Ben Michael Brumpton
+4773597564
+4746229495
Øya Helsehus, 153.04.020, Øya, Håkon Jarls gate 11
About
My research concerns the use of genetic data and phenotypic information collected from population-based health surveys, electronic health records and other omics within epidemiological frameworks to make causal inference. My methodologies include Mendelian randomization and genetic epidemiology.
Major research projects:
- HUNT genotyping
- HUNT-COVID questionnaire
- HUNT-metabolomics
- HUNT-methylation
Competencies
Publications
2022
-
Howe, Laurence J.;
Brumpton, Ben Michael;
Rasheed, Humaira;
Åsvold, Bjørn Olav;
Davey Smith, George;
Davies, Neil Martin.
(2022)
Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study.
eLIFE
Academic article
2021
-
Bhatta, Laxmi;
Cepelis, Aivaras;
Vikjord, Sigrid Anna Aalberg;
Malmo, Vegard;
Laugsand, Lars Erik;
Dalen, Håvard.
(2021)
Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study.
European Journal of Epidemiology (EJE)
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics
Academic article
2020
-
Zhou, Wei;
Brumpton, Ben Michael;
Kabil, Omer;
Gudmundsson, Julius;
Thorleifsson, Gudmar;
Weinstock, Joshua.
(2020)
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.
Nature Communications
Academic article
-
Surakka, Ida;
Fritsche, Lars;
Zhou, Wei;
Backman, Joshua;
Kosmicki, Jack A.;
Lu, Haocheng.
(2020)
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Nature Communications
Academic article
-
Nielsen, Jonas Bille;
Rom, Oren;
Surakka, Ida;
Graham, Sarah E.;
Zhou, Wei;
Roychowdhury, Tanmoy.
(2020)
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Academic article
-
Brumpton, Ben Michael;
Sanderson, Eleanor;
Heilbron, Karl;
Hartwig, FP;
Harrison, S;
Vie, Gunnhild Åberge.
(2020)
Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses.
Nature Communications
Academic article
-
Moen, Gunn-Helen;
Brumpton, Ben Michael;
Willer, Cristen J.;
Åsvold, Bjørn Olav;
Birkeland, Kåre I.;
Wang, Geng.
(2020)
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort.
Nature Communications
Academic article
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Yue, Chen.
(2020)
Spirometric Classifications of COPD Severity as Predictive
Markers for Clinical Outcomes: The HUNT Study.
American Journal of Respiratory and Critical Care Medicine
Academic article
2019
-
Budu-Aggrey, Ashley;
Brumpton, Ben Michael;
Tyrrell, Jess;
Watkins, Sarah;
Modalsli, Ellen Heilmann;
Celis-Morales, Carlos.
(2019)
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.
Nature Methods
Academic article
-
Brumpton, Ben Michael;
Fritsche, Lars;
Zheng, Jie;
Nielsen, Jonas Bille;
Mannila, Maria Nastase;
Surakka, Ida.
(2019)
Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition.
Circulation: Genomic and precision medicine
Academic article
-
Richmond, Rebecca C.;
Anderson, Emma L.;
Dashti, Hassan S.;
Jones, Samuel E.;
Lane, Jacqueline M.;
Strand, Linn B.
(2019)
Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study.
The BMJ
Academic article
-
Sun, Yi-Qian;
Brumpton, Ben Michael;
Langhammer, Arnulf;
Chen, Yue;
Kvaløy, Kirsti;
Mai, Xiao-Mei.
(2019)
Adiposity and asthma in adults: a bidirectional Mendelian randomisation analysis of The HUNT Study.
Thorax
Academic article
2018
-
Sun, Yi-Qian;
Brumpton, Ben Michael;
Bonilla, Carolina;
Lewis, Sarah J.;
Burgess, Stephen;
Skorpen, Frank.
(2018)
Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study.
European Respiratory Journal
Academic article
-
Cepelis, Aivaras;
Brumpton, Ben Michael;
Malmo, Vegard;
Laugsand, Lars Erik;
Loennechen, Jan Pål;
Ellekjær, Hanne.
(2018)
Associations of asthma and asthma control with atrial fibrillation risk: Results from the Nord-Trøndelag health study (HUNT).
JAMA cardiology
Academic article
2017
-
Ferreira, Manuel A.;
Vonk, Judith M;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D.
(2017)
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Nature Genetics
Academic article
-
Brumpton, Ben Michael;
Mai, Xiao-Mei;
Langhammer, Arnulf;
Laugsand, Lars Erik;
Janszky, Imre;
Strand, Linn B.
(2017)
Prospective study of insomnia and incident asthma in adults: The HUNT study.
European Respiratory Journal
Academic article
2014
-
Mai, Xiao-Mei;
Brumpton, Ben Michael.
(2014)
Risk factors for the development of asthma in adults: adiposity, metabolic syndrome, mental distress and their interplay.
NTNU-trykk
Doctoral dissertation
Journal publications
-
Howe, Laurence J.;
Brumpton, Ben Michael;
Rasheed, Humaira;
Åsvold, Bjørn Olav;
Davey Smith, George;
Davies, Neil Martin.
(2022)
Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study.
eLIFE
Academic article
-
Bhatta, Laxmi;
Cepelis, Aivaras;
Vikjord, Sigrid Anna Aalberg;
Malmo, Vegard;
Laugsand, Lars Erik;
Dalen, Håvard.
(2021)
Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study.
European Journal of Epidemiology (EJE)
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics
Academic article
-
Zhou, Wei;
Brumpton, Ben Michael;
Kabil, Omer;
Gudmundsson, Julius;
Thorleifsson, Gudmar;
Weinstock, Joshua.
(2020)
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.
Nature Communications
Academic article
-
Surakka, Ida;
Fritsche, Lars;
Zhou, Wei;
Backman, Joshua;
Kosmicki, Jack A.;
Lu, Haocheng.
(2020)
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Nature Communications
Academic article
-
Nielsen, Jonas Bille;
Rom, Oren;
Surakka, Ida;
Graham, Sarah E.;
Zhou, Wei;
Roychowdhury, Tanmoy.
(2020)
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Academic article
-
Brumpton, Ben Michael;
Sanderson, Eleanor;
Heilbron, Karl;
Hartwig, FP;
Harrison, S;
Vie, Gunnhild Åberge.
(2020)
Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses.
Nature Communications
Academic article
-
Moen, Gunn-Helen;
Brumpton, Ben Michael;
Willer, Cristen J.;
Åsvold, Bjørn Olav;
Birkeland, Kåre I.;
Wang, Geng.
(2020)
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort.
Nature Communications
Academic article
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Yue, Chen.
(2020)
Spirometric Classifications of COPD Severity as Predictive
Markers for Clinical Outcomes: The HUNT Study.
American Journal of Respiratory and Critical Care Medicine
Academic article
-
Budu-Aggrey, Ashley;
Brumpton, Ben Michael;
Tyrrell, Jess;
Watkins, Sarah;
Modalsli, Ellen Heilmann;
Celis-Morales, Carlos.
(2019)
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.
Nature Methods
Academic article
-
Brumpton, Ben Michael;
Fritsche, Lars;
Zheng, Jie;
Nielsen, Jonas Bille;
Mannila, Maria Nastase;
Surakka, Ida.
(2019)
Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition.
Circulation: Genomic and precision medicine
Academic article
-
Richmond, Rebecca C.;
Anderson, Emma L.;
Dashti, Hassan S.;
Jones, Samuel E.;
Lane, Jacqueline M.;
Strand, Linn B.
(2019)
Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study.
The BMJ
Academic article
-
Sun, Yi-Qian;
Brumpton, Ben Michael;
Langhammer, Arnulf;
Chen, Yue;
Kvaløy, Kirsti;
Mai, Xiao-Mei.
(2019)
Adiposity and asthma in adults: a bidirectional Mendelian randomisation analysis of The HUNT Study.
Thorax
Academic article
-
Sun, Yi-Qian;
Brumpton, Ben Michael;
Bonilla, Carolina;
Lewis, Sarah J.;
Burgess, Stephen;
Skorpen, Frank.
(2018)
Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study.
European Respiratory Journal
Academic article
-
Cepelis, Aivaras;
Brumpton, Ben Michael;
Malmo, Vegard;
Laugsand, Lars Erik;
Loennechen, Jan Pål;
Ellekjær, Hanne.
(2018)
Associations of asthma and asthma control with atrial fibrillation risk: Results from the Nord-Trøndelag health study (HUNT).
JAMA cardiology
Academic article
-
Ferreira, Manuel A.;
Vonk, Judith M;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D.
(2017)
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Nature Genetics
Academic article
-
Brumpton, Ben Michael;
Mai, Xiao-Mei;
Langhammer, Arnulf;
Laugsand, Lars Erik;
Janszky, Imre;
Strand, Linn B.
(2017)
Prospective study of insomnia and incident asthma in adults: The HUNT study.
European Respiratory Journal
Academic article
Report
-
Mai, Xiao-Mei;
Brumpton, Ben Michael.
(2014)
Risk factors for the development of asthma in adults: adiposity, metabolic syndrome, mental distress and their interplay.
NTNU-trykk
Doctoral dissertation