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  1. Employees

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Gaston Courtade

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Gaston Courtade

Associate Professor
Department of Biotechnology and Food Science
Faculty of Natural Sciences

gaston.courtade@ntnu.no
+4773590662 Kjemi 4, K4-4.131, Gløshaugen, Sem Sælands vei 6
Google Scholar Courtade Lab Biopolymers and Biomaterials Research Group
About Publications Teaching

About

I am an Associate Professor in Biopolymer Science in the Biopolymer and Biomaterials research group at the Department of Biotechnology and Food Science. My main research interest is the study of the structures and functions of enzymes. In particular, protein dynamics and interactions between proteins and carbohydrates.

More information about the Courtade Lab

Publications

  • Chronological
  • By category
  • See all publications in Cristin

2024

  • Olsen, William P.; Courtade, Gaston; Peña-Díaz, Samuel; Nagaraj, Madhu; Sønderby, Thorbjørn V.; Mulder, Frans A. A.. (2024) CsgA gatekeeper residues control nucleation but not stability of functional amyloid. Protein Science
    Academic article
  • Klein, Vivien Jessica; Troøyen, Susanne Hansen; Fernandes de Brito, Luciana; Courtade, Gaston; Brautaset, Trygve; Irla, Marta Katarzyna. (2024) Identification and characterization of a novel formaldehyde dehydrogenase in Bacillus subtilis. Applied and Environmental Microbiology
    Academic article

2023

  • Østby, Heidi; Christensen, Idd Andrea; Hennum, Karen; Varnai, Aniko; Buchinger, Edith; Grandal, Siri. (2023) Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates. Scientific Reports
    Academic article
  • Christensen, Idd Andrea; Eijsink, Vincent; Stepnov, Anton; Courtade, Gaston; Aachmann, Finn Lillelund. (2023) Following the Fate of Lytic Polysaccharide Monooxygenases under Oxidative Conditions by NMR Spectroscopy. Biochemistry
    Academic article
  • Forsberg, Zarah; Stepnov, Anton; Tesei, Giulio; Wang, Yong; Buchinger, Edith; Kristiansen, Sandra Kvarsvik. (2023) The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase. Journal of Biological Chemistry
    Academic article
  • Fages-Lartaud, Maxime; Mueller, Yasmin; Elie, Florence; Courtade, Gaston; Hohmann-Marriott, Martin Frank. (2023) Standard Intein Gene Expression Ramps (SIGER) for Protein-Independent Expression Control. ACS Synthetic Biology
    Academic article
  • Henning, Per; Brandslet, Steinar; Courtade, Gaston. (2023) Enzymes from bacteria and fungi break down plastic. Norwegian SciTech News
    Popular scientific article

2022

  • Hellesnes, Kristina Naasen; Vijayaraj, Shunmathi; Fojan, Peter; Petersen, Evamaria; Courtade, Gaston. (2022) Biochemical Characterization and NMR Study of a PET-Hydrolyzing Cutinase from Fusarium solani pisi. Biochemistry
    Academic article
  • Forsberg, Zarah; Courtade, Gaston. (2022) On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs). Essays in Biochemistry
    Academic literature review

2021

  • Stepnov, Anton; Christensen, Idd Andrea; Forsberg, Zarah; Aachmann, Finn Lillelund; Courtade, Gaston; Eijsink, Vincent. (2021) The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid. FEBS Letters
    Academic article
  • Madland, Eva; Forsberg, Zarah; Wang, Yong; Lindorff-Larsen, Kresten; Niebisch, Axel; Modregger, Jan. (2021) Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus. Journal of Biological Chemistry
    Academic article

2020

  • Christensen, Idd Andrea; Eijsink, Vincent; Aachmann, Finn Lillelund; Courtade, Gaston. (2020) 1H, 13C, 15N resonance assignment of the apo form of the small, chitin-active lytic polysaccharide monooxygenase JdLPMO10Afrom Jonesia denitrificans. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Ciano, Luisa; Paradisi, Alessandro; Lindley, Peter J.; Forsberg, Zarah; Sørlie, Morten. (2020) Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article
  • Guerrero-Garzón, Jaime Felipe; Madland, Eva; Zehl, Martin; Singh, Madhurendra; Rezaei, Shiva; Aachmann, Finn Lillelund. (2020) Class IV lasso peptides synergistically induce proliferation of cancer cells and sensitize them to doxorubicin. iScience
    Academic article

2019

  • Forsberg, Zarah; Sørlie, Morten; Petrovic, Dejan; Courtade, Gaston; Aachmann, Finn Lillelund; Vaaje-Kolstad, Gustav. (2019) Polysaccharide degradation by lytic polysaccharide monooxygenases. Current Opinion in Structural Biology
    Academic literature review
  • Courtade, Gaston; Aachmann, Finn Lillelund. (2019) Chitin-Active Lytic Polysaccharide Monooxygenases. Springer
    Chapter

2018

  • Petrovic, Dejan; Bissaro, Bastien; Chylenski, Piotr; Skaugen, Morten; Sørlie, Morten; Jensen, Marianne Slang. (2018) Methylation of the N-terminal histidine protects a lytic polysaccharide monooxygenase from auto-oxidative inactivation. Protein Science
    Academic article
  • Courtade, Gaston; Forsberg, Zarah; Heggset, Ellinor Bævre; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation. Journal of Biological Chemistry
    Academic article
  • Kitaoku, Yoshihito; Courtade, Gaston; Petrovic, Dejan; Fukamizo, Tamo; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) Resonance assignments for the apo-form of the cellulose-active lytic polysaccharide monooxygenase TaLPMO9A. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
    Doctoral dissertation

2017

  • Courtade, Gaston; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincentius Gerardus Henricus; Aachmann, Finn Lillelund. (2017) Chemical shift assignments for the apo-form of the catalytic domain, the linker region, and the carbohydrate-binding domain of the cellulose-active lytic polysaccharide monooxygenase ScLPMO10C. Biomolecular NMR Assignments
    Academic article
  • Crasson, Oscar; Courtade, Gaston; Leonard, Raphael R; Aachmann, Finn Lillelund; Legrand, Francois; Parente, Raffaella. (2017) Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function. Scientific Reports
    Academic article
  • Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
    Academic article

2016

  • Courtade, Gaston; Wimmer, Reinhard; Dimarogona, Maria; Sandgren, Mats; Eijsink, Vincent; Aachmann, Finn Lillelund. (2016) Backbone and side-chain 1H, 13C, and 15N chemical shift assignments for the apo-form of the lytic polysaccharide monooxygenase NcLPMO9C. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Wimmer, Reinhard; Kjendseth, Åsmund Røhr; Preims, Marita; Felice, Alfons K.G.; Dimarogona, Maria. (2016) Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article

2015

  • Courtade, Gaston; Balzer, Simone; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincent; Aachmann, Finn Lillelund. (2015) 1H, 13C, 15N resonance assignment of the chitin-active lytic polysaccharide monooxygenase BlLPMO10A from Bacillus licheniformis. Biomolecular NMR Assignments
    Academic article

2014

  • Courtade, Gaston; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2014) Structural Investigation of a Lytic Polysaccharide Monooxygenase by NMR Spectroscopy . NTNU
    Masters thesis
  • Courtade, Gaston; Christensen, Bjørn E.; Ulset, Ann-Sissel Teialeret. (2014) Video demonstration of Biopolymers lab exercises.
    Digital learning tools

2013

  • Gałęcki, Krystian; Courtade, Gaston; McFall, Aisling; Teixeira, Renata Prieschl; Grgic, Maja; Esteve-Sistere, Marta. (2013) Experimental and theoretical investigation of drotaverine binding to bovine serum albumin. Biotechnology and Food Science
    Academic article

Journal publications

  • Olsen, William P.; Courtade, Gaston; Peña-Díaz, Samuel; Nagaraj, Madhu; Sønderby, Thorbjørn V.; Mulder, Frans A. A.. (2024) CsgA gatekeeper residues control nucleation but not stability of functional amyloid. Protein Science
    Academic article
  • Klein, Vivien Jessica; Troøyen, Susanne Hansen; Fernandes de Brito, Luciana; Courtade, Gaston; Brautaset, Trygve; Irla, Marta Katarzyna. (2024) Identification and characterization of a novel formaldehyde dehydrogenase in Bacillus subtilis. Applied and Environmental Microbiology
    Academic article
  • Østby, Heidi; Christensen, Idd Andrea; Hennum, Karen; Varnai, Aniko; Buchinger, Edith; Grandal, Siri. (2023) Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates. Scientific Reports
    Academic article
  • Christensen, Idd Andrea; Eijsink, Vincent; Stepnov, Anton; Courtade, Gaston; Aachmann, Finn Lillelund. (2023) Following the Fate of Lytic Polysaccharide Monooxygenases under Oxidative Conditions by NMR Spectroscopy. Biochemistry
    Academic article
  • Forsberg, Zarah; Stepnov, Anton; Tesei, Giulio; Wang, Yong; Buchinger, Edith; Kristiansen, Sandra Kvarsvik. (2023) The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase. Journal of Biological Chemistry
    Academic article
  • Fages-Lartaud, Maxime; Mueller, Yasmin; Elie, Florence; Courtade, Gaston; Hohmann-Marriott, Martin Frank. (2023) Standard Intein Gene Expression Ramps (SIGER) for Protein-Independent Expression Control. ACS Synthetic Biology
    Academic article
  • Henning, Per; Brandslet, Steinar; Courtade, Gaston. (2023) Enzymes from bacteria and fungi break down plastic. Norwegian SciTech News
    Popular scientific article
  • Hellesnes, Kristina Naasen; Vijayaraj, Shunmathi; Fojan, Peter; Petersen, Evamaria; Courtade, Gaston. (2022) Biochemical Characterization and NMR Study of a PET-Hydrolyzing Cutinase from Fusarium solani pisi. Biochemistry
    Academic article
  • Forsberg, Zarah; Courtade, Gaston. (2022) On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs). Essays in Biochemistry
    Academic literature review
  • Stepnov, Anton; Christensen, Idd Andrea; Forsberg, Zarah; Aachmann, Finn Lillelund; Courtade, Gaston; Eijsink, Vincent. (2021) The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid. FEBS Letters
    Academic article
  • Madland, Eva; Forsberg, Zarah; Wang, Yong; Lindorff-Larsen, Kresten; Niebisch, Axel; Modregger, Jan. (2021) Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus. Journal of Biological Chemistry
    Academic article
  • Christensen, Idd Andrea; Eijsink, Vincent; Aachmann, Finn Lillelund; Courtade, Gaston. (2020) 1H, 13C, 15N resonance assignment of the apo form of the small, chitin-active lytic polysaccharide monooxygenase JdLPMO10Afrom Jonesia denitrificans. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Ciano, Luisa; Paradisi, Alessandro; Lindley, Peter J.; Forsberg, Zarah; Sørlie, Morten. (2020) Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article
  • Guerrero-Garzón, Jaime Felipe; Madland, Eva; Zehl, Martin; Singh, Madhurendra; Rezaei, Shiva; Aachmann, Finn Lillelund. (2020) Class IV lasso peptides synergistically induce proliferation of cancer cells and sensitize them to doxorubicin. iScience
    Academic article
  • Forsberg, Zarah; Sørlie, Morten; Petrovic, Dejan; Courtade, Gaston; Aachmann, Finn Lillelund; Vaaje-Kolstad, Gustav. (2019) Polysaccharide degradation by lytic polysaccharide monooxygenases. Current Opinion in Structural Biology
    Academic literature review
  • Petrovic, Dejan; Bissaro, Bastien; Chylenski, Piotr; Skaugen, Morten; Sørlie, Morten; Jensen, Marianne Slang. (2018) Methylation of the N-terminal histidine protects a lytic polysaccharide monooxygenase from auto-oxidative inactivation. Protein Science
    Academic article
  • Courtade, Gaston; Forsberg, Zarah; Heggset, Ellinor Bævre; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation. Journal of Biological Chemistry
    Academic article
  • Kitaoku, Yoshihito; Courtade, Gaston; Petrovic, Dejan; Fukamizo, Tamo; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) Resonance assignments for the apo-form of the cellulose-active lytic polysaccharide monooxygenase TaLPMO9A. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincentius Gerardus Henricus; Aachmann, Finn Lillelund. (2017) Chemical shift assignments for the apo-form of the catalytic domain, the linker region, and the carbohydrate-binding domain of the cellulose-active lytic polysaccharide monooxygenase ScLPMO10C. Biomolecular NMR Assignments
    Academic article
  • Crasson, Oscar; Courtade, Gaston; Leonard, Raphael R; Aachmann, Finn Lillelund; Legrand, Francois; Parente, Raffaella. (2017) Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function. Scientific Reports
    Academic article
  • Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
    Academic article
  • Courtade, Gaston; Wimmer, Reinhard; Dimarogona, Maria; Sandgren, Mats; Eijsink, Vincent; Aachmann, Finn Lillelund. (2016) Backbone and side-chain 1H, 13C, and 15N chemical shift assignments for the apo-form of the lytic polysaccharide monooxygenase NcLPMO9C. Biomolecular NMR Assignments
    Academic article
  • Courtade, Gaston; Wimmer, Reinhard; Kjendseth, Åsmund Røhr; Preims, Marita; Felice, Alfons K.G.; Dimarogona, Maria. (2016) Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article
  • Courtade, Gaston; Balzer, Simone; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincent; Aachmann, Finn Lillelund. (2015) 1H, 13C, 15N resonance assignment of the chitin-active lytic polysaccharide monooxygenase BlLPMO10A from Bacillus licheniformis. Biomolecular NMR Assignments
    Academic article
  • Gałęcki, Krystian; Courtade, Gaston; McFall, Aisling; Teixeira, Renata Prieschl; Grgic, Maja; Esteve-Sistere, Marta. (2013) Experimental and theoretical investigation of drotaverine binding to bovine serum albumin. Biotechnology and Food Science
    Academic article

Part of book/report

  • Courtade, Gaston; Aachmann, Finn Lillelund. (2019) Chitin-Active Lytic Polysaccharide Monooxygenases. Springer
    Chapter

Report

  • Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
    Doctoral dissertation
  • Courtade, Gaston; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2014) Structural Investigation of a Lytic Polysaccharide Monooxygenase by NMR Spectroscopy . NTNU
    Masters thesis

PRODUKT

  • Courtade, Gaston; Christensen, Bjørn E.; Ulset, Ann-Sissel Teialeret. (2014) Video demonstration of Biopolymers lab exercises.
    Digital learning tools

Teaching

Courses

  • BT3920 - Masteroppgave i biologi ved IBT
  • BT1101 - Introduksjon til bioteknologi
  • TBT4102 - Biokjemi 1
  • BT8136 - Funksjonell enzymkarakterisering ved bruk av NMR (C12)

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