002) Kinetic characterisation of the uracil-DNA glycosylase from the protozoa parasite Trypanosome cruziNorsk biokjemis. 38. Biokjemiske kontaktmøte , Røros, Norge 2002-01-20 -
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PosterVisnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar. (2002) The signifisance of variation of uracil DNA.glycosylase activity on uracil initiated base exicion repair. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life , Quality Hotel Røros 2002-01-20 -
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PosterLauritzen, K.H; Aas, Per Arne; Krokan, Hans Einar; Skorpen, Frank. (2002) The human mitochondrial uracil-DNA glycosylase (UNG1) promoter is induced by high levels of CO2. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
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PosterKavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Aas, Per Arne. (2002) Substrate preference and enzyme kinetics reveal distinct properties of UNG2 and SMUG1 in cellular base-excision repair; hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches and U in single stranded DNA, with hSMUG1 as a broad specificity backup. 32nd Annual Meeting of European Environmental Mutagen Society. DNA Damage and Repair Fundamental Aspects and Contribution to Human Disorders , Warsaw. Poland 2002-09-07 -
2001
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Interview
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PosterNilsen, H.; Robins, P; Haushalters, K.; Krokan, Hans Einar; Verdine, G.; Barnes, D.. (2001) Base excision repair of uracil in mammalian cells. Workshop DNA repair: interplay with other cellular processes. , Noordwijkerhout, The Netherlands, February 25 - March 2, 2001
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PosterHolte, Monica; Klepstad, Pål; Borchgrevink, Petter Chr.; Kaasa, Stein; Idle, Jeffrey; Krokan, Hans Einar. (2001) The Significance of the UGT 2B7 HIS268TYR Polymorphism in the formation of morphine 3-glucoronide and morphine 6-glucuronide from morphine in human. 32nd International Narcotics Research Conferanse , Helsinki, Finland 2001-07-19 -
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PosterSchønberg, Svanhild; Gederaas, Odrun; Nilsen, Asbjørn; Lundemo, Anne Gøril; Talstad, Vivi; Krokan, Hans Einar. (2001) Effects of polyunsaturated fatty acids on human tumor cell growth. Lipidkongress, Bergen , Bergen 2001-06-08 -
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PosterSundheim, Ottar; Otterlei, Marit; Kavli, Bodil; Skorpen, Frank; Aas, Per Arne; Krokan, Hans Einar. (2001) Structure-function analysis of the human uracil-DNA glycosylase hSMUG1. Sixth International School on the Crystallography of Biological Macromolecules. , Como, Italy 2001-05-17 -
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PosterSlupphaug, Geir; Skorpen, Frank; Nilsen, H.; Fenstad, M.; Rosello, Ch.; Otterlei, Marit. (2001) Functional implications of the UNG2 regulatory domain in BER and transcription regulation. Workshop DNA repair: Interplay with other cellular processes , Noordwijkerhout, The Netherlands, February 25 - March 2, 2001
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Academic lectureKrokan, Hans Einar. (2001) Ved inngangen til biologiens århundre. Bioteknologi i framtiden. Seminar arrangert av NTVA , Lerchendal gård, Trondheim, 27. mars 2001
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Academic lectureKrokan, Hans Einar. (2001) Summary of a poster session on Base Excision repair. Workshop: DNA Repair: Interplay with other cellular processes. , Nederland 2001-03-25 -
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Academic lectureKrokan, Hans Einar. (2001) Basal kreftforskning - DNA-skader, reparasjon og evolusjon. AstraZeneca , Tanumstrand Hotel, Sverige 2001-07-31 -
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Academic lectureKrokan, Hans Einar. (2001) Damage and repair of DNA in mammalian cells-emphasis on repair of DNA breaks. Norwegian Academy of Science and Letters, Geomedical commitee. , Oslo 2001-06-05 -
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Academic lectureKrokan, Hans Einar. (2001) Basal kreftforskning - hvilke gener er endret i kreftceller?. AstraZeneca, Norge , Tanumstrand Hotel, Sverige 2001-07-31 -
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Academic lectureKrokan, Hans Einar. (2001) Aktuelle problemstillinger i molekylærbiologi. Rit , Trondheim 2001-05-10 -
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Academic lectureKrokan, Hans Einar. (2001) Mammalian Base Excicion repair. Department of Molecular Genetics, Institute of Development, Aging and Cancer, Tohoku University , Sendai, Japan 2001-11-09 -
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Academic lectureKrokan, Hans Einar. (2001) The molecular anatomy of base excision repair. New Members Workshop II (EMBO) "Frontiers of Molecular Biology" , Heraklion, Greece 2001-10-16 -
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Academic lecture
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Academic lectureKrokan, Hans Einar. (2001) Mammalian DNA repair and damage tolerance. Biomedical Center , University of Uppsala, Sverige 2001-12-18 -
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Academic lectureKrokan, Hans Einar. (2001) Kultur, vitenskap og det humane genom - variasjon over ett tema. Toppforskningsprogrammet i Norges Forskningsråd , Hemsedal 2001-09-23 -
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Academic lectureKrokan, Hans Einar. (2001) DNA repair mechanisms. Nordic Society for Pediatric and Hematologic Oncology, , Trondheim 2001-05-06 -
2000
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Programme participation
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Popular scientific lectureParikh, Sudip S; Walcher, Gunter; Jones, Garry D; Slupphaug, Geir; Krokan, Hans Einar; Tainer, John A. (2000) UDG-DNA Uncleaved-Substrate Structure is Strained by Coupled Stereoelectronic Effects. DNA Base Excision Repair Workshop (BER 2000 Workshop) , Galveston, Texas, USA
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Popular scientific lectureKrokan, Hans Einar. (2000) Structure-Function Aspects of Human Uracil-DNA Glycosylase and its Interactions with Other Proteins. DNA Base Excisiojn Repair Workshop (BER 2000 WORKSHOP) , San Luis Resort and Conference Center, Galveston, Texas, USA
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Popular scientific lectureNilsen, Hilde; Roswell, Ian; Robins, Peter; Slupphaug, Geir; Steinsbekk, Kristin; Otterlei, Marit. (2000) Characterisation Of The Major Murine Uracil-DNA Glycosylase And Expression Patterns And Generation of ung/-Knockout Mice. DNA Base Excision Repair Workshop (BER 2000 Workshop) , Galveston, Texas, USA March 10 - 13, 2000
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Popular scientific lectureKrokan, Hans Einar; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank; Andersen, Sonja. (2000) Structure-function aspects of human uracil-DNA glycosylase and its interactions with other proteins. DNA Base Excision Repair Workshop (BER 2000 WORKSHOP) , Galveston, Texas, March 10 - 13, 2000
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Popular scientific lectureKrokan, Hans Einar. (2000) Mammalian uracil-DNA glycosylase. Oppdalsmøte 2000 , Oppdal, 4. og 5. april 2000
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Academic lectureKrokan, Hans Einar. (2000) Molecular anatomy and physiology of the DNA repair enzyme uracil-DNA glycosylase. 18th International Congress of Biochemistry and Molecular Biology Beyond Genome , Cambridge
1999
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Popular scientific lecture
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Popular scientific lectureNilsen, Hilde; Barnes, D.E.; Lindahl, T.; Krokan, Hans Einar. (1999) Mouse model deficient in uracil-DNA glycosylase encoded by the Ung gene: effects on spontaneous mutation frequency. The 8th Jerusalem Spring School in Life Sciences on DNA Repair and Human Disease , The Hebrew University, Jerusalem, Israel May 2-7, 1999
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PosterKrokan, Hans Einar; Slupphaug, Geir; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank. (1999) Excicion Repar of DNA Damage 1. , 1-7 november 1999
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PosterOtterlei, Marit; Kavli, B.; Standal, R.; Skjelbred, Camilla; Bharati, S.; Krokan, Hans Einar. (1999) In vivo Repair of AP-sites in the E.coli Chromosome. , 1-7 november 1999
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PosterBarikh, S.S.; Lund, T.; Slupphaug, Geir; Krokan, Hans Einar; Ghazal, P.; Tainer, J.A.. (1999) Structural and biochemical analysis of a cytomegalovirus-human UDG chimera created by functional segment exchange. , 1-7 november 1999
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PosterBarnes, D.E.; Klungland, A.; Nilsen, Hilde; Morita, M.; Epe, B.; Krokan, Hans Einar. (1999) Excision Repair of DNA Damage 11. , 1-7 november 1999
1998
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Academic lectureBharati, Sangeeta; Krokan, Hans Einar; Kristiansen, Lena; Otterlei, Marit; Slupphaug, Geir. (1998) Human mitochondrial uracil-DNA glycosylase preform (UNG1)is processed to two forms one of which is resistant to inhibition by AP-sites. AACR Special Conference in Cancer Research. Endogeneous sources of Mutations. , Ft. Myers, Florida
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PosterKrokan, Hans Einar. (1998) Human uracil-DNA glycosylase: Gene structure, regulation and structural basis for enzyme catalysis. FEBS Silver Jubilee Meeting , Copenhagen, Denmark
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PosterKrokan, Hans Einar. (1998) DNA REPAIR AND CANCER. Clinical Implications and Molecular Epidemiology of Human Lung Cancer , Oslo
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PosterKavli, Bodil; Otterlei, Marit; Skjelbred, Camilla; Standal, Rune; Bharati, Sangeeta; Krokan, Hans Einar. (1998) Mutation frequency and mutation spectra caused by chromosomal AP-site in repair deficient E.coli strains. Norsk Biokjemisk Selskaps møte , Lillehammer
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PosterHaug, Terje; Aas, Per Arne; Skorpen, Frank; Malm, Veslemøy; Skjelbred, Camilla; Krokan, Hans Einar. (1998) Regulation of expression of nuclear and mitocondrialforms of human uracil-DNA glycosylase. Norsk Biokjmisk Vintermøte , Lillehammer
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Popular scientific lectureKrokan, Hans Einar. (1998) Human uracil-DNA glycosylase:Gene structure, regulation and structural basis for enzyme catalysis. FEBS Silver Jubilee Meeting , Copenhagen, Denmark
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Popular scientific lectureKrokan, Hans Einar. (1998) DNA repair and Cancer. Clinical Implications of Molecular Epidemiology of Human Lung C ancer , Oslo
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Popular scientific lecture
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Popular scientific lectureKrokan, Hans Einar. (1998) Genteknologi og mennesket. Byen, kunnskapen og elven v/Det Kongelige Norske Vitenskapsakad emi , Trondheim
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Popular scientific lectureKrokan, Hans Einar. (1998) Human uracil-DNA glycosylase;Gene structure, regulation and molecular anatomy. , Institute of Biosciences at Novum, Karolinska institute, Stockholm
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Popular scientific lecture
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Popular scientific lectureKrokan, Hans Einar. (1998) Fra en grunnforskers ståsted. ved: Sikring av rettigheter og utnyttelse av forskningsresultater i medisinsk og helsefaglig forskning. Samarbeid grunnforskning-industri. Fra en grunnforskers ståste d. , Kringsjå Kurssenter, Oslo
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Popular scientific lectureKrokan, Hans Einar. (1998) Structural and functional aspects of base exision repair. , Department of Biosciences at Novum, Karolinska Institute, Sweden
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Popular scientific lectureKrokan, Hans Einar. (1998) Structural and functional aspects of base excision repair. Lecture at International Minisymposium. , The national Hospital, Oslo
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Popular scientific lectureKrokan, Hans Einar. (1998) Oversikt over forskningsaktiviteten i DNA-reparasjonsgruppa. Storlienmøte , Storlien
1997
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Popular scientific lectureKrokan, Hans Einar. (1997) Human uracil-DNA glucosylase - genetics and structural-function relationships. 7th International Conference on Environmental Mutagenes , Toulouse
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Popular scientific lectureKrokan, Hans Einar. (1997) Human uracil-DNA glycosylase : gene structure, regulation and structural basis for enzyme catalysis. NATO Study Institute DNA Damage and Repair : Oxygen Radical Ef fects, Cellular P rotection and Biological Consequences , Antalya