Ellen Røyrvik

Ellen Christine Røyrvik

Ellen Christine Røyrvik

Former Academy Leader

Røyrvik is a geneticist at the Norwegian Institute of Public Health, previously at the K.G. Jebsen Center for Autoimmune Disease. Her work has involved the analysis of DNA and the effects of variation in it, from molecular details of replication processes to population and species levels patterns of genetic variation, and at a time scale from microseconds to billions of years. At the K.G. Jebsen center she elucidated genetic risk variants of autoimmune Addison's disease in both sporadic and familial cases, and contributed to follow-up work assessing the functional relevance of these risk variants. 

Position

Position

Researcher at the Norwegian Institute of Public Health and the University of Bergen

Selected publications

Selected publications

Eriksson, D., Røyrvik, E.C., Aranda-Guillén, M. et al. GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility. Nat Commun 12, 959 (2021).

Ellen C Røyrvik, Iain G Johnston, MtDNA sequence features associated with ‘selfish genomes’ predict tissue-specific segregation and reversion, Nucleic Acids Research, Volume 48, Issue 15, 04 September 2020, Pages 8290–8301

Leslie S, Winney B, Hellenthal G, Davison D, Boumertit A, Day T, Hutnik K, Royrvik EC, Cunliffe B; Wellcome Trust Case Control Consortium 2; International Multiple Sclerosis Genetics Consortium, Lawson DJ, Falush D, Freeman C, Pirinen M, Myers S, Robinson M, Donnelly P, Bodmer W. The fine-scale genetic structure of the British population. Nature. 2015 Mar 19;519(7543):309-314. doi: 10.1038/nature14230. PMID: 25788095; PMCID: PMC4632200.

Project involvement

Project involvement

Røyrvik continues to work on genetic determinants of autoimmune Addison's disease and their systemic and organ-specific effects. Her primary research is currently on the Norwegian Mother, Father and Child Cohort Study, where she is among other things involved in showing how genetics influence side effects of Covid-19 vaccination. As of summer 2023 she will lead a study on the fine-scale population genomics of Norway, secondarily incorporating humanities fields, demography, and medically motivated genetics.