Bodil Merete Kavli
+4773412716
+4797661442
Laboratoriesenteret, 231.05.011, Øya, Østfløy, 5 etg., Erling Skjalgssons g 1
About
DNA repair and adaptive immunity
How are DNA lesions generated and repaired in our genome? What is the molecular link between DNA repair and adaptive immunity? What goes wrong when normal cells accumulate mutations and transform to cancer cells? These are important questions in my research.
I have for many years worked within the field of DNA repair and genome stability with specific focus on repair of genomic uracil (deaminated cytosine). The work includes structural and functional characterization of the uracil-DNA glycosylases UNG and SMUG1 (Biochemistry 1995; Cell 1995; Nature 1996; Embo J 1996, 2000, 2008; JBC 2002; NAR 2007, 2011; JBC 2011: DNA repair 2012).
Studies of immune-deficient patients with mutations in the UNG gene revealed an essential role of this enzyme also in adaptive immunity (Nature Immunology 2003; JEM 2005). Here, the UNG glycosylase plays a central role during the socondary antibody diversification mechanisms; somatic hyper mutation (SHM) and class switch recombination (CSR).
The primary and physiologically role of activation-induced cytidine deaminase (AID), the master enzyme in adaptive immunity, is to introduce uracil lesions at the Ig loci to initiate antibody diversification.
However, AID and other members of this mutator-protein family (APOBECs) pose a great threat to genomic integrity and mistargeted AID activity is likely a major cause behind oncogenic mutations and translocations in B-cell lymphomas as well as other cancers. Understanding regulation of these dynamic genome processes has during the last years become my major research interest (Nat Struct Mol Biol 2009; JMB 2013; Exp Cell Research 2014; DNA repair 2015).
Publications
2023
-
Hayran , Abdul Baset ;
Liabakk, Nina-Beate;
Aas, Per Arne;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg;
Sarno, Antonio.
(2023)
RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.
Nucleic Acids Research (NAR)
Academic article
2022
-
Halsne, Ruth;
Kavli, Bodil Merete.
(2022)
Cellers replikasjon påvirker translokasjon av DNA.
Tidsskrift for Den norske legeforening
Article in business/trade/industry journal
2021
-
Kavli, Bodil Merete;
Iveland, Tobias Solli;
Buchinger, Edith;
Hagen, Lars;
Liabakk, Nina-Beate;
Aas, Per Arne.
(2021)
RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork.
Nucleic Acids Research (NAR)
Academic article
2020
-
Kavli, Bodil Merete;
Slupphaug, Geir;
Krokan, Hans Einar.
(2020)
Genomic Uracil in Biology, Immunity and Cancer.
Royal Society of Chemistry (RSC) Publishing
Academic chapter/article/Conference paper
2019
-
Sarno, Antonio;
Lundbæk, Marie Benner;
Liabakk, Nina-Beate;
Aas, Per Arne;
Mjelle, Robin;
Hagen, Lars.
(2019)
Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.
Nucleic Acids Research (NAR)
Academic article
2018
-
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Genomic Uracil and Immunity.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Viral Uracil - Uracil DNA glycosylases and dUTPases.
World Scientific
Chapter
-
Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2018)
Routes to Uracil in DNA.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
DNA Repair is Integrated with Many Cellular Processes.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Sarno, Antonio;
Slupphaug, Geir.
(2018)
Enzymology of Genomic Uracil Repair.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir;
Drabløs, Finn.
(2018)
The Earth, Life and Genomic Uracil.
World Scientific
Chapter
-
Sarno, Antonio;
Sætrom, Pål;
Kavli, Bodil Merete;
Pettersen, Henrik Sahlin.
(2018)
Genomic Uracil and Cancer.
World Scientific
Chapter
-
Dewan, Alisa Elinsdatter;
Xing, Mengtan;
Lundbæk, Marie Benner;
Gago-Fuentes, Raquel;
Beck, Carole;
Aas, Per Arne.
(2018)
Robust DNA repair in PAXX-deficient mammalian cells.
FEBS Open Bio
Academic article
2017
-
Buchinger, Edith;
Wiik, Siv Åshild;
Kusnierczyk, Anna;
Rabe, Renana;
Aas, Per Arne;
Kavli, Bodil Merete.
(2017)
Backbone 1H, 13C and 15N chemical shift assignment of full-length human uracil DNA glycosylase UNG2.
Biomolecular NMR Assignments
Academic article
-
Krokan, Hans Einar;
Slupphaug, Geir;
Kavli, Bodil Merete.
(2017)
Genomic Uracil-Dangers and Benefits in processing.
Academic chapter/article/Conference paper
2015
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Academic article
2014
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Academic article
-
Hu, Yi;
Ericsson, Ida;
Doseth, Berit;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2014)
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors.
Experimental Cell Research
Academic article
-
Wallenius, Anders;
Hauser, Jannek;
Aas, Per Arne;
Sarno, Antonio;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2014)
Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification.
Molecular Immunology
Academic article
2013
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Ericsson, Ida;
Galashevskaya, Anastasia;
Sarno, Antonio;
Aas, Per Arne.
(2013)
Genomic uracil - potent mutagen but normal intermediate in adaptive immunity.
The FEBS Journal
Abstract
-
Hu, Yi;
Ericsson, Ida;
Torseth, Kathrin;
Methot, Stephen;
Sundheim, Ottar;
Liabakk, Nina-Beate.
(2013)
A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
Journal of Molecular Biology (JMB)
Academic article
2012
-
Torseth, Kathrin;
Doseth, Berit;
Hagen, Lars;
Olaisen, Camilla;
Liabakk, Nina-Beate;
Græsmann, Heidi.
(2012)
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.
DNA Repair
Academic article
-
Doseth, Berit;
Ekre, Cecilie;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2012)
Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
DNA Repair
Academic article
2011
-
Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR)
Academic article
-
Doseth, Berit;
Visnes, Torkild;
Wallenius, Anders;
Ericsson, Ida;
Sarno, Antonio;
Pettersen, Henrik Sahlin.
(2011)
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE.
Journal of Biological Chemistry
Academic article
2010
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Otterlei, Marit;
Akbari, M.;
Slupphaug, Geir;
Aas, Per Arne.
(2010)
DNA repair and cancer.
European Journal of Cancer
Abstract
2009
-
Visnes, Torkild;
Doseth, Berit;
Pettersen, Henrik Sahlin;
Hagen, Lars;
Sousa, Mirta;
Akbari, Mansour.
(2009)
Uracil in DNA and its processing by different DNA glycosylases.
Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic literature review
-
Patenaude, AM;
Orthwein, A;
Hu, Yi;
Campo, VA;
Kavli, Bodil Merete;
Buschiazzo, A.
(2009)
Active nuclear import and cytoplasmic retention of activation-induced deaminase.
Nature Structural & Molecular Biology
Academic article
2008
-
Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry
Academic article
-
Hagen, Lars;
Kavli, Bodil Merete;
Sousa, Mirta;
Torseth, Kathrin;
Liabakk, Nina-Beate;
Sundheim, Ottar.
(2008)
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
EMBO Journal
Academic article
2007
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Akbari, Mansour;
Visnes, Torkild;
Pettersen, Henrik P Sahlin;
Sundheim, Ottar.
(2007)
Repair og uracil in DNA by UNG2 and SMUG1 - an update.
DNA Repair
Abstract
-
Pettersen, Henrik P Sahlin;
Sundheim, Ottar;
Gilljam, Karin Margaretha;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2007)
Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.
Nucleic Acids Research (NAR)
Academic article
-
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
Uracil in DNA - General mutagen, but normal intermediate in acquired immunity.
DNA Repair
Academic article
-
Parsons, Jason L.;
Kavli, Bodil Merete;
Slupphaug, Geir;
Dianov, Grigory L..
(2007)
NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break.
Biochemistry
Academic article
2006
-
Hagen, Lars;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2006)
Genomic uracil and human disease.
Experimental Cell Research
Academic literature review
-
Krokan, Hans Einar;
Akbari, Mansour;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Ericsson, Madelene.
(2006)
Base excision repair proteins in cancer prevention and acquired immune responses.
The FEBS Journal
Abstract
2005
-
Zeitlin, SG;
Patel, S;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2005)
Xenopus CENP - A assembly into chromatin requires base excision repair proteins.
DNA Repair
Academic article
-
Kavli, Bodil Merete;
Andersen, Sonja Benedikte;
Otterlei, Marit;
Liabakk, Nina-Beate;
Imai, K;
Fischer, A.
(2005)
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
Journal of Experimental Medicine (JEM)
Academic article
2004
-
Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair
Academic literature review
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Aas, Per Arne;
Kavli, Bodil;
Liabakk, Nina-Beate.
(2004)
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.
Nucleic Acids Research (NAR)
Academic article
2003
-
Scaramozzino, N;
Sanz, G;
Crance, J.M;
Saparbaev, M;
Drillien, R;
Laval, J.
(2003)
Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Slupphaug, Geir;
Kavli, Bodil;
Krokan, Hans Einar.
(2003)
Interacting pathways that prevent and repair oxidative DNA damage.
Mutation Research (DNA Repair)
Academic article
-
Imai, K;
Slupphaug, Geir;
Lee, W-I;
Revy, P;
Nonoyama, S;
Catalan, N.
(2003)
Uracil-DNA glycosylase deficiency profoundly impairs immunoglobulin class switch.
Nature Immunology
Academic article
2002
-
Kavli, Bodil;
Sundheim, Ottar;
Akbari, Mansour;
Otterlei, Marit;
Nilsen, Hilde;
Skorpen, Frank.
(2002)
hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup.
Journal of Biological Chemistry
Academic article
2001
-
Krokan, Hans Einar;
Otterlei, Marit;
Nilsen, Hilde;
Kavli, Bodil;
Skorpen, Frank;
Andersen, Sonja.
(2001)
Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene.
Progress in Nucleic Acid Research and Molecular Biology
Academic article
-
Kavli, Bodil.
(2001)
Human uracil-DNA glycosylases from the UNG gene: Structural basis for substrate spesificity and repair.
NTNU, Trondheim
Doctoral dissertation
2000
-
Otterlei, Marit;
Kavli, B;
Standal, R;
Skjelbred, Camilla;
Bharati, S;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Otterlei, Marit;
Kavli, Bodil;
Standal, Rune;
Skjelbred, Camilla;
Bharati, Sangeeta;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
1999
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bhariti, Sangeeta;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1999)
Human uracil-DNA glycosylase.
NATO Advances Study Institute series. Series A, Life sciences
Academic article
1998
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bharati, S;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1998)
Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis.
DNA damage and repair: Oxygen Radical Effects, Cellular Prote ction and Biological Consequences.
Non-fiction book
1996
-
Slupphaug, Geir;
Kavli, B.;
Mol, C.D.;
Arvai, A.;
Krokan, Hans Einar;
Tainer, J.A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Kavli, B.;
Slupphaug, Geir;
Mol, C.D.;
Arvai, A.S.;
Petersen, S.B.;
Tainer, J.A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Kavli, Bodil;
Slupphaug, Geir;
Mol, Clifford D.;
Arvai, Andrew S.;
Petersen, Steffen B.;
Tainer, John A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Slupphaug, Geir;
Mol, Clifford D.;
Kavli, Bodil;
Arvai, Andrew S.;
Krokan, Hans Einar;
Tainer, John A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
1995
-
Slupphaug, Geir;
Eftedal, Ingrid;
Kavli, Bodil;
Bharati, Sangeeta;
Helle, Nils M;
Haug, Terje.
(1995)
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase.
Biochemistry
Academic article
Journal publications
-
Hayran , Abdul Baset ;
Liabakk, Nina-Beate;
Aas, Per Arne;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg;
Sarno, Antonio.
(2023)
RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.
Nucleic Acids Research (NAR)
Academic article
-
Halsne, Ruth;
Kavli, Bodil Merete.
(2022)
Cellers replikasjon påvirker translokasjon av DNA.
Tidsskrift for Den norske legeforening
Article in business/trade/industry journal
-
Kavli, Bodil Merete;
Iveland, Tobias Solli;
Buchinger, Edith;
Hagen, Lars;
Liabakk, Nina-Beate;
Aas, Per Arne.
(2021)
RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork.
Nucleic Acids Research (NAR)
Academic article
-
Sarno, Antonio;
Lundbæk, Marie Benner;
Liabakk, Nina-Beate;
Aas, Per Arne;
Mjelle, Robin;
Hagen, Lars.
(2019)
Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.
Nucleic Acids Research (NAR)
Academic article
-
Dewan, Alisa Elinsdatter;
Xing, Mengtan;
Lundbæk, Marie Benner;
Gago-Fuentes, Raquel;
Beck, Carole;
Aas, Per Arne.
(2018)
Robust DNA repair in PAXX-deficient mammalian cells.
FEBS Open Bio
Academic article
-
Buchinger, Edith;
Wiik, Siv Åshild;
Kusnierczyk, Anna;
Rabe, Renana;
Aas, Per Arne;
Kavli, Bodil Merete.
(2017)
Backbone 1H, 13C and 15N chemical shift assignment of full-length human uracil DNA glycosylase UNG2.
Biomolecular NMR Assignments
Academic article
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Academic article
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Academic article
-
Hu, Yi;
Ericsson, Ida;
Doseth, Berit;
Liabakk, Nina-Beate;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2014)
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors.
Experimental Cell Research
Academic article
-
Wallenius, Anders;
Hauser, Jannek;
Aas, Per Arne;
Sarno, Antonio;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2014)
Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification.
Molecular Immunology
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Ericsson, Ida;
Galashevskaya, Anastasia;
Sarno, Antonio;
Aas, Per Arne.
(2013)
Genomic uracil - potent mutagen but normal intermediate in adaptive immunity.
The FEBS Journal
Abstract
-
Hu, Yi;
Ericsson, Ida;
Torseth, Kathrin;
Methot, Stephen;
Sundheim, Ottar;
Liabakk, Nina-Beate.
(2013)
A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
Journal of Molecular Biology (JMB)
Academic article
-
Torseth, Kathrin;
Doseth, Berit;
Hagen, Lars;
Olaisen, Camilla;
Liabakk, Nina-Beate;
Græsmann, Heidi.
(2012)
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.
DNA Repair
Academic article
-
Doseth, Berit;
Ekre, Cecilie;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2012)
Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
DNA Repair
Academic article
-
Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR)
Academic article
-
Doseth, Berit;
Visnes, Torkild;
Wallenius, Anders;
Ericsson, Ida;
Sarno, Antonio;
Pettersen, Henrik Sahlin.
(2011)
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE.
Journal of Biological Chemistry
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Otterlei, Marit;
Akbari, M.;
Slupphaug, Geir;
Aas, Per Arne.
(2010)
DNA repair and cancer.
European Journal of Cancer
Abstract
-
Visnes, Torkild;
Doseth, Berit;
Pettersen, Henrik Sahlin;
Hagen, Lars;
Sousa, Mirta;
Akbari, Mansour.
(2009)
Uracil in DNA and its processing by different DNA glycosylases.
Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic literature review
-
Patenaude, AM;
Orthwein, A;
Hu, Yi;
Campo, VA;
Kavli, Bodil Merete;
Buschiazzo, A.
(2009)
Active nuclear import and cytoplasmic retention of activation-induced deaminase.
Nature Structural & Molecular Biology
Academic article
-
Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry
Academic article
-
Hagen, Lars;
Kavli, Bodil Merete;
Sousa, Mirta;
Torseth, Kathrin;
Liabakk, Nina-Beate;
Sundheim, Ottar.
(2008)
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
EMBO Journal
Academic article
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Akbari, Mansour;
Visnes, Torkild;
Pettersen, Henrik P Sahlin;
Sundheim, Ottar.
(2007)
Repair og uracil in DNA by UNG2 and SMUG1 - an update.
DNA Repair
Abstract
-
Pettersen, Henrik P Sahlin;
Sundheim, Ottar;
Gilljam, Karin Margaretha;
Slupphaug, Geir;
Krokan, Hans Einar;
Kavli, Bodil Merete.
(2007)
Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.
Nucleic Acids Research (NAR)
Academic article
-
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
Uracil in DNA - General mutagen, but normal intermediate in acquired immunity.
DNA Repair
Academic article
-
Parsons, Jason L.;
Kavli, Bodil Merete;
Slupphaug, Geir;
Dianov, Grigory L..
(2007)
NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break.
Biochemistry
Academic article
-
Hagen, Lars;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2006)
Genomic uracil and human disease.
Experimental Cell Research
Academic literature review
-
Krokan, Hans Einar;
Akbari, Mansour;
Diaz, Javier Pena;
Kavli, Bodil Merete;
Otterlei, Marit;
Ericsson, Madelene.
(2006)
Base excision repair proteins in cancer prevention and acquired immune responses.
The FEBS Journal
Abstract
-
Zeitlin, SG;
Patel, S;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2005)
Xenopus CENP - A assembly into chromatin requires base excision repair proteins.
DNA Repair
Academic article
-
Kavli, Bodil Merete;
Andersen, Sonja Benedikte;
Otterlei, Marit;
Liabakk, Nina-Beate;
Imai, K;
Fischer, A.
(2005)
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
Journal of Experimental Medicine (JEM)
Academic article
-
Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair
Academic literature review
-
Akbari, Mansour;
Otterlei, Marit;
Diaz, Javier Pena;
Aas, Per Arne;
Kavli, Bodil;
Liabakk, Nina-Beate.
(2004)
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.
Nucleic Acids Research (NAR)
Academic article
-
Scaramozzino, N;
Sanz, G;
Crance, J.M;
Saparbaev, M;
Drillien, R;
Laval, J.
(2003)
Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase.
Nucleic Acids Research (NAR)
Academic article
-
Slupphaug, Geir;
Kavli, Bodil;
Krokan, Hans Einar.
(2003)
Interacting pathways that prevent and repair oxidative DNA damage.
Mutation Research (DNA Repair)
Academic article
-
Imai, K;
Slupphaug, Geir;
Lee, W-I;
Revy, P;
Nonoyama, S;
Catalan, N.
(2003)
Uracil-DNA glycosylase deficiency profoundly impairs immunoglobulin class switch.
Nature Immunology
Academic article
-
Kavli, Bodil;
Sundheim, Ottar;
Akbari, Mansour;
Otterlei, Marit;
Nilsen, Hilde;
Skorpen, Frank.
(2002)
hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup.
Journal of Biological Chemistry
Academic article
-
Krokan, Hans Einar;
Otterlei, Marit;
Nilsen, Hilde;
Kavli, Bodil;
Skorpen, Frank;
Andersen, Sonja.
(2001)
Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene.
Progress in Nucleic Acid Research and Molecular Biology
Academic article
-
Otterlei, Marit;
Kavli, B;
Standal, R;
Skjelbred, Camilla;
Bharati, S;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Otterlei, Marit;
Kavli, Bodil;
Standal, Rune;
Skjelbred, Camilla;
Bharati, Sangeeta;
Krokan, Hans Einar.
(2000)
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
EMBO Journal
Academic article
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bhariti, Sangeeta;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1999)
Human uracil-DNA glycosylase.
NATO Advances Study Institute series. Series A, Life sciences
Academic article
-
Slupphaug, Geir;
Kavli, B.;
Mol, C.D.;
Arvai, A.;
Krokan, Hans Einar;
Tainer, J.A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Kavli, B.;
Slupphaug, Geir;
Mol, C.D.;
Arvai, A.S.;
Petersen, S.B.;
Tainer, J.A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Kavli, Bodil;
Slupphaug, Geir;
Mol, Clifford D.;
Arvai, Andrew S.;
Petersen, Steffen B.;
Tainer, John A..
(1996)
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal
Academic article
-
Slupphaug, Geir;
Mol, Clifford D.;
Kavli, Bodil;
Arvai, Andrew S.;
Krokan, Hans Einar;
Tainer, John A..
(1996)
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.
Nature
Academic article
-
Slupphaug, Geir;
Eftedal, Ingrid;
Kavli, Bodil;
Bharati, Sangeeta;
Helle, Nils M;
Haug, Terje.
(1995)
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase.
Biochemistry
Academic article
Books
-
Krokan, Hans Einar;
Skorpen, Frank;
Otterlei, Marit;
Bharati, S;
Steinsbekk, Kristin;
Nilsen, Hilde.
(1998)
Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis.
DNA damage and repair: Oxygen Radical Effects, Cellular Prote ction and Biological Consequences.
Non-fiction book
Part of book/report
-
Kavli, Bodil Merete;
Slupphaug, Geir;
Krokan, Hans Einar.
(2020)
Genomic Uracil in Biology, Immunity and Cancer.
Royal Society of Chemistry (RSC) Publishing
Academic chapter/article/Conference paper
-
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Genomic Uracil and Immunity.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
Viral Uracil - Uracil DNA glycosylases and dUTPases.
World Scientific
Chapter
-
Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2018)
Routes to Uracil in DNA.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2018)
DNA Repair is Integrated with Many Cellular Processes.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Sarno, Antonio;
Slupphaug, Geir.
(2018)
Enzymology of Genomic Uracil Repair.
World Scientific
Chapter
-
Krokan, Hans Einar;
Kavli, Bodil Merete;
Slupphaug, Geir;
Drabløs, Finn.
(2018)
The Earth, Life and Genomic Uracil.
World Scientific
Chapter
-
Sarno, Antonio;
Sætrom, Pål;
Kavli, Bodil Merete;
Pettersen, Henrik Sahlin.
(2018)
Genomic Uracil and Cancer.
World Scientific
Chapter
-
Krokan, Hans Einar;
Slupphaug, Geir;
Kavli, Bodil Merete.
(2017)
Genomic Uracil-Dangers and Benefits in processing.
Academic chapter/article/Conference paper
Report
-
Kavli, Bodil.
(2001)
Human uracil-DNA glycosylases from the UNG gene: Structural basis for substrate spesificity and repair.
NTNU, Trondheim
Doctoral dissertation
Teaching
Courses
Knowledge Transfer
2023
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Academic lectureKavli, Bodil Merete. (2023) Uracil-DNA glycosylase(UNG)-one enzyme-many functions ...how to be in the right place at the right time… . IKOM Monday meeting - Untit of Labarotory Mediscine , NTNU-Lab senter 2023-08-21 -
2021
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Academic lectureKavli, Bodil Merete. (2021) How to repair DNA lesions in single stranded DNA at the replication fork. Marit Otterlei-IKOM-Faggruppe for laboratoriemedisin-NTNU Mandagsforedrag - Faggruppe for laboratoriemedisin , Trondheim 2021-01-18 - 2021-01-18
2019
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Academic lectureKavli, Bodil Merete. (2019) Identification of novel biomarkers in B-cell lymphomas . Fagruppe for laboratoriemedisin Workshop LABMED: From basic to translational research , Trondheim, Laboratoriesenteret Øya 2019-11-11 - 2019-11-11
2018
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LectureKavli, Bodil Merete. (2018) Cytidin deaminaser - Sentrale aktører i immunforsvaret, men også en viktig kilde til mutasjoner og kreft . NTNU-IKOM Prøveforelesning for professorat 2018-11-26 -
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LectureKavli, Bodil Merete. (2018) DNA repair, adaptive immunity and B-cell lymphoma - Its all about genomic uracil.... Magnar Bjørås IKOM Seminar Faggruppe for Laboratoriemedisin , NTNU 2018-10-29 -
2017
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Academic lectureKavli, Bodil Merete. (2017) DNA repair, adaptive immunity and B-cell lymphoma. Magnar Bjørås Trondheim-Oslo Genome Dynamics Workkshop , Scandic hotel Lerkendal 2017-06-15 - 2017-06-16
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Popular scientific lectureKavli, Bodil Merete. (2017) DNA-reparasjon og immunforsvar - Hva er sammenhengen?. DKNVS Akademiet Møte i Det Kongelige Norske Videnskapers Selskabs Akademi , DKNVS Elvegata 17, Trondheim 2017-02-06 - 2017-07-06
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PosterLundbæk, Marie Benner; Sarno, Antonio; Liabakk, Nina-Beate; Aas, Per Arne; Krokan, Hans Einar; Kavli, Bodil Merete. (2017) Mitochondrial uracil-DNA glycosylase UNG1 supports class switch recombination and genomic uracil processing in mouse B-cell. Keystone B-cells and T Follicular Helper cells: Controling Long-Lived Immunity , Whistler 2017-04-23 - 2017-04-27
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Academic lectureKavli, Bodil Merete. (2017) Genomic Uracil-Introduction and Processing in Immunity. NTNU Unit meeting 2017-03-13 - 2017-03-13
2016
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Academic lectureKavli, Bodil Merete; Lundbæk, Marie Benner; Sarno, Antonio; Liabakk, Nina-Beate. (2016) New results and ongoing research related to deaminases. Svend Petersen-Mahrt IFOM 1st DeamiNET meeting , UFOM-Milano 2016-11-10 - 2016-11-11
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LectureKavli, Bodil Merete. (2016) Genomic uracil - General mutagic DNA lesion and Specific intermediate in immunity. Barbara van Loon 1st minisymposium "DNA repair, Epigenetics and Traslational medicine" , NTNU - kunnskapssenteret 2016-09-22 - 2016-09-23
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Academic lectureKrokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan , Matsue 2016-11-13 - 2016-11-17
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Academic lectureKavli, Bodil Merete; Pettersen, Henrik Sahlin; Ericsson, Ida; Hu, Yi; Krokan, Hans Einar. (2016) AID og genomisk uracil; kilde til mutasjoner og utvikling av B-celle lymphom. Onkologisk forum Onkologisk forum 2016 , Scandic hotel- Lerkendal, Trondheim 2016-11-17 - 2016-11-18
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Academic lectureLundbæk, Marie Benner; Sarno, Antonio; Liabakk, Nina-Beate; Krokan, Hans Einar; Kavli, Bodil Merete. (2016) Mitochondrial UNG1 supports class switch recombination in mouse B-cells. 10th 3R Symposium Organzing Committee 10th 3R International Symposium , Matsue 2016-11-13 - 2016-11-17
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Academic lectureKrokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. Russian Academy of Sciences, Siberian branch 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology , Akademorodok, Novosibirsk 2016-08-29 - 2016-09-03
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LectureKrokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Turkish Society of Toxicology. Eurotox 2016 , Sivilla 2016-09-04 -
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Academic lectureKrokan, Hans Einar; Kavli, Bodil Merete; Slupphaug, Geir. (2016) DNA Repair in diagnosis and therapy of cancer - opportunities and problems. NTNU 1st International NTNU Symposium on Clinical Biomarkers of Cancer , Trondheim 2016-06-16 - 2016-06-17
2015
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Academic lectureKavli, Bodil Merete. (2015) AID and BER enzymes in Adaptive Immunity and Genomic Integrity. Zing Conferences Genomic Interity Conference 2015 , Cairns 2015-08-01 - 2015-08-05
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Academic lectureKavli, Bodil Merete. (2015) Activation-induced cytidine deaminase and base excision repair in adaptive immunity. IKM-NTNU Onsdagsmøte IKM , Trondheim 2015-09-02 -
2014
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LectureKavli, Bodil Merete. (2014) Identification of the AID interactome. Faggruppe for Molekylærbiologi Gruppemøte, Faggruppe for molekylærbiologi , NTNU 2014-10-13 - 2014-10-13
2013
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Academic lectureKavli, Bodil Merete. (2013) "Nuclear Import Rate and Deaminase Activity of AID Control Ig Class Switching". IKM Onsdagseminar , NTNU 2013-01-09 -
2012
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Academic lectureKavli, Bodil Merete. (2012) "Regulation of AID". Instituttgruppe for molekylærbiologi Mandagsmøte 2012-10-22 -
2011
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PosterPettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir. (2011) UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. UiO 4th EU-USA conference on DNA base damage and repair , Holmenkollen Park Hotell 2011-05-18 - 2011-05-22
2010
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Academic lectureHagen, Lars; Kavli, Bodil Merete; Sousa, Mirta; Torseth, Kathrin; Slupphaug, Geir. (2010) Post translational modifications of the human DNA repair protein uracil DNA glycosylase, UNG2. 6th Norwegian National Proteomics Meeting 2010-12-09 - 2010-12-10
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Academic lectureKavli, Bodil Merete. (2010) Adaptive immunity - Essential for survival, but with risk for cancer. Jon lamvik onsdagsmøte -IKM , NTNU 2010-09-29 -
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InterviewKavli, Bodil Merete. (2010) "Sammenhengen mellom betennelse og kreft". Her og nå, NRK p1 Her og nå, NRK p1 [Radio] 2010-11-01
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Academic lectureKavli, Bodil Merete. (2010) Ervervet immunitet- nødvendig for overlevelse, men med risiko for kreft. Fagdagene, åpning av nytt sykehus, St Olav , ST.Olav og NTNU 2010-06-10 -
2009
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Academic lectureSlupphaug, Geir; Doseth, Berit; Kavli, Bodil Merete; Visnes, Torkild; Hagen, Lars; Torseth, Kathrin. (2009) Genomic uracil processing in mice and men. 2.nd Erling Seeberg symposium on DNA repair , Ålesund/Geiranger 2009-06-20 - 2009-06-25
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Academic lectureKrokan, Hans Einar; Visnes, Torkild; Doseth, Berit; Akbari, Mansour; Otterlei, Marit; Kavli, Bodil Merete. (2009) Uracil in DNA and its processing. E. Dogliotti, H. Krokan, T. Stevnsner, S. Mitra, S.H. Wilson 3rd US-EU Conference- Repair of Endogenous Genome Damage , Moody Gardens Hotel, Galveston, Texas 2009-02-21 - 2009-02-25
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Academic lectureHu, Yi; Kavli, Bodil Merete. (2009) The mutator enzyme AID; how is the intracellular localization regulated?. IKM tirsdagsmøte , Lab sentret 2009-11-03 -
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PosterHenrik Sahlin, Pettersen; Visnes, Torkild; Vågbø, Cathrine Broberg; Kavli, Bodil Merete; Krokan, Hans Einar. (2009) Cytotoxicity of 5-fluorouracil is mainly due to RNA effects and thymidylate synthase inhibition, not excessive DNA repair. Rikshospitalet-Radiumhospitalet og Universitetet i Oslo 2nd Erling Seeberg Symposium on DNA Repair , Ålesund og Geiranger 2009-06-20 - 2009-06-25
2008
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Academic lectureKavli, Bodil Merete. (2008) Two levels of protection for the B cell genome during somatic hypermutation. Mandagsmøte IKM 2008-05-25 -
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Academic lectureSlupphaug, Geir; Westbye, Marianne P.; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi. (2008) Human ABH1 is a predominantly mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Ist Russian-EU meeting in Genomic maintenance , St. Petersburg 2008-06-24 - 2008-06-26
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Popular scientific lectureKavli, Bodil Merete. (2008) Uracil i DNA. Bodil Kavli i samarbeid med byåsen videregående skole Foredrag for Bioligistudenter fra Byåsen videregående skole , Laboratoriesenteret, NTNU 2008-03-26 -
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Popular scientific lectureKavli, Bodil Merete. (2008) Uracil i DNA; generelt mutagen og viktig mellomprodukt i adaptiv immunitet. Silja Strand Storbakken, Byåsen videregående skole Fagdag i biologi for biologilærere i videregående skole 2008-10-30 -
2007
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Academic lectureVisnes, Torkild; Kavli, Bodil Merete; Pettersen, Henrik P Sahlin; Krokan, Hans Einar. (2007) Efficient repair of 5-fluorouracil from DNA by base excision repair: roles of UNG2 and SMUG1. EU EU - IP DNA Repair workshop for young scientists , Gent 2007-05-13 - 2007-05-16
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Academic lectureKavli, Bodil Merete. (2007) UNG2 and SMUG1 coordinate the initial steps in BER by different mechanisms. IKMM Mandagsforedrag IKMM , Trondheim 2007-05-14 -
2006
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Academic lectureKavli, Bodil Merete. (2006) Uracil i DNA; Generelt mutagen og viktig intermediat i adaptive immunitet. Gjesteforelesning for elever ved Høyskolen i Oslo 2006-10-05 -
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Academic lectureKavli, Bodil Merete. (2006) UNG2; betydning for utvikling av humaoral immunitet. Institutt seminar 2006-11-28 -
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PosterHagen, Lars; Kavli, Bodil Merete; Sundheim, Ottar; Sousa, Mirta; Otterlei, Marit; Liabakk, Nina-Beate. (2006) Regulation of uracil base excision repair by post-translational modifications. Erling Seeberg Symposium on DNA Repair 2006-05-28 - 2006-06-02
2005
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PosterKavli, Bodil Merete; Diaz, Javier Pena; Otterlei, Marit; Liabakk, Nina-Beate; Giljam, Karin Margaretha; Krokan, Hans Einar. (2005) The enzymatic activity of human uracil-DNA glycosylase UNG2 is regulated by N-terminal phosphorylation during cell cycle. Instituto Superiore di Sanita/EMBO 2nd EU-US DNA Repair Meeting: Endogeneous Stress, Base excision repair and related processes , Erice, Sicily 2005-11-28 - 2005-12-03
2004
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PosterKavli, Bodil; Otterlei, Marit; Liabakk, Nina-Beate; Krokan, Hans Einar; Slupphaug, Geir. (2004) The mutant UNG2-F-25 1S associated with HIGM syndrome is abnormally translocated and degraded, and results in impaired nuclear uracil excision and accumulation of genomic uracil. ASM Conference on DNA Repair and Mutagenesis , Bermuda 2004-11-14 - 2004-11-20
2003
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Popular scientific lectureKavli, Bodil. (2003) AID og UNG; Nøkkelenzymer i affinitetsmodning av immunoglobuliner og klasse-switch. "Tirsdagsmøte" , Trondheim, Norge 2003-03-11 -
2002
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Academic lectureKavli, Bodil. (2002) PCR - polymerase chain reaction. GENTEKNOLOGI - Kurs for lærere . Norgesnettrådet , Trondheim, Norge 2002-10-31 -
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PosterKavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Aas, Per Arne; Otterlei, Marit; Skorpen, Frank. (2002) Biochemical and kinetic analysis of human UNG2 and SMUG1 indicate overlapping functions in DNA-uracil repair in the nucleus. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life , Quality Hotel Røros 2002-01-20 -
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PosterKavli, Bodil; Otterlei, Marit; Sundheim, Ottar; Akbari, Mansour; Aas, Per Arne; Krokan, Hans Einar. (2002) Biochemical and kinetic analysis of human UNG2 and SMUG1 indicate overlapping functions in uracil-DNA repair in the nucleus. Mutagenesis and Carcinogenesis, Gordon Research Conference , Ventura, California, USA 2002-03-08 -
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PosterKavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Aas, Per Arne. (2002) Substrate preference and enzyme kinetics reveal distinct properties of UNG2 and SMUG1 in cellular base-excision repair; hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches and U in single stranded DNA, with hSMUG1 as a broad specificity backup. 32nd Annual Meeting of European Environmental Mutagen Society. DNA Damage and Repair Fundamental Aspects and Contribution to Human Disorders , Warsaw. Poland 2002-09-07 -
2001
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PosterSundheim, Ottar; Otterlei, Marit; Kavli, Bodil; Skorpen, Frank; Aas, Per Arne; Krokan, Hans Einar. (2001) Structure-function analysis of the human uracil-DNA glycosylase hSMUG1. Sixth International School on the Crystallography of Biological Macromolecules. , Como, Italy 2001-05-17 -
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Popular scientific lectureKavli, Bodil. (2001) Human uracil DNA glucosylases from UNG-gene. Structural basis for substrate specificity and repair. "Tirsdagsmøte" populærvitenskapelig foredrag. , Medisinsk Teknisk Senter 2001-04-17 -
2000
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Popular scientific lectureKrokan, Hans Einar; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank; Andersen, Sonja. (2000) Structure-function aspects of human uracil-DNA glycosylase and its interactions with other proteins. DNA Base Excision Repair Workshop (BER 2000 WORKSHOP) , Galveston, Texas, March 10 - 13, 2000
1999
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PosterKrokan, Hans Einar; Slupphaug, Geir; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank. (1999) Excicion Repar of DNA Damage 1. , 1-7 november 1999
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PosterOtterlei, Marit; Kavli, B.; Standal, R.; Skjelbred, Camilla; Bharati, S.; Krokan, Hans Einar. (1999) In vivo Repair of AP-sites in the E.coli Chromosome. , 1-7 november 1999
1998
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PosterKavli, Bodil; Otterlei, Marit; Skjelbred, Camilla; Standal, Rune; Bharati, Sangeeta; Krokan, Hans Einar. (1998) Mutation frequency and mutation spectra caused by chromosomal AP-site in repair deficient E.coli strains. Norsk Biokjemisk Selskaps møte , Lillehammer
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Popular scientific lectureKavli, Bodil. (1998) Kartlegging av protein struktur/funksjon vha setespesifikk mutagenese og røntgenkrystallografi. Storlienmøte , Storlien