Louise Fremgaard Risnes
Photo: UiO/Øystein H. Horgmo
Louise Fremgaard Risnes
Fremgaard Risnes is a Postdoctoral Fellow at the KG Jebsen Coeliac Disease Research Centre (J CoDiRC). She is an immunologist who has made ground-breaking discoveries on gluten-specific CD4+ T cells in coeliac disease revealing their phenotype, compartment distribution and longevity. Her current research focuses on the role of these T-cells early in disease development.
Position
Postdoctoral Fellow at UiO (UiO profile)
Selected publications
Eggesbø LM, Risnes LF, Neumann RS, Lundin KEA, Christophersen A, Sollid LM.(2020) Single-cell TCR sequencing of gut intraepithelial T cells reveals a vast and diverse repertoire in celiac disease. Mucosal Immunol. 13(2) doi:10.1038/s41385-019-0222-9
Christophersen A, Risnes LF, Dahal-Koirala S, Sollid LM.(2019) Therapeutic and diagnostic implications of T cell scarring in celiac disease and beyond. Review Trends Mol Med. 25(10) doi:10.1016/j.molmed.2019.05.009
Risnes LF, Christophersen A, Dahal-Koirala S, Neumann RS, Sandve GK, Sarna VK, Lundin KE, Qiao SW, Sollid LM.(2018) Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease. J Clin Invest. 128(6) doi:10.1172/JCI98819
Project involvement
Risnes will in her future work study approaches to directly target and eradicate gluten-specific T-cells as a therapeutic option for coeliac disease. This project is performed together with members of the Sollid group and the Lundin group at J CoDiRC.